Daniel Savic

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. pmc An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers
    Daniel Savic
    Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 7:e36501. 2012
  2. pmc Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism
    Daniel Savic
    Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA
    Genome Res 21:1417-25. 2011
  3. pmc Modulation ofTcf7l2 expression alters behavior in mice
    Daniel Savic
    Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 6:e26897. 2011
  4. pmc Transcriptional enhancers in development and disease
    Noboru Jo Sakabe
    Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA
    Genome Biol 13:238. 2012

Collaborators

Detail Information

Publications4

  1. pmc An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers
    Daniel Savic
    Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 7:e36501. 2012
    ..These results highlight the regulatory complexity of this interval and support the notion that a TCF7L2 cis-regulatory disruption leads to T2D predisposition...
  2. pmc Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism
    Daniel Savic
    Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA
    Genome Res 21:1417-25. 2011
    ..These data highlight the role of enhancer elements as mediators of T2D risk in humans, strengthening the evidence that variation in cis-regulatory elements may be a paradigm for genetic predispositions to common disease...
  3. pmc Modulation ofTcf7l2 expression alters behavior in mice
    Daniel Savic
    Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America
    PLoS ONE 6:e26897. 2011
    ..These animal models have the potential to elucidate the molecular basis of psychiatric comorbidities in diabetes and should therefore be studied further...
  4. pmc Transcriptional enhancers in development and disease
    Noboru Jo Sakabe
    Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA
    Genome Biol 13:238. 2012
    ..Because of their importance, their disruption can lead to disease...