William D Schlaff

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. doi request reprint Barriers to conducting clinical research in reproductive medicine around the world
    William D Schlaff
    Department of Obstetrics and Gynecology, Thomas Jefferson Medical College, Philadelphia, Pennsylvania, USA
    Fertil Steril 96:801. 2011
  2. pmc Increasing burden of institutional review in multicenter clinical trials of infertility: the Reproductive Medicine Network experience with the Pregnancy in Polycystic Ovary Syndrome (PPCOS) I and II studies
    William D Schlaff
    Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Academic Office Building 1, 12631 E 17th Avenue, Aurora, CO 80045, USA
    Fertil Steril 96:15-8. 2011
  3. ncbi request reprint Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome
    Richard S Legro
    Department of Obstetrics and Gynecology, Pennsylvania State University College of Medicine, M S Hershey Medical Center, Hershey, PA 17033, USA
    N Engl J Med 356:551-66. 2007
  4. pmc Predictors of pregnancy in women with polycystic ovary syndrome
    Mary E Rausch
    Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 94:3458-66. 2009
  5. pmc Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene
    Richard S Legro
    Department of Obstetrics and Gynecology, Pennsylvania State University, M S Hershey Medical Center, 500 University Drive, H103, Hershey, Pennsylvania 17033, USA
    J Clin Endocrinol Metab 93:792-800. 2008
  6. pmc Altering hirsutism through ovulation induction in women with polycystic ovary syndrome
    Lauren W Roth
    University of Colorado, Denver, Aurora, CO, USA
    Obstet Gynecol 119:1151-6. 2012
  7. ncbi request reprint Absence of secretory endometrium after false-positive home urine luteinizing hormone testing
    Peter G McGovern
    Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey, Newark 07103, USA
    Fertil Steril 82:1273-7. 2004
  8. pmc Total testosterone assays in women with polycystic ovary syndrome: precision and correlation with hirsutism
    Richard S Legro
    Department of Obstetrics and Gynecology, Pennsylvania State University, College of Medicine, M S Hershey Medical Center, 500 University Drive, H103, Hershey, Pennsylvania 17033, USA
    J Clin Endocrinol Metab 95:5305-13. 2010
  9. ncbi request reprint The Pregnancy in Polycystic Ovary Syndrome study: baseline characteristics of the randomized cohort including racial effects
    Richard S Legro
    Department of Obstetrics and Gynecology, Pennsylvania State University, Hershey, Pennsylvania 17033, USA
    Fertil Steril 86:914-33. 2006
  10. pmc Establishing a biologic specimens repository for reproductive clinical trials: technical aspects
    Stephen A Krawetz
    Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, USA
    Syst Biol Reprod Med 57:222-7. 2011

Collaborators

Detail Information

Publications12

  1. doi request reprint Barriers to conducting clinical research in reproductive medicine around the world
    William D Schlaff
    Department of Obstetrics and Gynecology, Thomas Jefferson Medical College, Philadelphia, Pennsylvania, USA
    Fertil Steril 96:801. 2011
    ..We asked seven senior and accomplished investigators from around the world to share their experiences conducting research in reproductive medicine...
  2. pmc Increasing burden of institutional review in multicenter clinical trials of infertility: the Reproductive Medicine Network experience with the Pregnancy in Polycystic Ovary Syndrome (PPCOS) I and II studies
    William D Schlaff
    Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Academic Office Building 1, 12631 E 17th Avenue, Aurora, CO 80045, USA
    Fertil Steril 96:15-8. 2011
    ..It is timely to consider whether these changes better protect the interests and safety of human research participants. Clinical trial registration: ClinicalTrials.gov NCT00068861 and NCT00719186...
  3. ncbi request reprint Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome
    Richard S Legro
    Department of Obstetrics and Gynecology, Pennsylvania State University College of Medicine, M S Hershey Medical Center, Hershey, PA 17033, USA
    N Engl J Med 356:551-66. 2007
    ..The polycystic ovary syndrome is a common cause of infertility. Clomiphene and insulin sensitizers are used alone and in combination to induce ovulation, but it is unknown whether one approach is superior...
  4. pmc Predictors of pregnancy in women with polycystic ovary syndrome
    Mary E Rausch
    Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Clin Endocrinol Metab 94:3458-66. 2009
    ..Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. The selection of first-line therapies for ovulation induction is empiric...
  5. pmc Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene
    Richard S Legro
    Department of Obstetrics and Gynecology, Pennsylvania State University, M S Hershey Medical Center, 500 University Drive, H103, Hershey, Pennsylvania 17033, USA
    J Clin Endocrinol Metab 93:792-800. 2008
    ..Clomiphene and insulin sensitizers such as metformin are used to induce ovulation in polycystic ovary syndrome (PCOS), but the ovulatory response is variable, and the causes of this variation are poorly understood...
  6. pmc Altering hirsutism through ovulation induction in women with polycystic ovary syndrome
    Lauren W Roth
    University of Colorado, Denver, Aurora, CO, USA
    Obstet Gynecol 119:1151-6. 2012
    ..We investigated whether women who ovulate in response to treatment with clomiphene citrate, metformin, or both would have greater improvement in hirsutism compared with those who did not ovulate...
  7. ncbi request reprint Absence of secretory endometrium after false-positive home urine luteinizing hormone testing
    Peter G McGovern
    Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey, Newark 07103, USA
    Fertil Steril 82:1273-7. 2004
    ..To examine the proportion of cases with proliferative endometrium on biopsies performed after positive home urine LH testing...
  8. pmc Total testosterone assays in women with polycystic ovary syndrome: precision and correlation with hirsutism
    Richard S Legro
    Department of Obstetrics and Gynecology, Pennsylvania State University, College of Medicine, M S Hershey Medical Center, 500 University Drive, H103, Hershey, Pennsylvania 17033, USA
    J Clin Endocrinol Metab 95:5305-13. 2010
    ..There is no standardized assay of testosterone in women. Liquid chromatography mass spectrometry (LC/MS) has been proposed as the preferable assay by an Endocrine Society Position Statement...
  9. ncbi request reprint The Pregnancy in Polycystic Ovary Syndrome study: baseline characteristics of the randomized cohort including racial effects
    Richard S Legro
    Department of Obstetrics and Gynecology, Pennsylvania State University, Hershey, Pennsylvania 17033, USA
    Fertil Steril 86:914-33. 2006
    ..To report the baseline characteristics and racial differences in the polycystic ovary syndrome (PCOS) phenotype from a large multicenter clinical trial (PPCOS)...
  10. pmc Establishing a biologic specimens repository for reproductive clinical trials: technical aspects
    Stephen A Krawetz
    Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, USA
    Syst Biol Reprod Med 57:222-7. 2011
    ..To facilitate such interoperability, the reagents and protocols that have been adopted by the RMN Biorepository for the collection and storage of serum, blood, saliva and sperm are described...
  11. doi request reprint Physicians' perspectives and practices regarding the fertility management of obese patients
    Isiah D Harris
    Division of Advanced Reproductive Medicine, Department of Obstetrics and Gynecology, University of Colorado Denver, Aurora, Colorado, USA
    Fertil Steril 96:991-2. 2011
    ....
  12. ncbi request reprint Histological dating of timed endometrial biopsy tissue is not related to fertility status
    Christos Coutifaris
    Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Fertil Steril 82:1264-72. 2004
    ..To assess the ability of histological dating to discriminate between women of fertile and infertile couples. The utility of histological dating of endometrium in the evaluation of infertile couples is uncertain...