M Sammel

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Multivariate linear mixed models for multiple outcomes
    M Sammel
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Stat Med 18:2479-92. 1999
  2. ncbi Weight gain among women in the late reproductive years
    Mary D Sammel
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 423 Guardian Drive, 605 Blockly Hall, Philadelphia, PA 19104, USA
    Fam Pract 20:401-9. 2003
  3. ncbi Factors that influence entry into stages of the menopausal transition
    Mary D Sammel
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
    Menopause 16:1218-27. 2009
  4. ncbi Investigating the associations between nocturia and sleep disorders in perimenopausal women
    Manish Gopal
    Division of Urogynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Urol 180:2063-7. 2008
  5. ncbi Prediction of outcome in women with symptomatic first-trimester pregnancy: focus on intrauterine rather than ectopic gestation
    Bruno C Casanova
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Womens Health (Larchmt) 18:195-200. 2009
  6. ncbi Effect of physical activity on menopausal symptoms among urban women
    Deborah B Nelson
    Department of Public Health, College of Health Professions, Temple University, Philadelphia, PA 19122, USA
    Med Sci Sports Exerc 40:50-8. 2008
  7. ncbi Adverse neonatal outcomes: examining the risks between preterm, late preterm, and term infants
    Jamie A Bastek
    Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Am J Obstet Gynecol 199:367.e1-8. 2008
  8. ncbi Risk factors for spontaneous abortion in early symptomatic first-trimester pregnancies
    Clarisa R Gracia
    Department of Obstetrics and Gynecology, Penn Fertility Care, University of Pennsylvania Medical Center, 3701 Market Street, Philadelphia, PA 19104, USA
    Obstet Gynecol 106:993-9. 2005
  9. ncbi A functional SNP in the promoter of the SERPINH1 gene increases risk of preterm premature rupture of membranes in African Americans
    Hongyan Wang
    Center for Research on Reproduction and Women s Health and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 103:13463-7. 2006
  10. ncbi Periodontal disease and adverse pregnancy outcomes: is there an association?
    Sindhu K Srinivas
    Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, PA, USA
    Am J Obstet Gynecol 200:497.e1-8. 2009

Detail Information

Publications83

  1. ncbi Multivariate linear mixed models for multiple outcomes
    M Sammel
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Stat Med 18:2479-92. 1999
    ..The model is applied to birth defects data, where continuous data on the size of infants who were exposed to anticonvulsant medications in utero are compared to controls...
  2. ncbi Weight gain among women in the late reproductive years
    Mary D Sammel
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 423 Guardian Drive, 605 Blockly Hall, Philadelphia, PA 19104, USA
    Fam Pract 20:401-9. 2003
    ..Given the impact of obesity on mortality and morbidity in women, we evaluated correlates of weight gain in women ages 35-47 years...
  3. ncbi Factors that influence entry into stages of the menopausal transition
    Mary D Sammel
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
    Menopause 16:1218-27. 2009
    ..The aim of this study was to estimate the probabilities and identify risk factors for entering the menopausal transition and moving into each subsequent transition stage...
  4. ncbi Investigating the associations between nocturia and sleep disorders in perimenopausal women
    Manish Gopal
    Division of Urogynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Urol 180:2063-7. 2008
    ..We determined the associations between nocturia and sleep disorders in perimenopausal women...
  5. ncbi Prediction of outcome in women with symptomatic first-trimester pregnancy: focus on intrauterine rather than ectopic gestation
    Bruno C Casanova
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Womens Health (Larchmt) 18:195-200. 2009
    ..It is important to determine if efforts should focus on differentiating EP from an IUP (IUP + SAB) or a viable IUP from a nonviable gestation (EP + SAB) in women at risk for EP...
  6. ncbi Effect of physical activity on menopausal symptoms among urban women
    Deborah B Nelson
    Department of Public Health, College of Health Professions, Temple University, Philadelphia, PA 19122, USA
    Med Sci Sports Exerc 40:50-8. 2008
    ..To determine whether physical activity, measured by expended kilocalories per week (kcal.wk), decreases the risk of menopausal symptoms among African American and Caucasian women...
  7. ncbi Adverse neonatal outcomes: examining the risks between preterm, late preterm, and term infants
    Jamie A Bastek
    Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Am J Obstet Gynecol 199:367.e1-8. 2008
    ..This study sought to assess differences in adverse outcomes between infants delivering 32 to 33 6/7, 34 to 36 6/7 weeks, and 37 weeks or later...
