Eugene R Schiff

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. ncbi request reprint Diagnosing and treating hepatitis C virus infection
    Eugene R Schiff
    Schiff Liver Institute Center for Liver Diseases, University of Miami Miller School of Medicine, 1500 NW 12 Ave, Jackson Medical Tower E 1101, Miami, FL 33136, USA
    Am J Manag Care 17:S108-15. 2011
  2. ncbi request reprint Lamivudine and 24 weeks of lamivudine/interferon combination therapy for hepatitis B e antigen-positive chronic hepatitis B in interferon nonresponders
    Eugene R Schiff
    Division of Hepatology, University of Miami, Jackson Medical Towers, 1500 N W 12th Avenue, Suite 1101, Miami, FL 33136, USA
    J Hepatol 38:818-26. 2003
  3. ncbi request reprint Introduction
    Eugene R Schiff
    Division of Hepatology, University of Miami School of Medicine, Miami, Florida 33136, USA
    Am J Med 118:1S-6S. 2005
  4. ncbi request reprint Adefovir dipivoxil therapy for lamivudine-resistant hepatitis B in pre- and post-liver transplantation patients
    Eugene R Schiff
    Center for Liver Diseases, University of Miami, Miami, FL 33136, USA
    Hepatology 38:1419-27. 2003
  5. ncbi request reprint Adefovir dipivoxil for wait-listed and post-liver transplantation patients with lamivudine-resistant hepatitis B: final long-term results
    Eugene Schiff
    Center for Liver Diseases, University of Miami, Miami, FL 33136, USA
    Liver Transpl 13:349-60. 2007
  6. doi request reprint Long-term treatment with entecavir induces reversal of advanced fibrosis or cirrhosis in patients with chronic hepatitis B
    Eugene R Schiff
    University of Miami Hospital and Clinics, Miami, Florida, USA
    Clin Gastroenterol Hepatol 9:274-6. 2011
  7. ncbi request reprint Emerging strategies for pegylated interferon combination therapy
    Eugene R Schiff
    University of Miami School of Medicine, 1500 NW 12 Avenue, Jackson Medical Tower E 1101, Miami, FL 33136, USA
    Nat Clin Pract Gastroenterol Hepatol 4:S17-21. 2007
  8. ncbi request reprint Prevention of mortality from hepatitis B and hepatitis C
    Eugene R Schiff
    Division of Hepatology, Center for Liver Disease, University of Miami School of Medicine, Miami, FL 33136, USA
    Lancet 368:896-7. 2006
  9. ncbi request reprint Outcomes in liver transplant recipients with hepatitis B virus: resistance and recurrence patterns from a large transplant center over the last decade
    Guy W Neff
    Center for Liver Diseases, Department of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA
    Liver Transpl 10:1372-8. 2004
  10. ncbi request reprint Treatment of established recurrent hepatitis C in liver-transplant recipients with pegylated interferon-alfa-2b and ribavirin therapy
    Guy W Neff
    Center for Liver Diseases, Division of GI Transplant, Department of Medicine, University of Miami, Miami, FL, USA
    Transplantation 78:1303-7. 2004

Detail Information

Publications68

  1. ncbi request reprint Diagnosing and treating hepatitis C virus infection
    Eugene R Schiff
    Schiff Liver Institute Center for Liver Diseases, University of Miami Miller School of Medicine, 1500 NW 12 Ave, Jackson Medical Tower E 1101, Miami, FL 33136, USA
    Am J Manag Care 17:S108-15. 2011
    ..Several new therapies for HCV infection are in development. Protease inhibitors are expected to become the new standard of care for nonresponders, with the potential to become a first-line treatment for chronic HCV infection...
  2. ncbi request reprint Lamivudine and 24 weeks of lamivudine/interferon combination therapy for hepatitis B e antigen-positive chronic hepatitis B in interferon nonresponders
    Eugene R Schiff
    Division of Hepatology, University of Miami, Jackson Medical Towers, 1500 N W 12th Avenue, Suite 1101, Miami, FL 33136, USA
    J Hepatol 38:818-26. 2003
    ..We assessed lamivudine treatment, with or without added interferon, in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B who had failed interferon therapy previously...
