Frank Scannapieco

Summary

Affiliation: University at Buffalo
Country: USA

Publications

  1. ncbi request reprint Periodontitis and chronic kidney disease
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, Buffalo, NY, USA
    J Periodontol 79:1617-9. 2008
  2. ncbi request reprint Individuals With Chronic Obstructive Pulmonary Disease (COPD) May Be More Likely to Have More Severe Periodontal Disease Than Individuals Without COPD
    Frank A Scannapieco
    Professor and Chair, Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Foster Hall, Buffalo, NY 14214, USA, Tel 1 716 829 2854 Electronic address
    J Evid Based Dent Pract 14:79-81. 2014
  3. doi request reprint Modest reduction in risk for ventilator-associated pneumonia in critically ill patients receiving mechanical ventilation following topical oral chlorhexidine
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Foster Hall, Buffalo, New York 14214, USA
    J Evid Based Dent Pract 12:15-7. 2012
  4. ncbi request reprint Modest reduction in risk for ventilator-associated pneumonia in critically ill patients receiving mechanical ventilation following topical oral chlorhexidine
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, New York 14214, USA
    J Evid Based Dent Pract 12:103-6. 2012
  5. pmc Response of fatty acid synthesis genes to the binding of human salivary amylase by Streptococcus gordonii
    Anna E Nikitkova
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA
    Appl Environ Microbiol 78:1865-75. 2012
  6. pmc Interaction of salivary alpha-amylase and amylase-binding-protein A (AbpA) of Streptococcus gordonii with glucosyltransferase of S. gordonii and Streptococcus mutans
    Biswendu Chaudhuri
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, New York, USA
    BMC Microbiol 7:60. 2007
  7. ncbi request reprint Pneumonia in nonambulatory patients. The role of oral bacteria and oral hygiene
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, 109 Foster Hall, Buffalo, N Y 14214
    J Am Dent Assoc 137:21S-25S. 2006
  8. pmc Salivary biomarkers associated with alveolar bone loss
    F A Scannapieco
    Departments of Oral Biology, School of Dental Medicine, State University at Buffalo, Buffalo, NY 14214, USA
    Ann N Y Acad Sci 1098:496-7. 2007
  9. ncbi request reprint Systemic effects of periodontal diseases
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, 109 Foster Hall, Buffalo, NY 14214, USA
    Dent Clin North Am 49:533-50, vi. 2005
  10. doi request reprint "Does periodontal therapy reduce the risk for systemic diseases?"
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Foster Hall, Buffalo, NY 14214, USA
    Dent Clin North Am 54:163-81. 2010

Research Grants

  1. Amylase Binding Streptococci Dental Plaque and Caries
    Frank Scannapieco; Fiscal Year: 2007
  2. Amylase Binding Streptococci Dental Plaque and Caries
    Frank Scannapieco; Fiscal Year: 2006
  3. Oral Health and Ventilator Associated Pneumonia
    Frank Scannapieco; Fiscal Year: 2005
  4. AMYLASE BINDING STREPTOCOCCI, DENTAL PLAQUE AND CARIES
    Frank Scannapieco; Fiscal Year: 2000
  5. Amylase Binding Streptococci Dental Plaque and Caries
    Frank Scannapieco; Fiscal Year: 2004
  6. Oral Health and Ventilator Associated Pneumonia
    Frank Scannapieco; Fiscal Year: 2004
  7. AMYLASE BINDING STREPTOCOCCI, DENTAL PLAQUE AND CARIES
    Frank Scannapieco; Fiscal Year: 2001
  8. AMYLASE BINDING STREPTOCOCCI, DENTAL PLAQUE AND CARIES
    Frank Scannapieco; Fiscal Year: 1999
  9. Oral Health and Ventilator Associated Pneumonia
    Frank Scannapieco; Fiscal Year: 2006
  10. Amylase Binding Streptococci Dental Plaque and Caries
    Frank Scannapieco; Fiscal Year: 2005

