Research Topics
| Kenneth G SaagSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
Short-term and long-term safety of glucocorticoids in rheumatoid arthritisKenneth G Saag
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, 51020th Street South, Birmingham, AL 35213, USA
Bull NYU Hosp Jt Dis 70:21-5. 2012..Several new studies have contributed to an improved understanding of these associations and they are reviewed here along with highlights from the older body of literature examining these important outcomes...
Improving the efficiency and effectiveness of pragmatic clinical trials in older adults in the United StatesKenneth G Saag
Center for Education and Research on Therapeutics CERTs, Center for Outcomes Effectiveness Research and Education COERE, and Center for Clinical and Translational Sciences CCTS, University of Alabama at Birmingham, Birmingham, AL, USA
Contemp Clin Trials 33:1211-6. 2012..Testing and adaptation of such innovations to PCT are anticipated to improve the public health value of these increasingly important studies...- Effects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: thirty-six-month results of a randomized, double-blind, controlled trialKenneth G Saag
University of Alabama at Birmingham
Arthritis Rheum 60:3346-55. 2009..To compare the bone anabolic drug teriparatide (20 microg/day) with the antiresorptive drug alendronate (10 mg/day) for treating glucocorticoid-induced osteoporosis (OP)... - The effects of physician specialty and patient comorbidities on the use and discontinuation of coxibsFausto G Patino
Center for Education and Research on Therapeutics of Musculoskeletal Disorders, University of Alabama at Birmingham, 35294 3408, USA
Arthritis Rheum 49:293-9. 2003..To examine the effects of physician specialty and comorbidities on cyclooxygenase 2-selective nonsteroidal antiinflammatory drugs (NSAIDs; coxibs) utilization... 
Progress in osteoporosis and fracture prevention: focus on postmenopausal womenKenneth G Saag
Division of Clinical Immunology and Rheumatology, Center for Education and Research on Therapeutics, University of Alabama at Birmingham, 820 Faculty Office Tower, 510 20th Street South, Birmingham, AL 35294 3708, USA
Arthritis Res Ther 11:251. 2009..Emerging therapeutic options that target molecules of bone metabolism indicate that the next decade should offer even greater promise for further improving our diagnostic and treatment approaches...- Prevention of glucocorticoid-induced osteoporosisKenneth G Saag
Division of Clinical Immunology and Rheumatology, Center for Education and Research on Therapeutics of Musculoskeletal Disorders, University of Alabama at Birmingham, Birmingham, AL, USA
South Med J 97:555-8. 2004..This article discusses an evidence-based approach to the prevention of glucocorticoid-induced osteoporosis... - Glucocorticoid-induced osteoporosisKenneth G Saag
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, 1813 Sixth Avenue South, Birmingham, AL 35294 3296, USA
Endocrinol Metab Clin North Am 32:135-57, vii. 2003..This article focuses on areas of continued controversies, including the epidemiology and pathogenesis of GIOP, specification of a "safe" dose, methods for diagnosis of GIOP, and an evidence-based approach for GIOP prevention... - Recent advances in the epidemiology of goutKenneth G Saag
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 820 Faculty Office Tower, 510 20th Street South, Birmingham, AL 35294 3408, USA
Curr Rheumatol Rep 7:235-41. 2005..The importance of hyperuricemia on health considerations beyond the musculoskeletal system is an area worthy of even more study... - Glucocorticoid use in rheumatoid arthritisKenneth G Saag
Division of Clinical Immunology and Rheumatology, Center for Education and Research on Therapeutics CERTs of Musculoskeletal Disorders, University of Alabama at Birmingham, MEB 625, 1813 Sixth Avenue South, Birmingham, AL 35294 3296, USA
Curr Rheumatol Rep 4:218-25. 2002..The correct identification of patients at high risk for bone complications and the institution of appropriate preventive measures may partially attenuate this adverse outcome... - Teriparatide or alendronate in glucocorticoid-induced osteoporosisKenneth G Saag
University of Alabama at Birmingham, Birmingham 35294 3408, USA
N Engl J Med 357:2028-39. 2007..Studies of anabolic therapy in patients who are receiving long-term glucocorticoids and are at high risk for fracture are lacking... - Trends in prevention of glucocorticoid-induced osteoporosisKenneth G Saag
UAB Center for Education and Research on Musculoskeletal Disorders, University of Alabama at Birmingham, 35294, USA
