S L Schantz

Summary

Affiliation: University of Illinois
Country: USA

Publications

  1. pmc Lakes in crisis
    Susan L Schantz
    Environ Health Perspect 113:A148-9. 2005
  2. ncbi request reprint Developmental neurotoxicity of PCBs in humans: what do we know and where do we go from here?
    S L Schantz
    Institute for Environmental Studies, University of Illinois at Urbana Champaign 61801, USA
    Neurotoxicol Teratol 18:217-27; discussion 229-76. 1996
  3. pmc Effects of PCB exposure on neuropsychological function in children
    Susan L Schantz
    Department of Veterinary Biosciences, College of Veterinary Medicine, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    Environ Health Perspect 111:357-576. 2003
  4. pmc Cognitive effects of endocrine-disrupting chemicals in animals
    S L Schantz
    Department of Veterinary Biosciences and Neuroscience Program, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    Environ Health Perspect 109:1197-206. 2001
  5. pmc Impairments of memory and learning in older adults exposed to polychlorinated biphenyls via consumption of Great Lakes fish
    S L Schantz
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    Environ Health Perspect 109:605-11. 2001
  6. ncbi request reprint Motor function in aging Great Lakes fisheaters
    S L Schantz
    College of Veterinary Medicine, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    Environ Res 80:S46-S56. 1999
  7. ncbi request reprint Neuropsychological assessment of an aging population of Great Lakes fisheaters
    S L Schantz
    Institute for Environmental Studies, University of Illinois at Urbana Champaign 61801, USA
    Toxicol Ind Health 12:403-17. 1996
  8. ncbi request reprint Effects of gestational and lactational exposure to TCDD or coplanar PCBs on spatial learning
    S L Schantz
    Institute for Environmental Studies and Neuroscience Program, University of Illinois at Urbana Champaign, 61801, USA
    Neurotoxicol Teratol 18:305-13. 1996
  9. pmc Chronic estradiol replacement impairs performance on an operant delayed spatial alternation task in young, middle-aged, and old rats
    Victor C Wang
    Neuroscience Program and Department of Veterinary Sciences, University of Illinois at Urbana Champaign, USA
    Horm Behav 56:382-90. 2009
  10. pmc Effects of chronic estradiol treatment on delayed spatial alternation and differential reinforcement of low rates of responding
    Victor C Wang
    Neuroscience Program, University of Illinois at Urbana Champaign, Urbana, IL, USA
    Behav Neurosci 122:794-804. 2008

