Edward R Sauter

Summary

Affiliation: University of North Dakota
Country: USA

Publications

  1. pmc Skin necrosis in smoking patients receiving partial breast irradiation: two case reports
    Edward R Sauter
    Departments of Surgery ERS, JT and Radiology SW, Ellis Fischel Cancer Center, Columbia, MO 65212, USA
    Cases J 1:230. 2008
  2. pmc Identification of a beta-casein-like peptide in breast nipple aspirate fluid that is associated with breast cancer
    Edward R Sauter
    Department of Surgery, University of North Dakota School of Medicine and Health Sciences, 501 N Columbia Road, Stop 9037, Grand Forks, ND 58201, USA
    Biomark Med 3:577-88. 2009
  3. pmc Circulating microRNAs in breast cancer and healthy subjects
    Weizhu Zhu
    Department of Surgery, University of North Dakota, Grand Forks, ND, USA
    BMC Res Notes 2:89. 2009
  4. pmc Nipple aspirate fluid and ductoscopy to detect breast cancer
    Edward R Sauter
    Department of Surgery, University of North Dakota, Grand Forks, North Dakota 58203, USA
    Diagn Cytopathol 38:244-51. 2010
  5. pmc uPA is upregulated by high dose celecoxib in women at increased risk of developing breast cancer
    Wenyi Qin
    Department of Surgery, University of North Dakota, Grand Forks, ND, USA
    BMC Cancer 8:298. 2008
  6. doi Biomarkers associated with breast cancer are associated with obesity
    Edward R Sauter
    Department of Surgery, University of Missouri, One Hospital Drive, Columbia, MO 65212, USA
    Cancer Detect Prev 32:149-55. 2008
  7. pmc Proteins and carbohydrates in nipple aspirate fluid predict the presence of atypia and cancer in women requiring diagnostic breast biopsy
    Wenyi Qin
    Department of Surgery, University of North Dakota School of Medicine and Health Sciences, 501 N Columbia Rd, Grand Forks, ND 58202, USA
    BMC Cancer 12:52. 2012
  8. pmc Celecoxib concentration predicts decrease in prostaglandin E2 concentrations in nipple aspirate fluid from high risk women
    Edward R Sauter
    Department of Surgery, University of Missouri, Columbia, MO, USA
    BMC Cancer 8:49. 2008
  9. pmc Celecoxib decreases prostaglandin E2 concentrations in nipple aspirate fluid from high risk postmenopausal women and women with breast cancer
    Edward R Sauter
    Surgery, University of Missouri, Columbia, MO 65212, USA
    BMC Cancer 6:248. 2006
  10. pmc Trans-resveratrol alters mammary promoter hypermethylation in women at increased risk for breast cancer
    Weizhu Zhu
    Departments of Surgery and Pathology, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58202, USA
    Nutr Cancer 64:393-400. 2012

Collaborators

Detail Information

Publications53

  1. pmc Skin necrosis in smoking patients receiving partial breast irradiation: two case reports
    Edward R Sauter
    Departments of Surgery ERS, JT and Radiology SW, Ellis Fischel Cancer Center, Columbia, MO 65212, USA
    Cases J 1:230. 2008
    ..Early reports suggest good to excellent cosmesis in the vast majority of subjects. Herein we report two cases of skin necrosis in women with Stage 1 breast cancer who smoked before and after partial breast irradiation...
  2. pmc Identification of a beta-casein-like peptide in breast nipple aspirate fluid that is associated with breast cancer
    Edward R Sauter
    Department of Surgery, University of North Dakota School of Medicine and Health Sciences, 501 N Columbia Road, Stop 9037, Grand Forks, ND 58201, USA
    Biomark Med 3:577-88. 2009
    ..Combining proteomic and clinical information, which are available before surgery, optimizes the prediction of which women have breast cancer...
