T M Scalea

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi request reprint Increased intra-abdominal, intrathoracic, and intracranial pressure after severe brain injury: multiple compartment syndrome
    Thomas M Scalea
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, MD 21201, USA
    J Trauma 62:647-56; discussion 656. 2007
  2. doi request reprint Western Trauma Association critical decisions in trauma: management of the mangled extremity
    Thomas M Scalea
    R Adams Cowley Shock Trauma Center, Baltimore, MD 21201, USA
    J Trauma Acute Care Surg 72:86-93. 2012
  3. pmc Vascular injuries after blunt chest trauma: diagnosis and management
    James V O'Connor
    R Adams Cowley Shock Trauma Center, Baltimore, USA
    Scand J Trauma Resusc Emerg Med 17:42. 2009
  4. doi request reprint Early aggressive use of fresh frozen plasma does not improve outcome in critically injured trauma patients
    Thomas M Scalea
    R Adams Cowley Shock Trauma Center, Division of Clinical and Outcomes Research, Department of Surgery, Anesthesiology, and Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Ann Surg 248:578-84. 2008
  5. ncbi request reprint Optimal timing of fracture fixation: have we learned anything in the past 20 years?
    Thomas M Scalea
    Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 65:253-60. 2008
  6. ncbi request reprint Interventional techniques in vascular trauma
    T M Scalea
    R Adams Cowley Shock Trauma Center, Program in Trauma, University of Maryland School of Medicine, Baltimore 20201, USA
    Surg Clin North Am 81:1281-97, xii. 2001
  7. ncbi request reprint Pelvic fracture in geriatric patients: a distinct clinical entity
    Sharon M Henry
    Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Trauma 53:15-20. 2002
  8. ncbi request reprint Tight glycemic control in critically injured trauma patients
    Thomas M Scalea
    R Adams Cowley Shock Trauma Center, Division of Clinical and Outcomes Research, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Ann Surg 246:605-10; discussion 610-2. 2007
  9. pmc Hemostatic resuscitation for acute traumatic coagulopathy
    Thomas M Scalea
    Surgical Critical Care and Emergency Medicine, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, USA
    Scand J Trauma Resusc Emerg Med 19:2. 2011
  10. ncbi request reprint Admission preoperative glucose is predictive of morbidity and mortality in trauma patients who require immediate operative intervention
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center and University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Am Surg 71:171-4. 2005

Detail Information

Publications96

  1. ncbi request reprint Increased intra-abdominal, intrathoracic, and intracranial pressure after severe brain injury: multiple compartment syndrome
    Thomas M Scalea
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, MD 21201, USA
    J Trauma 62:647-56; discussion 656. 2007
    ..Both decompressive craniectomy (DC) and decompressive laparotomy (DL) decrease ICP. DL can also decrease IAP and ICP. We evaluated the serial application of DC and DL to treat MCS...
  2. doi request reprint Western Trauma Association critical decisions in trauma: management of the mangled extremity
    Thomas M Scalea
    R Adams Cowley Shock Trauma Center, Baltimore, MD 21201, USA
    J Trauma Acute Care Surg 72:86-93. 2012
    ..We have sought to develop an evidence-based algorithm to help guide practitioners when faced with these relatively infrequent but very challenging clinical dilemmas...
  3. pmc Vascular injuries after blunt chest trauma: diagnosis and management
    James V O'Connor
    R Adams Cowley Shock Trauma Center, Baltimore, USA
    Scand J Trauma Resusc Emerg Med 17:42. 2009
    ..The goal of this review is to update the reader on current concepts of diagnosis and management of blunt thoracic vascular trauma...
  4. doi request reprint Early aggressive use of fresh frozen plasma does not improve outcome in critically injured trauma patients
    Thomas M Scalea
    R Adams Cowley Shock Trauma Center, Division of Clinical and Outcomes Research, Department of Surgery, Anesthesiology, and Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Ann Surg 248:578-84. 2008
    ..Recent data from Iraq supporting early aggressive use of fresh frozen plasma (FFP) in a 1:1 ratio to packed red blood cells (PRBCs) has led many civilian trauma centers to adopt this resource intensive strategy...
  5. ncbi request reprint Optimal timing of fracture fixation: have we learned anything in the past 20 years?
    Thomas M Scalea
    Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 65:253-60. 2008
  6. ncbi request reprint Interventional techniques in vascular trauma
    T M Scalea
    R Adams Cowley Shock Trauma Center, Program in Trauma, University of Maryland School of Medicine, Baltimore 20201, USA
    Surg Clin North Am 81:1281-97, xii. 2001
    ..This article addresses in detail the newer role for interventional angiography, including diagnosis and newer angioembolization techniques used to control bleeding and to deal with complications of vascular injuries...
