M H Schieber

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. doi request reprint Mirror neurons: reflecting on the motor cortex and spinal cord
    Marc H Schieber
    Department of Neurology, University of Rochester, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
    Curr Biol 23:R151-2. 2013
  2. pmc Dissociating motor cortex from the motor
    Marc H Schieber
    Department of Neurology, University of Rochester, 601 Elmwood Avenue, Box 673, Rochester, NY 14642, USA
    J Physiol 589:5613-24. 2011
  3. pmc Selective activation of human finger muscles after stroke or amputation
    Marc H Schieber
    Department of Neurology, University of Rochester, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
    Adv Exp Med Biol 629:559-75. 2009
  4. ncbi request reprint Partial reconstruction of muscle activity from a pruned network of diverse motor cortex neurons
    Marc H Schieber
    Department of Neurology, Neurobiology and Anatomy, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    J Neurophysiol 97:70-82. 2007
  5. ncbi request reprint A spectrum from pure post-spike effects to synchrony effects in spike-triggered averages of electromyographic activity during skilled finger movements
    Marc H Schieber
    University of Rochester Medical Center, Dept of Neurology, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
    J Neurophysiol 94:3325-41. 2005
  6. ncbi request reprint Hand function: peripheral and central constraints on performance
    Marc H Schieber
    Department of Neurology, University of Rochester Medical Center, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
    J Appl Physiol 96:2293-300. 2004
  7. ncbi request reprint Motor control: basic units of cortical output?
    Marc H Schieber
    University of Rochester Medical Center, Department of Neurology, 601 Elmwood Avenue, Rochester, New York 14642, USA
    Curr Biol 14:R353-4. 2004
  8. ncbi request reprint Motor cortex and the distributed anatomy of finger movements
    Marc H Schieber
    Department of Neurology, University of Rochester School of Medicine and Dentistry Rochester, New York 14642, USA
    Adv Exp Med Biol 508:411-6. 2002
  9. ncbi request reprint Primary motor cortex reorganization in a long-term monkey amputee
    M H Schieber
    Department of Neurology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Somatosens Mot Res 14:157-67. 1997
  10. ncbi request reprint Somatotopic gradients in the distributed organization of the human primary motor cortex hand area: evidence from small infarcts
    M H Schieber
    Department of Neurology, Center for Visual Science, and the Brain Injury Rehabilitation Program at St Mary s Hospital, University of Rochester School of Medicine and Dentistry, New York 14642, USA
    Exp Brain Res 128:139-48. 1999

