Sumathi Sankaran-Walters

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Sex differences matter in the gut: effect on mucosal immune activation and inflammation
    Sumathi Sankaran-Walters
    Department of Medical Microbiology and Immunology, University of CA Davis Health System, 5605A GBSF, 451 Health Sciences Drive, Davis, CA 95616, USA
    Biol Sex Differ 4:10. 2013
  2. pmc Epstein-Barr virus replication linked to B cell proliferation in inflamed areas of colonic mucosa of patients with inflammatory bowel disease
    Sumathi Sankaran-Walters
    Department of Medical Microbiology and Immunology, University of California, Davis, CA 95616, United States
    J Clin Virol 50:31-6. 2011
  3. pmc Intestinal epithelial barrier disruption through altered mucosal microRNA expression in human immunodeficiency virus and simian immunodeficiency virus infections
    Christopher A Gaulke
    Department of Medical Microbiology and Immunology, University of California, Davis, California, USA
    J Virol 88:6268-80. 2014
  4. pmc Enhanced innate antiviral gene expression, IFN-α, and cytolytic responses are predictive of mucosal immune recovery during simian immunodeficiency virus infection
    David Verhoeven
    Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA 95616
    J Immunol 192:3308-18. 2014
  5. pmc Dysregulation of anti-inflammatory annexin A1 expression in progressive Crohns Disease
    Angela Sena
    Department of Medical Microbiology and Immunology, University of California Davis, Davis, California, United States of America Nanobiotechnology Laboratory, Institute of Genetics and Biochemistry, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil
    PLoS ONE 8:e76969. 2013
  6. pmc Transcription profiling reveals potential mechanisms of dysbiosis in the oral microbiome of rhesus macaques with chronic untreated SIV infection
    Susan Ocon
    Department of Medical Microbiology and Immunology, University of California Davis, Davis, California, United States of America
    PLoS ONE 8:e80863. 2013
  7. pmc Early mucosal sensing of SIV infection by paneth cells induces IL-1β production and initiates gut epithelial disruption
    Lauren A Hirao
    Department of Medical Microbiology and Immunology, University of California, Davis, Davis, California, United States of America
    PLoS Pathog 10:e1004311. 2014
  8. pmc Transcriptional profiling of peripheral CD8+T cell responses to SIVΔnef and SIVmac251 challenge reveals a link between protective immunity and induction of systemic immunoregulatory mechanisms
    Michael D George
    Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA, United States
    Virology 468:581-91. 2014
  9. pmc Chronic HIV infection enhances the responsiveness of antigen presenting cells to commensal Lactobacillus
    Lauren H Nagy
    Department of Medical Microbiology and Immunology, University of California Davis, Davis, California, United States of America
    PLoS ONE 8:e72789. 2013
  10. pmc Evidence of an increased pathogenic footprint in the lingual microbiome of untreated HIV infected patients
    Angeline T Dang
    Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA, USA
    BMC Microbiol 12:153. 2012

Collaborators

  • Angeline T Dang
  • Maria L Marco
  • ANDREAS J BAUMLER
  • George R Thompson
  • R Paul Johnson
  • Olivier Bourry
  • Ian Korf
  • Anne Thai
  • Renee M Tsolis
  • Andre J Ouellette
  • Michael Syvanen
  • Renato L Santos
  • Satya Dandekar
  • Michael D George
  • Irina Grishina
  • Guochun Jiang
  • Christopher A Gaulke
  • Lauren A Hirao
  • Monica Macal
  • William Hu
  • David Verhoeven
  • Ross Tarara
  • William K Hu
  • Anne Fenton
  • Lauren H Nagy
  • Susan Ocon
  • Angela Sena
  • Joseph K Wong
  • Thomas Prindiville
  • Melinda M Zaragoza
  • Paula Lerner
  • Tatiane A Paixao
  • Zeljka Smit-McBride
  • Philipp Kaiser
  • Frank Chuang
  • Matthew Porter
  • Yan Hong Han
  • Robert W Crawford
  • Yuyang Tang
  • James M Billingsley
  • Greg P Melcher
  • Mariana G Weber
  • Anne N Fenton
  • Jay A Li
  • R Keith Reeves
  • Luiz F Pianowski
  • Erica A Mendes
  • Monsicha Somrit
  • Chris A Gaulke
  • Amilcar Tanuri
  • Elizabeth Reay
  • Holland Cheng
  • Shou Wei Ding
  • Niku Borujerdpur
  • Christina Murphy
  • Luiz Goulart
  • Jennifer Brown
  • Larissa Goulart
  • Sonia Maria Oliani
  • Smita Ghanekar
  • Bruce J Paster
  • Jay Li
  • Maria Suni
  • Chin Shang Li
  • Richard Pollard
  • Enrique Martinez
  • Don R Canfield
  • Jason K S Hung
  • Jason Flamm
  • Moraima Guadalupe
  • Jason Hung
  • Richard Donovan
  • Christelle M Roux
  • Andreas B den Hartigh