  7. ncbi request reprint Pelvic fracture in geriatric patients: a distinct clinical entity
    Sharon M Henry
    Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Trauma 53:15-20. 2002
    ..The purpose of this study was to describe differences in demographics, injury pattern, transfusion needs, and outcome of pelvic fractures in older versus younger patients...
  8. ncbi request reprint Tight glycemic control in critically injured trauma patients
    Thomas M Scalea
    R Adams Cowley Shock Trauma Center, Division of Clinical and Outcomes Research, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Ann Surg 246:605-10; discussion 610-2. 2007
    ..Evaluate the impact of a tight glucose control (TGC) protocol during the first week of admission in critically injured trauma patients...
  9. pmc Hemostatic resuscitation for acute traumatic coagulopathy
    Thomas M Scalea
    Surgical Critical Care and Emergency Medicine, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, USA
    Scand J Trauma Resusc Emerg Med 19:2. 2011
    ..Dilutional anemia was relatively common. Patients with large volume blood loss often died from what was termed, "the bloody vicious cycle," of hypothermia, acidosis and coagulopathy...
  10. ncbi request reprint Admission preoperative glucose is predictive of morbidity and mortality in trauma patients who require immediate operative intervention
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center and University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Am Surg 71:171-4. 2005
    ..Elevated serum glucose on admission is an accurate predictor of postoperative infection, HLOS, ILOS, and mortality. A randomized prospective trial evaluating the impact of preoperative glucose control is warranted...
  11. ncbi request reprint Impact of nosocomial infections in trauma: does age make a difference?
    G V Bochicchio
    R Adams Cowley Shock Trauma Center and the University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 50:612-7; discussion 617-9. 2001
    ..We evaluated the incidence and impact that nosocomial infection (NI) and age have on morbidity and mortality. Several risk factors were identified and analyzed for correlation with infection...
  12. ncbi request reprint Lactate and base deficit in trauma: does alcohol or drug use impair their predictive accuracy?
    James R Dunne
    University of Maryland School of Medicine, R Adams Cowley Shock Trauma Center, Baltimore, Maryland 21201, USA
    J Trauma 58:959-66. 2005
    ..We, therefore, sought to examine the effect of alcohol and drug use on the predictive accuracy of admission blood lactate and BD in trauma...
  13. doi request reprint Trauma mortality in mature trauma systems: are we doing better? An analysis of trauma mortality patterns, 1997-2008
    Richard P Dutton
    Program in Trauma, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Trauma 69:620-6. 2010
    ..We examined injury severity, mortality, and preventability in a mature trauma system during a 12-year period to assess the overall benefits of these and other improvements...
  14. ncbi request reprint Recombinant factor VIIa for control of hemorrhage: early experience in critically ill trauma patients
    Richard P Dutton
    Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD, USA
    J Clin Anesth 15:184-8. 2003
    ..To examine our institutional experience with recombinant Factor VIIa (rFVIIa) as a treatment for exsanguinating hemorrhage in critically ill trauma patients...
  15. ncbi request reprint Decompressive laparotomy to treat intractable intracranial hypertension after traumatic brain injury
    D Andrea K Joseph
    Program in Trauma, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 57:687-93; discussion 693-5. 2004
    ..Recently, we noticed that abdominal fascial release could be useful in treating intracranial hypertension (ICH) after traumatic brain injury (TBI). We added this as an option in our treatment of TBI...
  16. ncbi request reprint Factor VIIa for correction of traumatic coagulopathy
    Richard P Dutton
    Program in Trauma, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 57:709-18; discussion 718-9. 2004
    ..We present our experience with 81 coagulopathic trauma patients treated using FVIIa in years 2001-2003, compared with "control" patients matched from the trauma registry from the same time period...
  17. ncbi request reprint Nonsurgical management of blunt splenic injury: use of CT criteria to select patients for splenic arteriography and potential endovascular therapy
    K Shanmuganathan
    Department of Radiology, University of Maryland Medical Center, 22 S Greene St, Baltimore, MD 21201, USA
    Radiology 217:75-82. 2000
    ..To determine if contrast material-enhanced spiral computed tomography (CT) can be used to select patients with blunt splenic injuries to undergo arteriographic embolization...
  18. ncbi request reprint Admission hyperglycemia is predictive of outcome in critically ill trauma patients
    Jin Sung
    Department of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Trauma 59:80-3. 2005
    ..Our objectives were to determine whether admission hyperglycemia was predictive of outcome in critically ill trauma patients...
