J A Saxton
Affiliation: University of Pittsburgh
- Cognitive test performance and presence of subclinical cardiovascular disease in the cardiovascular health studyJ Saxton
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Neuroepidemiology 19:312-9. 2000..These results add to the evidence that, in addition to other health implications, cardiovascular disease is related to cognitive functioning in the elderly even at subclinical levels...
- Normative data on the Boston Naming Test and two equivalent 30-item short formsJ Saxton
Western Psychiatric Institute and Clinic, University of Pittsburgh, PA 15213, USA
Clin Neuropsychol 14:526-34. 2000..Age and education norms are presented using an overlapping midpoint interval strategy...
- Speed and capacity of language processing test: normative data from an older American community-dwelling sampleJ A Saxton
Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA
Appl Neuropsychol 8:193-203. 2001..By contrast, increasing age has little effect on lexical decision. Thus, our data suggest that the SCOLP shows promise as a tool to help distinguish between normal aging and the early stages of dementia...
- Preclinical Alzheimer disease: neuropsychological test performance 1.5 to 8 years prior to onsetJ Saxton
University of Pittsburgh, Oxford Building, Room 738, Pittsburgh, PA 15213, USA
Neurology 63:2341-7. 2004..To determine if individuals ultimately diagnosed with Alzheimer disease (AD) exhibited evidence of cognitive impairment on neuropsychological tests administered between 1.5 years and 8.1 years before dementia onset...
- Sex differences in brain aging: a quantitative magnetic resonance imaging studyC E Coffey
Department of Psychiatry, Henry Ford Health System, Detroit, Mich 48202, USA
Arch Neurol 55:169-79. 1998..Little is known about the effect of sex on age-related changes in brain structure...
- Alcohol consumption and cognitive function in late life: a longitudinal community studyM Ganguli
Division of Geriatrics and Neuropsychiatry, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Neurology 65:1210-7. 2005..To examine the association between alcohol use and cognitive decline in a longitudinal study of a representative elderly community sample free of dementia at baseline...
- Serum anticholinergic activity, white matter hyperintensities, and cognitive performanceR D Nebes
Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Neurology 65:1487-9. 2005....
- Relation of education to brain size in normal aging: implications for the reserve hypothesisC E Coffey
Department of Psychiatry, Henry Ford Health System, Detroit, MI 48202, USA
Neurology 53:189-96. 1999..To examine the relations between education and age-related changes in brain structure in a nonclinical sample of elderly adults...
- The relation of white matter hyperintensities to cognitive performance in the normal old: education mattersRobert D Nebes
University of Pittsburgh Medical Center, Pennsylvania, USA
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn 13:326-40. 2006..This is consistent with recent concepts of cognitive reserve, but does raise a question as to the underlying source of the cognitive decrement found in the sort of well-educated elders typically used in cognitive-aging studies...
- Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigreesWilliam E Klunk
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
J Neurosci 27:6174-84. 2007..The early, focal striatal amyloid deposition observed in these PS1 mutation carriers is often is not associated with clinical symptoms...
- The association between congestive heart failure and cognitive performance in a primary care population of elderly adults: the Steel Valley Seniors SurveyLaurie Lavery
Division of Geriatric Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Int Psychogeriatr 19:215-25. 2007..We examined the association between CHF and cognitive performance in stable outpatients recruited from primary care...
- Event-related functional magnetic resonance imaging investigation of executive control in very old individuals with mild cognitive impairmentCaterina Rosano
School of Public Health, Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 57:761-7. 2005..76, p = .02) but not with changes in accuracy rates. CONCLUSIONS: PPC and dlPFC may show early functional changes associated with MCI...
- Alzheimer disease with psychosis: excess cognitive impairment is restricted to the misidentification subtypeGina Perez-Madriñan
Dept of Psychiatry, Univ of Pittsburgh, PA, USA
Am J Geriatr Psychiatry 12:449-56. 2004..We hypothesized that these two groups differed in their patterns of cognitive impairment, compared with AD subjects without psychosis...
- Characterizing regional correlation, laterality and symmetry of amyloid deposition in mild cognitive impairment and Alzheimer's disease with Pittsburgh Compound BCyrus A Raji
Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2593, United States
J Neurosci Methods 172:277-82. 2008..02, p=0.01) and anterior ventral striatum [t(9)=2.37, p=0.04] in AD. No group differences (AD versus MCI) were detected in laterality [F (1, 15)=0.15, p=0.7] or asymmetry [F (1, 15)=0.7, p=0.42]...
- Cognitive domains and trajectories of functional independence in nondemented elderly personsHiroko H Dodge
Department of Public Health, Oregon State University, Corvallis, OR 97331, USA
J Gerontol A Biol Sci Med Sci 61:1330-7. 2006..Cognitive impairment in general is known to predict functional disability, but it is not clear whether performance on specific cognitive domains predicts future disability trends among nondemented elderly persons...