Research Topics
| Jane S SaczynskiSummaryAffiliation: University of Massachusetts Medical School Country: USA Publications
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Detail Information
Publications
Cognitive trajectories after postoperative deliriumJane S Saczynski
Division of Geriatric Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA
N Engl J Med 367:30-9. 2012..Delirium is common after cardiac surgery and may be associated with long-term changes in cognitive function. We examined postoperative delirium and the cognitive trajectory during the first year after cardiac surgery...
A systematic review of validated methods for identifying heart failure using administrative dataJane S Saczynski
Division of Geriatric Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA
Pharmacoepidemiol Drug Saf 21:129-40. 2012..To identify and describe the validity of algorithms used to detect heart failure (HF) using administrative and claims data sources...- Declining length of stay for patients hospitalized with AMI: impact on mortality and readmissionsJane S Saczynski
University of Massachusetts Medical School, Worcester, MA, USA
Am J Med 123:1007-15. 2010.... - Depressive symptoms and risk of dementia: the Framingham Heart StudyJ S Saczynski
Department of Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA, USA
Neurology 75:35-41. 2010..We examined the association between depressive symptoms and incident dementia over a 17-year follow-up period... - Clinical features, treatment practices, and hospital and long-term outcomes of older patients hospitalized with decompensated heart failure: The Worcester Heart Failure StudyJane S Saczynski
Department of Medicine, Division of GeriatricMedicine, University of Massachusetts Medical School, Biotech Four, Suite 315, 377 Plantation Street, Worcester, MA 01605, USA
J Am Geriatr Soc 57:1587-94. 2009..To examine age-specific differences in clinical presentation, receipt of therapeutic practices and lifestyle recommendations, and hospital and long-term survival in patients hospitalized for acute heart failure HF... - Glycemic status and brain injury in older individuals: the age gene/environment susceptibility-Reykjavik studyJane S Saczynski
Division of Geriatric Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA
Diabetes Care 32:1608-13. 2009..To examine the association of glycemic status to magnetic resonance imaging indicators of brain pathological changes... - Cerebral infarcts and cognitive performance: importance of location and number of infarctsJane S Saczynski
Division of Geriatric Medicine, Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA
Stroke 40:677-82. 2009..Cerebral infarcts increase the risk for cognitive impairment. The relevance of location and number of infarcts with respect to cognitive function is less clear... - Trends in prehospital delay in patients with acute myocardial infarction (from the Worcester Heart Attack Study)Jane S Saczynski
University of Massachusetts Medical School, Worcester, Massachusetts, USA
Am J Cardiol 102:1589-94. 2008..In conclusion, results of this population-based study suggest that a large proportion of patients with AMI continue to show prolonged prehospital delay... - Twenty-year trends in the incidence of stroke complicating acute myocardial infarction: Worcester Heart Attack StudyJane S Saczynski
Division of Geriatric Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA
Arch Intern Med 168:2104-10. 2008..Trends in the magnitude of stroke in the setting of AMI are not well characterized, however, and neither have contemporary trends in the hospital death rates of patients developing acute stroke been examined... 
White matter lesions and cognitive performance: the role of cognitively complex leisure activityJane S Saczynski
Division of Geriatric Medicine, University of Massachusetts Medical School, Biotech Four, 377 Plantation Street, Worcester, MA 01605, USA
J Gerontol A Biol Sci Med Sci 63:848-54. 2008..Among persons with white matter lesions (WMLs), there is a range of cognitive function. We examine whether participation in leisure activities modifies the effect of WML load on cognitive function...- Cognitive impairment: an increasingly important complication of type 2 diabetes: the age, gene/environment susceptibility--Reykjavik studyJane S Saczynski
Division of Geriatric Medicine, University of Massachusetts Medical School, Biotech Four, Suite 315, 377 Plantation Street, Worcester, MA 01605, USA
Am J Epidemiol 168:1132-9. 2008..01) and poorer memory performance (beta = -0.22; P < 0.05). Persons with type 2 diabetes have poorer cognitive performance than normoglycemics, particularly in PS. Those with undiagnosed diabetes have the lowest cognitive performance... - Age and sex differences and 20-year trends (1986 to 2005) in prehospital delay in patients hospitalized with acute myocardial infarctionHoa L Nguyen
Department of Medicine, University of Massachusetts Medical School, Worcester, 01605, USA
Circ Cardiovasc Qual Outcomes 3:590-8. 2010..The objectives of this study were to examine the overall magnitude and 20-year trends (1986 to 2005) in duration of prehospital delay in middle-aged and elderly men and women hospitalized with AMI... - 30-year trends in heart failure in patients hospitalized with acute myocardial infarctionDavid D McManus
Department of Medicine, University of Massachusetts Medical School, Worcester, USA
Am J Cardiol 107:353-9. 2011..In conclusion, HF remains a common and frequently fatal complication of AMI to which increased surveillance and treatment efforts should be directed... - A systematic review of validated methods for identifying cerebrovascular accident or transient ischemic attack using administrative dataSusan E Andrade
Meyers Primary Care Institute Reliant Medical Group, Fallon Community Health Plan, and University of Massachusetts Medical School, Worcester, MA 01605, USA
Pharmacoepidemiol Drug Saf 21:100-28. 2012..To perform a systematic review of the validity of algorithms for identifying cerebrovascular accidents (CVAs) or transient ischemic attacks (TIAs) using administrative and claims data... - Trends in atrial fibrillation complicating acute myocardial infarctionJane S Saczynski
University of Massachusetts, Medical School, Worcester, MA, USA