  3. ncbi request reprint Introduction
    Eugene R Schiff
    Division of Hepatology, University of Miami School of Medicine, Miami, Florida 33136, USA
    Am J Med 118:1S-6S. 2005
  4. ncbi request reprint Adefovir dipivoxil therapy for lamivudine-resistant hepatitis B in pre- and post-liver transplantation patients
    Eugene R Schiff
    Center for Liver Diseases, University of Miami, Miami, FL 33136, USA
    Hepatology 38:1419-27. 2003
    ..In conclusion, 48 weeks of adefovir dipivoxil resulted in significant improvements in virologic, biochemical, and clinical parameters in CHB patients pre- and post-LT with lamivudine-resistant HBV...
  5. ncbi request reprint Adefovir dipivoxil for wait-listed and post-liver transplantation patients with lamivudine-resistant hepatitis B: final long-term results
    Eugene Schiff
    Center for Liver Diseases, University of Miami, Miami, FL 33136, USA
    Liver Transpl 13:349-60. 2007
    ..In conclusion, adefovir dipivoxil is effective and safe in wait-listed or posttransplantation CHB patients with lamivudine-resistant HBV and prevents graft reinfection with or without HBIg...
  6. doi request reprint Long-term treatment with entecavir induces reversal of advanced fibrosis or cirrhosis in patients with chronic hepatitis B
    Eugene R Schiff
    University of Miami Hospital and Clinics, Miami, Florida, USA
    Clin Gastroenterol Hepatol 9:274-6. 2011
    ..Patients with advanced fibrosis or cirrhosis, who received long-term entecavir treatment, were evaluated for improvement in liver histology...
  7. ncbi request reprint Emerging strategies for pegylated interferon combination therapy
    Eugene R Schiff
    University of Miami School of Medicine, 1500 NW 12 Avenue, Jackson Medical Tower E 1101, Miami, FL 33136, USA
    Nat Clin Pract Gastroenterol Hepatol 4:S17-21. 2007
    ..Challenges include the prevention of recurrent HCV infection in liver-transplant recipients and development of a safe and effective HCV vaccine...
  8. ncbi request reprint Prevention of mortality from hepatitis B and hepatitis C
    Eugene R Schiff
    Division of Hepatology, Center for Liver Disease, University of Miami School of Medicine, Miami, FL 33136, USA
    Lancet 368:896-7. 2006
  9. ncbi request reprint Outcomes in liver transplant recipients with hepatitis B virus: resistance and recurrence patterns from a large transplant center over the last decade
    Guy W Neff
    Center for Liver Diseases, Department of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA
    Liver Transpl 10:1372-8. 2004
    ..In conclusion, pre-LTx HBV viremia should be considered in planning post-LTx prophylaxis. Trials to evaluate oral antiviral agents in combination with or without HBIg therapy are needed...
  10. ncbi request reprint Treatment of established recurrent hepatitis C in liver-transplant recipients with pegylated interferon-alfa-2b and ribavirin therapy
    Guy W Neff
    Center for Liver Diseases, Division of GI Transplant, Department of Medicine, University of Miami, Miami, FL, USA
    Transplantation 78:1303-7. 2004
    ..We present data from a retrospective review in liver-transplant recipients suffering from HCV recurrence that were treated with pegylated alpha-2b interferon and ribavirin...
  11. ncbi request reprint Prediction of sustained virological response in liver transplant recipients with recurrent hepatitis C virus following combination pegylated interferon alfa-2b and ribavirin therapy using tissue hepatitis C virus reverse transcriptase polymerase chain rea
    Guy W Neff
    Center for Liver Diseases and Division of GI Transplant, Department of Medicine, University of Miami, FL 33136, USA
    Liver Transpl 10:595-8. 2004
    ..In conclusion, direct detection of HCV RNA by RT-PCR of liver tissue appears to more effectively predict SVR following pegylated interferon and ribavirin therapy than the conventional use of serum...