  8. ncbi Risk factors for spontaneous abortion in early symptomatic first-trimester pregnancies
    Clarisa R Gracia
    Department of Obstetrics and Gynecology, Penn Fertility Care, University of Pennsylvania Medical Center, 3701 Market Street, Philadelphia, PA 19104, USA
    Obstet Gynecol 106:993-9. 2005
    ..Heavy bleeding was most strongly associated with miscarriage. Concurrent cervical infections should not be overlooked as a cause of bleeding in early pregnancy and were not associated with miscarriage. LEVEL OF EVIDENCE: II-2...
  9. ncbi A functional SNP in the promoter of the SERPINH1 gene increases risk of preterm premature rupture of membranes in African Americans
    Hongyan Wang
    Center for Research on Reproduction and Women s Health and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 103:13463-7. 2006
    ..0000045) association between the -656 T allele and PPROM. The SERPINH1 -656 T allele is the first example of an ancestry-informative marker associated with preterm birth in African Americans...
  10. ncbi Periodontal disease and adverse pregnancy outcomes: is there an association?
    Sindhu K Srinivas
    Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, PA, USA
    Am J Obstet Gynecol 200:497.e1-8. 2009
    ..We assessed the risk of adverse pregnancy outcomes (preterm birth [PTB], preeclampsia [PRE], fetal growth restriction [FGR], or perinatal death) in women with periodontal disease (PD) compared to those without...
  11. ncbi Detailed examination of fenfluramine-phentermine users with valve abnormalities identified in Fargo, North Dakota
    S E Kimmel
    Department of Medicine, Hospital of the University of Pennsylvania, and Center for Clinical Epidemiology, and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Am J Cardiol 84:304-8. 1999
    ..Further study is needed to test these hypotheses...
  12. ncbi A serum proteomics approach to the diagnosis of ectopic pregnancy
    G L Gerton
    Center for Research on Reproduction and Women s Health, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104 6080, USA
    Ann N Y Acad Sci 1022:306-16. 2004
    ....
  13. ncbi Predictors of sleep quality in women in the menopausal transition
    Grace W Pien
    Division of Sleep Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Sleep 31:991-9. 2008
    ..To determine associations between menopausal status, reproductive hormone levels, menopausal symptoms, and poor sleep quality...
  14. ncbi The effect of OPC Factor on energy levels in healthy adults ages 45-65: a phase IIb randomized controlled trial
    Patrick J Lariccia
    Penn Presbyterian Medical Center, Philadelphia, PA, USA
    J Altern Complement Med 14:723-32. 2008
    ..To determine the efficacy of the food supplement OPC Factor to increase energy levels in healthy adults aged 45 to 65...
  15. ncbi Body size affects measures of ovarian reserve in late reproductive age women
    H Irene Su
    Department of Obstetrics, Division of Reproductive Endocrinology and Infertility, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Menopause 15:857-61. 2008
    ..To examine the association between obesity and serum and ultrasound measures of ovarian reserve in late reproductive age women...
  16. ncbi Is routine infectious and toxicologic screening in preterm labor effective in predicting preterm birth?
    Jamie A Bastek
    Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA, USA
    Am J Obstet Gynecol 198:e38-42. 2008
    ..Our objective was to evaluate whether a significant association exists between cocaine use, cervical, urine, and/or Group B streptococcus (GBS) infections and preterm birth (PTB) in patients admitted with active preterm labor (PTL)...
  17. ncbi Hormones and sexuality during transition to menopause
    Clarisa R Gracia
    Department of Obstetrics Gynecology, Center for Clinical Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 109:831-40. 2007
    ..To examine the relationship between reproductive hormonal dynamics and sexual dysfunction assessed in a cohort of women approaching menopause...
  18. ncbi The role of patient personality in the identification of depression in older primary care patients
    Laura W McCray
    Department of Family Medicine and Community Health, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Int J Geriatr Psychiatry 22:1095-100. 2007
    ..Our aim was to evaluate whether personality factors significantly contribute to the identification of depression in older primary care patients, even after controlling for depressive symptoms...
  19. ncbi Symptoms associated with menopausal transition and reproductive hormones in midlife women
    Ellen W Freeman
    Departments of Obstetrics Gynecology, Psychiatry, University of Pennsylvania, 3701 Market Street, Philadelphia, PA 19104, USA
    Obstet Gynecol 110:230-40. 2007
    ....
