Jane S Saczynski

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. pmc Patterns of comorbidity in older adults with heart failure: the Cardiovascular Research Network PRESERVE study
    Jane S Saczynski
    Meyers Primary Care Institute and Fallon Community Health Plan, Worcester, Massachusetts 01605, USA
    J Am Geriatr Soc 61:26-33. 2013
  2. pmc Cognitive trajectories after postoperative delirium
    Jane S Saczynski
    Division of Geriatric Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA
    N Engl J Med 367:30-9. 2012
  3. pmc A systematic review of validated methods for identifying heart failure using administrative data
    Jane S Saczynski
    Division of Geriatric Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Pharmacoepidemiol Drug Saf 21:129-40. 2012
  4. pmc Declining length of stay for patients hospitalized with AMI: impact on mortality and readmissions
    Jane S Saczynski
    University of Massachusetts Medical School, Worcester, MA, USA
    Am J Med 123:1007-15. 2010
  5. pmc Depressive symptoms and risk of dementia: the Framingham Heart Study
    J S Saczynski
    Department of Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA, USA
    Neurology 75:35-41. 2010
  6. pmc Clinical features, treatment practices, and hospital and long-term outcomes of older patients hospitalized with decompensated heart failure: The Worcester Heart Failure Study
    Jane S Saczynski
    Department of Medicine, Division of GeriatricMedicine, University of Massachusetts Medical School, Biotech Four, Suite 315, 377 Plantation Street, Worcester, MA 01605, USA
    J Am Geriatr Soc 57:1587-94. 2009
  7. pmc Glycemic status and brain injury in older individuals: the age gene/environment susceptibility-Reykjavik study
    Jane S Saczynski
    Division of Geriatric Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Diabetes Care 32:1608-13. 2009
  8. pmc Cerebral infarcts and cognitive performance: importance of location and number of infarcts
    Jane S Saczynski
    Division of Geriatric Medicine, Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Stroke 40:677-82. 2009
  9. pmc Trends in prehospital delay in patients with acute myocardial infarction (from the Worcester Heart Attack Study)
    Jane S Saczynski
    University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Am J Cardiol 102:1589-94. 2008
  10. pmc Twenty-year trends in the incidence of stroke complicating acute myocardial infarction: Worcester Heart Attack Study
    Jane S Saczynski
    Division of Geriatric Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Arch Intern Med 168:2104-10. 2008

Detail Information

Publications36

  1. pmc Patterns of comorbidity in older adults with heart failure: the Cardiovascular Research Network PRESERVE study
    Jane S Saczynski
    Meyers Primary Care Institute and Fallon Community Health Plan, Worcester, Massachusetts 01605, USA
    J Am Geriatr Soc 61:26-33. 2013
    ..To examine whether the total burden of comorbidity and pattern of co-occurring conditions varies in individuals with heart failure (HF) with preserved left ventricular ejection fraction (LVEF) (HF-P) or HF with reduced LVEF (HF-R)...
  2. pmc Cognitive trajectories after postoperative delirium
    Jane S Saczynski
    Division of Geriatric Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA
    N Engl J Med 367:30-9. 2012
    ..Delirium is common after cardiac surgery and may be associated with long-term changes in cognitive function. We examined postoperative delirium and the cognitive trajectory during the first year after cardiac surgery...
  3. pmc A systematic review of validated methods for identifying heart failure using administrative data
    Jane S Saczynski
    Division of Geriatric Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Pharmacoepidemiol Drug Saf 21:129-40. 2012
    ..To identify and describe the validity of algorithms used to detect heart failure (HF) using administrative and claims data sources...
  4. pmc Declining length of stay for patients hospitalized with AMI: impact on mortality and readmissions
    Jane S Saczynski
    University of Massachusetts Medical School, Worcester, MA, USA
    Am J Med 123:1007-15. 2010
    ....
