Research Topics
Genomes and GenesSpecies | Thomas SchillingSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Dynamics and precision in retinoic acid morphogen gradientsThomas F Schilling
Center for Complex Biological Systems, University of California, 92697 2280, Department of Developmental and Cell Biology, University of California, 92697 2300, Electronic address
Curr Opin Genet Dev 22:562-9. 2012....
Fishing for the signals that pattern the faceThomas F Schilling
Department of Developmental and Cell Biology, 4462 Natural Sciences II, University of California, Irvine, CA 92697 2300, USA
J Biol 8:101. 2009..See research article http://www.biomedcentral.com/1471-213X/9/59...
FishNet: an online database of zebrafish anatomyRobert J Bryson-Richardson
The Victor Chang Cardiac Research Institute, 384 Victoria Street, Darlinghurst, Sydney, 2010, Australia
BMC Biol 5:34. 2007....
Considering the zebrafish in a comparative contextThomas F Schilling
Department of Developmental and Cell Biology, University of California, Irvine, California 92697 2300, USA
J Exp Zool B Mol Dev Evol 308:515-22. 2007..Studies of the zebrafish in phylogenetic context provide an opportunity for synergy between communities using these two fundamentally different approaches...- Plasticity in zebrafish hox expression in the hindbrain and cranial neural crestT F Schilling
Molecular Embryology Laboratory, Imperial Cancer Research Fund, London, United Kingdom
Dev Biol 231:201-16. 2001..Thus, consistent with models implicating hox expression in control of segmental identity, plasticity in hox expression correlates with plasticity in final cell fate... - AP2-dependent signals from the ectoderm regulate craniofacial development in the zebrafish embryoRobert D Knight
Department of Developmental and Cell Biology, University of California, Irvine, CA 92697 2300, USA
Development 132:3127-38. 2005.... - Origins of anteroposterior patterning and Hox gene regulation during chordate evolutionT F Schilling
Department of Developmental and Cell Biology, 5210 Bio Sci II, University of California, Irvine, CA 92697 2300, USA
Philos Trans R Soc Lond B Biol Sci 356:1599-613. 2001.... - Skeletal and pigment cell defects in the lockjaw mutant reveal multiple roles for zebrafish tfap2a in neural crest developmentRobert D Knight
Department of Developmental and Cell Biology, University of California, Irvine, California, USA
Dev Dyn 229:87-98. 2004..Developmental Dynamics 229:87-98, 2004... - lockjaw encodes a zebrafish tfap2a required for early neural crest developmentRobert D Knight
Department of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA
Development 130:5755-68. 2003..These studies demonstrate that low is required for early steps in neural crest development and suggest that tfap2a is essential for the survival of a subset of neural crest derivatives... - Tfap2 transcription factors in zebrafish neural crest development and ectodermal evolutionTrevor L Hoffman
Department of Developmental and Cell Biology, University of California, Irvine, California 92697 2305, USA
J Exp Zool B Mol Dev Evol 308:679-91. 2007.... - Requirements for Endothelin type-A receptors and Endothelin-1 signaling in the facial ectoderm for the patterning of skeletogenic neural crest cells in zebrafishSreelaja Nair
Department of Developmental and Cell Biology, University of California, Irvine, 5210 McGaugh Hall, Irvine, CA 92697 2300, USA
Development 134:335-45. 2007..Collectively, our results indicate that Edn1 from the pharyngeal ectoderm signals through Ednra proteins to direct early dorsoventral patterning of the skeletogenic neural crest... - Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skullNaoyuki Wada
Department of Developmental and Cell Biology, University of California, Irvine, 5210 McGaugh Hall, Irvine, CA 92697 2300, USA
Development 132:3977-88. 2005.... - REREa/Atrophin-2 interacts with histone deacetylase and Fgf8 signaling to regulate multiple processes of zebrafish developmentNikki Plaster
Max Planck Institute of Immunobiology, Freiburg, Germany
Dev Dyn 236:1891-904. 2007..We present a model for RERE-dependent patterning in which tissue-specific transcriptional repression, by means of an REREa-HDAC complex, modulates growth factor signaling during embryogenesis... - Chemokine signaling controls endodermal migration during zebrafish gastrulationSreelaja Nair
Department of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA
Science 322:89-92. 2008..This process may have relevance to human gastrointestinal bifurcations and other organ defects... - Ovo1 links Wnt signaling with N-cadherin localization during neural crest migrationSarah Piloto
Department of Developmental and Cell Biology, University of California, Irvine, CA 92697 2300, USA
Development 137:1981-90. 2010..Similar processes probably occur in other cell types in which Wnt signaling promotes migration... - Combinatorial roles for zebrafish retinoic acid receptors in the hindbrain, limbs and pharyngeal archesAngela Linville
Department of Developmental and Cell Biology, Developmental Biology Center, University of California, Irvine, CA 92697, USA
Dev Biol 325:60-70. 2009..These studies reveal novel tissue-specific roles for RARs in controlling the competence and sensitivity of cells to respond to RA... - Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryoRichard J White