  20. ncbi Panel of markers can accurately predict endometriosis in a subset of patients
    Beata Seeber
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Fertil Steril 89:1073-81. 2008
    ..To evaluate whether a combination of putative markers of inflammation and CA-125 could serve as a multiple-marker screening test for endometriosis in a heterogeneous population of patients...
  21. ncbi Metabolic score as a novel approach to assessing preeclampsia risk
    Rebecca M Mazar
    Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Am J Obstet Gynecol 197:411.e1-5. 2007
    ..Because recent evidence suggests that preeclampsia is a risk factor for future CVD, we sought to determine whether metabolic syndrome was associated with preeclampsia...
  22. ncbi Association of physical activity with reproductive hormones: the Penn Ovarian Aging Study
    Kathryn H Schmitz
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, 423 Guardian Drive, 921 Blockley Hall, Philadelphia, PA 19104, USA
    Cancer Epidemiol Biomarkers Prev 16:2042-7. 2007
    ..Few studies have examined associations of physical activity on hormone levels. None have examined the potential effect of the menopausal transition on the associations between physical activity and reproductive hormone levels...
  23. ncbi Elucidating the early signal transduction pathways leading to fetal brain injury in preterm birth
    Michal A Elovitz
    Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia 19104 6142, USA
    Pediatr Res 59:50-5. 2006
    ..With increased understanding of the mechanisms by which inflammation promotes brain injury in the preterm neonate, identification of potential targets to limit adverse neonatal outcomes becomes possible...
  24. ncbi Symptoms in the menopausal transition: hormone and behavioral correlates
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Obstet Gynecol 111:127-36. 2008
    ..To estimate the association of headache, irritability, mood swings, anxiety, and concentration difficulties with menopausal stage and with reproductive hormones in the menopausal transition...
  25. ncbi Temporal associations of hot flashes and depression in the transition to menopause
    Ellen W Freeman
    Departments of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA19104 5509, USA
    Menopause 16:728-34. 2009
    ..The aim of this study was to evaluate associations between hot flashes and depressed mood in the menopausal transition and associations of these symptoms with reproductive hormone changes...
  26. ncbi Sexual function in first-time contraceptive ring and contraceptive patch users
    Clarisa R Gracia
    Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Fertil Steril 93:21-8. 2010
    ..To assess sexual function of first-time users of the contraceptive ring and contraceptive patch...
  27. ncbi Association of change in estradiol to lower urinary tract symptoms during the menopausal transition
    Manish Gopal
    Division of Urogynecology, Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 112:1045-52. 2008
    ..To estimate the relationship between changes in estradiol (E2) levels over time and lower urinary tract symptoms in premenopausal women as they transition to menopause...
  28. ncbi Clinical factors affecting the accuracy of ultrasonography in symptomatic first-trimester pregnancy
    Kurt T Barnhart
    Department of Obstetrics and Gynecology, Center for Clinical Epidemiology and Biostatistics, Philadelphia, PA 19104, USA
    Obstet Gynecol 117:299-306. 2011
    ..To evaluate factors associated with accuracy of initial ultrasonography in patients with symptomatic first-trimester pregnancy...
  29. ncbi Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, USA
    JAMA 305:267-74. 2011
    ..Concerns regarding the risks associated with estrogen and progesterone to manage menopausal symptoms have resulted in its declining use and increased interest in nonhormonal treatments with demonstrated efficacy for hot flashes...
  30. ncbi Race, socioeconomic status, and response to methotrexate treatment of ectopic pregnancy in an urban population
    Samantha F Butts
    Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Fertil Steril 94:2789-92. 2010
    ..In this retrospective cohort study, a racial disparity in methotrexate effectiveness was not found, but a significant relationship between low socioeconomic status and methotrexate failure was demonstrated...
  31. ncbi The effects of a preterm labor episode prior to 34 weeks are evident in late preterm outcomes, despite the administration of betamethasone
    Jamie A Bastek
    Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am J Obstet Gynecol 203:140.e1-7. 2010
    ..We sought to assess whether betamethasone (BETA) <34 weeks reduces adverse outcomes in late preterm infants...
  32. ncbi Effect of hormone metabolism genotypes on steroid hormone levels and menopausal symptoms in a prospective population-based cohort of women experiencing the menopausal transition
    Timothy R Rebbeck
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Menopause 17:1026-34. 2010
    ..This study evaluated whether genes involved in the metabolism of steroid hormones are associated with hormone levels or menopausal symptoms...