  19. doi request reprint Posttraumatic cerebral infarction: incidence, outcome, and risk factors
    Isaac Tawil
    Division of Trauma Critical Care, Department of Surgery, University of New Mexico, Albuquerque, New Mexico, USA
    J Trauma 64:849-53. 2008
    ..We suspected that recent advances in imaging modalities and treatment might affect incidence and outcome. We sought to define the incidence and mortality impact of PTCI. We also identified risk factors associated with PTCI...
  20. ncbi request reprint Blood transfusion rates in the care of acute trauma
    John J Como
    R Adams Cowley Shock Trauma Center and the Department of Pathology, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    Transfusion 44:809-13. 2004
    ..Understanding patterns of RBC use is important. Routine resource allocation, planning for mass casualty situations, designing research, and optimizing triage all can be usefully informed...
  21. ncbi request reprint Ligamentous injuries of the cervical spine in unreliable blunt trauma patients: incidence, evaluation, and outcome
    W C Chiu
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Trauma 50:457-63; discussion 464. 2001
    ....
  22. ncbi request reprint Blood transfusion, independent of shock severity, is associated with worse outcome in trauma
    Debra L Malone
    Department of Surgery, University of Maryland School of Medicine and R Adams Cowley Shock Trauma Center, Baltimore, 21201, USA
    J Trauma 54:898-905; discussion 905-7. 2003
    ....
  23. ncbi request reprint Hypotensive resuscitation during active hemorrhage: impact on in-hospital mortality
    Richard P Dutton
    R Adams Cowley Shock Trauma Center and the Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 52:1141-6. 2002
    ..We hypothesized that fluid resuscitation titrated to a lower than normal SBP during the period of active hemorrhage would improve survival in trauma patients presenting to the hospital in hemorrhagic shock...
  24. ncbi request reprint Systemic inflammatory response syndrome score at admission independently predicts mortality and length of stay in trauma patients
    L M Napolitano
    R Adams Cowley Shock Trauma Center, Department of Surgery, University of Maryland School of Medicine, Baltimore, USA
    J Trauma 49:647-52; discussion 652-3. 2000
    ..We sought to determine whether the severity of SIRS at admission is an accurate predictor of mortality and length of stay (LOS) in trauma patients...
  25. ncbi request reprint Role of ultrasonography in penetrating abdominal trauma: a prospective clinical study
    K F Udobi
    Department of Surgery, Kansas University School of Medicine, Kansas City, Kansas, USA
    J Trauma 50:475-9. 2001
    ..A positive FAST is a strong predictor of injury, and patients should proceed directly to laparotomy. If negative, additional diagnostic studies should be performed to rule out occult injury...
  26. ncbi request reprint Determining the need for laparotomy in penetrating torso trauma: a prospective study using triple-contrast enhanced abdominopelvic computed tomography
    W C Chiu
    Section of Trauma Surgery, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 1595, USA
    J Trauma 51:860-8; discussion 868-9. 2001
    ..We prospectively investigated the current utility of triple-contrast CT as a diagnostic tool to facilitate initial therapeutic management decisions in penetrating torso trauma...
  27. ncbi request reprint Reevaluating the management and outcomes of severe blunt liver injury
    Therese M Duane
    Department of Surgery, Division of Trauma Critical Care, West Hospital, Medical College of Virginia Virginia Commonwealth University, Richmond, Virginia, USA
    J Trauma 57:494-500. 2004
    ..We also sought to determine the impact of interventional angiography (Ang) in the treatment and outcomes of these patients...
  28. ncbi request reprint Outcome following decompressive craniectomy for malignant swelling due to severe head injury
    Bizhan Aarabi
    Department of Neurosurgery and R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Neurosurg 104:469-79. 2006
    ..The aim of this study was to assess outcome following decompressive craniectomy for malignant brain swelling due to closed traumatic brain injury (TBI)...
  29. ncbi request reprint Systemic inflammatory response syndrome and nosocomial infection in trauma
    Leslie Hoover
    R Adams Cowley Shock Trauma Center, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 61:310-6; discussion 316-7. 2006
    ....
  30. ncbi request reprint Admission angiography for blunt splenic injury: advantages and pitfalls
    J Haan
    Department of Surgery, University of Maryland School of Medicine, Baltimore, USA
    J Trauma 51:1161-5. 2001
    ..To analyze the use of admission angiography as a nonoperative adjunct for management of blunt splenic injury...
  31. ncbi request reprint Systemic inflammatory response syndrome score at admission independently predicts infection in blunt trauma patients
    G V Bochicchio
    Department of Surgery, R Adams Cowley Shock Trauma Center, 22 South Greene Street, Baltimore, MD 21201, USA
    J Trauma 50:817-20. 2001
    ..Our goal was to determine whether the severity of SIRS score at admission is an accurate predictor of infection in trauma patients...