Detail Information

Publications38

  1. ncbi request reprint Periodontitis and chronic kidney disease
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, Buffalo, NY, USA
    J Periodontol 79:1617-9. 2008
  2. ncbi request reprint Individuals With Chronic Obstructive Pulmonary Disease (COPD) May Be More Likely to Have More Severe Periodontal Disease Than Individuals Without COPD
    Frank A Scannapieco
    Professor and Chair, Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Foster Hall, Buffalo, NY 14214, USA, Tel 1 716 829 2854 Electronic address
    J Evid Based Dent Pract 14:79-81. 2014
    ..Association between periodontal disease and chronic obstructive pulmonary disease: A reality or just a dogma? Peter KP, Mute BR, Doiphode SS, Bardapurkar SJ, Borkar MS, Raj DV. J Periodontol 2013;84(12):1717-23...
  3. doi request reprint Modest reduction in risk for ventilator-associated pneumonia in critically ill patients receiving mechanical ventilation following topical oral chlorhexidine
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Foster Hall, Buffalo, New York 14214, USA
    J Evid Based Dent Pract 12:15-7. 2012
    ..Patients receiving mechanical ventilation were enrolled within 24 hours of intubation and were followed for up to 14 days. Dates of recruitment were not disclosed...
  4. ncbi request reprint Modest reduction in risk for ventilator-associated pneumonia in critically ill patients receiving mechanical ventilation following topical oral chlorhexidine
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, New York 14214, USA
    J Evid Based Dent Pract 12:103-6. 2012
  5. pmc Response of fatty acid synthesis genes to the binding of human salivary amylase by Streptococcus gordonii
    Anna E Nikitkova
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA
    Appl Environ Microbiol 78:1865-75. 2012
    ..gordonii, resulting in a phenotypic adjustment that is potentially advantageous for bacterial survival in the oral environment...
  6. pmc Interaction of salivary alpha-amylase and amylase-binding-protein A (AbpA) of Streptococcus gordonii with glucosyltransferase of S. gordonii and Streptococcus mutans
    Biswendu Chaudhuri
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, New York, USA
    BMC Microbiol 7:60. 2007
    ..We examined the interaction of amylase and recombinant AbpA (rAbpA), together with Gtfs of S. gordonii and S. mutans...
  7. ncbi request reprint Pneumonia in nonambulatory patients. The role of oral bacteria and oral hygiene
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, 109 Foster Hall, Buffalo, N Y 14214
    J Am Dent Assoc 137:21S-25S. 2006
    ..In addition, patients may aspirate inflammatory products from inflamed periodontal tissues into the lower airway, contributing to lung insult...
  8. pmc Salivary biomarkers associated with alveolar bone loss
    F A Scannapieco
    Departments of Oral Biology, School of Dental Medicine, State University at Buffalo, Buffalo, NY 14214, USA
    Ann N Y Acad Sci 1098:496-7. 2007
    ..This study provides preliminary evidence that several salivary biomarkers measured at baseline may serve to predict future alveolar bone loss...
  9. ncbi request reprint Systemic effects of periodontal diseases
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, 109 Foster Hall, Buffalo, NY 14214, USA
    Dent Clin North Am 49:533-50, vi. 2005
    ....
  10. doi request reprint "Does periodontal therapy reduce the risk for systemic diseases?"
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Foster Hall, Buffalo, NY 14214, USA
    Dent Clin North Am 54:163-81. 2010
    ..While some progress has been made, further research is required to understand the value of periodontal interventions in the prevention of systemic diseases...
  11. ncbi request reprint Periodontal disease as a risk factor for adverse pregnancy outcomes. A systematic review
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA
    Ann Periodontol 8:70-8. 2003
    ..Recent studies have implicated a variety of infections, including periodontal diseases, as risk factors for adverse pregnancy outcomes such as prematurity and low birth weight...
  12. ncbi request reprint Associations between periodontal disease and risk for nosocomial bacterial pneumonia and chronic obstructive pulmonary disease. A systematic review
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA
    Ann Periodontol 8:54-69. 2003
    ..Several recent studies provide evidence that the oral cavity may influence the initiation and/or the progression of lung diseases such as pneumonia and chronic obstructive pulmonary disease (COPD)...
  13. ncbi request reprint Associations between periodontal disease and risk for atherosclerosis, cardiovascular disease, and stroke. A systematic review
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, Buffalo, New York, USA
    Ann Periodontol 8:38-53. 2003
    ..Recent studies implicate exposure to systemic conditions involving chronic inflammation, including chronic periodontitis, in the etiology of atherosclerosis...
  14. pmc A randomized trial of chlorhexidine gluconate on oral bacterial pathogens in mechanically ventilated patients
