Satriano J, Ishizuka S, Archer D, Blantz R, Kelly C. Regulation of intracellular polyamine biosynthesis and transport by NO and cytokines TNF-alpha and IFN-gamma. Am J Physiol. 1999;276:C892-9 pubmed
..This study demonstrates the capacity of NO and inflammatory cytokines to regulate both polyamine biosynthesis and transport. ..
Satriano J. Kidney growth, hypertrophy and the unifying mechanism of diabetic complications. Amino Acids. 2007;33:331-9 pubmed
..Here we will evaluate this growth phenomenon in the context of diabetes mellitus. ..
Satriano J, Mansoury H, Deng A, Sharma K, Vallon V, Blantz R, et al. Transition of kidney tubule cells to a senescent phenotype in early experimental diabetes. Am J Physiol Cell Physiol. 2010;299:C374-80 pubmed publisher
..These data delineate a phenotypic change in cortical tubules early in the pathogenesis of diabetes that may contribute to further downstream complications of the disease. ..
Satriano J, Sharma K, Blantz R, Deng A. Induction of AMPK activity corrects early pathophysiological alterations in the subtotal nephrectomy model of chronic kidney disease. Am J Physiol Renal Physiol. 2013;305:F727-33 pubmed publisher
..We propose that induction of AMPK activity may prove an effective therapeutic target for the treatment of nondiabetic CKD. ..
Satriano J, Isome M, Casero R, Thomson S, Blantz R. Polyamine transport system mediates agmatine transport in mammalian cells. Am J Physiol Cell Physiol. 2001;281:C329-34 pubmed
..The fact that this transport system is associated with proliferation could be of consequence to the antiproliferative effects of agmatine...