Research Topics
| Mohammad M SajadiSummaryAffiliation: University of Maryland Country: USA Publications
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Detail Information
Publications
Chronic immune activation and decreased CD4 cell counts associated with hepatitis C infection in HIV-1 natural viral suppressorsMohammad M Sajadi
Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, MD 21201, USA
AIDS 26:1879-84. 2012..Further studies are needed to determine if successful HCV treatment lowers immune activation levels and/or increases CD4 cell counts in these patients...
Akhawayni and the first fever curveMohammad M Sajadi
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA
Clin Infect Dis 55:976-80. 2012..In this work we examine the history of fevers in the ancient world and the first description of the fever curve...
Correlation between circulating HIV-1 RNA and broad HIV-1 neutralizing antibody activityMohammad M Sajadi
Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, MD 21201, USA
J Acquir Immune Defic Syndr 57:9-15. 2011..To examine the relationship between HIV-1 antigenic load (plasma RNA copies/mL) and broad HIV-1 neutralizing antibody activity...
The history of facial palsy and spasm: Hippocrates to RaziMohammad M Sajadi
Department of Infectious Medicine, Division of Infectious Diseases, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA
Neurology 77:174-8. 2011..In doing so, he accurately described the clinical hallmarks of a condition that we recognize as Bell palsy...
Ibn Sina and the clinical trialMohammad M Sajadi
University of Maryland School of Medicine and Veteran Affairs Medical Center, Baltimore, Maryland, USA
Ann Intern Med 150:640-3. 2009..In addition, the authors provide a translation of his treatise on drug testing and discuss its similarity to modern concepts of pharmacology and clinical trials...
Risk factors for mortality from primary cryptococcosis in patients with HIVMohammad M Sajadi
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Postgrad Med 121:107-13. 2009..Our study findings suggest that syncope, respiratory failure, pneumonia, and admission to the intensive care unit are independently associated with an increased risk of death within 30 days after cryptococcosis diagnosis...
IL28B genotype does not correlate with HIV control in African AmericansMohammad M Sajadi
Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, Maryland, USA
Clin Transl Sci 4:282-4. 2011....
Epidemiologic characteristics and natural history of HIV-1 natural viral suppressorsMohammad M Sajadi
Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, MD, USA
J Acquir Immune Defic Syndr 50:403-8. 2009....
Hepatitis C infection in HIV-1 natural viral suppressorsMohammad M Sajadi
Institute of Human Virology at the University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
AIDS 24:1689-95. 2010..The objective of this study was to investigate whether HIV-infected NVSs also demonstrate enhanced ability to control hepatitis C virus (HCV) infection, and whether HCV infection in the NVSs affects the degree of HIV control...
Signature biochemical properties of broadly cross-reactive HIV-1 neutralizing antibodies in human plasmaMohammad M Sajadi
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA
J Virol 86:5014-25. 2012..Such biochemical properties might be exploited to reliably predict or produce broad anti-HIV immunity...
Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 bindingYongjun Guan
Division of Basic Science and Vaccine Research, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Proc Natl Acad Sci U S A 110:E69-78. 2013..Thus, Fc-mediated effector function and neutralization coselect with specificity in anti-Env antibody responses, but the nature of selection is distinct for these two antiviral activities...
Natural viral suppressors of HIV-1 have a unique capacity to maintain gammadelta T cellsDavid J Riedel
Division of Infectious Diseases, Institute of Human Virology, University of Maryland School of Medicine, 725 W Lombard Street, Baltimore, MD 21201, USA
AIDS 23:1955-64. 2009..To evaluate Vgamma2Vdelta2 T cells in a group of HIV-infected patients who suppress HIV replication without antiretroviral therapy (natural viral suppressors, NVSs)...
Discordant memory B cell and circulating anti-Env antibody responses in HIV-1 infectionYongjun Guan
Division of Basic Science, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Proc Natl Acad Sci U S A 106:3952-7. 2009..These data suggest that plasma Ab repertoires can underestimate the breadth of humoral immunity, and analyses of B(Mem) should be included in studies correlating Ab specificity with protective immunity to HIV-1...
HIV-1 natural viral suppressors: control of viral replication in the absence of therapyMohammad M Sajadi
Institute of Human Virology, University of Maryland, Baltimore, Maryland, USA
AIDS 21:517-9. 2007..This ability to control HIV-1 viral replication naturally has led us to refer to them as natural viral suppressors...
Impact of persistent HIV replication on CD4 negative Vγ2Vδ2 T cellsSarah Boudová
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
J Infect Dis 205:1448-55. 2012..By contrasting Vγ2Vδ2 T-cell numbers, phenotype, and T-cell receptor (TCR) repertoire, we investigate the dynamic tension between active immunity and progressive T-cell destruction during persistent viremia...
Soluble factors from T cells inhibiting X4 strains of HIV are a mixture of β chemokines and RNasesFiorenza Cocchi
Institute of Human Virology and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Proc Natl Acad Sci U S A 109:5411-6. 2012..The antiviral mechanisms of these HIV X4-suppressive factors differ from those of the previously described HIV R5-suppressive β chemokines...
Tenofovir and abacavir combination therapy: lessons learned from an urban clinic populationBruce L Gilliam
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
AIDS Patient Care STDS 21:240-6. 2007....
Increased expression of suppressor of cytokine signaling-1 (SOCS-1): A mechanism for dysregulated T helper-1 responses in HIV-1 diseaseAnjana Yadav
Institute of Human Virology of the University of Maryland School of Medicine, Baltimore, MD 21201, USA
Virology 385:126-33. 2009..These results suggest a link between high levels of SOCS-1, defects in innate immunity and adaptive Th1 responses that may be reflected in the loss of Th1 immune competence observed with AIDS patients...
Medical versus medical and surgical treatment for brucella endocarditisMaryam Keshtkar-Jahromi
Union Memorial Hospital, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
Ann Thorac Surg 94:2141-6. 2012..001). This association was still significant while controlling for other contributing factors. In the absence of a controlled trial, we recommend the utmost vigilance and consideration of surgical management in treating such patients...
Abdominal pain and bacterial meningitis in a previously healthy young adultDavid J Riedel
University of Maryland, Institute of Human Virology and Div. of Infectious Diseases, 725 W. Lombard St, Rm. N560, Baltimore, MD 21201, USA
Clin Infect Dis 46:1458, 1479-80. 2008
