Adam B Salmon

Summary

Affiliation: University of Texas Health Science Center
Country: USA

Publications

  1. pmc Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat
    Viviana I Perez
    Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, TX 78229, USA
    Proc Natl Acad Sci U S A 106:3059-64. 2009
  2. pmc Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging?
    Adam B Salmon
    The Sam and Ann Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Free Radic Biol Med 48:642-55. 2010
  3. pmc Oxidative damage associated with obesity is prevented by overexpression of CuZn- or Mn-superoxide dismutase
    Yuhong Liu
    The Sam and Ann Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA
    Biochem Biophys Res Commun 438:78-83. 2013
  4. pmc Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration
    Youngmok C Jang
    Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA
    FASEB J 24:1376-90. 2010
  5. pmc Short-term treatment with rapamycin and dietary restriction have overlapping and distinctive effects in young mice
    Wilson C Fok
    Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, Texas, USA
    J Gerontol A Biol Sci Med Sci 68:108-16. 2013
  6. pmc The long lifespan of two bat species is correlated with resistance to protein oxidation and enhanced protein homeostasis
    Adam B Salmon
    Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 15355 Lambda Dr, San Antonio, TX 78245 3207, USA
    FASEB J 23:2317-26. 2009
  7. pmc Methionine sulfoxide reductase A affects insulin resistance by protecting insulin receptor function
    Jennalynn Styskal
    The Sam and Ann Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Free Radic Biol Med 56:123-32. 2013
  8. pmc Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models?
    Jennalynn Styskal
    The Sam and Ann Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78245 3207, USA
    Free Radic Biol Med 52:46-58. 2012
  9. pmc Overexpression of Mn superoxide dismutase does not increase life span in mice
    Youngmok C Jang
    Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, TX 78245 3207, USA
    J Gerontol A Biol Sci Med Sci 64:1114-25. 2009
  10. pmc Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span
    Adam B Salmon
    Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 15355 Lambda Dr, San Antonio, TX 78245 3207, USA
    FASEB J 23:3601-8. 2009

Collaborators

Detail Information

Publications12

  1. pmc Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat
    Viviana I Perez
    Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, TX 78229, USA
    Proc Natl Acad Sci U S A 106:3059-64. 2009
    ..These pivotal mechanistic interspecies differences may contribute to the divergent aging profiles and strongly implicate maintenance of protein stability and integrity in successful aging...
  2. pmc Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging?
    Adam B Salmon
    The Sam and Ann Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Free Radic Biol Med 48:642-55. 2010
    ..Under these conditions, enhanced antioxidant defenses exert an "antiaging" action, leading to changes in life span, age-related pathology, and physiological function as predicted by the oxidative stress theory of aging...
  3. pmc Oxidative damage associated with obesity is prevented by overexpression of CuZn- or Mn-superoxide dismutase
    Yuhong Liu
    The Sam and Ann Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA
    Biochem Biophys Res Commun 438:78-83. 2013
    ..Together, our data suggest that targeting reduced oxidative damage in general may be a more applicable therapeutic target to prevent insulin resistance than is improving mitochondrial function. ..
  4. pmc Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration
    Youngmok C Jang
    Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA
    FASEB J 24:1376-90. 2010
    ....
  5. pmc Short-term treatment with rapamycin and dietary restriction have overlapping and distinctive effects in young mice
    Wilson C Fok
    Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, Texas, USA
    J Gerontol A Biol Sci Med Sci 68:108-16. 2013
    ....
  6. pmc The long lifespan of two bat species is correlated with resistance to protein oxidation and enhanced protein homeostasis
    Adam B Salmon
    Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 15355 Lambda Dr, San Antonio, TX 78245 3207, USA
    FASEB J 23:2317-26. 2009
    ..Together, these data suggest that long lifespan in some bat species might be regulated by very efficient maintenance of protein homeostasis...
  7. pmc Methionine sulfoxide reductase A affects insulin resistance by protecting insulin receptor function
    Jennalynn Styskal
    The Sam and Ann Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Free Radic Biol Med 56:123-32. 2013
    ..In addition, these data support a novel hypothesis that obesity-induced insulin resistance is caused in part by reduced function of insulin signaling proteins arising from protein oxidation...
  8. pmc Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models?
    Jennalynn Styskal
    The Sam and Ann Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78245 3207, USA
    Free Radic Biol Med 52:46-58. 2012
    ....
  9. pmc Overexpression of Mn superoxide dismutase does not increase life span in mice
    Youngmok C Jang
    Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, TX 78245 3207, USA
    J Gerontol A Biol Sci Med Sci 64:1114-25. 2009
    ..However, this change in MnSOD expression did not alter either life span or age-related pathology...
  10. pmc Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span
    Adam B Salmon
    Sam and Ann Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, 15355 Lambda Dr, San Antonio, TX 78245 3207, USA
    FASEB J 23:3601-8. 2009
    ..Thus, our results show that MsrA regulates sensitivity to oxidative stress in mice but has no effect on aging, as determined by life span...
  11. pmc Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome
    Wilson C Fok
    Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America
    PLoS ONE 9:e83988. 2014
    ..Our findings show that rapamycin has a major effect on the transcriptome and point to several pathways that would likely impact the longevity. ..