  32. ncbi request reprint Long term impact of damage control surgery: a preliminary prospective study
    Erica Sutton
    R Adams Cowley Shock Trauma Center, Division of Clinical and Outcomes Research, University of Maryland School of Medicine, MD, USA
    J Trauma 61:831-4; discussion 835-6. 2006
    ..To evaluate the impact of damage control laparotomy on long term morbidity and survival...
  33. doi request reprint Controversy in trauma resuscitation: do ratios of plasma to red blood cells matter?
    Lynn G Stansbury
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, USA
    Transfus Med Rev 23:255-65. 2009
    ..In this review, the authors examine the findings of these initial studies, highlighting the epidemiologic and analytic methodologies used, and the likely influence of these methodologies on the reported outcomes...
  34. ncbi request reprint Damage control for torso trauma
    Thomas M Scalea
    Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Hosp Med 66:84-7. 2005
  35. ncbi request reprint Gender differences in adverse outcomes after blunt trauma
    L M Napolitano
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Room N4E27, 22 South Greene Street, Baltimore, MD 21201, USA
    J Trauma 50:274-80. 2001
    ..Adams Cowley Shock Trauma Center, the adult trauma resource center for the state of Maryland...
  36. doi request reprint Impediments to obtaining informed consent for clinical research in trauma patients
    Richard P Dutton
    Departments of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Trauma 64:1106-12. 2008
    ..Informed consent is required for, but a substantial barrier to, clinic research in trauma care. Exceptions have been established but remain controversial, and little objective data are available to illuminate this debate...
  37. ncbi request reprint Thromboembolic complications associated with factor VIIa administration
    G O Rhys Thomas
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, MD 21201, USA
    J Trauma 62:564-9. 2007
    ..FVIIa is associated with thromboembolic complications, but the incidence is not known, nor is which patients are at risk. We examined our experience with FVIIa to better understand this issue...
  38. ncbi request reprint Safety of uncrossmatched type-O red cells for resuscitation from hemorrhagic shock
    Richard P Dutton
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 59:1445-9. 2005
    ..We examined a 1-year experience with UORBC transfusion to determine the incidence of allergic reaction and alloimmunization...
  39. ncbi request reprint The importance of fracture pattern in guiding therapeutic decision-making in patients with hemorrhagic shock and pelvic ring disruptions
    Brian J Eastridge
    Department of Surgery, University of Texas Southwestern Medical Center, Dallas 75390, USA
    J Trauma 53:446-50; discussion 450-1. 2002
    ....
  40. ncbi request reprint Decompressive laparotomy: a novel approach in the management of severe intracranial hypertension
    Maurizio A Miglietta
    Trauma and Surgical Critical Care, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, 21201 1595, USA
    J Trauma 55:551-4; discussion 554-5. 2003
  41. ncbi request reprint Daily multidisciplinary rounds shorten length of stay for trauma patients
    Richard P Dutton
    Division of Trauma Anesthesiology, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    J Trauma 55:913-9. 2003
    ..We hypothesized that daily multidisciplinary "discharge rounds" would improve patient flow and increase readiness...
  42. doi request reprint Automated measurement of "pressure times time dose" of intracranial hypertension best predicts outcome after severe traumatic brain injury
    Sibel Kahraman
    Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 69:110-8. 2010
    ..We assessed the accuracy and utility of high-resolution automated intracranial pressure (ICP) and cerebral perfusion pressure (CPP) recording and their analysis in patients with severe TBI...
  43. ncbi request reprint Protocol-driven nonoperative management in patients with blunt splenic trauma and minimal associated injury decreases length of stay
    James Haan
    Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21201 1595, USA
    J Trauma 55:317-21; discussion 321-2. 2003
    ..The purpose of this study was to analyze the impact of more selective use of admission angiography combined with protocolized nonoperative management for blunt splenic injury...
  44. ncbi request reprint Admission serum albumin is predicitve of outcome in critically ill trauma patients
    Jin Sung
    R Adams Cowley Shock Trauma Center, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Am Surg 70:1099-102. 2004
    ..The combination of increased age and low albumin level was most predictive of infection and mortality. Early nutrition should be considered in these high-risk patients...
  45. ncbi request reprint Experience with spiral computed tomography as the sole diagnostic method for traumatic aortic rupture
    S W Downing
    Department of Surgery, University of Maryland School of Medicine, R Adams Crowley Shock Trauma Center, Baltimore, USA
    Ann Thorac Surg 72:495-501; discussion 501-2. 2001
    ..Traditionally, aortography is performed when injury is suspected to confirm the diagnosis. We hypothesized that it is safe and expeditious to forgo aortography when the spiral CT demonstrates aortic injury...
  46. ncbi request reprint Total cytokine immunoassay: a more accurate method of cytokine measurement?