Detail Information

Publications14

  1. pmc Sex differences matter in the gut: effect on mucosal immune activation and inflammation
    Sumathi Sankaran-Walters
    Department of Medical Microbiology and Immunology, University of CA Davis Health System, 5605A GBSF, 451 Health Sciences Drive, Davis, CA 95616, USA
    Biol Sex Differ 4:10. 2013
    ..It is thus hypothesized that a baseline sex-associated difference in immune activation may predispose women to inflammation-associated disease...
  2. pmc Epstein-Barr virus replication linked to B cell proliferation in inflamed areas of colonic mucosa of patients with inflammatory bowel disease
    Sumathi Sankaran-Walters
    Department of Medical Microbiology and Immunology, University of California, Davis, CA 95616, United States
    J Clin Virol 50:31-6. 2011
    ..Anti-viral strategies may be a viable treatment option if severity of EBV infection, reflected in peripheral blood, contributes to IBD progression...
  3. pmc Intestinal epithelial barrier disruption through altered mucosal microRNA expression in human immunodeficiency virus and simian immunodeficiency virus infections
    Christopher A Gaulke
    Department of Medical Microbiology and Immunology, University of California, Davis, California, USA
    J Virol 88:6268-80. 2014
    ....
  4. pmc Enhanced innate antiviral gene expression, IFN-α, and cytolytic responses are predictive of mucosal immune recovery during simian immunodeficiency virus infection
    David Verhoeven
    Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA 95616
    J Immunol 192:3308-18. 2014
    ..Thus, unique immune mechanisms contribute to the differential response and protection of pulmonary versus GI mucosa and can be leveraged to enhance mucosal recovery. ..
  5. pmc Dysregulation of anti-inflammatory annexin A1 expression in progressive Crohns Disease
    Angela Sena
    Department of Medical Microbiology and Immunology, University of California Davis, Davis, California, United States of America Nanobiotechnology Laboratory, Institute of Genetics and Biochemistry, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil
    PLoS ONE 8:e76969. 2013
    ..The goal of this study was to examine the association between ANXA1 and IBD, and the effects of anti-TNF-α, Infliximab (IFX), therapy on ANXA1 expression...
  6. pmc Transcription profiling reveals potential mechanisms of dysbiosis in the oral microbiome of rhesus macaques with chronic untreated SIV infection
    Susan Ocon
    Department of Medical Microbiology and Immunology, University of California Davis, Davis, California, United States of America
    PLoS ONE 8:e80863. 2013
    ..Finally, we provide evidence that the increased capacity of opportunistic pathogens (e.g. E. coli) to colonize the microbiome is associated with reduced production of antimicrobial peptides. ..
  7. pmc Early mucosal sensing of SIV infection by paneth cells induces IL-1β production and initiates gut epithelial disruption
    Lauren A Hirao
    Department of Medical Microbiology and Immunology, University of California, Davis, Davis, California, United States of America
    PLoS Pathog 10:e1004311. 2014
    ....
  8. pmc Transcriptional profiling of peripheral CD8+T cell responses to SIVΔnef and SIVmac251 challenge reveals a link between protective immunity and induction of systemic immunoregulatory mechanisms
    Michael D George
    Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA, United States
    Virology 468:581-91. 2014
    ..The study highlights potential immunomodulatory networks associated with protective immunity against the virus. ..
  9. pmc Chronic HIV infection enhances the responsiveness of antigen presenting cells to commensal Lactobacillus
    Lauren H Nagy
    Department of Medical Microbiology and Immunology, University of California Davis, Davis, California, United States of America
    PLoS ONE 8:e72789. 2013
    ..Our findings suggest that chronic HIV infection enhances the responsiveness of APCs to commensal lactobacilli, a mechanism that may partly contribute to chronic immune activation. ..
  10. pmc Evidence of an increased pathogenic footprint in the lingual microbiome of untreated HIV infected patients
    Angeline T Dang
    Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA, USA
    BMC Microbiol 12:153. 2012
    ..The relationship between clinical parameters (viral burden and CD4+ T cell depletion) and the loss or gain of bacterial species was evaluated in each HIV patient group...
  11. pmc The gut mucosal viral reservoir in HIV-infected patients is not the major source of rebound plasma viremia following interruption of highly active antiretroviral therapy
    Paula Lerner
    Dept of Medical Microbiology and Immunology, GBSF, Room 5511, University of California, Davis, California 95616, USA
    J Virol 85:4772-82. 2011
    ..Early detection of and therapy for HIV infection may be beneficial in controlling viral evolution and limiting establishment of diverse viral reservoirs in the mucosal compartment...
  12. pmc Persistence of gut mucosal innate immune defenses by enteric α-defensin expression in the simian immunodeficiency virus model of AIDS
    Melinda M Zaragoza
    Department of Medical Microbiology and Immunology, University of California, Davis, Davis, CA 95616, USA
    J Immunol 186:1589-97. 2011
    ..Our findings suggest that local innate immune defense exerted by PC-derived defensins contributes to the protection of gut mucosa from opportunistic infections during the course of SIV infection...
  13. doi request reprint Reactivation of HIV latency by a newly modified Ingenol derivative via protein kinase Cδ-NF-κB signaling
    Guochun Jiang
    aDepartment of Medical Microbiology and Immunology, University of California, Davis bSection of Infectious Diseases, Department of Medicine, University of California, San Francisco cDepartment of Molecular and Cellular Biology dDepartment of Internal Medicine, Division of Infectious Diseases, University of California, Davis, California, USA eInstitute of Biology and Department of Genetics, UFRJ Rio de Janeiro fKyoLab, Valinhos, Sao Paulo, Brazil Guochun Jiang and Erica A Mendes contributed equally to the writing of this article
    AIDS 28:1555-66. 2014
    ..The 'shock and kill' strategy involves the activation of HIV from latent reservoirs and targeting them for eradication. Our goal was to develop new approaches for activating HIV from latent reservoirs...
  14. pmc Establishment of systemic Brucella melitensis infection through the digestive tract requires urease, the type IV secretion system, and lipopolysaccharide O antigen
    Tatiane A Paixao
    Department of Medical Microbiology and Immunology, University of California at Davis, Davis, CA 95616, USA
    Infect Immun 77:4197-208. 2009
    ..These results indicate that B. melitensis is able to spread systemically from the digestive tract after infection, most likely through M cells of the mucosa-associated lymphoid tissue...