  3. pmc Circulating microRNAs in breast cancer and healthy subjects
    Weizhu Zhu
    Department of Surgery, University of North Dakota, Grand Forks, ND, USA
    BMC Res Notes 2:89. 2009
    ..Screening serum for miRNAs that predict the presence of breast cancer is feasible, and may be useful for breast cancer detection...
  4. pmc Nipple aspirate fluid and ductoscopy to detect breast cancer
    Edward R Sauter
    Department of Surgery, University of North Dakota, Grand Forks, North Dakota 58203, USA
    Diagn Cytopathol 38:244-51. 2010
    ..The presence of atypical cells arising from an intraductal papilloma in ductoscopic specimens is a potential source of false positive diagnosis in patients with nipple discharge...
  5. pmc uPA is upregulated by high dose celecoxib in women at increased risk of developing breast cancer
    Wenyi Qin
    Department of Surgery, University of North Dakota, Grand Forks, ND, USA
    BMC Cancer 8:298. 2008
    ....
  6. doi Biomarkers associated with breast cancer are associated with obesity
    Edward R Sauter
    Department of Surgery, University of Missouri, One Hospital Drive, Columbia, MO 65212, USA
    Cancer Detect Prev 32:149-55. 2008
    ..It was our hypothesis that proteins associated with breast cancer would be associated with body mass index (BMI)...
  7. pmc Proteins and carbohydrates in nipple aspirate fluid predict the presence of atypia and cancer in women requiring diagnostic breast biopsy
    Wenyi Qin
    Department of Surgery, University of North Dakota School of Medicine and Health Sciences, 501 N Columbia Rd, Grand Forks, ND 58202, USA
    BMC Cancer 12:52. 2012
    ..The second study assessed if these proteins increased the predictive ability of a carbohydrate (Thomsen Friedenreich, TF) which we previously demonstrated predicted the presence of disease in postmenopausal women requiring surgery...
  8. pmc Celecoxib concentration predicts decrease in prostaglandin E2 concentrations in nipple aspirate fluid from high risk women
    Edward R Sauter
    Department of Surgery, University of Missouri, Columbia, MO, USA
    BMC Cancer 8:49. 2008
    ....
  9. pmc Celecoxib decreases prostaglandin E2 concentrations in nipple aspirate fluid from high risk postmenopausal women and women with breast cancer
    Edward R Sauter
    Surgery, University of Missouri, Columbia, MO 65212, USA
    BMC Cancer 6:248. 2006
    ..The endpoints of the current study were to determine if a short course of celecoxib 400 mg bid would decrease PGE2 levels in women 1) at increased breast cancer risk, and 2) with established breast cancer...
  10. pmc Trans-resveratrol alters mammary promoter hypermethylation in women at increased risk for breast cancer
    Weizhu Zhu
    Departments of Surgery and Pathology, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58202, USA
    Nutr Cancer 64:393-400. 2012
    ..Because of the limited sample size, our findings should be validated in a larger study...
  11. pmc Soy isoflavones have an antiestrogenic effect and alter mammary promoter hypermethylation in healthy premenopausal women
    Wenyi Qin
    Department of Surgery, University of Missouri School of Medicine Columbia, One Hospital Drive, Columbia, MO 65212, USA
    Nutr Cancer 61:238-44. 2009
    ..Isoflavones induced dose-specific changes in RARbeta2 and CCND2 gene methylation, which correlated with genistein levels. This work provides novel insights into estrogenic and methylation effects of dietary isoflavones...
  12. pmc Biologic markers of breast cancer in nipple aspirate fluid and nipple discharge are associated with clinical findings
    Edward R Sauter
    Department of Surgery, Ellis Fischel Cancer Center at the University of Missouri, Columbia, One Hospital Drive, Columbia, MO 65212, United States
    Cancer Detect Prev 31:50-8. 2007
    ....
  13. doi Differential expression of cancer-associated proteins in breastmilk
    Wenyi Qin
    Department of Surgery, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58202, USA
    Breastfeed Med 8:120-6. 2013
    ..Total milk protein concentration is lower in the mid and late phases of nursing. Biomarker differences between T and W milk samples in KLK6, TGFβ2, and bFGF are consistent with a protective effect of nursing...
