Research Topics
| M H SchieberSummaryAffiliation: University of Rochester Country: USA Publications
Research Grants
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Detail Information
Publications
Mirror neurons: reflecting on the motor cortex and spinal cordMarc H Schieber
Department of Neurology, University of Rochester, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA Electronic address
Curr Biol 23:R151-2. 2013....
Dissociating motor cortex from the motorMarc H Schieber
Department of Neurology, University of Rochester, 601 Elmwood Avenue, Box 673, Rochester, NY 14642, USA
J Physiol 589:5613-24. 2011..The natural ability of motor cortex neurons under voluntarily control to become dissociated from bodily movement may underlie the utility of this cortical area for controlling brain-computer interfaces...- Selective activation of human finger muscles after stroke or amputationMarc H Schieber
Department of Neurology, University of Rochester, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
Adv Exp Med Biol 629:559-75. 2009..We infer that voluntary motor output patterns that normally control finger movements after amputation may become diverted to remaining proximal muscles... 
Partial reconstruction of muscle activity from a pruned network of diverse motor cortex neuronsMarc H Schieber
Department of Neurology, Neurobiology and Anatomy, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
J Neurophysiol 97:70-82. 2007....- A spectrum from pure post-spike effects to synchrony effects in spike-triggered averages of electromyographic activity during skilled finger movementsMarc H Schieber
University of Rochester Medical Center, Dept of Neurology, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
J Neurophysiol 94:3325-41. 2005.... - Hand function: peripheral and central constraints on performanceMarc H Schieber
Department of Neurology, University of Rochester Medical Center, 601 Elmwood Ave, Box 673, Rochester, NY 14642, USA
J Appl Physiol 96:2293-300. 2004..We review this evidence, with a particular emphasis on how these constraints extend through the neuromuscular system from the behavioral aspects of finger movements and forces to the control of the hand from the motor cortex... - Motor control: basic units of cortical output?Marc H Schieber
University of Rochester Medical Center, Department of Neurology, 601 Elmwood Avenue, Rochester, New York 14642, USA
Curr Biol 14:R353-4. 2004..Observing movement evoked by stimulating a single cortical neuron has proven technically impossible - until now. A new study using intracellular stimulation has revealed that the basic unit of cortical output is not necessarily basic... - Motor cortex and the distributed anatomy of finger movementsMarc H Schieber
Department of Neurology, University of Rochester School of Medicine and Dentistry Rochester, New York 14642, USA
Adv Exp Med Biol 508:411-6. 2002..Distinct functional groups of M1 neurones that might control particular finger movements were identified inconsistently. We therefore hypothesize that M1 neurones are a very diverse network controlling finger movements... - Primary motor cortex reorganization in a long-term monkey amputeeM H Schieber
Department of Neurology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
Somatosens Mot Res 14:157-67. 1997.... - Somatotopic gradients in the distributed organization of the human primary motor cortex hand area: evidence from small infarctsM H Schieber
Department of Neurology, Center for Visual Science, and the Brain Injury Rehabilitation Program at St Mary s Hospital, University of Rochester School of Medicine and Dentistry, New York 14642, USA
Exp Brain Res 128:139-48. 1999.... - Inactivation of the ventral premotor cortex biases the laterality of motoric choicesM H Schieber
Department of Neurology, University of Rochester Medical Center, NY 14642, USA
Exp Brain Res 130:497-507. 2000.... - Tension distribution to the five digits of the hand by neuromuscular compartments in the macaque flexor digitorum profundusM H Schieber
Departments of Neurology and of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
J Neurosci 21:2150-8. 2001..We conclude that the macaque FDP consists of four neuromuscular compartments, each of which provides a distinct distribution of tension to multiple digits... - Training and synchrony in the motor systemMarc H Schieber
Department of Neurology, The Center for Visual Science, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
J Neurosci 22:5277-81. 2002..Synchronization among neurons with relatively direct connections to spinal alpha-motoneuron pools, including motor cortex neurons, may increase as a repertoire of skilled movements is acquired and practiced during long-term training... - Reduced muscle selectivity during individuated finger movements in humans after damage to the motor cortex or corticospinal tractCatherine E Lang
Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
J Neurophysiol 91:1722-33. 2004.... - Decoding M1 neurons during multiple finger movementsS Ben Hamed
Brain and Cognitive Science Dept, Meliora Hall, Univ of Rochester, Rochester, NY 14627, USA
J Neurophysiol 98:327-33. 2007..The remarkably small number of neurons needed to decode a relatively large repertoire of movements involving either one or two effectors is encouraging for the development of neural prosthetics that will control hand movements... - Multiple fragment statistical analysis of post-spike effects in spike-triggered averages of rectified EMGA V Poliakov
Department of Neurology, Rochester, NY 14642, USA
J Neurosci Methods 79:143-50. 1998..MFSA could be implemented for statistical analysis of other waveforms averaged, such as evoked potentials, movement-related cortical potentials, or event-related desychronizations... - Rapid changes in throughput from single motor cortex neurons to muscle activityAdam G Davidson
Departments of Neurology and Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Science 318:1934-7. 2007.... - Comparing effects in spike-triggered averages of rectified EMG across different behaviorsAdam G Davidson
Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