  12. ncbi request reprint Lamivudine monoprophylaxis for liver transplant recipients with non-replicating hepatitis B virus infection
    Hideo Yoshida
    Division of Liver GI Transplantation, Department of Surgery, University of Miami School of Medicine, Miami, FL 33136, USA
    Clin Transplant 21:166-71. 2007
    ..Background: The aim of this study was to evaluate the efficacy of lamivudine (LAM) monoprophylaxis for patients with non-replicating hepatitis B virus (HBV) infection at orthotopic liver transplantation (OLT)...
  13. ncbi request reprint Pretreatment laparoscopic appearance of the liver can predict response to combination therapy with interferon alpha 2B and ribavirin in chronic hepatitis C
    Jasmohan S Bajaj
    Center for Liver Diseases, University of Miami School of Medicine, Miami, Florida 33136, USA
    Gastrointest Endosc 58:380-3. 2003
    ..The aim of this study was to determine whether the pretreatment laparoscopic appearance of the liver is an additional predictor of response to combination therapy with interferon and ribavirin in patients with hepatitis C...
  14. ncbi request reprint Reliability of histopathologic assessment for the differentiation of recurrent hepatitis C from acute rejection after liver transplantation
    Arie Regev
    Division of Hepatology, Center for Liver Diseases, University of Miami School of Medicine, Miami, FL 33136, USA
    Liver Transpl 10:1233-9. 2004
    ..Histopathologic assessment should be used cautiously for the differentiation of RHC from ACR post-LT...
  15. doi request reprint Outcomes of liver transplantation in patients with cirrhosis due to nonalcoholic steatohepatitis versus patients with cirrhosis due to alcoholic liver disease
    Vishal Bhagat
    Center for Liver Diseases, University of Miami Leonard M Miller School of Medicine, Miami, FL, USA
    Liver Transpl 15:1814-20. 2009
    ..Acute rejection and recurrent steatohepatitis were significantly more frequent in the NASH group but did not lead to higher rates of retransplantation...
  16. pmc Prevention and treatment of recurrent Hepatitis B after liver transplantation: the current role of nucleoside and nucleotide analogues
    Ian R Schreibman
    Center for Liver Diseases, Division of Hepatology, University of Miami Leonard M Miller School of Medicine, Miami, FL, USA
    Ann Clin Microbiol Antimicrob 5:8. 2006
    ..Particular attention will be paid to the newer nucleoside and nucleotide analogs and the direction for future strategies to treat HBV in the post transplant setting...
  17. ncbi request reprint Outcomes after orthotopic liver transplantation in 15 HIV-infected patients
    Ian Schreibman
    Center for Liver Diseases, Division of Hepatology, University of Miami Leonard M Miller School of Medicine, Miami, FL 33136, USA
    Transplantation 84:697-705. 2007
    ..Highly active antiretroviral therapy (HAART) has led to an increasing number of successful OLTs. The aim of this study was to examine survival and cause-specific mortality in HIV-infected patients after OLT at our institution...
  18. ncbi request reprint Imatinib mesylate (gleevec) hepatotoxicity
    Ayse L Mindikoglu
    Center for Liver Diseases, Division of Hepatology, University of Miami Leonard M Miller School of Medicine, Miami, FL 33136, USA
    Dig Dis Sci 52:598-601. 2007
  19. ncbi request reprint Spontaneous clearance of hepatitis C virus after liver transplantation in two patients coinfected with hepatitis C virus and human immunodeficiency virus
    Vishal Bhagat
    Center for Liver Diseases, Division of Hepatology, Leonard M Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Liver Transpl 14:92-5. 2008
    ..Spontaneous clearance of chronic HCV infection can occur in HIV-HCV-coinfected patients after liver transplantation. The mechanism of this phenomenon remains unclear...