  33. ncbi The use of angiogenic factors in discriminating preeclampsia: are they ready for prime time?
    Sindhu K Srinivas
    Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    J Matern Fetal Neonatal Med 23:1294-300. 2010
    ....
  34. ncbi Evidence of a gene-environment interaction that predisposes to spontaneous preterm birth: a role for asymptomatic bacterial vaginosis and DNA variants in genes that control the inflammatory response
    Luis M Gomez
    Division of Maternal Fetal Medicine, Maternal and Child Research Program, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Am J Obstet Gynecol 202:386.e1-6. 2010
    ..We determined whether an environmental exposure to bacterial vaginosis (BV) modified genetic susceptibilities for spontaneous preterm delivery within genes that regulate the inflammatory response...
  35. ncbi Obesity and reproductive hormone levels in the transition to menopause
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA, USA
    Menopause 17:718-26. 2010
    ..The aim of this study was to estimate associations of obesity with reproductive hormone levels as women progress from premenopausal to postmenopausal status...
  36. ncbi Do neonatal outcomes differ depending on the cause of preterm birth? A comparison between spontaneous birth and iatrogenic delivery for preeclampsia
    Jamie A Bastek
    Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Perinatol 27:163-9. 2010
    ..Future studies should address mechanisms by which the etiology of PTB leads to specific adverse outcomes, thus allowing for more direct interventional strategies...
  37. ncbi A strict infertility diagnosis has poor agreement with the clinical diagnosis entered into the Society for Assisted Reproductive Technology registry
    Thomas A Molinaro
    Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Fertil Steril 92:2088-90. 2009
    ..Based on a recent review of the medical literature, a clinical diagnosis of infertility may not agree with strict criteria. Standardized definitions of diagnostic categories are essential for accurate patient prognosis and future research...
  38. ncbi Evaluating the association between all components of the metabolic syndrome and pre-eclampsia
    Sindhu K Srinivas
    Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    J Matern Fetal Neonatal Med 22:501-9. 2009
    ....
  39. ncbi Time to relapse after short- or long-term treatment of severe premenstrual syndrome with sertraline
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104 5509, USA
    Arch Gen Psychiatry 66:537-44. 2009
    ..The duration of treatment after achieving a satisfactory response is unknown in the treatment of premenstrual syndrome. This information is needed in view of the improvement provided by medication vs the adverse effects and costs of drugs...
  40. ncbi Association of cyclophosphamide drug-metabolizing enzyme polymorphisms and chemotherapy-related ovarian failure in breast cancer survivors
    H Irene Su
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA 19146, USA
    Fertil Steril 94:645-54. 2010
    ..To determine if genetic variation in chemotherapy metabolism are associated with risk of ovarian failure in breast cancer patients after adjuvant chemotherapy...
  41. ncbi Core symptoms that discriminate premenstrual syndrome
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Womens Health (Larchmt) 20:29-35. 2011
    ..To identify core symptoms that discriminate premenstrual syndrome (PMS) in prospective daily diary ratings and determine the association of these symptoms with functional impairment...
  42. ncbi Prediction of location of a symptomatic early gestation based solely on clinical presentation
    Kurt T Barnhart
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 112:1319-26. 2008
    ..To evaluate three strategies for diagnosis of women at risk for ectopic pregnancy based on information collected at initial presentation...
  43. ncbi An open label pilot study of transcranial magnetic stimulation for pregnant women with major depressive disorder
    Deborah R Kim
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Womens Health (Larchmt) 20:255-61. 2011
    ..We present the results of an open label pilot study examining treatment with transcranial magnetic stimulation (TMS) in pregnant women with MDD...
  44. ncbi Vaginal birth after caesarean delivery: does maternal age affect safety and success?
    Sindhu K Srinivas
    University of Pennsylvania Health System, Department of Obstetrics and Gynecology, Philadelphia, PA 19104, USA
    Paediatr Perinat Epidemiol 21:114-20. 2007
    ..While teenage patients do not appear to be at increased risk for VBAC-related complications, patients of advanced maternal age do show an increase in composite VBAC-related operative complication rates...
  45. ncbi Predicting participation in prospective studies of ovarian aging
    Deborah B Nelson
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia, USA
    Menopause 11:543-8. 2004
    ....