  5. pmc Depressive symptoms and risk of dementia: the Framingham Heart Study
    J S Saczynski
    Department of Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA, USA
    Neurology 75:35-41. 2010
    ..We examined the association between depressive symptoms and incident dementia over a 17-year follow-up period...
  6. pmc Clinical features, treatment practices, and hospital and long-term outcomes of older patients hospitalized with decompensated heart failure: The Worcester Heart Failure Study
    Jane S Saczynski
    Department of Medicine, Division of GeriatricMedicine, University of Massachusetts Medical School, Biotech Four, Suite 315, 377 Plantation Street, Worcester, MA 01605, USA
    J Am Geriatr Soc 57:1587-94. 2009
    ..To examine age-specific differences in clinical presentation, receipt of therapeutic practices and lifestyle recommendations, and hospital and long-term survival in patients hospitalized for acute heart failure HF...
  7. pmc Glycemic status and brain injury in older individuals: the age gene/environment susceptibility-Reykjavik study
    Jane S Saczynski
    Division of Geriatric Medicine and Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Diabetes Care 32:1608-13. 2009
    ..To examine the association of glycemic status to magnetic resonance imaging indicators of brain pathological changes...
  8. pmc Cerebral infarcts and cognitive performance: importance of location and number of infarcts
    Jane S Saczynski
    Division of Geriatric Medicine, Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Stroke 40:677-82. 2009
    ..Cerebral infarcts increase the risk for cognitive impairment. The relevance of location and number of infarcts with respect to cognitive function is less clear...
  9. pmc Trends in prehospital delay in patients with acute myocardial infarction (from the Worcester Heart Attack Study)
    Jane S Saczynski
    University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Am J Cardiol 102:1589-94. 2008
    ..In conclusion, results of this population-based study suggest that a large proportion of patients with AMI continue to show prolonged prehospital delay...
  10. pmc Twenty-year trends in the incidence of stroke complicating acute myocardial infarction: Worcester Heart Attack Study
    Jane S Saczynski
    Division of Geriatric Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Arch Intern Med 168:2104-10. 2008
    ..Trends in the magnitude of stroke in the setting of AMI are not well characterized, however, and neither have contemporary trends in the hospital death rates of patients developing acute stroke been examined...
  11. pmc Cognitive impairment: an increasingly important complication of type 2 diabetes: the age, gene/environment susceptibility--Reykjavik study
    Jane S Saczynski
    Division of Geriatric Medicine, University of Massachusetts Medical School, Biotech Four, Suite 315, 377 Plantation Street, Worcester, MA 01605, USA
    Am J Epidemiol 168:1132-9. 2008
    ..01) and poorer memory performance (beta = -0.22; P < 0.05). Persons with type 2 diabetes have poorer cognitive performance than normoglycemics, particularly in PS. Those with undiagnosed diabetes have the lowest cognitive performance...
  12. ncbi request reprint White matter lesions and cognitive performance: the role of cognitively complex leisure activity
    Jane S Saczynski
    Division of Geriatric Medicine, University of Massachusetts Medical School, Biotech Four, 377 Plantation Street, Worcester, MA 01605, USA
    J Gerontol A Biol Sci Med Sci 63:848-54. 2008
    ..Among persons with white matter lesions (WMLs), there is a range of cognitive function. We examine whether participation in leisure activities modifies the effect of WML load on cognitive function...
  13. pmc Atrial fibrillation and outcomes in heart failure with preserved versus reduced left ventricular ejection fraction
    David D McManus
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical Center, Worcester, MA 01655, USA
    J Am Heart Assoc 2:e005694. 2013
    ..We examined how AF has impacts on adverse outcomes in HF-PEF versus HF-REF within a large, contemporary cohort...