Department of Developmental and Cell Biology, University of California Irvine, Irvine, California, United States of America
PLoS Biol 5:e304. 2007..Such control also provides an explanation for the fact that loss of an endogenous RA gradient can be compensated for by RA that is provided in a spatially uniform manner... - Requirements for endoderm and BMP signaling in sensory neurogenesis in zebrafishJochen Holzschuh
Department of Developmental and Cell Biology, University of California, 5438 McGaugh Hall, Irvine, CA 92697 2300, USA
Development 132:3731-42. 2005..Our results show that the endoderm regulates the differentiation of cranial sensory ganglia, which coordinates the cranial nerves with the segments that they innervate... - Development of cartilage and boneYashar Javidan
Department of Developmental and Cell Biology, University of California, Irvine, Irvine, California 92697, USA
Methods Cell Biol 76:415-36. 2004 - Independent roles for retinoic acid in segmentation and neuronal differentiation in the zebrafish hindbrainAngela Linville
Department of Developmental and Cell Biology, University of California, Irvine, CA 92697-2300, USA
Dev Biol 270:186-99. 2004..Thus, in addition to its role in determining rhombomere identities, RA plays a more direct role in the differentiation of subsets of branchiomotor neurons within the hindbrain... - Understanding endothelin-1 function during craniofacial development in the mouse and zebrafishDavid E Clouthier
Department of Molecular, Cellular and Craniofacial Biology, University of Louisville, Kentucky 40292, USA
Birth Defects Res C Embryo Today 72:190-9. 2004.... - Molecular dissection of craniofacial development using zebrafishPamela C Yelick
The Forsyth Institute, Department of Cytokine Biology, and Harvard Forsyth Department of Oral Biology, 140 The Fenway, Boston, MA 02115, USA
Crit Rev Oral Biol Med 13:308-22. 2002..We discuss the potential impact of specialized mutagenesis screens and the future applications of this versatile, vertebrate developmental model system in the molecular dissection of craniofacial development... - Requirement for endoderm and FGF3 in ventral head skeleton formationNicolas B David
U 368 INSERM, Ecole Normale Superieure, 46 rue d Ulm, F 75230 Paris cedex 05, France
Development 129:4457-68. 2002..Together, our results reveal for the first time that the endoderm provides differential cues along the anteroposterior axis to control ventral head skeleton development and demonstrate that this function is mediated in part by Fgf3... - Cranial neural crest and development of the head skeletonRobert D Knight
Centre for Developmental and Biomedical Genetics, Department of Biomedical Sciences, University of Sheffield, South Yorkshire, UK
Adv Exp Med Biol 589:120-33. 2006..We highlight recent genetic studies of craniofacial development in zebrafish that have revealed new tissue interactions and show that the process of CNC development is highly conserved across the vertebrates... - Retinoids signal directly to zebrafish endoderm to specify insulin-expressing beta-cellsDavid Stafford
The Committee on Developmental Biology, The University of Chicago, 1027 East 57th Street, IL 60637, USA
Development 133:949-56. 2006..These findings suggest that RA will have important applications in the quest to induce islets from stem cells for therapeutic uses... - The zebrafish van gogh mutation disrupts tbx1, which is involved in the DiGeorge deletion syndrome in humansTatjana Piotrowski
National Institutes of Health, NICHD, LMG, Bldg 6B, 9000 Rockville Pike, Bethesda, MD 20892, USA
Development 130:5043-52. 2003..Furthermore, we provide evidence for regulatory interactions between vgo/tbx1 and edn1 and hand2, genes that are implicated in the control of pharyngeal arch development and in the etiology of DGS... - Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphé neurones and cranial motoneuronesWill H Norton
Department of Anatomy and Developmental Biology, UCL, Gower Street, London WC1E 6BT, UK
Development 132:645-58. 2005....
Research Grants
- Retinoid Signaling in Neural Patterning in ZebrafishThomas Schilling; Fiscal Year: 2007....
- THE ROLE OF ATROPHIN-2 IN CARTILAGE PATTERNING AND POLARITY IN ZEBRAFISHThomas Schilling; Fiscal Year: 2007..These processes are likely to persist in the adult skeleton, and to be altered in human malformations and diseases of the skeleton. ..
- Retinoid Signaling in Neural Patterning in ZebrafishThomas Schilling; Fiscal Year: 2009....
- Zebrafish in Comparative Context: A SymposiumThomas Schilling; Fiscal Year: 2006....
- Retinoid Signaling in Neural Patterning in ZebrafishThomas Schilling; Fiscal Year: 2005..Aim 3 focuses on a particular tissue interaction that requires RA, between the mesoderm and developing neural tube, by using cell transplantation in RALDH2 mutants to get to the biochemical basis for neural patterning. ..
- Role of Endothelins in Skeletal Patterning in ZebrafishThomas Schilling; Fiscal Year: 2005..abstract_text> ..
- THE ROLE OF ATROPHIN-2 IN CARTILAGE PATTERNING AND POLARITY IN ZEBRAFISHThomas F Schilling; Fiscal Year: 2010..These processes are likely to persist in the adult skeleton, and to be altered in human malformations and diseases of the skeleton. ..