  20. ncbi request reprint Competing risks analysis of predictors of delisting owing to tumor progression in liver transplant candidates with hepatocellular carcinoma
    Noriyo Yamashiki
    Division of Transplantation, Department of Surgery, University of Miami School of Medicine, Miami, FL, USA
    Am J Transplant 4:774-81. 2004
    ..001). In conclusion, the initial AFP level may be useful along with tumor stage in defining an urgency score for liver transplant candidates with HCC...
  21. ncbi request reprint Does the heterozygous state of alpha-1 antitrypsin deficiency have a role in chronic liver diseases? Interim results of a large case-control study
    Arie Regev
    Division of Hepatology, Center for Liver Diseases, University of Miami, Leonard M Miller School of Medicine, FL 33136, USA
    J Pediatr Gastroenterol Nutr 43:S30-5. 2006
    ..The role of the heterozygous PiZ state of alpha-1 antitrypsin deficiency (alpha1ATD) in the pathogenesis of chronic liver disease (LD) is still a matter of controversy...
  22. ncbi request reprint Budd-Chiari-like presentation of hepatic adenoma
    Abhasnee Sobhonslidsuk
    Center for Liver Diseases, Department of Medicine, University of Miami School of Medicine, Miami, USA
    J Gastroenterol Hepatol 20:653-6. 2005
    ..The lesion compressed the hepatic vein and created an early stage of Budd-Chiari syndrome. Tumor resection was carried out successfully. The final diagnosis of this case was multiple hepatic adenomas...
  23. ncbi request reprint Acquired hepatocerebral degeneration in a patient with HCV cirrhosis: complete resolution with subsequent recurrence after liver transplantation
    Luis Servin-Abad
    Division of Hepatology, Center for Liver Diseases, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Liver Transpl 12:1161-5. 2006
    ..A third OLT led again to disappearance of the clinical and radiological manifestations of AHD. AHD may show complete resolution after OLT; however it may rapidly recur following recurrent liver disease or graft dysfunction...
  24. ncbi request reprint Beneficial effects of topical testosterone replacement in patients with end-stage liver disease
    Guy W Neff
    Center for Liver Diseases, Division of GI Transplant, Department of Medicine, University of Miami, Miami, Florida, USA
    Dig Dis Sci 49:1186-9. 2004
  25. ncbi request reprint Alcohol and hepatitis C
    Kamran Safdar
    Center for Liver Diseases, Division of Hepatology, Department of Medicine, University of Miami, Miami, Florida 33136, USA
    Semin Liver Dis 24:305-15. 2004
    ..Alcohol abuse causes decreased response to interferon treatment in HCV patients. It is therefore necessary for patients with HCV infection to abstain from alcohol consumption...
  26. ncbi request reprint Histopathological changes after microwave coagulation therapy for patients with hepatocellular carcinoma: review of 15 explanted livers
    Noriyo Yamashiki
    Division of Hepatology, Department of Medicine, University of Miami School of Medicine, Miami, Florida, USA
    Am J Gastroenterol 98:2052-9. 2003
    ..However, pathological changes in liver tissue after this therapy have not been well described. We examined the histological changes of HCC after MCT observed in explanted livers in relation to CT findings...
  27. ncbi request reprint Hepatitis B virus reactivation after cytotoxic chemotherapy: the disease and its prevention
    Ayse L Mindikoglu
    Center for Liver Diseases, Division of Hepatology, University of Miami Leonard M Miller School of Medicine, Miami, Florida, USA
    Clin Gastroenterol Hepatol 4:1076-81. 2006
    ..Prophylactic treatment with a nucleoside or nucleotide analogue should be considered strongly to prevent HBV reactivation in these patients...
  28. ncbi request reprint Predictors of cirrhosis in Hispanic patients with nonalcoholic steatohepatitis
    Waleed M Alazmi
    Division of Gastroenterology, Center for Liver Diseases, University of Miami Leonard M Miller School of Medicine, Miami, Florida 33136, USA
    Dig Dis Sci 51:1725-9. 2006
    ..Age was an independent predictor in both groups, however, AST/ALT ratio was found to be an independent predictor of cirrhosis only in Hispanic patients, and diabetes mellitus only in non-Hispanic patients...