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, 3435 Main St, Buffalo, NY 14214, USA
    Crit Care 13:R117. 2009
    ..12% chlorhexidine gluconate application necessary to reduce oral colonization by pathogens in 175 intubated patients in a trauma intensive care unit...
  15. pmc Nursing home-associated pneumonia, hospital-acquired pneumonia and ventilator-associated pneumonia: the contribution of dental biofilms and periodontal inflammation
    Krishnan Raghavendran
    Department of Surgery and Anesthesiology, School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, USA
    Periodontol 2000 44:164-77. 2007
  16. pmc Amylase-binding protein B of Streptococcus gordonii is an extracellular dipeptidyl-peptidase
    Biswendu Chaudhuri
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, Buffalo, New York 14214, USA
    Infect Immun 76:4530-7. 2008
    ..In summary, AbpB demonstrates proteolytic activity and interacts with and modulates Gtf activity. These activities may help explain the crucial role AbpB appears to play in S. gordonii oral colonization...
  17. ncbi request reprint Identification and analysis of the amylase-binding protein B (AbpB) and gene (abpB) from Streptococcus gordonii
    Lina Li
    Department of Oral Biology, 109 Foster Hall, School of Dental Medicine, State University of New York at Buffalo, 14214, USA
    FEMS Microbiol Lett 212:151-7. 2002
    ..Thus, AbpA, but not AbpB, appears sufficient to be the major receptor for amylase binding to the streptococcal surface. The role of AbpB in bacterial colonization remains to be elucidated...
  18. ncbi request reprint Supragingival plaque may modify the effects of subgingival bacteria on attachment loss
    Mine Tezal
    Department of Oral Biology, State University of New York, Buffalo, NY 14214, USA
    J Periodontol 77:808-13. 2006
    ..This study evaluates the role of supragingival plaque level on the relationship between subgingival microorganisms and the risk of attachment loss...
  19. doi request reprint Chronic periodontitis and the incidence of head and neck squamous cell carcinoma
    Mine Tezal
    Department of Oral Diagnostic Sciences, The State University of New York, Buffalo, New York 14214, USA
    Cancer Epidemiol Biomarkers Prev 18:2406-12. 2009
    ..These results have implications for practical and safe strategies for prevention, diagnosis, and treatment of HNSCC...
  20. ncbi request reprint Salivary biochemistry in Buffalo: the legacy of Michael J. Levine
    Frank A Scannapieco
    Department of Oral Biology, 109 Foster Hall, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14214, USA
    J Dent Res 82:76-81. 2003
  21. ncbi request reprint Environmental influences on Actinobacillus actinomycetemcomitans biofilm formation
    Elaine M Haase
    Department of Oral Biology, University at Buffalo, 109 Foster Hall, 3435 Main Street, Buffalo, NY 14214, USA
    Arch Oral Biol 51:299-314. 2006
    ..In conclusion, strain, growth medium and conditioning film all affect biofilm formation. The RVs produce biofilms of unique architecture that may serve to protect the bacterium from environmental perturbations...
  22. ncbi request reprint Transcriptional analysis of the 5' terminus of the flp fimbrial gene cluster from Actinobacillus actinomycetemcomitans
    Elaine M Haase
    Department of Oral Biology, School of Dental Medicine, 109 Foster Hall, University at Buffalo, State University of New York, Buffalo, NY 14214, USA
    Microbiology 149:205-15. 2003
    ..RT-PCR analysis further suggests that although transcription does occur in both the rough and smooth variants, full-length transcripts are rapidly degraded or are significantly downregulated in the smooth variant...
  23. ncbi request reprint Exposure to the dental environment and prevalence of respiratory illness in dental student populations
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, The StateUniversity of New York, Buffalo, New York 14214, USA
    J Can Dent Assoc 70:170-4. 2004
    ..To determine if the prevalence of respiratory disease among dental students and dental residents varies with their exposure to the clinical dental environment...
  24. pmc Genetic relationships between respiratory pathogens isolated from dental plaque and bronchoalveolar lavage fluid from patients in the intensive care unit undergoing mechanical ventilation
    Seok Mo Heo
    Department of Oral Biology, University at Buffalo, The State University of New York, Buffalo, NY 14214, USA
    Clin Infect Dis 47:1562-70. 2008
    ....
  25. ncbi request reprint Periodontal inflammation: from gingivitis to systemic disease?
    Frank A Scannapieco
    Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, Buffalo, New York, USA
    Compend Contin Educ Dent 25:16-25. 2004
    ..The purpose of this article is to review the possible biological pathways by which periodontal diseases may influence these disease processes...
  26. pmc Transcriptional and translational analysis of biofilm determinants of Aggregatibacter actinomycetemcomitans in response to environmental perturbation
    Jayaleka J Amarasinghe
