Rovshan G Sadygov

Summary

Affiliation: University of Texas Medical Branch
Country: USA

Publications

  1. pmc Using power spectrum analysis to evaluate (18)O-water labeling data acquired from low resolution mass spectrometers
    Rovshan G Sadygov
    Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas 77555, USA
    J Proteome Res 9:4306-12. 2010
  2. pmc Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice
    Miroslav N Nenov
    Department of Neurology, Department of Pharmacology and Toxicology, Department of Biochemistry and Molecular Biology, Department of Internal Medicine, Preventive Medicine and Community Health, Mitchell Center for Neurodegenerative Diseases, Center for Addiction Research, Center for Biomedical Engineering, and Sealy Center for Molecular Medicine, Institute for Translational Science, University of Texas Medical Branch, Galveston, Texas 77555
    J Neurosci 34:1028-36. 2014
  3. pmc Detection of structural and metabolic changes in traumatically injured hippocampus by quantitative differential proteomics
    Ping Wu
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555 1060, USA
    J Neurotrauma 30:775-88. 2013
  4. pmc Improved mass defect model for theoretical tryptic peptides
    Indranil Mitra
    Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas 77555, United States
    Anal Chem 84:3026-32. 2012
  5. pmc Altered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometry
    Jonathan M Starkey
    Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America
    PLoS ONE 5:e11095. 2010
  6. pmc Use of theoretical peptide distributions in phosphoproteome analysis
    Mridul Kalita
    Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77573, USA
    J Proteome Res 12:3207-14. 2013
  7. pmc A parallel method for enumerating amino acid compositions and masses of all theoretical peptides
    Alexey V Nefedov
    Department of Biochemistry and Molecular Biology, Sealy Center for Molecular Medicine, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, USA
    BMC Bioinformatics 12:432. 2011
  8. pmc Examining troughs in the mass distribution of all theoretically possible tryptic peptides
    Alexey V Nefedov
    Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas 77555, United States
    J Proteome Res 10:4150-7. 2011
  9. pmc SVM model for quality assessment of medium resolution mass spectra from 18O-water labeling experiments
    Alexey V Nefedov
    Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas 77555, United States
    J Proteome Res 10:2095-103. 2011
  10. pmc Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways
    Larry A Denner
    Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, Galveston, Texas 77555, USA
    J Neurosci 32:16725-35a. 2012

Collaborators

Detail Information

Publications11

  1. pmc Using power spectrum analysis to evaluate (18)O-water labeling data acquired from low resolution mass spectrometers
    Rovshan G Sadygov
    Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas 77555, USA
    J Proteome Res 9:4306-12. 2010
    ..Comparison with another algorithm for ratio estimations demonstrates the increased precision and automation of MassXplorer...
  2. pmc Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice
    Miroslav N Nenov
    Department of Neurology, Department of Pharmacology and Toxicology, Department of Biochemistry and Molecular Biology, Department of Internal Medicine, Preventive Medicine and Community Health, Mitchell Center for Neurodegenerative Diseases, Center for Addiction Research, Center for Biomedical Engineering, and Sealy Center for Molecular Medicine, Institute for Translational Science, University of Texas Medical Branch, Galveston, Texas 77555
    J Neurosci 34:1028-36. 2014
    ....
  3. pmc Detection of structural and metabolic changes in traumatically injured hippocampus by quantitative differential proteomics
    Ping Wu
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555 1060, USA
    J Neurotrauma 30:775-88. 2013
    ..This large-scale knowledge base lays the foundation for the identification of novel therapeutic targets for cognitive rescue in TBI...
  4. pmc Improved mass defect model for theoretical tryptic peptides
    Indranil Mitra
    Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas 77555, United States
    Anal Chem 84:3026-32. 2012
    ..We propose that a new model for mass defects and peak widths of peptides may improve peptide identifications by filtering chemical noise in mass spectral data...
  5. pmc Altered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometry
    Jonathan M Starkey
    Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, United States of America
    PLoS ONE 5:e11095. 2010
    ..We utilized a global, quantitative, differential proteomic approach to identify a novel retinoic acid hub in renal cortical protein networks dysregulated by type 2 diabetes...
  6. pmc Use of theoretical peptide distributions in phosphoproteome analysis
    Mridul Kalita
    Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77573, USA
    J Proteome Res 12:3207-14. 2013
    ..For our studies we used publicly available data sets from three large-scale proteomic studies. ..
  7. pmc A parallel method for enumerating amino acid compositions and masses of all theoretical peptides
    Alexey V Nefedov
    Department of Biochemistry and Molecular Biology, Sealy Center for Molecular Medicine, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, USA
    BMC Bioinformatics 12:432. 2011
    ..The increasing availability of parallel (multi-core) computers in all fields of research makes the development of parallel methods for peptide enumeration a timely topic...
  8. pmc Examining troughs in the mass distribution of all theoretically possible tryptic peptides
    Alexey V Nefedov
    Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas 77555, United States
    J Proteome Res 10:4150-7. 2011
    ..The results of this work can be used to facilitate protein identification and mass defect labeling in mass spectrometry-based proteomics experiments...
  9. pmc SVM model for quality assessment of medium resolution mass spectra from 18O-water labeling experiments
    Alexey V Nefedov
    Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas 77555, United States
    J Proteome Res 10:2095-103. 2011
    ..We demonstrated that filtering the data using our SVM classifier results in as much as a 9-fold reduction in the coefficient of variance of peptide ratios, thus significantly improving the reliability of ratio estimations...
  10. pmc Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways
    Larry A Denner
    Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, Galveston, Texas 77555, USA
    J Neurosci 32:16725-35a. 2012
    ..Thus, PPARγ represents a signaling system that is not crucial for normal cognition yet can intercede to restore neural networks compromised by AD...
  11. pmc A new probabilistic database search algorithm for ETD spectra
    Rovshan G Sadygov
    Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    J Proteome Res 8:3198-205. 2009
    ..At the same time, we demonstrate that there are substantial differences with OMSSA for results on subsets of data. Therefore, we conclude the new model can be considered as being complementary to previously developed models...