J Neurosci Methods 163:283-94. 2007..The multiple fragment approach provides a sensitive means of identifying significant changes in SpikeTA effects... - Short-term synchronization between motor units in different functional subdivisions of the human flexor digitorum profundus muscleKaren T Reilly
Department of Neurobiology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 673, Rochester, NY 14642, USA
J Neurophysiol 92:734-42. 2004.... - Constraints on somatotopic organization in the primary motor cortexM H Schieber
Department of Neurology, The Center for Visual Science, University of Rochester School of Medicine, Rochester, New York 14642, USA
J Neurophysiol 86:2125-43. 2001..I conclude with speculations on what the constrained somatotopy of M1 might tell us about its contribution to control of movement... - An information transmission measure for the analysis of effective connectivity among cortical neuronsAndrew J Law
Biomedical Engineering Department at the University of Rochester, Rochester, NY, USA
Conf Proc IEEE Eng Med Biol Soc 2010:3293-6. 2010..For experimentally recorded data, where ground truth is unavailable, the proposed method also yields a more plausible effective connectivity structure than transfer entropy... - Bilateral spike-triggered average effects in arm and shoulder muscles from the monkey pontomedullary reticular formationAdam G Davidson
Neuroscience Graduate Studies Program, The Ohio State University, Columbus, Ohio 43210, USA
J Neurosci 27:8053-8. 2007..Spike- and stimulus-triggered averaging effects obtained from the same recording site were similar. These findings indicate that single PMRF neurons can directly influence movements of both upper limbs... - Differential impairment of individuated finger movements in humans after damage to the motor cortex or the corticospinal tractCatherine E Lang
Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
J Neurophysiol 90:1160-70. 2003.... - Serial correlation in lateralized choices of hand and targetDaeyeol Lee
Department of Brain and Cognitive Sciences, Center for Visual Science, University of Rochester, Rochester, NY 14642, USA
Exp Brain Res 174:499-509. 2006.... - Incomplete functional subdivision of the human multitendoned finger muscle flexor digitorum profundus: an electromyographic studyKaren T Reilly
Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
J Neurophysiol 90:2560-70. 2003.... - Interactions between lateralized choices of hand and targetJennifer Gardinier
Department of Neurology, and the Brain Injury Rehabilitation Program at St. Mary's Hospital, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Exp Brain Res 170:149-59. 2006..We conclude that when lateralized targets are equivalent, lateralized choices are biased primarily by hand preference and secondarily by a preference to retrieve a target ipsilateral to the preferred hand... - Human finger independence: limitations due to passive mechanical coupling versus active neuromuscular controlCatherine E Lang
Department of Neurology, University of Rochester School of Medicine and Dentistry, St Mary s Hospital, Rochester, New York 14642, USA
J Neurophysiol 92:2802-10. 2004..For the movement conditions tested here, mechanical coupling between the fingers appears to be a major factor limiting the complete independence of finger movement... - Persistent hand motor commands in the amputees' brainKaren T Reilly
Institut des Sciences Cognitives, Bron, France
Brain 129:2211-23. 2006.... - Asynchronous decoding of dexterous finger movements using M1 neuronsVikram Aggarwal
Department of Engineering, Johns Hopkins University, Baltimore, MD 21205, USA
IEEE Trans Neural Syst Rehabil Eng 16:3-14. 2008..This work takes an important step towards the development of a BMI for direct neural control of a state-of-the-art, multifingered hand prosthesis... - Decoding individuated finger movements using volume-constrained neuronal ensembles in the M1 hand areaSoumyadipta Acharya
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA
IEEE Trans Neural Syst Rehabil Eng 16:15-23. 2008..The results suggest that a brain-machine interface (BMI) for dexterous control of individuated fingers and the wrist can be implemented using microelectrode arrays placed broadly in the M1 hand area... - Selectivity of voluntary finger flexion during ischemic nerve block of the handKaren T Reilly
Center for Cognitive Neuroscience, CNRS, 67 Boulevard Pinel, Bron, 69675, France
Exp Brain Res 188:385-97. 2008..Our observations indicate that during ischemic nerve block reorganization does not eliminate or degrade motor representations of the temporarily deafferented and paralyzed fingers...
Research Grants
- Variation in Throughput from Single Motor Cortex Neurons to MusclesMarc H Schieber; Fiscal Year: 2010....
- CRCNS: Dimensionality Reduction in Cortico-Muscular Control of the HandMarc Schieber; Fiscal Year: 2009..The co-PIs also will coordinate an innovative inter-institutional graduate level course. ..
- CORTICAL ACTIVITY DURING INDIVIDUATED MOVEMENTSMarc Schieber; Fiscal Year: 2007..or task time periods? 3) Do patterns of synchrony change when a fully trained subject practices a novel movement? 4) Does synchrony occur predominantly in corticospinal or non-corticospinal primary motor cortex neurons? ..
- NEURONAL POPULATIONS PARTICIPATING IN MOTORIC CHOICESMarc Schieber; Fiscal Year: 2004..inactivation or microstimulation of the PMv, SMA, and striatum bias motoric choices? (4) How do the partially overlapping cortico-striatal projections from the PMv and SMA correlate with striatal regions participating in motoric choices? ..
- CORTICAL ACTIVITY DURING INDIVIDUATED MOVEMENTMarc Schieber; Fiscal Year: 2002..Finally, we will map M1 repeatedly during motor skill learning to determine (Aim 4) whether any spatial segregation diminishes as the M1 territories that provide output to trained muscles progressively enlarge and increasingly overlap. ..
- CRCNS: Dimensionality Reduction in Cortico-Muscular Control of the HandNITISH VYOMESH THAKOR; Fiscal Year: 2010..The co-PIs also will coordinate an innovative inter-institutional graduate level course. ..