Rosângela Salerno-Goncalves

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi Ex Vivo kinetics of early and long-term multifunctional human leukocyte antigen E-specific CD8+ cells in volunteers immunized with the Ty21a typhoid vaccine
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Vaccine Immunol 17:1305-14. 2010
  2. ncbi Immunization of volunteers with Salmonella enterica serovar Typhi strain Ty21a elicits the oligoclonal expansion of CD8+ T cells with predominant Vbeta repertoires
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland School of Medicine, 685 West Baltimore Street, HSF 480, Baltimore, MD 21201, USA
    Infect Immun 73:3521-30. 2005
  3. ncbi Characterization of CD8(+) effector T cell responses in volunteers immunized with Salmonella enterica serovar Typhi strain Ty21a typhoid vaccine
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Immunol 169:2196-203. 2002
  4. ncbi Concomitant induction of CD4+ and CD8+ T cell responses in volunteers immunized with Salmonella enterica serovar typhi strain CVD 908-htrA
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Immunol 170:2734-41. 2003
  5. ncbi Identification of a human HLA-E-restricted CD8+ T cell subset in volunteers immunized with Salmonella enterica serovar Typhi strain Ty21a typhoid vaccine
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Immunol 173:5852-62. 2004
  6. ncbi Salmonella enterica serovar Typhi live vector vaccines delivered intranasally elicit regional and systemic specific CD8+ major histocompatibility class I-restricted cytotoxic T lymphocytes
    Marcela F Pasetti
    Center for Vaccine Development, Department of Pediatrics, University of Maryland School of Medicine, Baltimore 21201, USA
    Infect Immun 70:4009-18. 2002
  7. ncbi Generation of heterogeneous memory T cells by live attenuated tularemia vaccine in humans
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland, 685 West Baltimore Street, HSF 1, Room 480, Baltimore, MD 21201, USA
    Vaccine 28:195-206. 2009
  8. ncbi Cell-mediated immune responses in humans after immunization with one or two doses of oral live attenuated typhoid vaccine CVD 909
    Rezwanul Wahid
    Center for Vaccine Development, Department of Pediatrics, University of Maryland, Baltimore, MD 21201, USA
    Vaccine 25:1416-25. 2007
  9. ncbi Cell-mediated immunity and the challenges for vaccine development
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, Department of Pediatrics, University of Maryland, 685 West Baltimore Street, HSF 1, Room 480, Baltimore, MD 21201, USA
    Trends Microbiol 14:536-42. 2006
  10. ncbi Priming of Salmonella enterica serovar typhi-specific CD8(+) T cells by suicide dendritic cell cross-presentation in humans
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD, USA
    PLoS ONE 4:e5879. 2009

Collaborators

Detail Information

Publications10

  1. ncbi Ex Vivo kinetics of early and long-term multifunctional human leukocyte antigen E-specific CD8+ cells in volunteers immunized with the Ty21a typhoid vaccine
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Clin Vaccine Immunol 17:1305-14. 2010
    ..Typhi. Finally, this is the first demonstration, in either animals or humans, of the presence of long-term multifunctional HLA-E-restricted CD8(+) cells after immunization...
  2. ncbi Immunization of volunteers with Salmonella enterica serovar Typhi strain Ty21a elicits the oligoclonal expansion of CD8+ T cells with predominant Vbeta repertoires
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland School of Medicine, 685 West Baltimore Street, HSF 480, Baltimore, MD 21201, USA
    Infect Immun 73:3521-30. 2005
    ..Moreover, these serovar Typhi-specific CD8(+) T cells bearing defined Vbeta specificities are phenotypically and functionally consistent with T effector memory cells with preferential gut homing potential...
  3. ncbi Characterization of CD8(+) effector T cell responses in volunteers immunized with Salmonella enterica serovar Typhi strain Ty21a typhoid vaccine
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Immunol 169:2196-203. 2002
    ..001). In conclusion, this work constitutes the first evidence that immunization of volunteers with Ty21a elicits specific CD8(+) CTL and provides an estimate of the frequency of CD8(+) IFN-gamma-secreting cells induced by vaccination...
  4. ncbi Concomitant induction of CD4+ and CD8+ T cell responses in volunteers immunized with Salmonella enterica serovar typhi strain CVD 908-htrA
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Immunol 170:2734-41. 2003
    ....
  5. ncbi Identification of a human HLA-E-restricted CD8+ T cell subset in volunteers immunized with Salmonella enterica serovar Typhi strain Ty21a typhoid vaccine
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Immunol 173:5852-62. 2004
    ....
  6. ncbi Salmonella enterica serovar Typhi live vector vaccines delivered intranasally elicit regional and systemic specific CD8+ major histocompatibility class I-restricted cytotoxic T lymphocytes
    Marcela F Pasetti
    Center for Vaccine Development, Department of Pediatrics, University of Maryland School of Medicine, Baltimore 21201, USA
    Infect Immun 70:4009-18. 2002
    ..The results further support the usefulness of the murine intranasal model for evaluating the immunogenicity of typhoid vaccine candidates at the preclinical level...
  7. ncbi Generation of heterogeneous memory T cells by live attenuated tularemia vaccine in humans
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland, 685 West Baltimore Street, HSF 1, Room 480, Baltimore, MD 21201, USA
    Vaccine 28:195-206. 2009
    ..Thus, regardless of whether by immunization or natural exposure, tularemia antigens elicited a broad spectrum of specific T(M) subsets with diverse homing characteristics...
  8. ncbi Cell-mediated immune responses in humans after immunization with one or two doses of oral live attenuated typhoid vaccine CVD 909
    Rezwanul Wahid
    Center for Vaccine Development, Department of Pediatrics, University of Maryland, Baltimore, MD 21201, USA
    Vaccine 25:1416-25. 2007
    ..These observations add impetus for the continuing evaluation of CVD 909 as a typhoid vaccine candidate...
  9. ncbi Cell-mediated immunity and the challenges for vaccine development
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, Department of Pediatrics, University of Maryland, 685 West Baltimore Street, HSF 1, Room 480, Baltimore, MD 21201, USA
    Trends Microbiol 14:536-42. 2006
    ..Age also has an impact on vaccine design because of the physiological changes in cell-mediated immunity that occur throughout life...
  10. ncbi Priming of Salmonella enterica serovar typhi-specific CD8(+) T cells by suicide dendritic cell cross-presentation in humans
    Rosângela Salerno-Goncalves
    Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, MD, USA
    PLoS ONE 4:e5879. 2009
    ..Recent studies in mice have shown that dendritic cells (DC) can either directly (upon uptake and processing of Salmonella) or indirectly (by bystander mechanisms) elicit Salmonella-specific CD8(+) T cells...