    D Malone
    University of Maryland School of Medicine and the R Adams Cowley Shock Trauma Center, Baltimore, Maryland, USA
    J Trauma 50:821-5. 2001
    ....
  47. pmc Percutaneous endoscopic gastrostomy in the supermorbidly obese patient
    Grant V Bochicchio
    Division of Clinical and Outcomes Research, The R Adams Cowley Shock Trauma Center and University of Maryland School of Medicine, Department of Surgery, Baltimore, Maryland, USA
    JSLS 10:409-13. 2006
    ..We prospectively evaluated the success rate of percutaneous endoscopic gastrostomy (PEG) placement in a group of morbidly obese patients outside the current classification systems used to stratify obesity...
  48. ncbi request reprint Discharge rounds in the 80-hour workweek: importance of the trauma nurse practitioner
    James M Haan
    Department of Trauma Surgical Critical Care, Baltimore, Maryland 21201, USA
    J Trauma 63:339-43. 2007
    ..Certified nurse practitioners (CRNPs) were added to the trauma teams to assist in patient care and represent the team on discharge rounds, replacing the fellows. We hypothesized that this would offset any potential negative effects...
  49. ncbi request reprint Coagulation and complement protein differences between septic and uninfected systemic inflammatory response syndrome patients
    Matthew E Lissauer
    R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore 21201, USA
    J Trauma 62:1082-92; discussion 1092-4. 2007
    ..This experiment was designed to evaluate differences in plasma protein profiles between clinically identical patients: septic versus uninfected SIRS patients, prior to clinical diagnosis of infection...
  50. doi request reprint Association of CSF biomarkers and secondary insults following severe traumatic brain injury
    Deborah M Stein
    Division of Critical Care Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Neurocrit Care 14:200-7. 2011
    ..This pilot study was undertaken to investigate the relationship of S100β and NSE to clinical markers of severity and poor outcome: intracranial hypertension (ICH), and cerebral hypoperfusion (CH)...
  51. ncbi request reprint Blast injury in a civilian trauma setting is associated with a delay in diagnosis of traumatic brain injury
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center, Division of Clinical and Outcomes Research, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Am Surg 74:267-70. 2008
    ..The missed injury rate for TBI in patients with a Glasgow Coma Scale score of 15 was 36 per cent. More studies are needed in the area of blast injury to better understand this disease process...
  52. doi request reprint Crash and occupant predictors of pulmonary contusion
    James V O'Connor
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Trauma 66:1091-5. 2009
    ..The crash and occupant characteristics of PC in motor vehicle collisions are currently unknown. Additionally, the clinical significance and the impact on mortality have not been determined...
  53. doi request reprint Acute glucose elevation is highly predictive of infection and outcome in critically injured trauma patients
    Grant V Bochicchio
    Division of Clinical and Outcomes Research, Department of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Ann Surg 252:597-602. 2010
    ..To evaluate whether acute glucose elevation (AGE) is predictive of infection and outcome in critically injured trauma patients during the first 14 days of ICU admission...
  54. doi request reprint Treatment of major hepatic necrosis: lobectomy versus serial debridement
    Danielle N Dabbs
    R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    J Trauma 69:562-7. 2010
    ..Major hepatic necrosis (MHN) is a common complication after angioembolization (AE) for severe liver injuries. We compared the outcomes of two treatment modalities...
  55. doi request reprint Outcome analysis of blood product transfusion in trauma patients: a prospective, risk-adjusted study
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center Programs in Trauma, 22 South Greene Street, Baltimore, MD 21201, USA
    World J Surg 32:2185-9. 2008
    ..The objective of this study was to examine risk-adjusted outcome in trauma with stratification by blood product type...
  56. doi request reprint Resuscitation before stabilization of femoral fractures limits acute respiratory distress syndrome in patients with multiple traumatic injuries despite low use of damage control orthopedics
    Robert V O'Toole
    Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 67:1013-21. 2009
    ..Damage control orthopedics (DCO) with primary external fixation usually is reserved for those rare patients who do not respond to resuscitation. Our hypothesis was that this approach yields a low rate of ARDS...
  57. doi request reprint Pulmonary embolism after injury: more common than we think?
    Jay Menaker
    R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    J Trauma 67:1244-9. 2009
    ..We hypothesized that an increased awareness of early PE would result in an increased incidence, an earlier diagnosis, and a decreased mortality of PE after injury...
  58. ncbi request reprint Glycemic control in the ICU
    Grant V Bochicchio
    University of Maryland School of Medicine, Room T1R59, R Adams Cowley Shock Trauma Center, 22 South Greene Street, Baltimore, MD 21201, USA
    Adv Surg 42:261-75. 2008
    ..Many of these devices, such as the Optiscanner, which measures plasma glucose continuously, are on the horizon and should be approved by the FDA in 2008...