Am J Cardiol 104:169-74. 2009..Increased surveillance and targeted therapeutic approaches appear warranted for these high-risk patients... - Weight and mortality following heart failure hospitalization among diabetic patientsMolly E Waring
Division of Epidemiology of Chronic Diseases and Vulnerable Populations, Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA
Am J Med 124:834-40. 2011..The objective of this study was to examine all-cause mortality in relation to weight status among patients with type 2 diabetes hospitalized for decompensated heart failure... - Community trends in the use and characteristics of persons with acute myocardial infarction who are transported by emergency medical servicesRobert J Goldberg
Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Heart Lung 41:323-31. 2012.... - Comparison of Medication Practices in Patients With Heart Failure and Preserved Versus Those With Reduced Ejection Fraction (from the Cardiovascular Research Network [CVRN])Robert J Goldberg
Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts Electronic address
Am J Cardiol 111:1324-9. 2013..In conclusion, the present results from a large, population-based sample suggest considerable variation in the previous and new use of different cardiac medication classes of drugs in patients with HF-PEF versus HF-REF... - Contemporary prevalence and correlates of incident heart failure with preserved ejection fractionJerry H Gurwitz
Meyers Primary Care Institute and Fallon Community Health Plan, Worcester, Mass Division of Geriatric Medicine, University of Massachusetts Medical School, Worcester Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester Electronic address
Am J Med 126:393-400. 2013.... - Patterns of Comorbidity in Older Adults with Heart Failure: The Cardiovascular Research Network PRESERVE StudyJane S Saczynski
Meyers Primary Care Institute and Fallon Community Health Plan, Worcester, Massachusetts Division of UMass Medical School Geriatric Medicine, University of Massachusetts, Worcester, Massachusetts Department of Quantitative Health Sciences, University of Massachusetts, Worcester, Massachusetts
J Am Geriatr Soc 61:26-33. 2013..To examine whether the total burden of comorbidity and pattern of co-occurring conditions varies in individuals with heart failure (HF) with preserved left ventricular ejection fraction (LVEF) (HF-P) or HF with reduced LVEF (HF-R)... - Atrial fibrillation and outcomes in heart failure with preserved versus reduced left ventricular ejection fractionDavid D McManus
Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA
J Am Heart Assoc 2:e005694. 2013..We examined how AF has impacts on adverse outcomes in HF-PEF versus HF-REF within a large, contemporary cohort... - Transitions, Risks, and Actions in Coronary Events--Center for Outcomes Research and Education (TRACE-CORE): design and rationaleMolly E Waring
Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA
Circ Cardiovasc Qual Outcomes 5:e44-50. 2012.... - Exclusion of older adults and women from recent trials of acute coronary syndromesKatherine S Dodd
Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
J Am Geriatr Soc 59:506-11. 2011..To determine whether the participation of older adults and women in published clinical trials has increased during recent years... - Age and sex differences in duration of prehospital delay in patients with acute myocardial infarction: a systematic reviewHoa L Nguyen
Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA
Circ Cardiovasc Qual Outcomes 3:82-92. 2010..This review provides an overview of the published literature that has examined age and sex differences in extent of prehospital delay in patients hospitalized with AMI... - Increase in the proportion of patients hospitalized with acute myocardial infarction with do-not-resuscitate orders already in place between 2001 and 2007: a nonconcurrent prospective studyJane S Saczynski
Department of Medicine, University of Massachusetts Medical School, Worcester Meyers Primary Care Institute, Worcester Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester
Clin Epidemiol 4:267-74. 2012..Here, we describe the use and timing of do-not-resuscitate (DNR) orders in patients hospitalized with acute myocardial infarction (AMI)... - Longitudinal study of implantable cardioverter-defibrillators: methods and clinical characteristics of patients receiving implantable cardioverter-defibrillators for primary prevention in contemporary practiceFrederick A Masoudi
Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
Circ Cardiovasc Qual Outcomes 5:e78-85. 2012..This study is being conducted to address these questions... - Recent Trends in the Incidence, Treatment, and Prognosis of Patients With Heart Failure and Atrial Fibrillation (the Worcester Heart Failure Study)David D McManus
Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts Division of Epidemiology of Chronic Disease and Vulnerable Populations, Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts Electronic address
Am J Cardiol 111:1460-5. 2013..Despite improving trends in survival, patients with ADHF and AF are at increased risk of in-hospital and postdischarge mortality... - Multiple cardiovascular comorbidities and acute myocardial infarction: temporal trends (1990-2007) and impact on death rates at 30 days and 1 yearDavid D McManus
Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
Clin Epidemiol 4:115-23. 2012.... - The relation between apolipoprotein A-I and dementia: the Honolulu-Asia aging studyJane S Saczynski
Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892, USA
Am J Epidemiol 165:985-92. 2007..These results raise the possibility that different lipoprotein components of cholesterol may be differentially associated with dementia... - Social network characteristics and cognition in middle-aged and older adultsRonald E Holtzman
Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, 624 North Broadway, Baltimore, MD 21205, USA
J Gerontol B Psychol Sci Soc Sci 59:P278-84. 2004..The findings suggest that interaction in larger social networks is a marker that portends less cognitive decline, and that distinct associational paths link interpersonal activity and emotional support to cognitive function...