ANDREA JANINE SANT
Affiliation: University of Rochester
DiPiazza A, Richards K, Liu W, Albrecht R, Sant A. Analyses of Cellular Immune Responses in Ferrets Following Influenza Virus Infection. Methods Mol Biol. 2018;1836:513-530 pubmed publisher
..The detailed procedures for these techniques are described in this chapter and can likely be adapted for the analyses of responses to many respiratory pathogens. ..
Sant A, McMichael A. Revealing the role of CD4(+) T cells in viral immunity. J Exp Med. 2012;209:1391-5 pubmed publisher
..We highlight several recent reports, including one published in this issue, that have employed comprehensive and sophisticated approaches to provide new evidence for CD4(+) T cells as direct effectors in antiviral immunity. ..
Sant A, Richards K, Nayak J. Distinct and complementary roles of CD4 T cells in protective immunity to influenza virus. Curr Opin Immunol. 2018;53:13-21 pubmed publisher
Dipiazza A, Laniewski N, Rattan A, Topham D, Miller J, Sant A. CD4 T Cell Epitope Specificity and Cytokine Potential Are Preserved as Cells Transition from the Lung Vasculature to Lung Tissue following Influenza Virus Infection. J Virol. 2018;92: pubmed publisher
Dipiazza A, Richards K, Poulton N, Sant A. Avian and Human Seasonal Influenza Hemagglutinin Proteins Elicit CD4 T Cell Responses That Are Comparable in Epitope Abundance and Diversity. Clin Vaccine Immunol. 2017;24: pubmed publisher
Dipiazza A, Richards K, Batarse F, Lockard L, Zeng H, Garcia Sastre A, et al
. Flow Cytometric and Cytokine ELISpot Approaches To Characterize the Cell-Mediated Immune Response in Ferrets following Influenza Virus Infection. J Virol. 2016;90:7991-8004 pubmed publisher
Dipiazza A, Nogales A, Poulton N, Wilson P, MartÃnez Sobrido L, Sant A. Pandemic 2009 H1N1 Influenza Venus reporter virus reveals broad diversity of MHC class II-positive antigen-bearing cells following infection in vivo. Sci Rep. 2017;7:10857 pubmed publisher
..Collectively, these studies have revealed the cellular heterogeneity and complexity of antigen-bearing cells within the lung and their potential as targets of antigen recognition by CD4 T cells. ..