J Rheumatol 33:1651-7. 2006..To determine longitudinal patterns and predictors for the utilization of bone mass measurements and anti-osteoporotic medications in the prevention of glucocorticoid-induced osteoporosis... - Epidemiology, risk factors, and lifestyle modifications for goutKenneth G Saag
UAB Center for Education and Research CERTs on Therapeutics of Musculoskeletal Disorders, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
Arthritis Res Ther 8:S2. 2006..The increasing prevalence of gout worldwide indicates that there is an urgent need for improved efforts to identify patients with hyperuricemia early in the disease process, before the clinical manifestations of gout become apparent... - Measuring quality in arthritis care: the Arthritis Foundation's quality indicator set for analgesicsKenneth G Saag
Center for Education and Research on Therapeutics of Musculoskeletal Disorders, University of Alabama at Birmingham, 35294 3296, USA
Arthritis Rheum 51:337-49. 2004..To develop systematically validated quality indicators (QIs) addressing analgesic safety... - Improving the prediction of medication compliance: the example of bisphosphonates for osteoporosisJeffrey R Curtis
Center for Education and Research on Therapeutics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Med Care 47:334-41. 2009..We tested whether adding information on compliance with other drugs used to treat chronic, asymptomatic conditions would improve the predictive ability of administrative data to identify adherent individuals... - Rates of hospitalized bacterial infection associated with juvenile idiopathic arthritis and its treatmentTimothy Beukelman
University of Alabama at Birmingham, Division of Pediatric Rheumatology, 1600 7th Avenue South, CPP 210, Birmingham, AL 35233 1711, USA
Arthritis Rheum 64:2773-80. 2012..To compare the incidence of hospitalized bacterial infections among children with and children without juvenile idiopathic arthritis (JIA) and to examine the effects of selected medications... - Agreement and validity of pharmacy data versus self-report for use of osteoporosis medications among chronic glucocorticoid usersJeffrey R Curtis
Division of Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA
Pharmacoepidemiol Drug Saf 15:710-8. 2006..Use of pharmacy data alone is unlikely to underestimate quality of osteoporosis care, but different intervals of pharmacy data have important implications on the ability to identify current users of osteoporosis medications... - Prevention and treatment of glucocorticoid-induced osteoporosisJeffrey R Curtis
University of Alabama at Birmingham, FOT 840, 510 20th Street South, Birmingham, AL 35294, USA
Curr Osteoporos Rep 5:14-21. 2007..New approaches to evidence implementation are being tested to improve the quality of osteoporosis care and decrease fracture risk among long-term glucocorticoid users... - Drug-specific and time-dependent risks of bacterial infection among patients with rheumatoid arthritis who were exposed to tumor necrosis factor alpha antagonistsJeffrey R Curtis
University of Alabama at Birmingham, AL, USA
Arthritis Rheum 56:4226-7. 2007 - Racial/ethnic disparities in patient-reported nonsteroidal antiinflammatory drug (NSAID) risk awareness, patient-doctor NSAID risk communication, and NSAID risk behaviorRachel B Fry
University of Alabama at Birmingham, Birmingham, AL, USA
Arthritis Rheum 57:1539-45. 2007..Little is known about NSAID-related ethnic/racial disparities. We focused on differences in patient NSAID risk awareness, patient-doctor NSAID risk communication, and NSAID risk-avoidance behavior... - Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritisJeffrey R Curtis
Department of Medicine, University of Alabama, 510 20th Street South, FOT 805D, Birmingham, AL 35294, USA
Arthritis Res Ther 13:R155. 2011..We created and tested a claims-based algorithm to serve as a proxy for the clinical effectiveness of RA medications... - Population-based assessment of adverse events associated with long-term glucocorticoid useJeffrey R Curtis
University of Alabama at Birmingham, 35294, USA
Arthritis Rheum 55:420-6. 2006..Physicians should be vigilant for glucocorticoid-related AEs and should counsel patients about possible risks, even among low-dose long-term users... - Use of a disease risk score to compare serious infections associated with anti-tumor necrosis factor therapy among high- versus lower-risk rheumatoid arthritis patientsJeffrey R Curtis
University of Alabama at Birmingham, Birmingham, AL, USA
