Courtney L Scaife

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. pmc Prognostic significance of PINCH signalling in human pancreatic ductal adenocarcinoma
    Courtney L Scaife
    Department of Surgery, University of Utah, Salt Lake City, UT 84132, USA
    HPB (Oxford) 12:352-8. 2010
  2. ncbi request reprint Synthetic extracellular matrix enhances tumor growth and metastasis in an orthotopic mouse model of pancreatic adenocarcinoma
    Courtney L Scaife
    Department of Surgery, University of Utah, 30 North 1900 East, Salt Lake City, UT 84132, USA
    J Gastrointest Surg 12:1074-80. 2008
  3. pmc Ultrasonic nanotherapy of pancreatic cancer: lessons from ultrasound imaging
    Natalya Rapoport
    Department of Bioengineering, University of Utah, and Departments of Clinical Radiology and Surgery, School of Medicine, University of Utah, Salt Lake City, Utah 84112, USA
    Mol Pharm 7:22-31. 2010
  4. doi request reprint Natural history of pancreatic cancer recurrence following "curative" resection in athymic mice
    Marcus J Torgenson
    Department of Surgery, University of Utah, Salt Lake City, Utah 84132, USA
    J Surg Res 149:57-61. 2008
  5. pmc Serum osteopontin and tissue inhibitor of metalloproteinase 1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Pancreas 42:193-7. 2013
  6. pmc Genexol inhibits primary tumour growth and metastases in gemcitabine-resistant pancreatic ductal adenocarcinoma
    Jill E Shea
    Department of Surgery, School of Medicine, University of Utah, Salt Lake City, UT 84132, USA
    HPB (Oxford) 13:153-7. 2011
  7. pmc Serum platelet factor 4 is an independent predictor of survival and venous thromboembolism in patients with pancreatic adenocarcinoma
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Cancer Epidemiol Biomarkers Prev 19:2605-10. 2010
  8. pmc Phenotype and genotype of pancreatic cancer cell lines
    Emily L Deer
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Pancreas 39:425-35. 2010
  9. pmc Exploiting antitumor immunity to overcome relapse and improve remission duration
    Lei L Chen
    Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, USA
    Cancer Immunol Immunother 61:1113-24. 2012
  10. ncbi request reprint Effects of trastuzumab on epidermal growth factor receptor-dependent and -independent human colon cancer cells
    Scott K Kuwada
    Department of Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA
    Int J Cancer 109:291-301. 2004

