C L Schardl

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. pmc Tall fescue endophyte effects on tolerance to water-deficit stress
    Padmaja Nagabhyru
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546 0312, USA
    BMC Plant Biol 13:127. 2013
  2. pmc The epichloae: alkaloid diversity and roles in symbiosis with grasses
    Christopher L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546 0312, USA
    Curr Opin Plant Biol 16:480-8. 2013
  3. pmc Currencies of mutualisms: sources of alkaloid genes in vertically transmitted epichloae
    Christopher L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546, USA
    Toxins (Basel) 5:1064-88. 2013
  4. pmc Plant-symbiotic fungi as chemical engineers: multi-genome analysis of the clavicipitaceae reveals dynamics of alkaloid loci
    Christopher L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA
    PLoS Genet 9:e1003323. 2013
  5. ncbi request reprint Interspecific hybridization in plant-associated fungi and oomycetes: a review
    C L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky 40546 0091, USA
    Mol Ecol 12:2861-73. 2003
  6. ncbi request reprint Symbioses of grasses with seedborne fungal endophytes
    Christopher L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky 40546 0312, USA
    Annu Rev Plant Biol 55:315-40. 2004
  7. doi request reprint A novel test for host-symbiont codivergence indicates ancient origin of fungal endophytes in grasses
    C L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546 0312, USA
    Syst Biol 57:483-98. 2008
  8. ncbi request reprint Epichloë festucae and related mutualistic symbionts of grasses
    C L Schardl
    Department of Plant Pathology, University of Kentucky, S-305 Agricultural Sciences Building N, Lexington, KY 40546-0091, USA
    Fungal Genet Biol 33:69-82. 2001
  9. ncbi request reprint Production of loline alkaloids by the grass endophyte, Neotyphodium uncinatum, in defined media
    J D Blankenship
    Department of Plant Pathology, University of Kentucky, Lexington 40546-0091, USA
    Phytochemistry 58:395-401. 2001
  10. pmc Regulation of a chemical defense against herbivory produced by symbiotic fungi in grass plants
    Dong Xiu Zhang
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky 40146 0312, USA
    Plant Physiol 150:1072-82. 2009