Arthritis Care Res (Hoboken) 64:1480-9. 2012..To evaluate whether rates of serious infection with anti-tumor necrosis factor (anti-TNF) therapy in rheumatoid arthritis (RA) patients differ in magnitude by specific drugs and patient characteristics... - Prevalence of osteoporosis and osteopenia among African Americans with early rheumatoid arthritis: the impact of ethnic-specific normative dataTed R Mikuls
Department of Medicine, University of Nebraska Medica Center and Omaha VA Medical Center, Omaha, NE 68198 3025, USA
J Natl Med Assoc 97:1155-60. 2005..To examine the prevalence of osteopenia and/or osteoporosis among African Americans with early rheumatoid arthritis (RA) and to assess the effect of using race/ethnicity-specific normative data... - Health services utilization after fractures: evidence from MedicareDavid J Becker
Department of Health Care Organization and Policy, University of Alabama at Birmingham, 1665 University Blvd, RPHB 330H, Birmingham, AL 35294, USA
J Gerontol A Biol Sci Med Sci 65:1012-20. 2010..Postfracture utilization of health care services represents an alternative measure of the resource costs associated with these fractures... - Management of osteoporosis among home health and long-term care patients with a prior fractureAmy H Warriner
University of Alabama at Birmingham, USA
South Med J 102:397-404. 2009.... - Association between being African-American, serum urate levels and the risk of developing hyperuricemia: findings from the Coronary Artery Risk Development in Young Adults cohortAngelo L Gaffo
Birmingham VA Medical Center 700 South 19th Street, Birmingham, AL 35233, USA
Arthritis Res Ther 14:R4. 2012..We tested this hypothesis in a bi-racial cohort of younger African-American and white men and women... - Rates of malignancy associated with juvenile idiopathic arthritis and its treatmentTimothy Beukelman
University of Alabama at Birmingham, Birmingham, AL 35233 1711, USA
Arthritis Rheum 64:1263-71. 2012..To determine the relative rates of incident malignancy among children with juvenile idiopathic arthritis (JIA) with respect to treatment as compared to children without JIA... - Association between vaccination for herpes zoster and risk of herpes zoster infection among older patients with selected immune-mediated diseasesJie Zhang
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 35294, USA
JAMA 308:43-9. 2012..The safety and effectiveness of the vaccine are unclear for these patients... - Central DXA utilization shifts from office-based to hospital-based settings among medicare beneficiaries in the wake of reimbursement changesJie Zhang
Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Bone Miner Res 27:858-64. 2012..The reduction in DXA reimbursement was associated with a decrease in the number of DXAs performed in physician offices and fewer physician offices that provided DXA services... - Health and happiness among older adults: a community-based studyErik Angner
Department of Philosophy, University of Alabama at Birmingham, Birmingham, AL 35294 1260, USA
J Health Psychol 14:503-12. 2009..The results, robust to common method bias, suggest that subjective health measures are better predictors of happiness than objective measures are, except for conditions that disrupt daily functioning or are associated with social stigma... - Longitudinal patterns in the prevention of osteoporosis in glucocorticoid-treated patientsJeffrey R Curtis
University of Alabama at Birmingham, 35294, USA
Arthritis Rheum 52:2485-94. 2005.... - Identification and validation of vertebral compression fractures using administrative claims dataJeffrey R Curtis
Center for Education and Research on Therapeutics of Musculoskeletal Disorders, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Med Care 47:69-72. 2009..Vertebral compression fractures (VCFs) are the most common type of osteoporotic fracture. Administrative claims data might be useful to identify VCFs, but this approach to case finding has received limited evaluation... - Population-based fracture risk assessment and osteoporosis treatment disparities by race and genderJeffrey R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham 35294, USA
J Gen Intern Med 24:956-62. 2009..Undertreatment of osteoporosis has been recognized as a common problem in selected patient subgroups. However, primary prevention has been hampered by limited risk assessment tools that can be applied to large populations... - Nonsteroidal antiinflammatory drug toxicity monitoring and safety practicesFausto G Patino
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL 35294-3408, USA
J Rheumatol 30:2680-8. 2003..CONCLUSION: While rheumatologists and internists trended toward more CBC and creatinine testing, visit frequency, duration of NSAID use, and comorbidities were the factors most consistently associated with safety monitoring... - Challenges in improving the quality of osteoporosis care for long-term glucocorticoid users: a prospective randomized trialJeffrey R Curtis
