Michele Sale

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. pmc Significant linkage at chromosome 19q for otitis media with effusion and/or recurrent otitis media (COME/ROM)
    Wei Min Chen
    Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA
    BMC Med Genet 12:124. 2011
  2. pmc Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy
    Tennille S Leak
    Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
    BMC Med Genet 11:22. 2010
  3. pmc Evaluation of 15 functional candidate genes for association with chronic otitis media with effusion and/or recurrent otitis media (COME/ROM)
    Michele M Sale
    Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America
    PLoS ONE 6:e22297. 2011
  4. pmc Genome-wide linkage scan in Gullah-speaking African American families with type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR)
    Michele M Sale
    Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA
    Diabetes 58:260-7. 2009
  5. ncbi request reprint Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy
    Michele M Sale
    Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Diabetes 56:2638-42. 2007
  6. pmc Robust relationship inference in genome-wide association studies
    Ani Manichaikul
    Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA
    Bioinformatics 26:2867-73. 2010
  7. pmc Cardiovascular risk in Gullah African Americans with high familial risk of type 2 diabetes mellitus: project SuGAR
    Kelly J Hunt
    From the Department of Public Health Sciences and the College of Nursing, Medical University of South Carolina, Charleston, and the Health Equity and Rural Outreach Innovation Center, Ralph H Johnson Department of Veterans Affairs Medical Center, Charleston, South Carolina, the Department of Nutrition Sciences, University of Alabama at Birmingham, and the Center for Public Health Genomics, University of Virginia, Charlottesville
    South Med J 107:607-14. 2014
  8. doi request reprint 16S rRNA survey revealed complex bacterial communities and evidence of bacterial interference on human adenoids
    Tiantian Ren
    Department of Biology, University of Virginia, Charlottesville, VA 22904, USA
    Environ Microbiol 15:535-47. 2013
  9. pmc Transcobalamin 2 variant associated with poststroke homocysteine modifies recurrent stroke risk
    F C Hsu
    Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Neurology 77:1543-50. 2011

Research Grants

Collaborators

Detail Information

Publications10

  1. pmc Significant linkage at chromosome 19q for otitis media with effusion and/or recurrent otitis media (COME/ROM)
    Wei Min Chen
    Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA
    BMC Med Genet 12:124. 2011
    ..We carried out a nonparametric linkage analysis, modeling marker-to-marker linkage disequilibrium...
  2. pmc Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy
    Tennille S Leak
    Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
    BMC Med Genet 11:22. 2010
    ..Ordered subset linkage analysis (OSA) revealed a linkage peak on chromosome 7p in the subset of families with earlier age of T2D diagnosis...
  3. pmc Evaluation of 15 functional candidate genes for association with chronic otitis media with effusion and/or recurrent otitis media (COME/ROM)
    Michele M Sale
    Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America
    PLoS ONE 6:e22297. 2011
    ..The candidate gene variants examined do not appear to make a major contribution to COME/ROM susceptibility, despite a priori evidence from functional or animal model studies for a role in COME/ROM pathology...
  4. pmc Genome-wide linkage scan in Gullah-speaking African American families with type 2 diabetes: the Sea Islands Genetic African American Registry (Project SuGAR)
    Michele M Sale
    Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA
    Diabetes 58:260-7. 2009
    ..Affected relative pairs with type 2 diabetes were recruited through the Sea Islands Genetic African American Registry (Project SuGAR)...
  5. ncbi request reprint Variants of the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes in an African-American population enriched for nephropathy
    Michele M Sale
    Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Diabetes 56:2638-42. 2007
    ..Our objective was to investigate the importance of TCF7L2 in a larger African-American case-control population...
  6. pmc Robust relationship inference in genome-wide association studies
    Ani Manichaikul
    Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA
    Bioinformatics 26:2867-73. 2010
    ..Existing algorithms for relationship inference have a major weakness of estimating allele frequencies at each SNP from the entire sample, under a strong assumption of homogeneous population structure. This assumption is often untenable...
  7. pmc Cardiovascular risk in Gullah African Americans with high familial risk of type 2 diabetes mellitus: project SuGAR
    Kelly J Hunt
    From the Department of Public Health Sciences and the College of Nursing, Medical University of South Carolina, Charleston, and the Health Equity and Rural Outreach Innovation Center, Ralph H Johnson Department of Veterans Affairs Medical Center, Charleston, South Carolina, the Department of Nutrition Sciences, University of Alabama at Birmingham, and the Center for Public Health Genomics, University of Virginia, Charlottesville
    South Med J 107:607-14. 2014
    ..To determine the prevalence of cardiovascular disease, levels of cardiovascular risk factors, and extent of preventive care in Gullah African Americans with a high familial risk of type 2 diabetes mellitus...
  8. doi request reprint 16S rRNA survey revealed complex bacterial communities and evidence of bacterial interference on human adenoids
    Tiantian Ren
    Department of Biology, University of Virginia, Charlottesville, VA 22904, USA
    Environ Microbiol 15:535-47. 2013
    ..Co-occurrence analyses revealed evidence consistent with the bacterial interference theory in that multiple common pathogens showed 'non-coexistence' relationships with non-pathogenic members of the commensal microflora...
  9. pmc Transcobalamin 2 variant associated with poststroke homocysteine modifies recurrent stroke risk
    F C Hsu
    Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Neurology 77:1543-50. 2011
    ..We investigated genes for enzymes and cofactors in the Hcy metabolic pathway for association with Hcy and determined whether associated single nucleotide polymorphisms (SNPs) influenced recurrent stroke risk...

Research Grants1

  1. Genetic contributors to diabetes and dyslipidemia in African Americans
    Michele M Sale; Fiscal Year: 2010
    ..We propose applying this proven strategy to identify new therapeutic targets and allow translation to novel diagnostic, prevention, and treatment strategies for type 2 diabetes. ..