  14. pmc Age and sex differences and 20-year trends (1986 to 2005) in prehospital delay in patients hospitalized with acute myocardial infarction
    Hoa L Nguyen
    Department of Medicine, University of Massachusetts Medical School, Worcester, 01605, USA
    Circ Cardiovasc Qual Outcomes 3:590-8. 2010
    ..The objectives of this study were to examine the overall magnitude and 20-year trends (1986 to 2005) in duration of prehospital delay in middle-aged and elderly men and women hospitalized with AMI...
  15. pmc 30-year trends in heart failure in patients hospitalized with acute myocardial infarction
    David D McManus
    Department of Medicine, University of Massachusetts Medical School, Worcester, USA
    Am J Cardiol 107:353-9. 2011
    ..In conclusion, HF remains a common and frequently fatal complication of AMI to which increased surveillance and treatment efforts should be directed...
  16. pmc Contemporary prevalence and correlates of incident heart failure with preserved ejection fraction
    Jerry H Gurwitz
    Meyers Primary Care Institute and Fallon Community Health Plan, Worcester, MA 01605, USA
    Am J Med 126:393-400. 2013
    ....
  17. pmc Comparison of medication practices in patients with heart failure and preserved versus those with reduced ejection fraction (from the Cardiovascular Research Network [CVRN])
    Robert J Goldberg
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA
    Am J Cardiol 111:1324-9. 2013
    ..In conclusion, the present results from a large, population-based sample suggest considerable variation in the previous and new use of different cardiac medication classes of drugs in patients with HF-PEF versus HF-REF...
  18. pmc A systematic review of validated methods for identifying cerebrovascular accident or transient ischemic attack using administrative data
    Susan E Andrade
    Meyers Primary Care Institute Reliant Medical Group, Fallon Community Health Plan, and University of Massachusetts Medical School, Worcester, MA 01605, USA
    Pharmacoepidemiol Drug Saf 21:100-28. 2012
    ..To perform a systematic review of the validity of algorithms for identifying cerebrovascular accidents (CVAs) or transient ischemic attacks (TIAs) using administrative and claims data...
  19. pmc Weight and mortality following heart failure hospitalization among diabetic patients
    Molly E Waring
    Division of Epidemiology of Chronic Diseases and Vulnerable Populations, Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Am J Med 124:834-40. 2011
    ..The objective of this study was to examine all-cause mortality in relation to weight status among patients with type 2 diabetes hospitalized for decompensated heart failure...
  20. doi request reprint Trends in atrial fibrillation complicating acute myocardial infarction
    Jane S Saczynski
    University of Massachusetts, Medical School, Worcester, MA, USA
    Am J Cardiol 104:169-74. 2009
    ..Increased surveillance and targeted therapeutic approaches appear warranted for these high-risk patients...
  21. doi request reprint Recent trends in the incidence, treatment, and prognosis of patients with heart failure and atrial fibrillation (the Worcester Heart Failure Study)
    David D McManus
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Am J Cardiol 111:1460-5. 2013
    ..Despite improving trends in survival, patients with ADHF and AF are at increased risk of in-hospital and postdischarge mortality...
  22. pmc Community trends in the use and characteristics of persons with acute myocardial infarction who are transported by emergency medical services
    Robert J Goldberg
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Heart Lung 41:323-31. 2012
    ....
  23. pmc Delayed hospital presentation in acute decompensated heart failure: clinical and patient reported factors
    Chad Darling
    Department of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Heart Lung 42:281-6. 2013
    ..Prior studies have examined the reasons why such delays may occur, but additional studies are needed to identify modifiable factors contributing to these delays...
  24. pmc Encouraging trends in acute myocardial infarction survival in the oldest old
    Jennifer Tjia
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Am J Med 126:798-804. 2013
    ..The study aim was to examine whether decade-long increases in guideline-based cardiac medication use mediate declines in post-discharge mortality among oldest old patients hospitalized with acute myocardial infarction...