Collaborators

Detail Information

Publications31

  1. doi request reprint Mirror neurons: reflecting on the motor cortex and spinal cord
    Marc H Schieber
    Department of Neurology, University of Rochester, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
    Curr Biol 23:R151-2. 2013
    ....
  2. pmc Dissociating motor cortex from the motor
    Marc H Schieber
    Department of Neurology, University of Rochester, 601 Elmwood Avenue, Box 673, Rochester, NY 14642, USA
    J Physiol 589:5613-24. 2011
    ..The natural ability of motor cortex neurons under voluntarily control to become dissociated from bodily movement may underlie the utility of this cortical area for controlling brain-computer interfaces...
  3. pmc Selective activation of human finger muscles after stroke or amputation
    Marc H Schieber
    Department of Neurology, University of Rochester, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
    Adv Exp Med Biol 629:559-75. 2009
    ..We infer that voluntary motor output patterns that normally control finger movements after amputation may become diverted to remaining proximal muscles...
  4. ncbi request reprint Partial reconstruction of muscle activity from a pruned network of diverse motor cortex neurons
    Marc H Schieber
    Department of Neurology, Neurobiology and Anatomy, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    J Neurophysiol 97:70-82. 2007
    ....
  5. ncbi request reprint A spectrum from pure post-spike effects to synchrony effects in spike-triggered averages of electromyographic activity during skilled finger movements
    Marc H Schieber
    University of Rochester Medical Center, Dept of Neurology, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
    J Neurophysiol 94:3325-41. 2005
    ....
  6. ncbi request reprint Hand function: peripheral and central constraints on performance
    Marc H Schieber
    Department of Neurology, University of Rochester Medical Center, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
    J Appl Physiol 96:2293-300. 2004
    ..We review this evidence, with a particular emphasis on how these constraints extend through the neuromuscular system from the behavioral aspects of finger movements and forces to the control of the hand from the motor cortex...
  7. ncbi request reprint Motor control: basic units of cortical output?
    Marc H Schieber
    University of Rochester Medical Center, Department of Neurology, 601 Elmwood Avenue, Rochester, New York 14642, USA
    Curr Biol 14:R353-4. 2004
    ..Observing movement evoked by stimulating a single cortical neuron has proven technically impossible - until now. A new study using intracellular stimulation has revealed that the basic unit of cortical output is not necessarily basic...
  8. ncbi request reprint Motor cortex and the distributed anatomy of finger movements
    Marc H Schieber
    Department of Neurology, University of Rochester School of Medicine and Dentistry Rochester, New York 14642, USA
    Adv Exp Med Biol 508:411-6. 2002
    ..Distinct functional groups of M1 neurones that might control particular finger movements were identified inconsistently. We therefore hypothesize that M1 neurones are a very diverse network controlling finger movements...
  9. ncbi request reprint Primary motor cortex reorganization in a long-term monkey amputee
    M H Schieber
    Department of Neurology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Somatosens Mot Res 14:157-67. 1997
    ....
  10. ncbi request reprint Somatotopic gradients in the distributed organization of the human primary motor cortex hand area: evidence from small infarcts
    M H Schieber
    Department of Neurology, Center for Visual Science, and the Brain Injury Rehabilitation Program at St Mary s Hospital, University of Rochester School of Medicine and Dentistry, New York 14642, USA
    Exp Brain Res 128:139-48. 1999
    ....
  11. ncbi request reprint Inactivation of the ventral premotor cortex biases the laterality of motoric choices
    M H Schieber
    Department of Neurology, University of Rochester Medical Center, NY 14642, USA
    Exp Brain Res 130:497-507. 2000
    ....
  12. ncbi request reprint Tension distribution to the five digits of the hand by neuromuscular compartments in the macaque flexor digitorum profundus
    M H Schieber
    Departments of Neurology and of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Neurosci 21:2150-8. 2001
    ..We conclude that the macaque FDP consists of four neuromuscular compartments, each of which provides a distinct distribution of tension to multiple digits...
  13. ncbi request reprint Training and synchrony in the motor system
    Marc H Schieber
    Department of Neurology, The Center for Visual Science, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Neurosci 22:5277-81. 2002
    ..Synchronization among neurons with relatively direct connections to spinal alpha-motoneuron pools, including motor cortex neurons, may increase as a repertoire of skilled movements is acquired and practiced during long-term training...
  14. ncbi request reprint Reduced muscle selectivity during individuated finger movements in humans after damage to the motor cortex or corticospinal tract
    Catherine E Lang
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Neurophysiol 91:1722-33. 2004
    ....
  15. ncbi request reprint Decoding M1 neurons during multiple finger movements
    S Ben Hamed
    Brain and Cognitive Science Dept, Meliora Hall, Univ of Rochester, Rochester, NY 14627, USA
    J Neurophysiol 98:327-33. 2007
    ..The remarkably small number of neurons needed to decode a relatively large repertoire of movements involving either one or two effectors is encouraging for the development of neural prosthetics that will control hand movements...
  16. ncbi request reprint Multiple fragment statistical analysis of post-spike effects in spike-triggered averages of rectified EMG
    A V Poliakov
    Department of Neurology, Rochester, NY 14642, USA
    J Neurosci Methods 79:143-50. 1998
    ..MFSA could be implemented for statistical analysis of other waveforms averaged, such as evoked potentials, movement-related cortical potentials, or event-related desychronizations...
  17. ncbi request reprint Rapid changes in throughput from single motor cortex neurons to muscle activity
    Adam G Davidson
    Departments of Neurology and Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Science 318:1934-7. 2007
    ....
  18. pmc Comparing effects in spike-triggered averages of rectified EMG across different behaviors
    Adam G Davidson
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Neurosci Methods 163:283-94. 2007
    ..The multiple fragment approach provides a sensitive means of identifying significant changes in SpikeTA effects...
  19. ncbi request reprint Short-term synchronization between motor units in different functional subdivisions of the human flexor digitorum profundus muscle
    Karen T Reilly
    Department of Neurobiology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 673, Rochester, NY 14642, USA
    J Neurophysiol 92:734-42. 2004
    ....
  20. ncbi request reprint Constraints on somatotopic organization in the primary motor cortex
    M H Schieber
    Department of Neurology, The Center for Visual Science, University of Rochester School of Medicine, Rochester, New York 14642, USA
    J Neurophysiol 86:2125-43. 2001
    ..I conclude with speculations on what the constrained somatotopy of M1 might tell us about its contribution to control of movement...
  21. doi request reprint An information transmission measure for the analysis of effective connectivity among cortical neurons
    Andrew J Law
    Biomedical Engineering Department at the University of Rochester, Rochester, NY, USA
    Conf Proc IEEE Eng Med Biol Soc 2010:3293-6. 2010
    ..For experimentally recorded data, where ground truth is unavailable, the proposed method also yields a more plausible effective connectivity structure than transfer entropy...
  22. ncbi request reprint Bilateral spike-triggered average effects in arm and shoulder muscles from the monkey pontomedullary reticular formation
    Adam G Davidson
    Neuroscience Graduate Studies Program, The Ohio State University, Columbus, Ohio 43210, USA
    J Neurosci 27:8053-8. 2007
    ..Spike- and stimulus-triggered averaging effects obtained from the same recording site were similar. These findings indicate that single PMRF neurons can directly influence movements of both upper limbs...
  23. ncbi request reprint Differential impairment of individuated finger movements in humans after damage to the motor cortex or the corticospinal tract
    Catherine E Lang
    Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Neurophysiol 90:1160-70. 2003
    ....
  24. ncbi request reprint Serial correlation in lateralized choices of hand and target
    Daeyeol Lee
    Department of Brain and Cognitive Sciences, Center for Visual Science, University of Rochester, Rochester, NY 14642, USA
    Exp Brain Res 174:499-509. 2006
    ....
  25. ncbi request reprint Incomplete functional subdivision of the human multitendoned finger muscle flexor digitorum profundus: an electromyographic study
    Karen T Reilly
    Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Neurophysiol 90:2560-70. 2003
    ....
  26. ncbi request reprint Interactions between lateralized choices of hand and target
    Jennifer Gardinier
    Department of Neurology, and the Brain Injury Rehabilitation Program at St Mary s Hospital, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Exp Brain Res 170:149-59. 2006
    ..We conclude that when lateralized targets are equivalent, lateralized choices are biased primarily by hand preference and secondarily by a preference to retrieve a target ipsilateral to the preferred hand...
  27. ncbi request reprint Human finger independence: limitations due to passive mechanical coupling versus active neuromuscular control
    Catherine E Lang
    Department of Neurology, University of Rochester School of Medicine and Dentistry, St Mary s Hospital, Rochester, New York 14642, USA
    J Neurophysiol 92:2802-10. 2004
    ..For the movement conditions tested here, mechanical coupling between the fingers appears to be a major factor limiting the complete independence of finger movement...
  28. ncbi request reprint Persistent hand motor commands in the amputees' brain
    Karen T Reilly
    Institut des Sciences Cognitives, Bron, France
    Brain 129:2211-23. 2006
    ....
  29. pmc Asynchronous decoding of dexterous finger movements using M1 neurons
    Vikram Aggarwal
    Department of Engineering, Johns Hopkins University, Baltimore, MD 21205, USA
    IEEE Trans Neural Syst Rehabil Eng 16:3-14. 2008
    ..This work takes an important step towards the development of a BMI for direct neural control of a state-of-the-art, multifingered hand prosthesis...
  30. pmc Decoding individuated finger movements using volume-constrained neuronal ensembles in the M1 hand area
    Soumyadipta Acharya
    Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA
    IEEE Trans Neural Syst Rehabil Eng 16:15-23. 2008
    ..The results suggest that a brain-machine interface (BMI) for dexterous control of individuated fingers and the wrist can be implemented using microelectrode arrays placed broadly in the M1 hand area...
  31. pmc Selectivity of voluntary finger flexion during ischemic nerve block of the hand
    Karen T Reilly
    Center for Cognitive Neuroscience, CNRS, 67 Boulevard Pinel, Bron, 69675, France
    Exp Brain Res 188:385-97. 2008
    ..Our observations indicate that during ischemic nerve block reorganization does not eliminate or degrade motor representations of the temporarily deafferented and paralyzed fingers...