Center for Education and Research on Therapeutics of Musculoskeletal Diseases, University of Alabama at Birmingham, AL 35294, USA
Arch Intern Med 167:591-6. 2007.... - Adherence with intravenous zoledronate and intravenous ibandronate in the United States Medicare populationJeffrey R Curtis
University of Alabama at Birmingham, AL, USA
Arthritis Care Res (Hoboken) 64:1054-60. 2012..To evaluate adherence to drug therapy among new users of zoledronate and intravenous (IV) ibandronate among US Medicare enrollees... - Regional variation in the denial of reimbursement for bone mineral density testing among US Medicare beneficiariesJeffrey R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Clin Densitom 11:568-74. 2008..Greater guidance and transparency in coding policies are needed to ensure that DXA as a covered service is reimbursed for Medicare beneficiaries with the appropriate indications... - Is withholding osteoporosis medication after fracture sometimes rational? A comparison of the risk for second fracture versus deathJeffrey R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Am Med Dir Assoc 11:584-91. 2010..Among US Medicare beneficiaries, we evaluated the risk for second fracture versus death in the 5 years following a hip, clinical vertebral, and wrist/forearm fracture... - The delivery of evidence-based preventive care for older Americans with arthritisJeffrey R Curtis
Department of Medicine, University of Alabama, Birmingham, Birmingham, AL 35294, USA
Arthritis Res Ther 12:R144. 2010..We evaluated the proportion of older Americans with RA, psoriatic arthritis (PsA), and osteoarthritis (OA) receiving these services and the specialty of the providers delivering this care... - Administrative codes combined with medical records based criteria accurately identified bacterial infections among rheumatoid arthritis patientsNivedita M Patkar
Center for Education and Research on Therapeutics of Musculoskeletal Disorders, University of Alabama at Birmingham, Birmingham, AL 35294 3408, USA
J Clin Epidemiol 62:321-7, 327.e1-7. 2009..To evaluate diagnostic properties of International Classification of Diseases, Version 9 (ICD-9) diagnosis codes and infection criteria to identify bacterial infections among rheumatoid arthritis (RA) patients... - Validation of diagnostic codes for subtrochanteric, diaphyseal, and atypical femoral fractures using administrative claims dataPongthorn Narongroeknawin
Department of Medicine, University of Alabama, Birmingham, AL, USA
J Clin Densitom 15:92-102. 2012..These claims algorithms will be useful in future population-based observational studies to evaluate associations between osteoporosis medications and subtrochanteric and diaphyseal femoral fractures... - Osteoporosis in the home health care setting: A window of opportunity?Jeffrey R Curtis
University of Alabama at Birmingham, Birmingham, AL 35294, USA
Arthritis Rheum 55:971-5. 2006 - Biologics and heart failure in rheumatoid arthritis: are we any wiser?Maria I Danila
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
Curr Opin Rheumatol 20:327-33. 2008.... - Benefit of adherence with bisphosphonates depends on age and fracture type: results from an analysis of 101,038 new bisphosphonate usersJeffrey R Curtis
Center for Education and Research on Therapeutics, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Bone Miner Res 23:1435-41. 2008..These results provide estimates of absolute fracture effectiveness across age subgroups and fracture types that have been minimally evaluated in clinical trials and may be useful for future cost-effectiveness studies... - Racial disparities in osteoporosis prevention in a managed care populationAmy S Mudano
Department of Medicine and Center for Education and Research on Therapeutics of Musculoskeletal Disorders, Division of Continuing Medical Education, University of Alabama at Birmingham, 35294-3408, USA
South Med J 96:445-51. 2003..CONCLUSION: Compared with whites, black women reported significantly less BMD testing and prescription and nonprescription osteoporosis therapy. This disparity was not fully explained by other demographic or risk factor differences... - A group randomized trial to improve safe use of nonsteroidal anti-inflammatory drugsJeffrey R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Am J Manag Care 11:537-43. 2005..Potentially contributing factors include high baseline performance (ceiling effect), dilution of the intervention effect by case mix and provider factors, nonreceipt of intervention materials, and diverse indications for lab tests... - Does medication adherence itself confer fracture protection? An investigation of the healthy adherer effect in observational dataJeffrey R Curtis