Collaborators

Detail Information

Publications28

  1. pmc Lakes in crisis
    Susan L Schantz
    Environ Health Perspect 113:A148-9. 2005
  2. ncbi request reprint Developmental neurotoxicity of PCBs in humans: what do we know and where do we go from here?
    S L Schantz
    Institute for Environmental Studies, University of Illinois at Urbana Champaign 61801, USA
    Neurotoxicol Teratol 18:217-27; discussion 229-76. 1996
    ..Hopefully, several new studies that are currently underway will help to resolve the uncertainties regarding the risks of perinatal PCB exposure that have been created by the conflicting results of these early studies...
  3. pmc Effects of PCB exposure on neuropsychological function in children
    Susan L Schantz
    Department of Veterinary Biosciences, College of Veterinary Medicine, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    Environ Health Perspect 111:357-576. 2003
    ..More complete information on the health effects of various congeners or congener classes would allow more informed scientific and risk assessment decisions...
  4. pmc Cognitive effects of endocrine-disrupting chemicals in animals
    S L Schantz
    Department of Veterinary Biosciences and Neuroscience Program, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    Environ Health Perspect 109:1197-206. 2001
    ....
  5. pmc Impairments of memory and learning in older adults exposed to polychlorinated biphenyls via consumption of Great Lakes fish
    S L Schantz
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    Environ Health Perspect 109:605-11. 2001
    ..These results are consistent with previous research showing an association between in utero PCB exposure and impairments of memory during infancy and childhood...
  6. ncbi request reprint Motor function in aging Great Lakes fisheaters
    S L Schantz
    College of Veterinary Medicine, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    Environ Res 80:S46-S56. 1999
    ..46). These findings suggest that PCB/DDE exposure from Great Lakes fish has not significantly impaired hand steadiness or visual-motor coordination in this sample of older adults...
  7. ncbi request reprint Neuropsychological assessment of an aging population of Great Lakes fisheaters
    S L Schantz
    Institute for Environmental Studies, University of Illinois at Urbana Champaign 61801, USA
    Toxicol Ind Health 12:403-17. 1996
    ..DDE concentrations predict the degree of behavioral dysfunction? and 3) If PCB exposure is related to behavioral outcomes, which class of PCB congeners, ortho-substituted or coplanar, are responsible for the cognitive and motor deficits?..
  8. ncbi request reprint Effects of gestational and lactational exposure to TCDD or coplanar PCBs on spatial learning
    S L Schantz
    Institute for Environmental Studies and Neuroscience Program, University of Illinois at Urbana Champaign, 61801, USA
    Neurotoxicol Teratol 18:305-13. 1996
    ..Together these findings suggest that coplanar and ortho-substituted PCBs may have different mechanisms of action on the CNS...
  9. pmc Chronic estradiol replacement impairs performance on an operant delayed spatial alternation task in young, middle-aged, and old rats
    Victor C Wang
    Neuroscience Program and Department of Veterinary Sciences, University of Illinois at Urbana Champaign, USA
    Horm Behav 56:382-90. 2009
    ....
  10. pmc Effects of chronic estradiol treatment on delayed spatial alternation and differential reinforcement of low rates of responding
    Victor C Wang
    Neuroscience Program, University of Illinois at Urbana Champaign, Urbana, IL, USA
    Behav Neurosci 122:794-804. 2008
    ..These data suggest that chronic estrogen exposure may impair rats' abilities on measures of executive function including working memory and response inhibition...
  11. ncbi request reprint Alterations in DRH and DRL performance in rats developmentally exposed to an environmental PCB mixture
    Helen J K Sable
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, IL 61802 USA
    Neurotoxicol Teratol 28:548-56. 2006
    ..Overall, exposure to this PCB mixture resulted in increased responding which was suggestive of a deficit in inhibitory control...
  12. ncbi request reprint Effects of perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on spatial and visual reversal learning in rats
    John J Widholm
    Department of Veterinary Biosciences, College of Veterinary Medicine, University of Illinois at Urbana Champaign, 2001 South Lincoln Avenue, Urbana, IL 61802, USA
    Neurotoxicol Teratol 25:459-71. 2003
    ....
  13. ncbi request reprint Tetrachlorodibenzo-p-dioxin exposure alters radial arm maze performance and hippocampal morphology in female AhR mice
    B E Powers
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Genes Brain Behav 4:51-9. 2005
    ..It is hypothesized that the effect of TCDD exposure is AhR dependent and that TCDD may alter GABAergic activity in the hippocampus of female mice during development...
  14. ncbi request reprint Spatial reversal learning in Aroclor 1254-exposed rats: sex-specific deficits in associative ability and inhibitory control
    J J Widholm
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    Toxicol Appl Pharmacol 174:188-98. 2001
    ..e., associative deficit). These data provide new insights into the underlying behavioral mechanisms that may be responsible for the spatial learning deficits observed in PCB-exposed rodents and monkeys...
  15. pmc Impact of dietary genistein and aging on executive function in rats
    Steven L Neese
    Department of Veterinary Sciences, University of Illinois at Urbana Champaign, 2001 S Lincoln Avenue, Urbana, IL 61802, USA
    Neurotoxicol Teratol 32:200-11. 2010
    ....
  16. ncbi request reprint Motor impairment in rats exposed to PCBs and methylmercury during early development