  25. pmc Transitions, Risks, and Actions in Coronary Events--Center for Outcomes Research and Education (TRACE-CORE): design and rationale
    Molly E Waring
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Circ Cardiovasc Qual Outcomes 5:e44-50. 2012
    ....
  26. pmc Exclusion of older adults and women from recent trials of acute coronary syndromes
    Katherine S Dodd
    Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    J Am Geriatr Soc 59:506-11. 2011
    ..To determine whether the participation of older adults and women in published clinical trials has increased during recent years...
  27. pmc Age and sex differences in duration of prehospital delay in patients with acute myocardial infarction: a systematic review
    Hoa L Nguyen
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Circ Cardiovasc Qual Outcomes 3:82-92. 2010
    ..This review provides an overview of the published literature that has examined age and sex differences in extent of prehospital delay in patients hospitalized with AMI...
  28. doi request reprint Delirium in elderly people
    Sharon K Inouye
    Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA Electronic address
    Lancet 383:911-22. 2014
    ..Public health priorities include improvements in coding, reimbursement from insurers, and research funding, and widespread education for clinicians and the public about the importance of delirium...
  29. pmc Longitudinal study of implantable cardioverter-defibrillators: methods and clinical characteristics of patients receiving implantable cardioverter-defibrillators for primary prevention in contemporary practice
    Frederick A Masoudi
    Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
    Circ Cardiovasc Qual Outcomes 5:e78-85. 2012
    ..This study is being conducted to address these questions...
  30. pmc Increase in the proportion of patients hospitalized with acute myocardial infarction with do-not-resuscitate orders already in place between 2001 and 2007: a nonconcurrent prospective study
    Jane S Saczynski
    Department of Medicine, University of Massachusetts Medical School, Worcester Meyers Primary Care Institute, Worcester Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester
    Clin Epidemiol 4:267-74. 2012
    ..Here, we describe the use and timing of do-not-resuscitate (DNR) orders in patients hospitalized with acute myocardial infarction (AMI)...
  31. doi request reprint A tale of two methods: chart and interview methods for identifying delirium
    Jane S Saczynski
    Division of Geriatric Medicine, University of Massachusetts Medical School, Worcester, Massachusetts Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester, Massachusetts Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts
    J Am Geriatr Soc 62:518-24. 2014
    ..To compare chart- and interview-based methods for identification of delirium...
  32. pmc Commonly used data-collection approaches in clinical research
    Jane S Saczynski
    Department of Medicine, University of Massachusetts Medical School, Worcester Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester
    Am J Med 126:946-50. 2013
    ..We hope that the points raised in this overview will lead to the collection of rich and high-quality data in observational studies and randomized controlled trials. ..
  33. pmc Multiple cardiovascular comorbidities and acute myocardial infarction: temporal trends (1990-2007) and impact on death rates at 30 days and 1 year
    David D McManus
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Clin Epidemiol 4:115-23. 2012
    ....
  34. pmc Cognitive change in heart failure: a systematic review
    Alexandra M Hajduk
    Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Circ Cardiovasc Qual Outcomes 6:451-60. 2013
    ..However, the course of cognitive change in HF is not well characterized. The purpose of this systematic review was to examine the available evidence longitudinal changes in cognitive function in patients with HF...
  35. ncbi request reprint The relation between apolipoprotein A-I and dementia: the Honolulu-Asia aging study
    Jane S Saczynski
    Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892, USA
    Am J Epidemiol 165:985-92. 2007
    ..These results raise the possibility that different lipoprotein components of cholesterol may be differentially associated with dementia...
  36. ncbi request reprint Social network characteristics and cognition in middle-aged and older adults
    Ronald E Holtzman
    Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, 624 North Broadway, Baltimore, MD 21205, USA
    J Gerontol B Psychol Sci Soc Sci 59:P278-84. 2004
    ..The findings suggest that interaction in larger social networks is a marker that portends less cognitive decline, and that distinct associational paths link interpersonal activity and emotional support to cognitive function...