Maria Eugenia Sabbatini

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Rap1 activation plays a regulatory role in pancreatic amylase secretion
    Maria E Sabbatini
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109 0622, USA
    J Biol Chem 283:23884-94. 2008
  2. pmc Cholecystokinin-mediated RhoGDI phosphorylation via PKCα promotes both RhoA and Rac1 signaling
    Maria Eugenia Sabbatini
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 8:e66029. 2013
  3. pmc Rgg-associated SHP signaling peptides mediate cross-talk in Streptococci
    Betty Fleuchot
    INRA, UMR1319 MICALIS, Jouy en Josas, France AgroParisTech, UMR Micalis, Jouy en Josas, France
    PLoS ONE 8:e66042. 2013
  4. pmc Adenylyl cyclase 6 mediates the action of cyclic AMP-dependent secretagogues in mouse pancreatic exocrine cells via protein kinase A pathway activation
    Maria E Sabbatini
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA
    J Physiol 591:3693-707. 2013
  5. doi request reprint Natriuretic peptides as regulatory mediators of secretory activity in the digestive system
    Maria Eugenia Sabbatini
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109 5622, United States
    Regul Pept 154:5-15. 2009
  6. pmc CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini
    Maria E Sabbatini
    Department of Molecular and Integrative Physiology, The University of Michigan, Ann Arbor, Michigan, USA
    Am J Physiol Cell Physiol 298:C592-601. 2010
  7. pmc Small G proteins as key regulators of pancreatic digestive enzyme secretion
    John A Williams
    Dept of Molecular and Integrative Physiology, Univ of Michigan, Ann Arbor, MI 48109, USA
    Am J Physiol Endocrinol Metab 296:E405-14. 2009
  8. pmc Secretin is not necessary for exocrine pancreatic development and growth in mice
    Maria Dolors Sans
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, 48109 5622, USA
    Am J Physiol Gastrointest Liver Physiol 301:G791-8. 2011

Collaborators

Detail Information

Publications8

  1. pmc Rap1 activation plays a regulatory role in pancreatic amylase secretion
    Maria E Sabbatini
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109 0622, USA
    J Biol Chem 283:23884-94. 2008
    ..Rap1 activation not only mediates the cAMP-evoked response via Epac1 but is also involved in CCK- and carbachol-induced amylase release, with their action most likely mediated by CalDAG-GEF III...
  2. pmc Cholecystokinin-mediated RhoGDI phosphorylation via PKCα promotes both RhoA and Rac1 signaling
    Maria Eugenia Sabbatini
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 8:e66029. 2013
    ..By mutational analysis we found that CCK-induced PKCα phosphorylation on RhoGDI1 at Ser96 releases RhoA and Rac1 from RhoGDI1 to facilitate Rho GTPases signaling...
  3. pmc Rgg-associated SHP signaling peptides mediate cross-talk in Streptococci
    Betty Fleuchot
    INRA, UMR1319 MICALIS, Jouy en Josas, France AgroParisTech, UMR Micalis, Jouy en Josas, France
    PLoS ONE 8:e66042. 2013
    ..Interestingly, this does not seem to be dependent on the SHP/Rgg group and cross-talk between pathogenic and non-pathogenic streptococci is observed...
  4. pmc Adenylyl cyclase 6 mediates the action of cyclic AMP-dependent secretagogues in mouse pancreatic exocrine cells via protein kinase A pathway activation
    Maria E Sabbatini
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA
    J Physiol 591:3693-707. 2013
    ..In conclusion, several AC isoforms are expressed in pancreatic acini and ducts. AC6 mediates a significant part of pancreatic amylase and fluid secretion in response to secretin, VIP and forskolin through cAMP/PKA pathway activation...
  5. doi request reprint Natriuretic peptides as regulatory mediators of secretory activity in the digestive system
    Maria Eugenia Sabbatini
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109 5622, United States
    Regul Pept 154:5-15. 2009
    ..Overall, these findings indicate that ANP and CNP are members of the large group of regulatory peptides affecting digestive secretions...
  6. pmc CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini
    Maria E Sabbatini
    Department of Molecular and Integrative Physiology, The University of Michigan, Ann Arbor, Michigan, USA
    Am J Physiol Cell Physiol 298:C592-601. 2010
    ..CCK-induced actin cytoskeletal reorganization is mainly mediated by Galpha(q). By contrast, Galpha(13) and Galpha(q) signaling are required for CCK-induced amylase secretion...
  7. pmc Small G proteins as key regulators of pancreatic digestive enzyme secretion
    John A Williams
    Dept of Molecular and Integrative Physiology, Univ of Michigan, Ann Arbor, MI 48109, USA
    Am J Physiol Endocrinol Metab 296:E405-14. 2009
    ..The Rho family small G proteins RhoA and Rac1 also regulate secretion through remodeling of the actin cytoskeleton. Possible mechanisms for regulation of these G proteins and their effector molecules are considered...
  8. pmc Secretin is not necessary for exocrine pancreatic development and growth in mice
    Maria Dolors Sans
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, 48109 5622, USA
    Am J Physiol Gastrointest Liver Physiol 301:G791-8. 2011
    ..Camostat-fed littermate secretin and secretin receptor-deficient mice had similar pancreatic mass to WT mice. These results indicate that secretin is not required for normal pancreatic development or adaptive growth mediated by CCK...