Collaborators

Detail Information

Publications24

  1. pmc Prognostic significance of PINCH signalling in human pancreatic ductal adenocarcinoma
    Courtney L Scaife
    Department of Surgery, University of Utah, Salt Lake City, UT 84132, USA
    HPB (Oxford) 12:352-8. 2010
    ..Recently, interest has developed in the accuracy of integrin-associated PINCH protein expression in human cancers as a predictive marker of tumour status. The goal of this study was to define the expression of PINCH protein in PDA...
  2. ncbi request reprint Synthetic extracellular matrix enhances tumor growth and metastasis in an orthotopic mouse model of pancreatic adenocarcinoma
    Courtney L Scaife
    Department of Surgery, University of Utah, 30 North 1900 East, Salt Lake City, UT 84132, USA
    J Gastrointest Surg 12:1074-80. 2008
    ..The advantages of this new approach can be utilized to investigate the mechanisms of tumor progression and test novel therapeutic agents in vivo...
  3. pmc Ultrasonic nanotherapy of pancreatic cancer: lessons from ultrasound imaging
    Natalya Rapoport
    Department of Bioengineering, University of Utah, and Departments of Clinical Radiology and Surgery, School of Medicine, University of Utah, Salt Lake City, Utah 84112, USA
    Mol Pharm 7:22-31. 2010
    ..This is implicated as a possible cause of the resistance development, which may be pertinent to various modes of tumor nanotherapy...
  4. doi request reprint Natural history of pancreatic cancer recurrence following "curative" resection in athymic mice
    Marcus J Torgenson
    Department of Surgery, University of Utah, Salt Lake City, Utah 84132, USA
    J Surg Res 149:57-61. 2008
    ..Following "curative" pancreatic resection, we demonstrate postoperative disease recurrence by fluorescence imaging...
  5. pmc Serum osteopontin and tissue inhibitor of metalloproteinase 1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Pancreas 42:193-7. 2013
    ..We assessed serum osteopontin (OPN) and tissue inhibitor of metalloproteinase 1 (TIMP-1) as possible diagnostic and prognostic biomarkers in a novel cohort of patients with pancreatic cancer...
  6. pmc Genexol inhibits primary tumour growth and metastases in gemcitabine-resistant pancreatic ductal adenocarcinoma
    Jill E Shea
    Department of Surgery, School of Medicine, University of Utah, Salt Lake City, UT 84132, USA
    HPB (Oxford) 13:153-7. 2011
    ..The aim of the present study was to determine if Genexol would be a beneficial treatment for gemcitabine-resistant PDA...
  7. pmc Serum platelet factor 4 is an independent predictor of survival and venous thromboembolism in patients with pancreatic adenocarcinoma
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Cancer Epidemiol Biomarkers Prev 19:2605-10. 2010
    ..Platelet factor 4 (PF4) has been proposed as a diagnostic biomarker for PDAC. We assessed the diagnostic and prognostic potential of serum PF4 levels in PDAC patients...
  8. pmc Phenotype and genotype of pancreatic cancer cell lines
    Emily L Deer
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Pancreas 39:425-35. 2010
    ..Identification of both consensus and discrepant information in the literature suggests careful evaluation before selection of cell lines and attention be given to cell line authentication...
  9. pmc Exploiting antitumor immunity to overcome relapse and improve remission duration
    Lei L Chen
    Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, USA
    Cancer Immunol Immunother 61:1113-24. 2012
    ....
  10. ncbi request reprint Effects of trastuzumab on epidermal growth factor receptor-dependent and -independent human colon cancer cells
    Scott K Kuwada
    Department of Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA
    Int J Cancer 109:291-301. 2004
    ..Predicting clinical responsiveness of human colon cancer cells to anti-HER-2 and anti-EGFR therapy may require demonstration of EGFR tyrosine kinase dependency of the cells...
  11. doi request reprint A comparison of postoperative outcomes utilizing a continuous preperitoneal infusion versus epidural for midline laparotomy
    Molly E Gross
    Department of Surgery, University of Utah, Salt Lake City, UT, USA
    Am J Surg 202:765-9; discussion 770. 2011
    ..This is the first direct comparison of CPI versus epidural infusion (EPI), both in conjunction with systemic analgesia...
  12. doi request reprint Does travel distance influence length of stay in elective colorectal surgery?
    Katharine L Jackson
    Department of Surgery, University of Utah, Salt Lake City, UT 84132, USA
    Dis Colon Rectum 56:367-73. 2013
    ..Regional referral centers with large geographic catchment areas attract patients from significant distances...
  13. pmc Improved diagnosis of pancreatic adenocarcinoma using haptoglobin and serum amyloid A in a panel screen
    Matthew A Firpo
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    World J Surg 33:716-22. 2009
    ....
  14. pmc Controlled and targeted tumor chemotherapy by ultrasound-activated nanoemulsions/microbubbles
    Natalya Y Rapoport
    Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA
    J Control Release 138:268-76. 2009
    ....
  15. pmc Roux-en-Y drainage of a pancreatic fistula for disconnected pancreatic duct syndrome after acute necrotizing pancreatitis
    Erik G Pearson
    Department of Surgery, University of Utah, Salt Lake City, 84132, USA
    HPB (Oxford) 14:26-31. 2012
    ..After acute necrotizing pancreatitis (ANP), a pancreatic fistula may occur from disconnected pancreatic duct syndrome (DPDS) where a segment of the pancreas is no longer in continuity with the main pancreatic duct...
  16. doi request reprint Evolution from heterozygous to homozygous KIT mutation in gastrointestinal stromal tumor correlates with the mechanism of mitotic nondisjunction and significant tumor progression
    Lei L Chen
    Department of Internal Medicine, Division of Hematology Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
    Mod Pathol 21:826-36. 2008
    ....
  17. ncbi request reprint Intraoperative radiotherapy in the multimodality approach to gastric cancer
    Courtney L Scaife
    University of Utah Cancer Institute, Salt Lake City, Utah 84103, USA
    Surg Oncol Clin N Am 12:955-64. 2003
    ....
  18. pmc Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas
    Daniel Kopinke
    Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
    Development 138:431-41. 2011
    ..Together, these studies clarify the roles of Notch and Hes1 in the developing and adult pancreas, and open new avenues to study Notch signaling in this and other tissues...
  19. doi request reprint Antibiotic prophylaxis in the placement of totally implanted central venous access ports
    Courtney L Scaife
    Department of Surgery, University of Utah, East Salt Lake City, UT 84132, USA
    Am J Surg 200:719-22; disussion 722-3. 2010
    ..Antibiotic prophylaxis during placement of implanted central venous access ports (CVAP) has not been studied. This retrospective review compared the rate of catheter-related infections (CRIs) with and without perioperative antibiotics...
  20. ncbi request reprint Nuclear factor kappaB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis
    Courtney L Scaife
    Department of Surgery, Salt Lake City Veterans Administration Medical Center, and University of Utah, Salt Lake City, Utah 84132, USA
    Cancer Res 62:6870-8. 2002
    ..The ability of soluble NFkappaB inhibitors to significantly induce apoptosis of readherent colon cancer cells makes them prospective candidates for preventing colon cancer metastasis...
  21. ncbi request reprint Surgical resection of gastrointestinal stromal tumors after treatment with imatinib
    Robert H I Andtbacka
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Unit 444, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Ann Surg Oncol 14:14-24. 2007
    ..In this study, the surgical resection rates and long-term outcomes of patients treated with preoperative imatinib for locally advanced primary, recurrent, or metastatic GISTs were evaluated...
  22. ncbi request reprint Lynch syndrome: implications for the surgeon
    Courtney L Scaife
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Clin Colorectal Cancer 3:92-8. 2003
    ..In this article, the diagnosis and management of Lynch syndrome will be reviewed, with emphasis on the implications for the surgeon...
  23. ncbi request reprint Is there a role for surgery in patients with "unresectable" cKIT+ gastrointestinal stromal tumors treated with imatinib mesylate?
    Courtney L Scaife
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Am J Surg 186:665-9. 2003
    ..This retrospective review of patients with cKIT+ GISTs who received Gleevec prior to surgical resection examines the pathologic response to therapy and the feasibility of surgical resection after treatment...
  24. ncbi request reprint Complication, local recurrence, and survival rates after radiofrequency ablation for hepatic malignancies
    Courtney L Scaife
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Box 444, Houston, TX 77030, USA
    Surg Oncol Clin N Am 12:243-55. 2003
    ..Improved technology and concurrent application of RFA with other treatment modalities should continue to improve tumor response and patient survival for patients with unresectable hepatic malignancies...