Research Topics
| Floyd SalleeSummaryAffiliation: University of Cincinnati Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Revisiting clonidine: an innovative add-on option for attention-deficit/hyperactivity disorderA C Childress
Center for Psychiatry and Behavioral Medicine, Inc, Las Vegas, Nevada, USA
Drugs Today (Barc) 48:207-17. 2012..This review will focus on clonidine used in conjunction with stimulants to optimize treatment of ADHD...
Efficacy of guanfacine extended release in the treatment of combined and inattentive only subtypes of attention-deficit/hyperactivity disorderFloyd R Sallee
Department of Psychiatry, University of Cincinnati, Cincinnati, OH 45219, USA
J Child Adolesc Psychopharmacol 22:206-14. 2012..This post-hoc analysis further examines the effects of GXR on hyperactivity-impulsivity and inattentiveness...- Guanfacine extended-release for attention-deficit/hyperactivity disorder (ADHD)Floyd R Sallee
University of Cincinnati, Department of Psychiatry, OH 45219, USA
Expert Opin Pharmacother 11:2549-56. 2010..GXR is a 'first in class' α(2A)-adrenoceptor agonist reformulated to optimize efficacy. GXR enters a rapidly growing but crowded ADHD market as an alternative not only to psychostimulants but also to atomoxetine... 
Adderall XR: long acting stimulant for single daily dosingFloyd R Sallee
Department of Psychiatry, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
Expert Rev Neurother 4:927-34. 2004..Relevant clinical trials and the newest data from meeting reports are also discussed...- The role of alpha2-adrenergic agonists in attention-deficit/hyperactivity disorderFloyd R Sallee
Department of Psychiatry, University of Cincinnati, 260 Stetson Street, Suite 3200, Cincinnati, OH 45219, USA
Postgrad Med 122:78-87. 2010.... - Long-term safety and efficacy of guanfacine extended release in children and adolescents with attention-deficit/hyperactivity disorderFloyd R Sallee
Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio 45219, USA
J Child Adolesc Psychopharmacol 19:215-26. 2009..This 2-year open-label study was conducted to further assess the long-term safety and efficacy of GXR... - Guanfacine extended release in children and adolescents with attention-deficit/hyperactivity disorder: a placebo-controlled trialFloyd R Sallee
Department of Psychiatry, University of Cincinnati, 231 Albert Sabin Way, ML 0559, Cincinnati, OH 45267, USA
J Am Acad Child Adolesc Psychiatry 48:155-65. 2009..This study compared the efficacy of guanfacine extended release (GXR), a selective alpha(2A)-adrenoceptor agonist, with placebo in children and adolescents with attention-deficit/hyperactivity disorder (ADHD)... - Pharmacodynamics of ziprasidone in children and adolescents: impact on dopamine transmissionFloyd R Sallee
Pharmacology Research Center, Children s Hospital Medical Center, USA
J Am Acad Child Adolesc Psychiatry 42:902-7. 2003..It is also an agonist at 5-HT(1A), which has been shown in rats to increase dopamine in prefrontal cortex. The objective of this study was to probe the dopamine agonist and antagonist pharmacodynamic properties of ziprasidone in youth... - Single-dose pharmacokinetics and safety of ziprasidone in children and adolescentsFloyd R Sallee
Department of Psychiatry, College of Medicine, University of Cincinnati, OH, USA
J Am Acad Child Adolesc Psychiatry 45:720-8. 2006.... - Effects of guanfacine extended release on oppositional symptoms in children aged 6-12 years with attention-deficit hyperactivity disorder and oppositional symptoms: a randomized, double-blind, placebo-controlled trialDaniel F Connor
Department of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut 06030 1410, USA
CNS Drugs 24:755-68. 2010..Wayne, PA, USA) in the treatment of oppositional symptoms in children aged 6-12 years with a diagnosis of attention-deficit hyperactivity disorder (ADHD) and the presence of oppositional symptoms... - Dopamine transporter genotype influences the physiological response to medication in ADHDDonald L Gilbert