  46. ncbi Functionally significant SNP MMP8 promoter haplotypes and preterm premature rupture of membranes (PPROM)
    Hongyan Wang
    Center for Research on Reproduction and Women s Health, University of Pennsylvania, 421 Curie Boulevard, Philadephia, PA 19104, USA
    Hum Mol Genet 13:2659-69. 2004
    ..52, P < 0.0002). None of the minor alleles were individually associated with PPROM. These findings demonstrate the functional significance of SNP haplotypes in the MMP8 gene and associations with obstetrical outcomes...
  47. ncbi Decline of serum human chorionic gonadotropin and spontaneous complete abortion: defining the normal curve
    Kurt Barnhart
    Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 104:975-81. 2004
    ..We sought to estimate a standard curve of serum human chorionic gonadotropin (hCG) decline that characterizes spontaneous abortion...
  48. ncbi Maternal complications with vaginal birth after cesarean delivery: a multicenter study
    George A Macones
    Department of Obstetrics and Gynecology, Leonard Davis Institute for Health Economics, University of Pennsylvania, Philadelphia, PA, USA
    Am J Obstet Gynecol 193:1656-62. 2005
    ..This study was undertaken to determine incidence and risk factors for uterine rupture in women attempting vaginal birth after cesarean delivery (VBAC) in a wide range of hospital settings...
  49. ncbi Brief communication: physical abuse of boys and possible associations with poor adult outcomes
    William C Holmes
    Philadelphia Veterans Affairs Medical Center and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6021, USA
    Ann Intern Med 143:581-6. 2005
    ..Men's childhood physical abuse experiences are understudied...
  50. ncbi Men's pathways to risky sexual behavior: role of co-occurring childhood sexual abuse, posttraumatic stress disorder, and depression histories
    William C Holmes
    Philadelphia Veterans Affairs Medical Center, MSCE University of Pennsylvania School of Medicine, 733 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    J Urban Health 82:i89-99. 2005
    ....
  51. ncbi The relationship between obesity and race on inhibin B during the menopause transition
    Clarisa R Gracia
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Menopause 12:559-66. 2005
    ..The purpose of this study was to determine the relationship among inhibin B levels, body mass index (BMI), and race during the menopause transition...
  52. ncbi Occupational exposures and male infertility
    Clarisa R Gracia
    Division of Reproductive Endocrinology and Infertility, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Epidemiol 162:729-33. 2005
    ..Overall, no clear, clinically important associations between occupational exposures and male infertility could be identified in this study...
  53. ncbi Defining menopause status: creation of a new definition to identify the early changes of the menopausal transition
    Clarisa R Gracia
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Menopause 12:128-35. 2005
    ..The objective of this study was to determine which definition captures the earliest hormonal changes in the menopausal transition...
  54. ncbi Symptomatic patients with an early viable intrauterine pregnancy: HCG curves redefined
    Kurt T Barnhart
    Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 104:50-5. 2004
    ..To analyze the change in serial human chorionic gonadotropin (hCG) levels in women symptomatic with pain or bleeding who presented with nondiagnostic ultrasonography but were ultimately confirmed to have a viable intrauterine pregnancy...
  55. ncbi Predictors of decreased libido in women during the late reproductive years
    Clarisa R Gracia
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Menopause 11:144-50. 2004
    ..To identify risk factors for decreased libido among women in the late reproductive years...
  56. ncbi Association of anti-mullerian hormone levels with obesity in late reproductive-age women
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Fertil Steril 87:101-6. 2007
    ..To describe anti-mullerian hormone (AMH) levels in healthy late reproductive age women and test the hypothesis that AMH levels are lower in obese compared to non-obese women...
  57. ncbi Psychometric properties of a menopausal symptom list
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia 19104, USA
    Menopause 10:258-65. 2003
    ..To determine psychometric properties of a brief menopause symptom list and its sensitivity to menopausal status in a population-based cohort of late reproductive-age women...
  58. ncbi Use of "2-dose" regimen of methotrexate to treat ectopic pregnancy
    Kurt Barnhart
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Fertil Steril 87:250-6. 2007
    ..To evaluate the safety and acceptability of a novel dosing regimen of methotrexate to treat ectopic pregnancy...
  59. ncbi Placental inflammation and viral infection are implicated in second trimester pregnancy loss
    Sindhu K Srinivas
    Department of Obstetrics and Gynecology, University of Pennsylvania Health System, Philadelphia, PA, USA
    Am J Obstet Gynecol 195:797-802. 2006
    ....
