Christine E Schaner-Tooley

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. pmc NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein
    Christine E Schaner Tooley
    Department of Microbiology, Center for Cell Signaling, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Nature 466:1125-8. 2010
  2. ncbi N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis
    Ting Chen
    Department of Microbiology, Center for Cell Signaling, University of Virginia School of Medicine University of Virginia, Charlottesville, VA 22908 0577, USA
    Nat Cell Biol 9:596-603. 2007

Research Grants

  1. Regulation of RCC1 through N-terminal serine metnylation
    CHRISTINE SCHANER TOOLEY; Fiscal Year: 2007

Collaborators

  • Ian G Macara
  • Wladek Minor
  • CHRISTINE SCHANER TOOLEY
  • Christine E Schaner Tooley
  • Donald F Hunt
  • Jeffrey Shabanowitz
  • Ting Chen
  • Michal Sabat
  • Tara L Muratore-Schroeder
  • Janusz J Petkowski
  • Jeremy L Balsbaugh
  • Tara L Muratore

Detail Information

Publications2

  1. pmc NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein
    Christine E Schaner Tooley
    Department of Microbiology, Center for Cell Signaling, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Nature 466:1125-8. 2010
    ..Knockdown of NRMT recapitulates the multi-spindle phenotype seen with methylation-defective RCC1 mutants, demonstrating the importance of alpha-N-methylation for normal bipolar spindle formation and chromosome segregation...
  2. ncbi N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis
    Ting Chen
    Department of Microbiology, Center for Cell Signaling, University of Virginia School of Medicine University of Virginia, Charlottesville, VA 22908 0577, USA
    Nat Cell Biol 9:596-603. 2007
    ..These data provide the first known function for N-terminal protein methylation...

Research Grants2

  1. Regulation of RCC1 through N-terminal serine metnylation
    CHRISTINE SCHANER TOOLEY; Fiscal Year: 2007
    ..Specific aim #2 will identify the methyltransferase responsible for the N-terminal serine methylation of RCC1. ..