  59. doi request reprint Geriatric care in the surgical intensive care unit
    Jay Menaker
    Department of Surgery, Division of Surgical Critical Care, Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD, USA
    Crit Care Med 38:S452-9. 2010
    ..The management of the elderly, surgical, critical care patient is extremely challenging. Understanding age-related physiologic changes will help guide treatment to maximize outcome and prevent complications...
  60. doi request reprint Differential expression of toll-like receptor genes: sepsis compared with sterile inflammation 1 day before sepsis diagnosis
    Matthew E Lissauer
    Department of Surgical Critical Care, University of Maryland Medical Center, Room S4D07, 22 S Greene St, Baltimore, MD 21201, USA
    Shock 31:238-44. 2009
    ..These expression differences occur before phenotypic-based diagnosis of clinical sepsis...
  61. ncbi request reprint Retrograde esophageal intubation
    Thomas M Scalea
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Am Surg 73:267-70. 2007
    ..Retrograde esophageal intubation is simple, can be used long-term, and allows control of esophageal secretions without cervical esophagostomy. Esophageal length is preserved and can be used as part of a damage control operation...
  62. ncbi request reprint Prediction of outcomes in trauma: anatomic or physiologic parameters?
    James L Guzzo
    Department of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Am Coll Surg 201:891-7. 2005
    ..The objective of this study was to compare the predictive abilities of these statistical models in trauma outcomes...
  63. ncbi request reprint Exclusion of unstable cervical spine injury in obtunded patients with blunt trauma: is MR imaging needed when multi-detector row CT findings are normal?
    Gerard J Hogan
    Department of Diagnostic Radiology, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201, USA
    Radiology 237:106-13. 2005
    ....
  64. ncbi request reprint Percutaneous endoscopic gastrostomy in ICU patients with previous laparotomy
    James L Guzzo
    Division of Clinical and Outcomes Research, The R Adams Cowley Shock Trauma Center, and University of Maryland School of Medicine Department of Surgery, Baltimore, Maryland 21201, USA
    Am Surg 71:420-3. 2005
    ..PEG should be considered in all patients with previous laparotomy in need for long-term enteral access...
  65. ncbi request reprint Summary report on current clinical trauma care fellowship training programs
    William C Chiu
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 1595, USA
    J Trauma 58:605-13. 2005
    ..These perceived problems still exist and may threaten the future of trauma surgery as a career. The objective of this study was to examine these issues in a profile of the current active clinical trauma care fellowship training programs...
  66. ncbi request reprint Splenic embolization revisited: a multicenter review
    James M Haan
    Department of Surgical Critical Care, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, 22 South Green Street, Baltimore, MD 21201 1595, USA
    J Trauma 56:542-7. 2004
    ..Splenic embolization can increase nonoperative salvage. However, complications are not clearly defined. A retrospective multicenter review was performed to delineate the risks and benefits of splenic embolization...
  67. ncbi request reprint Reclassification of urinary tract infections in critically ill trauma patients: a time-dependent analysis
    Grant V Bochicchio
    Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Surg Infect (Larchmt) 4:379-85. 2003
    ..We evaluated the incidence and microbiology of UTIs stratified by days post-admission and risk factors...
  68. ncbi request reprint Impact of culture and policy on organ donation: a comparison between two urban trauma centers in developed nations
    Maureen McCunn
    Department of Critical Care Medicine, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, 21202, USA
    J Trauma 54:995-9. 2003
    ..The similarities and differences in organ donation policies, consent rates, and number of organs transplanted from patients declared "brain dead" after traumatic injury in different countries has not been previously reported...
  69. ncbi request reprint Endotracheal intubation in the field does not improve outcome in trauma patients who present without an acutely lethal traumatic brain injury
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center and University of Maryland Medical School, Baltimore, 21201, USA
    J Trauma 54:307-11. 2003
    ....
  70. ncbi request reprint Detrimental effects of rapid fluid resuscitation on hepatocellular function and survival after hemorrhagic shock
    Kaushal J Shah
    Department of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore 21201, USA
    Shock 18:242-7. 2002
    ..05). Thus, overly aggressive fluid tx accelerates hepatocellular injury, is no better than lesser rates of resuscitation at correcting plasma lactate and preserving renal function, and provides no overall survival benefit...
  71. doi request reprint Endograft repair of traumatic aortic injury-a technique in evolution: a single institution's experience
    David G Neschis
    Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA
    Ann Surg 250:377-82. 2009
    ..Endograft repair of these injuries has reduced the rates of death and paraplegia seen with open surgical treatment in the past. However, endograft repair has been associated with a higher incidence of device related failure...