Collaborators

Detail Information

Publications24

  1. pmc Tall fescue endophyte effects on tolerance to water-deficit stress
    Padmaja Nagabhyru
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546 0312, USA
    BMC Plant Biol 13:127. 2013
    ..In time course studies on the E+ and E- clones, water was withheld from 0 to 5 days, during which levels of free sugars, sugar alcohols, and amino acids were determined, as were levels of some major fungal metabolites...
  2. pmc The epichloae: alkaloid diversity and roles in symbiosis with grasses
    Christopher L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546 0312, USA
    Curr Opin Plant Biol 16:480-8. 2013
    ..We suggest that alkaloid diversification is selected especially in the vertically transmissible epichloae. ..
  3. pmc Currencies of mutualisms: sources of alkaloid genes in vertically transmitted epichloae
    Christopher L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546, USA
    Toxins (Basel) 5:1064-88. 2013
    ..Also, in those hybrids that had multiple EAS, IDT or LOL clusters, one cluster lacked some genes, usually for late pathway steps. Possible implications of these findings for the alkaloid profiles and endophyte ecology are discussed...
  4. pmc Plant-symbiotic fungi as chemical engineers: multi-genome analysis of the clavicipitaceae reveals dynamics of alkaloid loci
    Christopher L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky, USA
    PLoS Genet 9:e1003323. 2013
    ..We suggest that such selection is related to the variable life histories of the epichloae, their protective roles as symbionts, and their associations with the highly speciose and ecologically diverse cool-season grasses...
  5. ncbi request reprint Interspecific hybridization in plant-associated fungi and oomycetes: a review
    C L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky 40546 0091, USA
    Mol Ecol 12:2861-73. 2003
    ..Hybrid mutualists may also be better adapted to new hosts and can provide greater or more diverse benefits to host plants...
  6. ncbi request reprint Symbioses of grasses with seedborne fungal endophytes
    Christopher L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky 40546 0312, USA
    Annu Rev Plant Biol 55:315-40. 2004
    ..coenophialum symbioses, the plant may depend on the endophyte under many natural conditions. Recent advances in endophyte molecular biology promise to shed light on the mechanisms of the symbioses and host benefits...
  7. doi request reprint A novel test for host-symbiont codivergence indicates ancient origin of fungal endophytes in grasses
    C L Schardl
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546 0312, USA
    Syst Biol 57:483-98. 2008
    ..We also applied our method to the well-known gopher-louse data set...
  8. ncbi request reprint Epichloë festucae and related mutualistic symbionts of grasses
    C L Schardl
    Department of Plant Pathology, University of Kentucky, S-305 Agricultural Sciences Building N, Lexington, KY 40546-0091, USA
    Fungal Genet Biol 33:69-82. 2001
    ..festucae and host plants ensure an exquisitely balanced interaction to the mutual benefit of both partners. Several mutualistic Neotyphodium species are hybrids between E. festucae and other endophyte species...
  9. ncbi request reprint Production of loline alkaloids by the grass endophyte, Neotyphodium uncinatum, in defined media
    J D Blankenship
    Department of Plant Pathology, University of Kentucky, Lexington 40546-0091, USA
    Phytochemistry 58:395-401. 2001
    ..7 mM sucrose and 30 mM ornithine. The alkaloid production rate peaked after the onset of stationary phase, as is common for secondary metabolism in other microbes...
  10. pmc Regulation of a chemical defense against herbivory produced by symbiotic fungi in grass plants
    Dong Xiu Zhang
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky 40146 0312, USA
    Plant Physiol 150:1072-82. 2009
    ..As a result, lolines maximally protect young host tissues in a fashion similar to endogenous plant metabolites that conform to optimal defense theory...
  11. ncbi request reprint The Claviceps purpurea gene encoding dimethylallyltryptophan synthase, the committed step for ergot alkaloid biosynthesis
    H F Tsai
    Department of Plant Pathology, University of Kentucky, Lexington 40546 0091, USA
    Biochem Biophys Res Commun 216:119-25. 1995
    ..The sequence of dmaW and its cDNA indicated that it encoded a 455 amino acid polypeptide with a predicted molecular mass of 51,824 Da and a putative prenyl diphosphate binding motif...
  12. ncbi request reprint On the sequence of bond formation in loline alkaloid biosynthesis
    Jerome R Faulkner
    Department of Plant Pathology, University of Kentucky, Lexington, 40546 0312, USA
    Chembiochem 7:1078-88. 2006
    ..The incorporation of these two compounds into lolines and the lack of incorporation of several related compounds clarify the order of bond formation in loline alkaloid biosynthesis...
  13. ncbi request reprint Expressed sequence tags and genes associated with loline alkaloid expression by the fungal endophyte Neotyphodium uncinatum
