Dorthe Schaue

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Cytokines in radiobiological responses: a review
    Dorthe Schaue
    David Geffen School Medicine, University of California at Los Angeles, Los Angeles, California 90095 1714, USA
    Radiat Res 178:505-23. 2012
  2. pmc Maximizing tumor immunity with fractionated radiation
    Dörthe Schaue
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, B3 109 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095 1714, USA
    Int J Radiat Oncol Biol Phys 83:1306-10. 2012
  3. ncbi request reprint Counteracting tumor radioresistance by targeting DNA repair
    Dorthe Schaue
    Department of Radiation Oncology, David Geffen School of Medicine, University of California at Los Angeles 90095 1714, USA
    Mol Cancer Ther 4:1548-50. 2005
  4. ncbi request reprint Radiation treatment of acute inflammation in mice
    Dorthe Schaue
    Gray Cancer Institute, Northwood, Middlesex, UK
    Int J Radiat Biol 81:657-67. 2005
  5. pmc Radiation enhances regulatory T cell representation
    Evelyn L Kachikwu
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1714, USA
    Int J Radiat Oncol Biol Phys 81:1128-35. 2011
  6. ncbi request reprint Immune rejection in a humanized model of murine prostate cancer
    Dorthe Schaue
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1714, USA
    Anticancer Res 30:409-14. 2010
  7. pmc Local irradiation of murine melanoma affects the development of tumour-specific immunity
    Yu Pei Liao
    Department of Radiation Oncology, University of California, Los Angeles, CA 90095 1714, USA
    Immunology 128:e797-804. 2009
  8. pmc Links between innate immunity and normal tissue radiobiology
    Dorthe Schaue
    Division of Molecular and Cellular Oncology, Department of Radiation Oncology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095 1714, USA
    Radiat Res 173:406-17. 2010
  9. pmc Regulatory T cells in radiotherapeutic responses
    Dorthe Schaue
    Division of Molecular and Cellular Oncology, Department of Radiation Oncology, David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA, USA
    Front Oncol 2:90. 2012
  10. pmc T-cell responses to survivin in cancer patients undergoing radiation therapy
    Dorthe Schaue
    Department of Radiation Oncology, University of California at Los Angeles, Los Angeles, California 90095 1714, USA
    Clin Cancer Res 14:4883-90. 2008

Detail Information

Publications12

  1. pmc Cytokines in radiobiological responses: a review
    Dorthe Schaue
    David Geffen School Medicine, University of California at Los Angeles, Los Angeles, California 90095 1714, USA
    Radiat Res 178:505-23. 2012
    ..Therapeutic intervention is made difficult by such complexity; but the potential prize is great...
  2. pmc Maximizing tumor immunity with fractionated radiation
    Dörthe Schaue
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, B3 109 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095 1714, USA
    Int J Radiat Oncol Biol Phys 83:1306-10. 2012
    ..Here we ask how radiation dose and fraction size affect antitumor immunity, the suppression thereof, and how this might relate to tumor control...
  3. ncbi request reprint Counteracting tumor radioresistance by targeting DNA repair
    Dorthe Schaue
    Department of Radiation Oncology, David Geffen School of Medicine, University of California at Los Angeles 90095 1714, USA
    Mol Cancer Ther 4:1548-50. 2005
  4. ncbi request reprint Radiation treatment of acute inflammation in mice
    Dorthe Schaue
    Gray Cancer Institute, Northwood, Middlesex, UK
    Int J Radiat Biol 81:657-67. 2005
    ..Here we report findings on radiation treatment of acute inflammation using a murine carrageenin air pouch model...
  5. pmc Radiation enhances regulatory T cell representation
    Evelyn L Kachikwu
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1714, USA
    Int J Radiat Oncol Biol Phys 81:1128-35. 2011
    ..This study was undertaken to evaluate the impact of radiation therapy (RT) on immunosuppressive T regulatory (Treg) cells...
  6. ncbi request reprint Immune rejection in a humanized model of murine prostate cancer
    Dorthe Schaue
    Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1714, USA
    Anticancer Res 30:409-14. 2010
    ..Background/Aim: We attempted to develop a humanized mouse model for prostate cancer to study immune recognition and responses to human prostate-tumor antigens in mice...
  7. pmc Local irradiation of murine melanoma affects the development of tumour-specific immunity
    Yu Pei Liao
    Department of Radiation Oncology, University of California, Los Angeles, CA 90095 1714, USA
    Immunology 128:e797-804. 2009
    ....
  8. pmc Links between innate immunity and normal tissue radiobiology
    Dorthe Schaue
    Division of Molecular and Cellular Oncology, Department of Radiation Oncology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095 1714, USA
    Radiat Res 173:406-17. 2010
    ..Importantly, these canonical pathways provide targets for interventions aimed at modifying normal tissue radiation responses. In this review, we examine areas of intersection between innate immunity and normal tissue radiobiology...
  9. pmc Regulatory T cells in radiotherapeutic responses
    Dorthe Schaue
    Division of Molecular and Cellular Oncology, Department of Radiation Oncology, David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA, USA
    Front Oncol 2:90. 2012
    ....
  10. pmc T-cell responses to survivin in cancer patients undergoing radiation therapy
    Dorthe Schaue
    Department of Radiation Oncology, University of California at Los Angeles, Los Angeles, California 90095 1714, USA
    Clin Cancer Res 14:4883-90. 2008
    ..The goal of this study was to determine if radiation therapy (RT) of human cancer enhances or diminishes tumor-specific T-cell reactivity. This is important if immunotherapy is to be harnessed to improve the outcome of cancer radiotherapy...
  11. pmc T lymphocytes and normal tissue responses to radiation
    Dorthe Schaue
    Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles Los Angeles, CA, USA
    Front Oncol 2:119. 2012
    ..This review will discuss the yin and yang of T cell responses within the context of radiation exposures, how they might drive or protect against normal tissue side effects and what we may be able do about it...
  12. ncbi request reprint Modification of the tumor microenvironment to enhance immunity
    Yu Pei Liao
    Department of Radiation Oncology, UCLA David Geffen School of Medicine, Los Angeles, CA 90095 1714, USA
    Front Biosci 12:3576-600. 2007
    ..The challenge is how to design combination therapies that modify the tumor microenvironment so as to promote immunity and better combat both local and systemic disease...