Research Grants18

  1. Variation in Throughput from Single Motor Cortex Neurons to Muscles
    Marc H Schieber; Fiscal Year: 2010
    ....
  2. CRCNS: Dimensionality Reduction in Cortico-Muscular Control of the Hand
    Marc Schieber; Fiscal Year: 2009
    ..The co-PIs also will coordinate an innovative inter-institutional graduate level course. ..
  3. CORTICAL ACTIVITY DURING INDIVIDUATED MOVEMENTS
    Marc Schieber; Fiscal Year: 2007
    ..or task time periods? 3) Do patterns of synchrony change when a fully trained subject practices a novel movement? 4) Does synchrony occur predominantly in corticospinal or non-corticospinal primary motor cortex neurons? ..
  4. NEURONAL POPULATIONS PARTICIPATING IN MOTORIC CHOICES
    Marc Schieber; Fiscal Year: 2004
    ..inactivation or microstimulation of the PMv, SMA, and striatum bias motoric choices? (4) How do the partially overlapping cortico-striatal projections from the PMv and SMA correlate with striatal regions participating in motoric choices? ..
  5. CORTICAL ACTIVITY DURING INDIVIDUATED MOVEMENT
    Marc Schieber; Fiscal Year: 2002
    ..Finally, we will map M1 repeatedly during motor skill learning to determine (Aim 4) whether any spatial segregation diminishes as the M1 territories that provide output to trained muscles progressively enlarge and increasingly overlap. ..
  6. CRCNS: Dimensionality Reduction in Cortico-Muscular Control of the Hand
    NITISH VYOMESH THAKOR; Fiscal Year: 2010
    ..The co-PIs also will coordinate an innovative inter-institutional graduate level course. ..