    Martin J Spiering
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546 0091, USA
    Fungal Genet Biol 36:242-54. 2002
    ..These findings open up the possibility for detailed studies on genes and enzymes involved in LA production...
  14. ncbi request reprint Loline alkaloids: Currencies of mutualism
    Christopher L Schardl
    Department of Plant Pathology, 201F Plant Science Building, 1405 Veterans Drive, University of Kentucky, Lexington, KY 40546 0312, USA
    Phytochemistry 68:980-96. 2007
    ....
  15. ncbi request reprint The determinant step in ergot alkaloid biosynthesis by an endophyte of perennial ryegrass
    Jinghong Wang
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546 0312, USA
    Fungal Genet Biol 41:189-98. 2004
    ..Thus, the biosynthetic role of DMAT synthase was confirmed, and a mutant was generated for future studies of the ecological and agricultural importance of ergot alkaloids in endophytes of grasses...
  16. ncbi request reprint New neotyphodium endophyte species from the grass tribes stipeae and meliceae
    Christina D Moon
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky 40546 0312, USA
    Mycologia 99:895-905. 2007
    ..We also propose the new variety, N. gansuense var. inebrians for endophytes of A. inebrians from Xinjiang Province, which are morphologically and phylogenetically distinct from, yet clearly related to, N. gansuense from Gansu Province...
  17. pmc Gene clusters for insecticidal loline alkaloids in the grass-endophytic fungus Neotyphodium uncinatum
    Martin J Spiering
    Department of Plant Pathology, University of Kentucky, Lexington, 40546 0312, USA
    Genetics 169:1403-14. 2005
    ..The predicted LolU protein has a DNA-binding site signature, and the relationships of other lol-gene products indicate that the pathway has evolved from various different primary and secondary biosynthesis pathways...
  18. doi request reprint Coregulated expression of loline alkaloid-biosynthesis genes in Neotyphodium uncinatum cultures
    Dong Xiu Zhang
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky 40546, USA
    Fungal Genet Biol 46:517-30. 2009
    ..However, low expression of P(lolC2)uidA and P(lolA2)uidA in N. uncinatum transformants suggested induced expression of LOL genes might be subject to position effect at the LOL locus...
  19. ncbi request reprint Comparison of loline alkaloid gene clusters across fungal endophytes: predicting the co-regulatory sequence motifs and the evolutionary history
    Brandi L Kutil
    Department of Plant Pathology and Microbiology, Texas A and M University 2132, College Station, TX 77843 2132, USA
    Fungal Genet Biol 44:1002-10. 2007
    ..Thus, these data support a model of evolution in which the polymorphism in loline alkaloid production phenotypes among endophyte species is likely due to the loss of the trait over time...
  20. ncbi request reprint Origin, divergence, and phylogeny of epichloe endophytes of native Argentine grasses
    Agustina Gentile
    Laboratorio de Micologia, PRHIDEB CONICET, Depart Biodiversidad y Biología Exp, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina
    Mol Phylogenet Evol 35:196-208. 2005
    ..These results indicate that interspecific hybridization, which promotes genetic variation, was common during the evolution of the endophytes of Argentine grasses...
  21. ncbi request reprint Structural analysis of a peptide synthetase gene required for ergopeptine production in the endophytic fungus Neotyphodium lolii
    Prapassorn Damrongkool
    West Virginia University, Division of Plant and Soil Sciences, Morgantown, WV, 26506, USA
    DNA Seq 16:379-85. 2005
    ..Our results provide new information on the structure and distribution of this important peptide synthetase involved in ergot alkaloid biosynthesis...
  22. ncbi request reprint Symbiont-mediated changes in Lolium arundinaceum inducible defenses: evidence from changes in gene expression and leaf composition
    Terrence J Sullivan
    Department of Biology, Hope College, Holland, MI 49423, USA
    New Phytol 176:673-9. 2007
    ..For L. arundinaceum, N. coenophialum appears to switch its host's defensive strategy from tolerance via compensation to resistance...
  23. ncbi request reprint Using mating-type gene sequences for improved phylogenetic resolution of Collectotrichum species complexes
    Meizhu Du
    Department of Plant Pathology, University of Kentucky, Lexington, Kentucky 40546 0312, USA
    Mycologia 97:641-58. 2005
    ..Spore shape and hyphopodia shape more often were useful for this purpose...
  24. ncbi request reprint Effects of ergot alkaloids on food preference and satiety in rabbits, as assessed with gene-knockout endophytes in perennial ryegrass (Lolium perenne)
    Daniel G Panaccione
    Division of Plant and Soil Sciences, P O Box 6108, Division of Animal and Veterinary Sciences, and Department of Statistics, West Virginia University, Morgantown, West Virginia, 26506, USA
    J Agric Food Chem 54:4582-7. 2006
    ..05). The data indicate that clavines were sufficient to reduce the appeal of endophyte-infected grasses, whereas only ergovaline reduced appetite...