  72. ncbi request reprint Impact of obesity in the critically ill trauma patient: a prospective study
    Grant V Bochicchio
    Department of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    J Am Coll Surg 203:533-8. 2006
    ..Obesity has risen at an epidemic rate over the past 20 years in the US. To our knowledge, there is an absence of data evaluating the impact of obesity in the critically ill trauma patient...
  73. ncbi request reprint Nonoperative management of spleen and liver injuries
    Deborah M Stein
    Division of Critical Care Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Intensive Care Med 21:296-304. 2006
    ..This review will discuss current concepts in nonoperative management of liver and spleen, including diagnosis, patient selection, nonoperative management strategies, benefits, risks, and complications...
  74. ncbi request reprint Hypotensive hemorrhage increases calcium uptake capacity and Bcl-XL content of liver mitochondria
    Drew E Carlson
    Program in Trauma and Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Shock 27:192-8. 2007
    ..Thus, mitochondrial mechanisms are triggered early during reversible hypovolemia that may limit the intensity of intracellular calcium signaling and its potential to cause cellular injury and death...
  75. ncbi request reprint Tolerance and efficacy of enteral nutrition in traumatic brain-injured patients induced into barbiturate coma
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center, Division of Clinical and Outcomes Research, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    JPEN J Parenter Enteral Nutr 30:503-6. 2006
    ..Our objective was to evaluate the efficacy of enteral nutrition in a select group of trauma patients...
  76. ncbi request reprint Therapeutic aspects of fat embolism syndrome
    Nader M Habashi
    Multi Trauma Critical Care, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, USA
    Injury 37:S68-73. 2006
    ..The main therapeutic interventions once FES has been clinically diagnosed are directed towards support of pulmonary and neurological manifestations and management of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)...
  77. ncbi request reprint Surgeon-performed focused assessment with sonography for trauma as an early screening tool for pregnancy after trauma
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center and the Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 52:1125-8. 2002
    ..We sought to determine the utility and impact of the initial ultrasound examination in the diagnosis of pregnancy in female trauma patients...
  78. ncbi request reprint Epidemic increases in cocaine and opiate use by trauma center patients: documentation with a large clinical toxicology database
    C A Soderstrom
    R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, 22 S Greene St, Baltimore, MD 21201, USA
    J Trauma 51:557-64. 2001
    ..We assessed substance use trends in a large cohort of patients admitted to a regional Level I adult trauma center between July 1984 and June 2000...
  79. ncbi request reprint Multidisciplinary approach for patients with pelvic fractures and hemodynamic instability
    D M Stein
    R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    Scand J Surg 96:272-80. 2007
    ..The key to successful management of these patients lies in the careful coordination of different specialists and the expertise that each brings to the clinical care of the patient...
  80. ncbi request reprint Extracorporeal support in an adult with severe carbon monoxide poisoning and shock following smoke inhalation: a case report
    M McCunn
    Department of Critical Care Medicine, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore 21201, USA
    Perfusion 15:169-73. 2000
    ..When oxygenation and ventilation cannot be achieved via maximal ventilatory management, extracorporeal support may prevent death if initiated rapidly...
  81. ncbi request reprint Triple-contrast helical CT in penetrating torso trauma: a prospective study to determine peritoneal violation and the need for laparotomy
    K Shanmuganathan
    Department of Diagnostic Radiology, University of Maryland Medical Center, 22 S. Greene St, Baltimore, MD 21201, USA
    AJR Am J Roentgenol 177:1247-56. 2001
    ..CONCLUSION: Triple-contrast helical CT can accurately predict the need for laparotomy and exclude peritoneal violation in penetrating torso trauma including tangential abdominal wounds...
  82. ncbi request reprint A time-dependent analysis of intensive care unit pneumonia in trauma patients
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center and University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 56:296-301; discussion 301-3. 2004
    ..Appropriate and timely antibiotic therapy to treat pneumonia in trauma patients is extremely important. We evaluated the incidence and microbiology of pneumonia stratified by days postadmission and risk factors...
  83. ncbi request reprint Chyloperitoneum after blunt abdominal injury
    James M Haan
    University of Maryland, R Adams Cowley Shock Trauma Center, Baltimore, Maryland 21201, USA
    Am Surg 73:811-3. 2007
    ..Open ligation or clipping of the injured ducts seems effective. Tube feeds with medium chain triglycerides may enhance efficacy of operative treatment...
  84. ncbi request reprint Diagnostic utility of sublingual PCO2 for detecting hemorrhage in penetrating trauma patients
    Bonny J Baron
    Department of Emergency Medicine, State University of New York Downstate Medical Center and Kings County Hospital Center, Brooklyn, New York 11203, USA
    J Trauma 57:69-74. 2004
    ..Studies have shown that sublingual Pco2 (SLCO2) correlates with gut perfusion. We tested SLCO2's ability to detect hemorrhage. We compared SLCO2 with arterial base deficit (BD) and lactate (LAC)...