  29. ncbi request reprint Relapsing polychondritis, chronic hepatitis C virus infection, and mixed cryoglobulemia
    Ivonne Herrera
    Department of Medicine, University of Miami School of Medicine, Miami, FL, USA
    Semin Arthritis Rheum 33:388-403. 2004
    ..Review of relapsing polychondritis (RP) and its association to chronic hepatitis C virus (HCV) infection and mixed cryoglobulinemia...
  30. ncbi request reprint Orthotopic liver transplantation in patients with human immunodeficiency virus and end-stage liver disease
    Guy W Neff
    Department of Medicine, Division of GI Transplant, University of Miami, Miami, FL 33136, USA
    Liver Transpl 9:239-47. 2003
    ..Given the complex pharmacologic interactions between the protease inhibitors and tacrolimus, careful monitoring, and attention is required to prevent toxicity or underdosing...
  31. ncbi request reprint Liver disease in the elderly
    A Regev
    Division of Hepatology, Center for Liver Diseases, University of Miami School of Medicine, Miami, Florida, USA
    Gastroenterol Clin North Am 30:547-63, x-xi. 2001
    ..Although there are no liver diseases specific to advanced age, the presentation, clinical course and management of liver diseases in the elderly may differ in important respects from those of younger individuals...
  32. ncbi request reprint Dilatation of biliary strictures through the afferent limb of a Roux-en-Y choledochojejunostomy in patients with sclerosing cholangitis
    D G Hutson
    Department of Surgery, University of Miami School of Medicine, Florida 33101, USA
    World J Surg 25:1251-3. 2001
    ..Six patients are presently alive with an average survival of 159 months. The study suggests that a combination of repeated dilatations combined with transplantation is the approach of choice in selected patients...
  33. doi request reprint An update on the hepatitis E virus
    Seth N Sclair
    Department of Medicine, Division of Hepatology, Schiff Center for Liver Diseases, University of Miami Miller School of Medicine, Miami, FL, USA
    Curr Gastroenterol Rep 15:304. 2013
    ..Lastly, two vaccines have been developed and studied in clinical trials, with excellent results...
  34. ncbi request reprint Focal nodular hyperplasia in identical twins
    Ayse L Mindikoglu
    Center for Liver Diseases, Division of Hepatology, Department of Surgery, University of Miami School of Medicine, Miami, Florida 33136, USA
    Am J Gastroenterol 100:1616-9. 2005
    ..This case report strongly supports the theory of a congenital vascular anomaly playing a major role in the etiology of focal nodular hyperplasia...
  35. ncbi request reprint Multiple normal deliveries in a woman with severe portal hypertension due to congenital hepatic fibrosis: the importance of preserved hepatocellular function
    Ayse L Mindikoglu
    Center for Liver Diseases, Division of Hepatology, University of Miami Leonard M Miller School of Medicine, Miami, Florida 33136, USA
    Am J Gastroenterol 100:2359-61. 2005
    ....
  36. ncbi request reprint Epithelioid hemangioendothelioma of the liver
    Ayse L Mindikoglu
    Center for Liver Diseases, Division of Hepatology, University of Miami School of Medicine, Miami, Florida, USA
    Clin Gastroenterol Hepatol 3:xxxii. 2005
  37. ncbi request reprint Recombinant leukocyte interferon, doxorubicin, and 5FUDR in patients with hepatocellular carcinoma-A phase II trial
    Lynn G Feun
    Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Avenue, Miami, Florida, USA
    J Cancer Res Clin Oncol 129:17-20. 2003
    ..To study the combination of 5FUDR, recombinant leukocyte interferon (IFN), and doxorubicin in patients with unresectable hepatocellular carcinoma...
  38. ncbi request reprint Hepatitis C and alcohol
    Eugene R Schiff
    Division of Hepatology, University of Miami School of Medicine, Miami, Florida, USA
    Alcohol Res Health 27:232-9. 2003
    ..Research areas that have the greatest potential for developing more effective treatment options include HCV virology, immunology, animal models, and the mechanisms of liver injury...
