J R Sawyer

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. ncbi request reprint Multicolour spectral karyotyping identifies new translocations and a recurring pathway for chromosome loss in multiple myeloma
    J R Sawyer
    Myeloma and Transplantation Research Center, Arkansas Cancer Research Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Br J Haematol 112:167-74. 2001
  2. ncbi request reprint Molecular cytogenetic analysis of a medulloblastoma with isochromosome 17 and double minutes
    J R Sawyer
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock
    Cancer Genet Cytogenet 57:181-6. 1991
  3. ncbi request reprint Cyclin D1 and E2F-1 immunoreactivity in bone marrow biopsy specimens of multiple myeloma: relationship to proliferative activity, cytogenetic abnormalities and DNA ploidy
    C S Wilson
    University of Arkansas for Medical Sciences, Department of Pathology, Mail Slot 502, 4301 West Markham Street, Little Rock, AR 72205, USA
    Br J Haematol 112:776-82. 2001
  4. pmc Mitochondrial DNA determines androgen dependence in prostate cancer cell lines
    M Higuchi
    Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205 7199, USA
    Oncogene 25:1437-45. 2006

Detail Information

Publications4

  1. ncbi request reprint Multicolour spectral karyotyping identifies new translocations and a recurring pathway for chromosome loss in multiple myeloma
    J R Sawyer
    Myeloma and Transplantation Research Center, Arkansas Cancer Research Center, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Br J Haematol 112:167-74. 2001
    ..The chromosome instability identified here demonstrates that the loss of 8p can occur by multiple whole-arm translocations, indicating a new pathway for the loss of a specific chromosome region in MM...
  2. ncbi request reprint Molecular cytogenetic analysis of a medulloblastoma with isochromosome 17 and double minutes
    J R Sawyer
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock
    Cancer Genet Cytogenet 57:181-6. 1991
    ..The finding of double minute chromosomes in some medulloblastomas has been associated with amplification of the c-myc or N-myc oncogenes. We were unable to detect gene amplification with these probes by Southern blot analysis...
  3. ncbi request reprint Cyclin D1 and E2F-1 immunoreactivity in bone marrow biopsy specimens of multiple myeloma: relationship to proliferative activity, cytogenetic abnormalities and DNA ploidy
    C S Wilson
    University of Arkansas for Medical Sciences, Department of Pathology, Mail Slot 502, 4301 West Markham Street, Little Rock, AR 72205, USA
    Br J Haematol 112:776-82. 2001
    ..We conclude that in low to intermediately proliferative MM cases, cyclin D1 is probably upregulated by t(11;14), but an alternative mechanism is more probable in highly proliferative MM...
  4. pmc Mitochondrial DNA determines androgen dependence in prostate cancer cell lines
    M Higuchi
    Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205 7199, USA
    Oncogene 25:1437-45. 2006
    ..The accumulation of large deletion and depletion of mitochondrial DNA may thus play a role in the development of androgen independence, leading to progression of prostate cancers...