  60. ncbi Acute and chronic presentation of ectopic pregnancy may be two clinical entities
    Kurt T Barnhart
    Center for Reproductive Medicine and Surgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Fertil Steril 80:1345-51. 2003
    ..The purpose of this study is to analyze whether these clinical presentations represent a spectrum of disease...
  61. ncbi Hormones and menopausal status as predictors of depression in women in transition to menopause
    Ellen W Freeman
    Departments of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Mudd Suite, 3701 Market Street, Philadelphia, PA 19104 5509, USA
    Arch Gen Psychiatry 61:62-70. 2004
    ..Associations between depressed mood and hormonal changes during transition to menopause are controversial. To our knowledge, there has been no prospective study of these associations in women commencing when they are premenopausal...
  62. ncbi The role of anxiety and hormonal changes in menopausal hot flashes
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Menopause 12:258-66. 2005
    ..To estimate the association of anxiety with menopausal hot flashes in the early transition to menopause...
  63. ncbi Risk factors for ectopic pregnancy in women with symptomatic first-trimester pregnancies
    Kurt T Barnhart
    Penn Fertility Care, Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, USA
    Fertil Steril 86:36-43. 2006
    ..To evaluate the association between ectopic pregnancy (EP) and clinical and historical factors among women presenting with pain and/or bleeding in early pregnancy...
  64. ncbi Associations of hormones and menopausal status with depressed mood in women with no history of depression
    Ellen W Freeman
    Department of Obstetrics Gynecology, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
    Arch Gen Psychiatry 63:375-82. 2006
    ..Whether depressed mood reported in the transition to menopause by women with no history of depression is associated with menopausal status and changes in reproductive hormones is controversial and lacks scientific information...
  65. ncbi A preliminary study of luteal phase versus symptom-onset dosing with escitalopram for premenstrual dysphoric disorder
    Ellen W Freeman
    Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, 19104, USA
    J Clin Psychiatry 66:769-73. 2005
    ..This preliminary study compared the efficacy and tolerability of escitalopram administered at symptom onset or throughout the luteal phase in premenstrual dysphoric disorder (PMDD)...
  66. ncbi Violent injuries among women in an urban area
    J A Grisso
    Department of Biostatistics and Epidemiology and the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    N Engl J Med 341:1899-905. 1999
    ....
  67. ncbi Supplementation with DHEA: effect on muscle size, strength, quality of life, and lipids
    Molina Dayal
    Penn Fertility Care, Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Womens Health (Larchmt) 14:391-400. 2005
    ....
  68. ncbi Application of redefined human chorionic gonadotropin curves for the diagnosis of women at risk for ectopic pregnancy
    Beata E Seeber
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Fertil Steril 86:454-9. 2006
    ..Use of a more conservative cutoff for minimal rise in hCG, one as slow as 35% over 2 days, to characterize a potentially viable gestation would minimize potential interruption of a desired pregnancy...
  69. ncbi Human chorionic gonadotropin profile for women with ectopic pregnancy
    Celso Silva
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Obstet Gynecol 107:605-10. 2006
    ..The hCG profile in women with ectopic pregnancy can mimic that of an intrauterine pregnancy or a completed spontaneous abortion in approximately 29% of cases. LEVEL OF EVIDENCE: II-2...
  70. ncbi Defining the rise of serum HCG in viable pregnancies achieved through use of IVF
    Karine Chung
    University of Pennsylvania, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, 3701 Market Street, Suite 800, Philadelphia, PA 19104, USA
    Hum Reprod 21:823-8. 2006
    ..We aimed to characterize the rate of HCG rise associated with viable IVF pregnancies, and to evaluate the association between HCG rise and potentially influential factors...
  71. ncbi Tubal ligation does not affect hormonal changes during the early menopausal transition
    Deborah B Nelson
    Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Contraception 71:104-10. 2005
    ..To determine if women with a bilateral tubal ligation (BTL) were more likely to experience hormonal changes indicative of the transition to menopause or an increase in menopausal symptoms compared to women without a BTL...
  72. ncbi Risk factors for ectopic pregnancy: a comparison between adults and adolescent women
    Seema Menon
    Penn Fertility Care, Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Pediatr Adolesc Gynecol 20:181-5. 2007
    ..To compare the prevalence of classical risk factors and presenting signs and symptoms between adolescents and adults with ectopic pregnancy (EP)...