    Department of Oral Biology, University at Buffalo, Buffalo, New York 14214, USA
    Infect Immun 77:2896-907. 2009
    ..Thus, anaerobic conditions, nutrient stress, and iron limitation each upregulate known biofilm determinants of A. actinomycetemcomitans to contribute to biofilm formation...
  27. doi request reprint Oral bacteria modulate invasion and induction of apoptosis in HEp-2 cells by Pseudomonas aeruginosa
    Yaping Pan
    Department of Oral Biology, School of Dental Medicine, 109 Foster Hall, University at Buffalo, State University of New York, 3435 Main St, Buffalo, NY 14214 3092, USA
    Microb Pathog 46:73-9. 2009
    ..These results suggest that oral bacteria, especially periodontal pathogens, may foster P. aeruginosa invasion into respiratory epithelial cells to enhance host cell cytokine release and apoptosis...
  28. ncbi request reprint Chronic periodontitis and the risk of tongue cancer
    Mine Tezal
    Department of Periodontics, State University of New York at Buffalo, NY, USA
    Arch Otolaryngol Head Neck Surg 133:450-4. 2007
    ..To assess the association between the history of chronic periodontitis and the risk of tongue cancer...
  29. ncbi request reprint History of periodontal disease diagnosis and lung cancer incidence in the Women's Health Initiative Observational Study
    Xiaodan Mai
    Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, The State University of New York, 270 Farber Hall, Buffalo, NY, 14214, USA
    Cancer Causes Control 25:1045-53. 2014
    ..Previous findings may reflect residual confounding by smoking. The study aims to determine whether history of PD diagnosis is associated with incident lung cancer in a large cohort of postmenopausal women...
  30. ncbi request reprint The use of different measurements and definitions of periodontal disease in the study of the association between periodontal disease and risk of myocardial infarction
    Oelisoa M Andriankaja
    School of Public Health and Health Professions, University at Buffalo, NY 14214, USA
    J Periodontol 77:1067-73. 2006
    ..The present study assesses if the observed association between periodontal disease and incident myocardial infarction (MI) depends on the measurements and/or criteria used to define periodontal disease...
  31. ncbi request reprint The epidemiology, consequences and management of periodontal disease in older adults
    Tobias K Boehm
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, State University of New York, USA
    J Am Dent Assoc 138:26S-33S. 2007
    ..This review summarizes the literature on periodontal disease (PD) in older adults. The authors focused on significant sequelae of PD and therapy in this population...
  32. ncbi request reprint Molecular analysis of bacterial flora associated with chronically inflamed maxillary sinuses
    Susanna Paju
    Department of Oral Biology, School of Dental Medicine and Department of Otolaryngology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14214, USA
    J Med Microbiol 52:591-7. 2003
    ..These results suggest that both aerobic and anaerobic bacteria can be detected in nearly half of chronic maxillary sinusitis cases...
  33. pmc Candidate salivary biomarkers associated with alveolar bone loss: cross-sectional and in vitro studies
    Patricia Yen Bee Ng
    Department of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14214, USA
    FEMS Immunol Med Microbiol 49:252-60. 2007
    ..These results suggest that detection of biomarkers by conventional immunoassays may underestimate the actual quantity of molecules in saliva...
  34. ncbi request reprint Special-needs patients
    Frank A Scannapieco
    J Am Dent Assoc 136:1512. 2005
  35. ncbi request reprint The relationship between periodontal diseases and respiratory diseases
    Frank A Scannapieco
    Dent Today 22:79-83. 2003
  36. ncbi request reprint Inhibition of proinflammatory activities of major periodontal pathogens by aqueous extracts from elder flower (Sambucus nigra)
    Evlambia Harokopakis
    Department of Pedodontics, School of Dentistry, Center of Excellence in Oral and Craniofacial Biology, Louisiana State University Health Sciences Center, New Orleans, LA, USA
    J Periodontol 77:271-9. 2006
    ....
  37. ncbi request reprint Nosocomial pneumonia and oral health
    Kenneth Shay
    Veterans Integrated Service Network 11, Dept of Veterans Affairs, Ann Arbor, MI, USA
    Spec Care Dentist 25:179-87. 2005
    ..The goal of this review is to alert the reader to the role that oral disease and oral health play in fostering and preventing, respectively, widespread and potentially fatal pulmonary disease among high-risk individuals...
  38. ncbi request reprint Perceptions of dental schools from within and outside the university
    Douglas N Dederich
    Department of Periodontics, LSU School of Dentistry, 1100 Florida Avenue, Box 138, New Orleans, LA 70119 2799, USA
    J Dent Educ 68:1163-71. 2004
    ..We suggest that these hypotheses form the basis of subsequent, more targeted, follow-up investigations with the intent of formulating specific recommendations for action...

