H Schelleman

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Anti-infectives and the risk of severe hypoglycemia in users of glipizide or glyburide
    H Schelleman
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Center for Clinical Epidemiology and Biostatistics, Philadelphia, Pennsylvania, USA
    Clin Pharmacol Ther 88:214-22. 2010
  2. pmc Antidepressant-warfarin interaction and associated gastrointestinal bleeding risk in a case-control study
    Hedi Schelleman
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e21447. 2011
  3. pmc Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk
    Hedi Schelleman
    Center for Clinical Epidemiology and Biostatistics and Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, USA
    Am J Med 123:151-7. 2010
  4. doi Ethnic differences in warfarin maintenance dose requirement and its relationship with genetics
    Hedi Schelleman
    Center for Clinical Epidemiology and Biostatistics, and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, 826 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    Pharmacogenomics 9:1331-46. 2008
  5. pmc Warfarin with fluoroquinolones, sulfonamides, or azole antifungals: interactions and the risk of hospitalization for gastrointestinal bleeding
    H Schelleman
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Clin Pharmacol Ther 84:581-8. 2008
  6. pmc Dosing algorithms to predict warfarin maintenance dose in Caucasians and African Americans
    H Schelleman
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Clin Pharmacol Ther 84:332-9. 2008
  7. ncbi Warfarin response and vitamin K epoxide reductase complex 1 in African Americans and Caucasians
    H Schelleman
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, and Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA
    Clin Pharmacol Ther 81:742-7. 2007
  8. pmc Pharmacogenetic interactions of three candidate gene polymorphisms with ACE-inhibitors or beta-blockers and the risk of atherosclerosis
    H Schelleman
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    Br J Clin Pharmacol 64:57-66. 2007
  9. ncbi Diuretic-gene interaction and the risk of myocardial infarction and stroke
    H Schelleman
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Pharmacogenomics J 7:346-52. 2007
  10. ncbi Interactions between five candidate genes and antihypertensive drug therapy on blood pressure
    H Schelleman
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Pharmacogenomics J 6:22-6. 2006

Detail Information

Publications11

  1. pmc Anti-infectives and the risk of severe hypoglycemia in users of glipizide or glyburide
    H Schelleman
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Center for Clinical Epidemiology and Biostatistics, Philadelphia, Pennsylvania, USA
    Clin Pharmacol Ther 88:214-22. 2010
    ..Using cephalexin as the reference, drug-drug interactions were evident with ciprofloxacin (in glyburide users only), clarithromycin, co-trimoxazole, fluconazole, and levofloxacin...
  2. pmc Antidepressant-warfarin interaction and associated gastrointestinal bleeding risk in a case-control study
    Hedi Schelleman
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 6:e21447. 2011
    ..We sought to evaluate whether initiation of an antidepressant increases the risk of hospitalization for gastrointestinal bleeding in warfarin users...
  3. pmc Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk
    Hedi Schelleman
    Center for Clinical Epidemiology and Biostatistics and Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, USA
    Am J Med 123:151-7. 2010
    ..To evaluate whether initiation of a fibrate or statin increases the risk of hospitalization for gastrointestinal bleeding in warfarin users...
  4. doi Ethnic differences in warfarin maintenance dose requirement and its relationship with genetics
    Hedi Schelleman
    Center for Clinical Epidemiology and Biostatistics, and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, 826 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    Pharmacogenomics 9:1331-46. 2008
    ....
  5. pmc Warfarin with fluoroquinolones, sulfonamides, or azole antifungals: interactions and the risk of hospitalization for gastrointestinal bleeding
    H Schelleman
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Clin Pharmacol Ther 84:581-8. 2008
    ..Warfarin users who had received an anti-infective agent showed a substantially increased risk of GI bleeding. However, a drug-drug interaction with warfarin was evident only for co-trimoxazole and fluconazole...
  6. pmc Dosing algorithms to predict warfarin maintenance dose in Caucasians and African Americans
    H Schelleman
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Clin Pharmacol Ther 84:332-9. 2008
    ..The dosing algorithms explained <45% of the observed variability in Caucasians, and the algorithms performed only marginally better for African Americans when compared with giving 5 mg empirically...
  7. ncbi Warfarin response and vitamin K epoxide reductase complex 1 in African Americans and Caucasians
    H Schelleman
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, and Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA
    Clin Pharmacol Ther 81:742-7. 2007
    ..However, these polymorphisms may not be as useful in predicting over-anticoagulation among African Americans...
  8. pmc Pharmacogenetic interactions of three candidate gene polymorphisms with ACE-inhibitors or beta-blockers and the risk of atherosclerosis
    H Schelleman
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    Br J Clin Pharmacol 64:57-66. 2007
    ....
  9. ncbi Diuretic-gene interaction and the risk of myocardial infarction and stroke
    H Schelleman
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Pharmacogenomics J 7:346-52. 2007
    ..51; 95% CI: 0.23-1.15), whereas no interaction on the risk of stroke was found (SI: 0.84; 95% CI: 0.46-1.56)...
  10. ncbi Interactions between five candidate genes and antihypertensive drug therapy on blood pressure
    H Schelleman
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Pharmacogenomics J 6:22-6. 2006
    ..33 mmHg [95% CI: 0.14-8.54]). Thus, the mean SBP level among diuretic users may be modified by the GNB3 825C/T polymorphism...
  11. pmc Insertion/deletion polymorphism of the ACE gene and adherence to ACE inhibitors
    H Schelleman
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    Br J Clin Pharmacol 59:483-5. 2005
    ..We investigated whether the insertion/deletion (I/D) polymorphism of the ACE gene modified the adherence to ACE inhibitors as measured by the discontinuation of an ACE inhibitor, or addition of another antihypertensive drug...