  39. ncbi request reprint Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection
    Arie Regev
    Division of Hepatology, Center for Liver Diseases, University of Miami School of Medicine, Florida 33136, USA
    Am J Gastroenterol 97:2614-8. 2002
    ....
  40. ncbi request reprint Acetaminophen safety and hepatotoxicity--where do we go from here?
    Patrick J Amar
    University of Miami Miller School of Medicine, Division of Hepatology, Miami, Florida 33136, USA
    Expert Opin Drug Saf 6:341-55. 2007
    ..Additionally, expert opinion is presented herein to aid in reducing the frequency and severity of liver injury from acetaminophen...
  41. ncbi request reprint A retrospective review of sirolimus (Rapamune) therapy in orthotopic liver transplant recipients diagnosed with chronic rejection
    Guy W Neff
    University of Miami, Department of Medicine, Miami, FL 33136, USA
    Liver Transpl 9:477-83. 2003
    ..Recombinant erythropoietin was started in 5 of 21 patients. Sirolimus serum levels were found to be greater than 20 ng/dL in 12 patients. Sirolimus was discontinued in 9 patients,..
  42. doi request reprint High frequency of genotype D and spontaneous hepatitis B virus genomic mutations among Haitians in a multiethnic North American population
    Claudia A Couto
    Department of Internal Medicine and Alfa Gastroenterology Institute, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil
    J Clin Gastroenterol 47:83-8. 2013
    ..We aimed to determine HBV genotype, precore (PC), and basal core promoter region (BCP) mutations in a HBV multiethnic South Florida population...
  43. doi request reprint Combined central retinal vein and central retinal artery occlusions and neovascular glaucoma associated with interferon treatment
    Aleksandra V Rachitskaya
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 N W 17th Street, Miami, FL 33136, USA
    Eur J Ophthalmol 22:284-7. 2012
    ..Interferon retinopathy is associated with ischemic retinal cotton-wool spots. This case illustrates how IFN can lead to severe and sight-threatening retinal ischemia...
  44. ncbi request reprint Diagnostic laparoscopy in radiation-induced liver disease
    Eduardo B V da Silveira
    Division of Hepatology, University of Miami School of Medicine, Miami, Florida, USA
    Gastrointest Endosc 55:432-4. 2002
  45. ncbi request reprint Prediction of survival outcome of ICU patients awaiting orthotopic liver transplantation
    A Sobhonslidsuk
    Center for Liver Diseases, University of Miami, Miami, Florida 33136, USA
    Transplant Proc 34:1223-5. 2002
  46. ncbi request reprint Impact of histological grade of hepatocellular carcinoma on the outcome of liver transplantation
    S Tamura
    Division of Transplantation, Department of Surgery, University of Miami School of Medicine, 1801 NW Ninth Ave, Highland Professional Building, Suite 511, Miami, FL 33136, USA
    Arch Surg 136:25-30; discussion 31. 2001
    ..However, before altering the current OLT selection criteria for patients with HCC, prospective studies are required to confirm the impact of histological grade on clinical outcome...
  47. ncbi request reprint Drug therapy for hepatitis B
    A Regev
    Division of Hepatology, Center for Liver Diseases, University of Miami School of Medicine, Miami, Fla, USA
    Adv Intern Med 46:107-35. 2001
    ..This combination may act synergistically against HBV and delay or prevent the development of drug-resistant mutants...
  48. ncbi request reprint Large cystic lesions of the liver in adults: a 15-year experience in a tertiary center
    A Regev
    Department of Internal Medicine, University of Miami School of Medicine, FL, USA
    J Am Coll Surg 193:36-45. 2001
    ..Malignant transformation is an uncommon but real risk. Open resection is a safe and effective treatment for hepatobiliary cystadenoma, and is associated with a low recurrence rate...
  49. ncbi request reprint Nyquil-associated liver injury
    R T Foust
    University of Miami School of Medicine, Florida
    Am J Gastroenterol 84:422-5. 1989
    ..We report two cases of unintentional liver injury associated with ingestion of Nyquil, a liquid cold remedy containing acetaminophen and 25% alcohol...
