W R Schafer

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Genes affecting sensitivity to serotonin in Caenorhabditis elegans
    W R Schafer
    Department of Biochemistry and Biophysics, University of California, San Francisco 94143 0554, USA
    Genetics 143:1219-30. 1996
  2. ncbi request reprint A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans
    W R Schafer
    Department of Biochemistry and Biophysics, University of California, San Francisco 94143 0554, USA
    Nature 375:73-8. 1995
  3. pmc Genes affecting the activity of nicotinic receptors involved in Caenorhabditis elegans egg-laying behavior
    J Kim
    Division of Biology, University of California, San Diego, California 92093 0349, USA
    Genetics 157:1599-610. 2001
  4. ncbi request reprint Control of alternative behavioral states by serotonin in Caenorhabditis elegans
    L E Waggoner
    Department of Biology, University of California, San Diego, La Jolla 92093, USA
    Neuron 21:203-14. 1998
  5. ncbi request reprint Serotonin modulates locomotory behavior and coordinates egg-laying and movement in Caenorhabditis elegans
    L A Hardaker
    Division of Biology, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0349, USA
    J Neurobiol 49:303-13. 2001
  6. pmc Effect of a neuropeptide gene on behavioral states in Caenorhabditis elegans egg-laying
    L E Waggoner
    Department of Biology, University of California, San Diego, California 92093 0349, USA
    Genetics 154:1181-92. 2000

Collaborators

  • J Kim
  • L E Waggoner
  • L A Hardaker
  • E Singer
  • R Kerr
  • G Zhou
  • S Golik
  • G T Zhou
  • R W Schafer

Detail Information

Publications6

  1. pmc Genes affecting sensitivity to serotonin in Caenorhabditis elegans
    W R Schafer
    Department of Biochemistry and Biophysics, University of California, San Francisco 94143 0554, USA
    Genetics 143:1219-30. 1996
    ..Thus, acetylcholine appears to negatively regulate the response to serotonin and may participate in the process of serotonin desensitization...
  2. ncbi request reprint A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans
    W R Schafer
    Department of Biochemistry and Biophysics, University of California, San Francisco 94143 0554, USA
    Nature 375:73-8. 1995
    ..We propose that adaptation to serotonin occurs through activation of an Unc-2-dependent calcium influx, which modulates the postsynaptic response to serotonin, perhaps by inhibiting the release of a potentiating neuropeptide...
  3. pmc Genes affecting the activity of nicotinic receptors involved in Caenorhabditis elegans egg-laying behavior
    J Kim
    Division of Biology, University of California, San Diego, California 92093 0349, USA
    Genetics 157:1599-610. 2001
    ....
  4. ncbi request reprint Control of alternative behavioral states by serotonin in Caenorhabditis elegans
    L E Waggoner
    Department of Biology, University of California, San Diego, La Jolla 92093, USA
    Neuron 21:203-14. 1998
    ..Genetic experiments suggest that determination of the behavioral states observed for C. elegans egg laying may be mediated through protein kinase C-dependent (PKC-dependent) modulation of voltage-gated calcium channels...
  5. ncbi request reprint Serotonin modulates locomotory behavior and coordinates egg-laying and movement in Caenorhabditis elegans
    L A Hardaker
    Division of Biology, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0349, USA
    J Neurobiol 49:303-13. 2001
    ..Thus, serotonin appears to function specifically to facilitate increased locomotion during periods of active egg-laying, and to function generally to modulate decision-making neurons that promote forward movement...
  6. pmc Effect of a neuropeptide gene on behavioral states in Caenorhabditis elegans egg-laying
    L E Waggoner
    Department of Biology, University of California, San Diego, California 92093 0349, USA
    Genetics 154:1181-92. 2000
    ..Because flp-1 is known to be expressed in interneurons that are postsynaptic to a variety of chemosensory cells, the FLP-1 peptides may function to regulate the activity of the egg-laying circuitry in response to sensory cues...