  14. ncbi Fiberoptic ductoscopy findings in women with and without spontaneous nipple discharge
    Edward R Sauter
    Department of Surgery, University of Missouri Columbia Ellis Fischel Cancer Center, Columbia, Missouri 65212, USA
    Cancer 103:914-21. 2005
    ....
  15. ncbi Nipple aspirate fluid expression of urokinase-type plasminogen activator, plasminogen activator inhibitor-1, and urokinase-type plasminogen activator receptor predicts breast cancer diagnosis and advanced disease
    Wenyi Qin
    Department of Surgery, University of Missouri, Columbia, Missouri 65212, USA
    Ann Surg Oncol 10:948-53. 2003
    ..We determined the association of uPA, PAI-1, and uPAR levels in NAF with breast cancer (1) detection and (2) advanced disease...
  16. ncbi Prospective multicenter trial to determine the feasibility of collection and predictive ability of breast fluid analysis in postmenopausal women receiving SERMs
    Edward R Sauter
    Department of Surgery, University of Missouri Columbia, One Hospital Drive, Rm N510, Columbia, MO 65212, USA
    Breast 16:489-94. 2007
    ..Multiinstitutional clinical trials in postmenopausal women using NAF biomarkers as the primary endpoints are feasible...
  17. ncbi Increased expression of the inflammatory protein YKL-40 in precancers of the breast
    Wenyi Qin
    Department of Surgery University of Missouri, Columbia, MO 65121, USA
    Int J Cancer 121:1536-42. 2007
    ..NAF levels of YKL-40 are significantly higher in women with precancers than healthy subjects, suggesting that measuring YKL-40 in NAF may improve the identification of women at increased breast cancer risk...
  18. pmc Quantitative evaluation of DNA hypermethylation in malignant and benign breast tissue and fluids
    Weizhu Zhu
    Department of Research Affairs, University of North Dakota, Grand Forks, USA
    Int J Cancer 126:474-82. 2010
    ....
  19. ncbi Thomsen-Friedenreich and Tn antigens in nipple fluid: carbohydrate biomarkers for breast cancer detection
    Senthil R Kumar
    Department of Biochemistry, University of Missouri, Columbia, Missouri 65212, USA
    Clin Cancer Res 11:6868-71. 2005
    ..A sensitive and specific antigen capture immunoassay for TF and Tn detection in NAF was developed for this purpose...
  20. ncbi Prostate-specific antigen expression in nipple aspirate fluid is associated with advanced breast cancer
    Edward R Sauter
    Department of Surgery, University of Missouri Columbia, M588 Health Sciences Center, One Hospital Drive, Columbia, MO 65212, USA
    Cancer Detect Prev 28:27-31. 2004
    ..009), nodal status (P = 0.005), disease stage (P = 0.004), and distant metastases (P = 0.04). NAF PSA provides useful prognostic information which may assist with breast cancer treatment...
  21. doi Can mitochondrial DNA mutations in circulating white blood cells and serum be used to detect breast cancer?
    Julian E Losanoff
    Department of Surgery, John D Dingell VAMC and Wayne State University, Detroit, MI, USA
    Breast 17:540-2. 2008
    ..The method used did not detect mtDNA mutations in the blood of women with breast cancer, but was extremely sensitive in polymorphism detection...
  22. pmc Differential expression of cancer associated proteins in breast milk based on age at first full term pregnancy
    Wenyi Qin
    Department of Surgery, University of North Dakota School of Medicine and Health Sciences, 501 N Columbia Rd, Grand Forks, ND 58202, USA
    BMC Cancer 12:100. 2012
    ..Our hypothesis was that proteins linked to breast cancer would be differentially expressed in human milk collected at three time points during lactation based on age at FFTP...