Division of Neurology Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Brain 129:2038-46. 2006..In conclusion, MPH and ATX have similar effects on SICI in children with ADHD. A genetic variation in DAT1, previously linked to ADHD risk and MPH behavioural responses, influences the neurophysiological effects of both MPH and ATX... - Low cerebrospinal fluid neuropeptide Y concentrations in posttraumatic stress disorderRenu Sah
Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45237, USA
Biol Psychiatry 66:705-7. 2009..Posttraumatic stress disorder (PTSD) is a stress-related anxiety disorder. We hypothesized that central nervous system NPY is dysregulated in PTSD and sought to redress the absence of central NPY data in the disorder... - Comparison of the inhibitory and excitatory effects of ADHD medications methylphenidate and atomoxetine on motor cortexDonald L Gilbert
Division of Neurology, Cincinnati Children s Hospital Medical Center, University of Cincinnati, OH 45229, USA
Neuropsychopharmacology 31:442-9. 2006..Cortical inhibition, shown previously to be abnormal in ADHD, may play a key role producing behavioral pathology... - Tolerability and pharmacokinetics of aripiprazole in children and adolescents with psychiatric disorders: an open-label, dose-escalation studyRobert L Findling
Child and Adolescent Psychiatry, University Hospitals Case Medical Center, 11100 Euclid Ave, Cleveland, OH, USA
J Clin Psychopharmacol 28:441-6. 2008..These data provided support for exploration of a 30-mg/d dose in child/adolescent schizophrenia and bipolar disorder... - Attention-deficit hyperactivity disorder diagnosis and treatment. Separating myth from substanceDrew H Barzman
Department of Psychiatry, Cincinnati Children's Hospital Medical Center, USA
J Leg Med 25:23-38. 2004 - Association of cortical disinhibition with tic, ADHD, and OCD severity in Tourette syndromeDonald L Gilbert
Division of Neurology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Mov Disord 19:416-25. 2004..53; P = 0.003) than with tic severity (r = 0.42; P = 0.02), suggesting that in TS, the association between SICI and ADHD symptoms may be more consistent or direct than the association between SICI and tics... - Relevance of neuropeptide Y (NPY) in psychiatryKatherine Eaton
Department of Psychiatry, University of Cincinnati Medical Center, Cincinnati, OH 45267, USA
Curr Top Med Chem 7:1645-59. 2007..Reports on cerebrospinal fluid (CSF) NPY in subjects with depression indicate a dysregulation of central NPY in this disorder, however, other conditions still need to be investigated... - Interaction of NPY compounds with the rat glucocorticoid-induced receptor (GIR) reveals similarity to the NPY-Y2 receptorRenu Sah
Department of Psychiatry, University of Cincinnati Medical Center, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
Peptides 28:302-9. 2007..Our data report, for the first time, an interaction of NPY ligands with rGIR expressed in vitro, and indicate similarities between GIR and the NPY-Y(2) receptor... - Clonidine for attention-deficit/hyperactivity disorder: II. ECG changes and adverse events analysisW Burleson Daviss
University of Texas Health Science Center at San Antonio, TX, USA
J Am Acad Child Adolesc Psychiatry 47:189-98. 2008..To examine the safety and tolerability of clonidine used alone or with methylphenidate in children with attention-deficit/hyperactivity disorder (ADHD)... - Clonidine for attention-deficit/hyperactivity disorder: I. Efficacy and tolerability outcomesDonna R Palumbo
University of Rochester, USA
J Am Acad Child Adolesc Psychiatry 47:180-8. 2008..To determine the efficacy and safety of clonidine, used alone or in combination with methylphenidate, in treating attention-deficit/hyperactivity disorder (ADHD)... - Tic reduction with risperidone versus pimozide in a randomized, double-blind, crossover trialDonald L Gilbert