  85. ncbi request reprint Incidence of early pulmonary embolism after injury
    Jay Menaker
    R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore, Maryland, USA
    J Trauma 63:620-4. 2007
    ..PE is generally thought to occur days after the acute injury. Hypoxia early after injury is often ascribed to other causes. We hypothesized that PE often occurs early after injury and we sought to elucidate the timing of PE after trauma...
  86. ncbi request reprint Risk factors associated with pelvic fractures sustained in motor vehicle collisions involving newer vehicles
    Deborah M Stein
    Program in Trauma, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 61:21-30; discussion 30-1. 2006
    ..We utilized the Crash Injury Research Engineering Network (CIREN) database to identify these risk factors in newer vehicles...
  87. doi request reprint Computed tomography alone for cervical spine clearance in the unreliable patient--are we there yet?
    Jay Menaker
    University of Maryland Medical Center, R Adams Cowley Shock Trauma Center, Baltimore, MD, USA
    J Trauma 64:898-903; discussion 903-4. 2008
    ..We hypothesized that an admission cervical spine CT with no acute injury-using new CT technology-is not sufficient for CS clearance in an unreliable patient...
  88. ncbi request reprint 'The hemostat wrap' a new technique in splenorraphy
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center and University of Maryland School of Medicine, Baltimore, 21201, USA
    J Trauma 59:1003-6. 2005
  89. doi request reprint Diagnosis and treatment of blunt thoracic aortic injuries: changing perspectives
    Demetrios Demetriades
    AAST Multi institutional Thoracic Aortic Injury Study Group, Los Angeles, California, USA
    J Trauma 64:1415-8; discussion 1418-9. 2008
    ..The present study compares clinical practices and results between an earlier prospective multicenter study by the American Association for the Surgery of Trauma completed in 1997 (AAST1) and a new similar study completed in 2007 (AAST2)...
  90. ncbi request reprint Incidence and impact of risk factors in critically ill trauma patients
    Grant V Bochicchio
    The R Adams Cowley Shock Trauma Center, Division of Clinical and Outcomes Research, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, Maryland 21201, USA
    World J Surg 30:114-8. 2006
    ..With our aging population it is becoming increasingly important to identify pre-existing risk factors on admission in order to minimize their effects on outcome...
  91. ncbi request reprint ATP accelerates respiration of mitochondria from rat lung and suppresses their release of hydrogen peroxide
    Drew E Carlson
    Program in Trauma and Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Bioenerg Biomembr 37:327-38. 2005
    ..Thus ATP-dependent processes that increase respiration appear to improve lung mitochondrial function while minimizing the release of reactive oxygen species...
  92. doi request reprint Operative repair or endovascular stent graft in blunt traumatic thoracic aortic injuries: results of an American Association for the Surgery of Trauma Multicenter Study
    Demetrios Demetriades
    J Trauma 64:561-70; discussion 570-1. 2008
    ....
  93. doi request reprint Blood product transfusion and ventilator-associated pneumonia in trauma patients
    Grant V Bochicchio
    Department of Surgery, R Adams Cowley Shock Trauma Center, Baltimore, Maryland 21201, USA
    Surg Infect (Larchmt) 9:415-22. 2008
    ..Prior studies in trauma are limited by retrospective design, lack of multivariable analyses, and scant data on the timing of transfusion. We examined critically the relation between blood product transfusion and VAP in trauma patients...
  94. doi request reprint Early hyperglycemic control is important in critically injured trauma patients
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center, Division of Clinical and Outcomes Research, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Trauma 63:1353-8; discussion 1358-9. 2007
    ..Our objectives were to determine whether persistent hyperglycemia when compared with normoglycemia was predictive of outcome in the later stages of hospitalization in critically injured trauma patients...
  95. ncbi request reprint Persistent hyperglycemia is predictive of outcome in critically ill trauma patients
    Grant V Bochicchio
    R Adams Cowley Shock Trauma Center, Baltimore, MD 21201, USA
    J Trauma 58:921-4. 2005
    ..Our objectives were to determine whether persistent hyperglycemia was predictive of outcome in critically ill trauma patients...
  96. doi request reprint Correlation of multidetector CT findings with splenic arteriography and surgery: prospective study in 392 patients
    Helen Marmery
    Nuffield Orthopaedic Centre, Windmill Road, Oxford, UK
    J Am Coll Surg 206:685-93. 2008
    ..To determine the accuracy of contrast-enhanced multidetector CT (MDCT) in demonstrating splenic vascular injury based on results of splenic angiography and operation...