  23. pmc Carbohydrate antigens in nipple aspirate fluid predict the presence of atypia and cancer in women requiring diagnostic breast biopsy
    Susan L Deutscher
    University of Missouri, Department of Biochemistry, One Hospital Drive, Columbia, MO 65212, USA
    BMC Cancer 10:519. 2010
    ....
  24. ncbi Ductoscopic cytology and image analysis to detect breast carcinoma
    Edward R Sauter
    Department of Surgery, University of Missouri Columbia Ellis Fischel Cancer Center, 65212, USA
    Cancer 101:1283-92. 2004
    ....
  25. pmc α1-adrenergic receptors positively regulate Toll-like receptor cytokine production from human monocytes and macrophages
    Laurel A Grisanti
    Department of Pharmacology, Physiology, and Therapeutics, University of North Dakota School of Medicine and Health Sciences, 501 North Columbia Road, Grand Forks, ND 58202 9037, USA
    J Pharmacol Exp Ther 338:648-57. 2011
    ..This study characterizes α(1)-AR subtype expression on both human monocyte and macrophage cells and illustrates a mechanism by which increased IL-1β production can be modulated by α(1)-AR input...
  26. ncbi Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid
    Weizhu Zhu
    Ellis Fischel Cancer Center, Department of Surgery, University of Missouri, Columbia, MO 65212, USA
    Carcinogenesis 26:145-52. 2005
    ..The high frequency of mtDNA mutations at polymorphic loci requires further investigation. Specific mtDNA mutations can be detected in a subset of NAF samples from women with breast cancer...
  27. ncbi Proteomic analysis to identify breast cancer biomarkers in nipple aspirate fluid
    Hannah Alexander
    Division of Biological Sciences, and Department of Surgery, University of Missouri, Columbia, Missouri 65212, USA
    Clin Cancer Res 10:7500-10. 2004
    ....
  28. ncbi Black cohosh does not exert an estrogenic effect on the breast
    Rachel L Ruhlen
    Department of Surgery, University of Missouri Columbia, Columbia, MO 65212, USA
    Nutr Cancer 59:269-77. 2007
    ..Triterpene content in commercially available black cohosh preparations varies. BCE standardized to 2.5% triterpenes relieved menopausal symptoms without systemic or breast-specific estrogenic effects...
  29. ncbi Proteomic analysis of nipple aspirate fluid using SELDI-TOF-MS
    Edward R Sauter
    Department of Surgery, University of Missouri Columbia, Columbia, MO 65212, USA
    Int J Cancer 114:791-6. 2005
    ....
  30. ncbi Ductoscopic cytology to detect breast cancer
    Edward R Sauter
    Department of Surgery, University of Missouri Columbia Ellis Fischel Cancer Center, Columbia, Missouri 65212, USA
    Cancer J 10:33-41; discussion 15-6. 2004
    ....
  31. ncbi Nipple aspirate fluid color is associated with breast cancer
    Edward R Sauter
    Department of Surgery, University of Missouri Columbia, N510 Health Sciences Center, One Hospital Drive, Columbia, MO 65212, United States
    Cancer Detect Prev 30:322-8. 2006
    ....
  32. ncbi The association of bloody nipple discharge with breast pathology
    Edward R Sauter
    Department of Surgery, University of Missouri Columbia Ellis Fischel Cancer Center, Columbia MO 65212, USA
    Surgery 136:780-5. 2004
    ....
  33. pmc Tamoxifen induces regression of estradiol-induced mammary cancer in the ACI.COP-Ept2 rat model
    Rachel L Ruhlen
    Department of Surgery, University of Missouri Columbia, One Hospital Drive, Rm N510, Columbia, MO 65212, USA
    Breast Cancer Res Treat 117:517-24. 2009
    ..ERalpha and PR were overexpressed in tumor compared to adjacent non-tumor mammary gland. Thus, this model is highly relevant to hormone responsive human breast cancers...