    Cindy S Roegge
    Neuroscience Program, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
    Toxicol Sci 77:315-24. 2004
    ..Our results demonstrate that the possibility of additive neurotoxic effects of PCBs and MeHg needs to be seriously considered...
  17. ncbi request reprint Auditory deficits in rats exposed to an environmental PCB mixture during development
    Brian E Powers
    Neuroscience Program, University of Illinois at Urbana Champaign, Urbana, Illinois, 61802, USA
    Toxicol Sci 89:415-22. 2006
    ..Developmental exposure to PCBs may also result in subtle auditory impairments in humans, and if so, this may contribute to some of the cognitive deficits that have been observed in epidemiological studies...
  18. pmc Developmental exposure to PCBs and/or MeHg: effects on a differential reinforcement of low rates (DRL) operant task before and after amphetamine drug challenge
    Helen J K Sable
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Neurotoxicol Teratol 31:149-58. 2009
    ....
  19. ncbi request reprint Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats
    Clinton D Allred
    Department of Food Science and Human Nutrition, University of Illinois, Urbana, IL 61801, USA
    Carcinogenesis 25:211-8. 2004
    ..The data suggest that in an endogenous estrogen environment similar to that of a postmenopausal woman, dietary genistein can stimulate the growth of a mammary carcinogen MNU-induced estrogen-dependent mammary tumors...
  20. pmc Contaminant profiles in Southeast Asian immigrants consuming fish from polluted waters in northeastern Wisconsin
    Susan L Schantz
    Department of Veterinary Biosciences, College of Veterinary Medicine, University of Illinois at Urbana Champaign, 2001 South Lincoln Avenue, Urbana, IL 61802, USA
    Environ Res 110:33-9. 2010
    ..The pattern of exposure is somewhat different than patterns in other fish-eating populations, possibly due to use of Aroclor 1242 by the paper industry in this region...
  21. pmc Developmental exposure to PCBs, MeHg, or both: long-term effects on auditory function
    Brian E Powers
    Neuroscience Program, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    Environ Health Perspect 117:1101-7. 2009
    ..However, little is known about the effects of combined exposure to PCBs and MeHg on auditory function...
  22. ncbi request reprint Perinatal exposure to Aroclor 1254 impairs distortion product otoacoustic emissions (DPOAEs) in rats
    Robert E Lasky
    Center for Clinical Research and Evidence Based Medicine, University of Texas Health Science Center at Houston Medical School, 6431 Fannin, MSB 2 104, Houston, Texas 77030 1503, USA
    Toxicol Sci 68:458-64. 2002
    ..In contrast, ABR latencies and amplitudes were not altered by A1254 exposure. These findings provide the first functional evidence supporting a cochlear site of damage in PCB-induced hearing loss...
  23. pmc A longitudinal examination of factors related to changes in serum polychlorinated biphenyl levels
    P Grace Tee
    School of Public Health, University of Texas, Houston, Texas, USA
    Environ Health Perspect 111:702-7. 2003
    ..PCB levels were particularly elevated for males who were classified as fisheaters in 1980, which may reflect higher levels of sport-caught fish consumption compared with female fisheaters...
  24. ncbi request reprint Motor function following developmental exposure to PCBS and/or MEHG
    Cindy S Roegge
    Psychiatry Department, Duke University Medical Center, Box 3415 Bell Building, Durham, NC 27710, USA
    Neurotoxicol Teratol 28:260-77. 2006
    ..There is need for a better understanding of the interactive effects of PCBs and MeHg, especially in regard to motor function...
  25. ncbi request reprint Purkinje cell and cerebellar effects following developmental exposure to PCBs and/or MeHg
    Cindy S Roegge
    Psychiatry Department, Duke University Medical Center, Durham, NC 27710, USA
    Neurotoxicol Teratol 28:74-85. 2006
    ....
  26. ncbi request reprint Formulation and characterization of an experimental PCB mixture designed to mimic human exposure from contaminated fish
    Paul J Kostyniak
    University at Buffalo, New York 14214, USA
    Toxicol Sci 88:400-11. 2005
    ..This illustrates that Aroclor mixtures are useful for formulating dosing solutions which closely approximate actual environmental exposures...
  27. ncbi request reprint Delayed spatial alternation impairments in adult rats following dietary n-6 deficiency during development
    Cindy S Roegge
    Neuroscience Program, University of Illinois at Urbana Champaign, Urbana, IL 61802, United States
    Neurotoxicol Teratol 27:485-95. 2005
    ..Thus, the observed delayed spatial alternation impairments in rats fed PO fish and fish oil are hypothesized to have resulted from the altered n-6/n-3 FA ratios...
  28. ncbi request reprint Spatial alternation deficits following developmental exposure to Aroclor 1254 and/or methylmercury in rats
    John J Widholm
    Department of Psychology, College of Charleston, Charleston, South Carolina 29424, USA
    Toxicol Sci 82:577-89. 2004
    ..The results from the current study indicate that combined exposure to PCBs and MeHg does not exacerbate the PCB- or MeHg-induced impairments on spatial alternation tasks...

Research Grants4

  1. RESEARCH TRAINING PROGRAM IN ENVIRONMENTAL TOXICOLOGY
    Susan Schantz; Fiscal Year: 2007
    ..Selection will be based on academic success, relevance of proposed research to Program goals and commitment to toxicology. This effort to recruit under-represented minorities will continue. ..
  2. PCBs, PBDEs, Hearing Loss & Attention/Impulsivity: Mechanistic Studies in Animals
    Susan Schantz; Fiscal Year: 2006
    ..As in the past, findings from these animal studies will guide the selection of outcome measures for use in the birth cohort. ..