Department of Neurology, Cincinnati Children s Hospital Medical Center, Division of Developmental and Behavioral Sciences Children s Mercy Hospital, Kansas City, KS, USA
J Am Acad Child Adolesc Psychiatry 43:206-14. 2004..To compare the tic suppression, electrocardiogram (ECG) changes, weight gain, and side effect profiles of pimozide versus risperidone in children and adolescents with tic disorders... - A pilot safety study of repetitive transcranial magnetic stimulation (rTMS) in Tourette's syndromeJeong-Ho Chae
Brain Stimulation Laboratory, Psychiatry Department, Medical University of South Carolina, Charleston, South Carolina, USA
Cogn Behav Neurol 17:109-17. 2004..Further studies using repetitive transcranial magnetic stimulation in Tourette's syndrome are warranted, using balanced parallel designs... - Transcranial magnetic stimulation-evoked cortical inhibition: a consistent marker of attention-deficit/hyperactivity disorder scores in tourette syndromeDonald L Gilbert
Division of Neurology, Cincinnati Children s Hospital Medical Center and University of Cincinnati, OH 45229 3039, USA
Biol Psychiatry 57:1597-600. 2005..We sought to validate this observation... - Pulse-loaded intravenous clomipramine in treatment-resistant obsessive-compulsive disorderLorrin M Koran
Department of Psychiatry and Behavioral Sciences, Stanford University Medical Center, Stanford, CA 94305, USA
J Clin Psychopharmacol 26:79-83. 2006..Small studies have suggested that intravenous clomipramine (CMI) may be more effective and induce faster improvement in obsessive-compulsive disorder than do orally administered serotonin reuptake inhibitors... - A community assessment, open-label study of the safety, tolerability, and effectiveness of mixed amphetamine salts extended release in school-age children with ADHDPaul J Ambrosini
Drexel University College of Medicine, Philadelphia, PA 19124, USA
Curr Med Res Opin 22:427-40. 2006..To assess the safety, tolerability, and effectiveness of mixed amphetamine salts extended release (MAS XR) in school-age children with attention-deficit/hyperactivity disorder (ADHD) treated in a community practice setting... - SET-C versus fluoxetine in the treatment of childhood social phobiaDeborah C Beidel
Department of Psychology, University of Central Florida, Orlando, FL32186, USA
J Am Acad Child Adolesc Psychiatry 46:1622-32. 2007..To determine the efficacy of fluoxetine, pill placebo, and Social Effectiveness Therapy for Children (SET-C) for children and adolescents with social phobia... - A randomized, double-blind, placebo-controlled, parallel-group study of methylphenidate transdermal system in pediatric patients with attention-deficit/hyperactivity disorderRobert L Findling
University Hospitals Case Medical Center, Cleveland, Ohio 44106, USA
J Clin Psychiatry 69:149-59. 2008..To evaluate the efficacy and safety of methylphenidate transdermal system compared with placebo, using osmotic-release oral system (OROS) methylphenidate as a reference therapy... - Pediatric drug research and mental illnessFloyd R Sallee
FDA Consum 37:40. 2003
Research Grants
- Cortical Excitability: Phenotype and Biomarker in ADHD TherapyFloyd Sallee; Fiscal Year: 2009..This proposal will further characterize both the physiologic relevance of SICI for ADHD as well as its utility to predict response to ADHD treatments such as atomoxetine. ..
- CLONIDINE IN ADHDFloyd Sallee; Fiscal Year: 2005..abstract_text> ..
- ADHD Phenotype Network: Animal Model to Clinical TrialFloyd Sallee; Fiscal Year: 2004..abstract_text> ..
- Cortical Excitability: Phenotype and Biomarker in ADHD TherapyFloyd R Sallee; Fiscal Year: 2010..This proposal will further characterize both the physiologic relevance of SICI for ADHD as well as its utility to predict response to ADHD treatments such as atomoxetine. ..