  34. ncbi Association of kallikrein expression in nipple aspirate fluid with breast cancer risk
    Edward R Sauter
    Department of Surgery, University of Missouri, Columbia, MO 65212, USA
    Int J Cancer 108:588-91. 2004
    ..hK2 and PSA, and hK6 and hK10 are highly associated. Higher premenopausal PSA levels suggest the influence of ovarian steroids. PSA shows the most promise in aiding in the early detection of breast cancer...
  35. ncbi Analysis of nipple aspirate fluid for diagnosis of breast cancer: an alternative to invasive biopsy
    Edward R Sauter
    University of Missouri, One Hospital Drive, Columbia, MO 65212, USA
    Expert Rev Mol Diagn 5:873-81. 2005
    ..Herein, the technology is reviewed as it was, as it is today, and its future potential is discussed...
  36. ncbi Large-scale mitochondrial DNA deletion mutations and nuclear genome instability in human breast cancer
    Weizhu Zhu
    Ellis Fischel Cancer Center and Department of Surgery, University of Missouri, M588 One Hospital Drive, Columbia, MO 65212, USA
    Cancer Detect Prev 28:119-26. 2004
    ....
  37. ncbi Lack of effect of celecoxib on prostaglandin E2 concentrations in nipple aspirate fluid from women at increased risk of breast cancer
    Edward R Sauter
    Department of Surgery, University of Missouri Columbia, One Hospital Drive, Room M588, Columbia, MO 65212, USA
    Cancer Epidemiol Biomarkers Prev 13:1745-50. 2004
    ..Among these, prostaglandin E(2) (PGE(2)) has tumor growth-promoting activity. The COX-2 isoform is the primary enzyme involved in PGE(2) production in cancerous tissue...
  38. doi Calcium homeostasis and bone metabolic responses to high-protein diets during energy deficit in healthy young adults: a randomized controlled trial
    Jay J Cao
    USDA, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND JJC, LDW, and GFC the Military Nutrition Division, US Army Research Institute of Environmental Medicine, Natick, MA SMP, LMM, JPM, and AJY and the School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND ERS
    Am J Clin Nutr 99:400-7. 2014
    ..Although consuming dietary protein above current recommendations during energy deficit (ED) preserves lean body mass, concerns have been raised regarding the effects of high-protein diets on bone health...
  39. doi Cancer prevention and treatment using combination therapy with plant- and animal-derived compounds
    Jacinta Uzoigwe
    University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND, USA
    Expert Rev Clin Pharmacol 5:701-9. 2012
    ..When the data warrant it, combined (pharmacologic and natural; two or more natural) interventions that appear to increase efficacy (compared with monotherapy) while minimizing toxicity have been highlighted...
  40. doi Total dietary fat and fatty acid content modifies plasma phospholipid fatty acids, desaturase activity indices, and urinary prostaglandin E in women
    Susan K Raatz
    ARS, USDA, Human Nutrition Research Center, Grand Forks, ND 58203, USA
    Nutr Res 32:1-7. 2012
    ....
  41. ncbi Radionuclide-peptide nucleic acid in diagnosis and treatment of pancreatic cancer
    Eric Wickstrom
    Department of Biochemistry, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA
    Methods Mol Med 106:135-91. 2005
  42. pmc Serum Müllerian inhibiting substance levels are lower in premenopausal women with breast precancer and cancer
    Andrew C McCoy
    Department of Surgery, University of North Dakota School of Medicine, Grand Forks, ND, USA
    BMC Res Notes 4:152. 2011
    ..abstract:..
  43. doi Breast cancer after severe burn injury: coincidence or consequence?
    Julian E Losanoff
    Department of Surgery, John D Dingell VAMC and Wayne State University, Detroit, Michigan, USA
    Breast J 14:87-9. 2008
    ..Breast lesions in this or a similar clinical scenario should be considered malignant until proven otherwise, and a tissue diagnosis must be pursued without delay...
