Michael C Sachs
Affiliation: University of Washington
- Partial summary measures of the predictiveness curveMichael C Sachs
Kidney Research Institute and Division of Nephrology, University of Washington, Seattle, WA 98104, USA
Biom J 55:589-602. 2013..We describe inferential tools for one and two samples that are shown to have adequate power in a simulation study. The methods are illustrated by assessing the accuracy of a risk score for predicting the onset of Alzheimer's disease. ..
- Circulating vitamin D metabolites and subclinical atherosclerosis in type 1 diabetesMichael C Sachs
University of Washington, Seattle, Washington, USA
Diabetes Care 36:2423-9. 2013..We tested associations of circulating vitamin D metabolite concentrations with subclinical atherosclerosis among 1,193 participants with type 1 diabetes in the DCCT/EDIC study...
- Estimating mean annual 25-hydroxyvitamin D concentrations from single measurements: the Multi-Ethnic Study of AtherosclerosisMichael C Sachs
Kidney Research Institute and Division of Nephrology, University of Washington, Seattle, WA, USA
Am J Clin Nutr 97:1243-51. 2013..Single measurements may misclassify annual exposure, which may lead to bias in research and complicate clinical decision making...
- Circulating vitamin D metabolites and kidney disease in type 1 diabetesIan H De Boer
Kidney Research Institute and Division of Nephrology, University of Washington, Box 359606, 325 Ninth Avenue, Seattle, Washington 98104, USA
J Clin Endocrinol Metab 97:4780-8. 2012..Impaired vitamin D metabolism may contribute to the development and progression of diabetic kidney disease...
- Parathyroid hormone and arterial dysfunction in the multi-ethnic study of atherosclerosisCortney Bosworth
Division of Nephrology and Kidney Research Institute, Department of Medicine, University of Washington, Seattle, WA, USA
Clin Endocrinol (Oxf) 79:429-36. 2013..Impaired arterial function is a potential mechanism for these associations. We tested whether serum PTH concentration is associated with measures of arterial function...
- Estimated GFR and Circulating 24,25-Dihydroxyvitamin D3 Concentration: A Participant-Level Analysis of 5 Cohort Studies and Clinical TrialsIan H De Boer
Division of Nephrology, Department of Medicine, Seattle, WA Kidney Research Institute, Department of Medicine, Seattle, WA Department of Epidemiology, University of Washington, Seattle, WA Electronic address
Am J Kidney Dis 64:187-97. 2014..We tested associations of estimated GFR (eGFR) with the circulating concentration of 24,25-dihydroxyvitamin D3 (24,25[OH]2D3), the most abundant product of 25(OH)D3 catabolism, across populations with a wide range of GFRs...
- Racial differences in the association of serum 25-hydroxyvitamin D concentration with coronary heart disease eventsCassianne Robinson-Cohen
Department of Medicine, Kidney Research Institute, University of Washington, Seattle 98104, USA
JAMA 310:179-88. 2013..This association has not been rigorously evaluated in other races or ethnicities, in which the distributions of 25(OH)D concentration and possibly other aspects of 25(OH)D metabolism differ...
- Kidney disease and increased mortality risk in type 2 diabetesMaryam Afkarian
Kidney Research Institute and Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA 98014, USA
J Am Soc Nephrol 24:302-8. 2013..2%-29.6%) when further adjusted. We observed similar patterns for cardiovascular and noncardiovascular mortality. In conclusion, those with kidney disease predominantly account for the increased mortality observed in type 2 diabetes...