  73. ncbi Urinary incontinence and psychological distress in community-dwelling older adults
    Hillary R Bogner
    Department of Family Practice and Community Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    J Am Geriatr Soc 50:489-95. 2002
    ..We hypothesized that persons with UI associated with condition-specific functional loss would be most likely to report psychological distress...
  74. ncbi Predictors of prognosis in patients with olfactory disturbance
    Brian London
    Department of Otorhinolaryngology Head and Neck Surgery, Smell and Taste Center, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Ann Neurol 63:159-66. 2008
    ....
  75. ncbi A case-control study of female-to-female nonintimate violence in an urban area
    Nancy B Hirschinger
    Department of Criminal Justice, Widener University, Chester, PA 19103 5792, USA
    Am J Public Health 93:1098-103. 2003
    ..The aims of this study were to describe the characteristics surrounding female-to-female nonpartner violence and to identify independent factors associated with risk of female-to-female intentional injuries...
  76. ncbi Is vaginal birth after cesarean (VBAC) or elective repeat cesarean safer in women with a prior vaginal delivery?
    Alison G Cahill
    Department of Obstetrics and Gynecology, Washington University, St Louis, MO, USA
    Am J Obstet Gynecol 195:1143-7. 2006
    ..This study was undertaken to determine whether vaginal birth after cesarean (VBAC) or elective repeat cesarean delivery is safer overall for a woman with a prior vaginal delivery...
  77. ncbi Neutrophils are stimulated by syncytiotrophoblast microvillous membranes to generate superoxide radicals in women with preeclampsia
    Amal S Aly
    Center for Research on Reproduction and Women's Health, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
    Am J Obstet Gynecol 190:252-8. 2004
    ..007). CONCLUSION: STBMs in maternal blood induce neutrophils to generate superoxide radicals that may cause endothelial dysfunction in women with preeclampsia...
  78. ncbi Genetic and epigenetic mechanisms combine to control MMP1 expression and its association with preterm premature rupture of membranes
    Hongyan Wang
    State Key Laboratory of Genetic Engineering, Institute of Genetics, Fudan University School of Life Science, Shanghai 200433, China
    Hum Mol Genet 17:1087-96. 2008
    ..We conclude that in addition to genetic variation, DNA methylation plays a role in controlling MMP1 expression and risk of an adverse obstetrical outcome...
  79. ncbi A 12-bp deletion in the 5'-flanking region of the SERPINH1 gene affects promoter activity and protects against preterm premature rupture of membranes in African Americans
    Hongyan Wang
    State Key Laboratory of Genetic Engineering, Institute of Genetics, Fudan University School of Life Science, Shanghai, China
    Hum Mutat 29:332. 2008
    ..These studies define a new haplotype in the SERPINH1 gene that modifies risk of an adverse obstetrical outcome...
  80. ncbi Cocaine use during pregnancy and the failure of vaginal birth after cesarean
    Bruno F Casanova
    Department of Obstetrics and Gynecology, Pennsylvania Hospital, University of Pennsylvania, 800 Spruce Street, Philadelphia, PA 19107, USA
    J Reprod Med 50:663-8. 2005
    ..To evaluate the failure rate of a trial of vaginal birth in women with singleton pregnancies and 1 prior cesarean section who reported using cocaine during the current pregnancy...
  81. ncbi Determination of engraftment potential of human cord blood stem-progenitor cells as a function of donor cell dosage and gestational age in the NOD/SCID mouse model
    Serdar H Ural
    Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, USA
    Am J Obstet Gynecol 193:990-4. 2005
    ..Results from this study may be applicable to human postnatal and in utero transplantation studies...
  82. ncbi Evaluation of the association between hereditary thrombophilias and recurrent pregnancy loss: a meta-analysis
    George Kovalevsky
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Medical Center, Philadelphia, USA
    Arch Intern Med 164:558-63. 2004
    ..Hereditary thrombophilias may be an unrecognized cause of RPL. We recommend testing for these mutations in women with RPL...
  83. ncbi Development of a clinical prediction rule for iron deficiency anemia in pregnancy
    Bruno F Casanova
    Department of Obstetrics and Gynecology, Pennsylvania Hospital, University of Pennsylvania, Philadelphia 19107, USA
    Am J Obstet Gynecol 193:460-6. 2005
    ..The purpose of this study was to elucidate if anemia in pregnancy caused by iron deficiency could be predicted by simple measures obtained on a complete blood count (CBC) using ferritin as the gold standard...