Research Grants13

  1. Amylase Binding Streptococci Dental Plaque and Caries
    Frank Scannapieco; Fiscal Year: 2007
    ..mutans made to express AbpA show altered colonization and/or cariogenic abilities. Integration of in vitro with in vivo studies is crucial for mechanistic understanding of Dental plaque formation. ..
  2. Amylase Binding Streptococci Dental Plaque and Caries
    Frank Scannapieco; Fiscal Year: 2006
    ..mutans made to express AbpA show altered colonization and/or cariogenic abilities. Integration of in vitro with in vivo studies is crucial for mechanistic understanding of Dental plaque formation. ..
  3. Oral Health and Ventilator Associated Pneumonia
    Frank Scannapieco; Fiscal Year: 2005
    ..abstract_text> ..
  4. AMYLASE BINDING STREPTOCOCCI, DENTAL PLAQUE AND CARIES
    Frank Scannapieco; Fiscal Year: 2000
    ..Such studies are crucial to better understand oral biofilm formation, which causes dental caries and periodontitis. ..
  5. Amylase Binding Streptococci Dental Plaque and Caries
    Frank Scannapieco; Fiscal Year: 2004
    ..mutans made to express AbpA show altered colonization and/or cariogenic abilities. Integration of in vitro with in vivo studies is crucial for mechanistic understanding of Dental plaque formation. ..
  6. Oral Health and Ventilator Associated Pneumonia
    Frank Scannapieco; Fiscal Year: 2004
    ..abstract_text> ..
  7. AMYLASE BINDING STREPTOCOCCI, DENTAL PLAQUE AND CARIES
    Frank Scannapieco; Fiscal Year: 2001
    ..Such studies are crucial to better understand oral biofilm formation, which causes dental caries and periodontitis. ..
  8. AMYLASE BINDING STREPTOCOCCI, DENTAL PLAQUE AND CARIES
    Frank Scannapieco; Fiscal Year: 1999
    ..Such studies are crucial to better understand oral biofilm formation, which causes dental caries and periodontitis. ..
  9. Oral Health and Ventilator Associated Pneumonia
    Frank Scannapieco; Fiscal Year: 2006
    ..abstract_text> ..
  10. Amylase Binding Streptococci Dental Plaque and Caries
    Frank Scannapieco; Fiscal Year: 2005
    ..mutans made to express AbpA show altered colonization and/or cariogenic abilities. Integration of in vitro with in vivo studies is crucial for mechanistic understanding of Dental plaque formation. ..