  44. ncbi Association of uPA, PAT-1, and uPAR in nipple aspirate fluid (NAF) with breast cancer
    Wenyi Qin
    Department of Surgery, University of Missouri, Columbia, Missouri 65212, USA
    Cancer J 9:293-301. 2003
    ....
  45. ncbi Ethnic variation in kallikrein expression in nipple aspirate fluid
    Edward R Sauter
    Department of Surgery, Thomas Jefferson University, 1025 Walnut Street, Suite 605, Philadelphia, PA 19107, USA
    Int J Cancer 100:678-82. 2002
    ....
  46. pmc Breast cancer biomarkers predict weight loss after gastric bypass surgery
    Edward R Sauter
    Departments of Surgery, University of North Dakota School of Medicine and Health Sciences, 501 N, Columbia Rd, Grand Forks, ND 58202, USA
    BMC Res Notes 5:82. 2012
    ..abstract:..
  47. doi Proteomics of nipple aspirate fluid, breast cyst fluid, milk, and colostrum
    Rachel L Ruhlen
    Department of Surgery, University of Missouri, Columbia, MO, USA
    Proteomics Clin Appl 1:845-52. 2007
    ..A better understanding of the protein composition of milk and colostrum should improve infant care and nutrition, and lead to alternatives for individuals with milk allergies...
  48. ncbi Proteomic analysis of breast tissue and nipple aspirate fluid for breast cancer detection
    Rachel L Ruhlen
    University of Missouri Columbia, Department of Surgery, One Hospital Drive, Room N510, Columbia, MO 65212, USA
    Biomark Med 1:251-60. 2007
    ..Proteomic analysis of breast biopsies will allow more detailed characterization of the individual's cancer, with therapy tailored to the disease based on this information...
  49. pmc Pro-inflammatory responses in human monocytes are beta1-adrenergic receptor subtype dependent
    Laurel A Grisanti
    Department of Pharmacology, Physiology and Therapeutics, The University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58202 9037, USA
    Mol Immunol 47:1244-54. 2010
    ..These results demonstrate a unique synergistic pro-inflammatory response mediated through a beta(1)-AR cAMP-dependent mechanism in LPS-challenged monocytic cells...
  50. ncbi Primary angiosarcoma of the breast: do enlarged axillary nodes matter?
    Julian E Losanoff
    Department of Surgery, University of Chicago, Chicago, Illinois 60637, USA
    Breast J 12:371-4. 2006
    ..Pathology found no tumor in the lymph nodes. Based on this experience and data from the literature, we suggest evaluation of the sentinel nodes prior to potentially morbid standard level 1 and 2 axillary lymph node clearance...
  51. pmc Circulating testosterone and prostate-specific antigen in nipple aspirate fluid and tissue are associated with breast cancer
    Edward R Sauter
    Department of Surgery, Thomas Jefferson University Hospital, 1025 Walnut Street, Suite 605, Philadelphia, PA 19107, USA
    Environ Health Perspect 110:241-6. 2002
    ..NAF and serum PSA levels in postmenopausal women are correlated, suggesting that as laboratory assessment of PSA becomes more sensitive, serum PSA may become useful in identifying women with breast cancer...
  52. ncbi Prostate-specific antigen and insulin-like growth factor binding protein-3 in nipple aspirate fluid are associated with breast cancer
    Edward R Sauter
    Department of Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Cancer Detect Prev 26:149-57. 2002
    ..001). When considered jointly, only NAF PSA was significant. Therefore, NAF PSA, and to a lesser extent NAF IGFBP-3 and serum PSA, seem to be important predictors of breast cancer...
  53. pmc Proteomic analysis of nipple aspirate fluid to detect biologic markers of breast cancer
    Edward R Sauter
    Department of Surgery, Thomas Jefferson University, 1025 Walnut St, Ste 605, Philadelphia, PA 19107, USA
    Br J Cancer 86:1440-3. 2002
    ..These findings suggest that (1) differential expression of nipple aspirate fluid proteins exists between women with normal and diseased breasts, and (2) analysis of these proteins may predict the presence of breast cancer...