  50. doi request reprint Effect of pretransplant hepatitis C virus RNA status on posttransplant outcome
    C G Nudo
    Center for Liver Diseases, Division of Hepatology, University of Miami, Leonard M Miller School of Medicine, Miami, Florida 33136, USA
    Transplant Proc 40:1449-55. 2008
    ..8%/75.6% and 89.6%/77.8% for RNA(-) and (+) groups, respectively (P = .77). In conclusion, RNA(-)-transplanted patients displayed lower VR and longer time to HR. The SVR patients showed lower VR and HR compared to ETR and RNA(+) patients...
  51. ncbi request reprint Sirolimus therapy in orthotopic liver transplant recipients with calcineurin inhibitor related chronic renal insufficiency
    G W Neff
    University of Miami, Miami, Florida, USA
    Transplant Proc 35:3029-31. 2003
    ..Our clinical experience has revealed sirolimus to be an effective agent in treating renal insufficiency related to calcineurin inhibitor toxicity...
  52. ncbi request reprint Predictors of HBeAg loss after lamivudine treatment for chronic hepatitis B
    Robert P Perrillo
    Section of Gastroenterology and Hepatology, Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA
    Hepatology 36:186-94. 2002
    ..Asians and Caucasians had similar rates of response to lamivudine at comparable ALT levels...
  53. ncbi request reprint A treatment algorithm for the management of chronic hepatitis B virus infection in the United States: an update
    Emmet B Keeffe
    Division of Gastroenterology and Hepatology, Stanford University Medical Center, CA 94304, USA
    Clin Gastroenterol Hepatol 4:936-62. 2006
    ..Issues for consideration include efficacy, safety, incidence of resistance, method of administration, and cost...
  54. ncbi request reprint Epoetin alfa maintains ribavirin dose in HCV-infected patients: a prospective, double-blind, randomized controlled study
    Nezam H Afdhal
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Gastroenterology 126:1302-11. 2004
    ..This study assessed whether epoetin alfa could maintain RBV dose, improve quality of life (QOL), and increase hemoglobin (Hb) in anemic HCV-infected patients...
  55. ncbi request reprint Long-term safety of lamivudine treatment in patients with chronic hepatitis B
    Anna S F Lok
    Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, 48109 0362, USA
    Gastroenterology 125:1714-22. 2003
    ..The aim of this analysis was to determine the incidence of hepatitis flares, hepatic decompensation, and liver-disease-related (LDR) serious adverse events (SAE) during long-term lamivudine treatment...
  56. ncbi request reprint Tenofovir therapy for lamivudine resistance following liver transplantation
    Guy W Neff
    College of Medicine, University of Cincinnati, 231 Albert Sabin Way, MSB Room 6560, Cincinnati, OH 45267 0595, USA
    Ann Pharmacother 38:1999-2004. 2004
    ..Resistant hepatitis B virus (HBV) strains develop in 30% of liver transplant recipients treated with lamivudine within 2 years from the time of transplantation...
  57. ncbi request reprint Epoetin alfa improves quality of life in anemic HCV-infected patients receiving combination therapy
    Paul J Pockros
    Scripps Clinic, La Jolla, CA 92037, USA
    Hepatology 40:1450-8. 2004
    ..Hb improvement was an independent predictor of HRQL improvement in these patients. In conclusion, epoetin alfa provided clinically significant HRQL improvement in HCV-infected patients receiving IFN/RBV therapy...
  58. ncbi request reprint Comparison of three commercially available assays for HCV RNA using the international unit standard: implications for management of patients with chronic hepatitis C virus infection in clinical practice
    Mitchell L Shiffman
    Hepatology Section, Virginia Commonwealth University Health System Medical College of Virginia, Richmond, Virginia 23298, USA
    Am J Gastroenterol 98:1159-66. 2003
    ..The present study was performed to evaluate the impact of the international unit standard for measuring HCV RNA in the management of patients with chronic hepatitis C virus (HCV) infection...
  59. ncbi request reprint A United States compassionate use study of lamivudine treatment in nontransplantation candidates with decompensated hepatitis B virus-related cirrhosis
    Hie Won L Hann
    Department of Medicine, Jefferson Medical College, 1025 Walnut Street Room 910, Philadelphia, PA 19107, USA
    Liver Transpl 9:49-56. 2003
    ..Additional studies of lamivudine in combination with other antivirals are indicated for the large population of patients worldwide with advanced HBV-related cirrhosis and inadequate access to liver transplantation...
  60. ncbi request reprint A dose-ranging study of the efficacy and tolerability of entecavir in Lamivudine-refractory chronic hepatitis B patients
    Ting Tsung Chang
    National Cheng Kung University Medical College, Tainan, Taiwan
    Gastroenterology 129:1198-209. 2005
    ..This randomized, dose-ranging, phase 2 study compared the efficacy and safety of entecavir with lamivudine in lamivudine-refractory patients...
  61. ncbi request reprint Histological outcome during long-term lamivudine therapy
    Jules L Dienstag
    Gastrointestinal Unit Medical Services, Massachusetts General Hospital, Boston, MA 02114, USA
    Gastroenterology 124:105-17. 2003
    ..One year of lamivudine for chronic hepatitis B results in histologic improvement. We aimed to assess the histological impact of longer-term treatment...
  62. ncbi request reprint Chronic hepatitis B: a critical appraisal of current approaches to therapy
    Robert P Perrillo
    Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA
    Clin Gastroenterol Hepatol 4:233-48. 2006
    ..Expert opinions may differ from those of practicing hepatologists and gastroenterologists. We aimed to explore this issue further after a critical review of the literature...
  63. ncbi request reprint A treatment algorithm for the management of chronic hepatitis B virus infection in the United States
    Emmet B Keeffe
    Stanford University Medical Center, 750 Welch Road, Suite 210, Palo Alto, California 94304 1509, USA
    Clin Gastroenterol Hepatol 2:87-106. 2004
    ....
  64. doi request reprint Alcohol consumption by cirrhotic subjects: patterns of use and effects on liver function
    Michael R Lucey
    Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 5124, USA
    Am J Gastroenterol 103:1698-706. 2008
    ....
  65. pmc Cost of preventing variceal rebleeding with transjugular intrahepatic portal systemic shunt and distal splenorenal shunt
    Thomas D Boyer
    Department of Medicine, University of Arizona, Liver Research Institute, Tucson, AZ 85724, USA
    J Hepatol 48:407-14. 2008
    ..We examined the cost and cost effectiveness of distal splenorenal shunt (DSRS) and transjugular intrahepatic portosystemic shunt (TIPS) in the prevention of variceal rebleeding...
  66. ncbi request reprint Colchicine treatment of alcoholic cirrhosis: a randomized, placebo-controlled clinical trial of patient survival
    Timothy R Morgan
    VA Long Beach Healthcare Systems, Long Beach, CA 90822, USA
    Gastroenterology 128:882-90. 2005
    ..Colchicine improved survival and reversed cirrhosis in several small clinical trials. We compared the efficacy and safety of long-term colchicine, as compared with placebo, in patients with advanced alcoholic cirrhosis...
  67. ncbi request reprint Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C
    Paul J Pockros
    Division of Gastroenterology and Hepatology, Scripps Clinic, La Jolla, CA 92037, USA
    Hepatology 46:324-9. 2007
    ..Longer studies to assess potential effects of IDN-6556 on liver inflammation and fibrosis are merited...
  68. doi request reprint Value of fibrosis markers for staging liver fibrosis in patients with precirrhotic alcoholic liver disease
    Charles S Lieber
    James J Peters Veterans Affairs Medical Center, Bronx, New York 10468, USA
    Alcohol Clin Exp Res 32:1031-9. 2008
    ..Moreover, a diagnostic algorithm including 3 serum markers (TIMP1, PIIINP, HA) and age has been proposed to accurately detect fibrosis with acceptable levels of sensitivity/specificity in a chronic hepatitis C subgroup...