University of Alabama at Birmingham, Birmingham, AL 35294, USA
Arthritis Care Res (Hoboken) 64:1855-63. 2012.... - Improving osteoporosis care in high-risk home health patients through a high-intensity interventionRyan C Outman
Department of Medicine, Division of Immunology and Rheumatology, University of Alabama at Birmingham, FOT 820, 1530 3rd Ave S, Birmingham, AL 35294, United States
Contemp Clin Trials 33:206-12. 2012..We developed and tested a multi-modal intervention, delivered in the home health care setting, aimed at increasing osteoporosis treatment rates to prevent fractures... - Ethnic variations in the prevalence of metabolic bone disease among HIV-positive patients with lipodystrophyJeffrey R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 510 20th Street South, Birmingham, AL 35294, USA
AIDS Res Hum Retroviruses 22:125-31. 2006..Studies to examine ethnic variations in bone metabolism are necessary to devise optimal interventions... - Health care expenditures associated with skeletal fractures among Medicare beneficiaries, 1999-2005Meredith L Kilgore
Department of Health Care Organization and Policy, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Bone Miner Res 24:2050-5. 2009..Further research is needed to ascertain other health conditions that are driving costs for Medicare beneficiaries after fractures... - Risk of serious bacterial infections among rheumatoid arthritis patients exposed to tumor necrosis factor alpha antagonistsJeffrey R Curtis
University of Alabama at Birmingham, Center for Education and Research on Therapeutics, AL 35294, USA
Arthritis Rheum 56:1125-33. 2007..To evaluate the risk of serious bacterial infections associated with tumor necrosis factor alpha (TNFalpha) antagonists among rheumatoid arthritis (RA) patients... - Recent trends in hip fracture rates by race/ethnicity among older US adultsNicole C Wright
Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA
J Bone Miner Res 27:2325-32. 2012..Further research is needed to understand mechanisms responsible for declining rates in some and not others, as hip fractures continue to be a major problem among the elderly. © 2012 American Society for Bone and Mineral Research... - Longitudinal trends in use of bone mass measurement among older americans, 1999-2005Jeffrey R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Bone Miner Res 23:1061-7. 2008..Given the importance of central DXA to assess the risk of osteoporotic fractures, strategies to increase central DXA use to test at-risk persons are warranted... - The comparative risk of serious infections among rheumatoid arthritis patients starting or switching biological agentsJeffrey R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
Ann Rheum Dis 70:1401-6. 2011..This study evaluated the incidence of hospitalised infections among rheumatoid arthritis (RA) patients starting or switching various biological agents... - From fracture risk prediction to evaluating fracture patterns: recent advances in the epidemiology of osteoporosisNicole C Wright
Department of Epidemiology, University of Alabama at Birmingham, 35294, USA
Curr Rheumatol Rep 14:205-11. 2012..We also discuss recent evaluations of secular trends in fracture incidence... - Association of infections and tuberculosis with antitumor necrosis factor alpha therapyNivedita M Patkar
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama 35294 3408, USA
Curr Opin Rheumatol 20:320-6. 2008..We present recent literature on this topic with a focus on clinical applications of this new data... - The epidemiology of glucocorticoid-associated adverse eventsAllyson K McDonough
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, 510 20th Street South, Birmingham, AL 35213, USA
Curr Opin Rheumatol 20:131-7. 2008..The purpose of this review is to provide an update on the most recent literature regarding glucocorticoid use and associated adverse events... - The association of race/ethnicity with the receipt of traditional and alternative arthritis-specific health careTed R Mikuls
Department of Medicine, Section of Rheumatology and Immunology, University of Nebraska Medical Center and the Omaha VA Medical Center, Omaha, Nebraska, USA
Med Care 41:1233-9. 2003.... - Racial disparities in the receipt of osteoporosis related healthcare among community-dwelling older women with arthritis and previous fractureTed R Mikuls
Department of Medicine, Section of Rheumatology and Immunology, University of Nebraska Medical Center, Omaha, Nebraska 68198 3025, USA
J Rheumatol 32:870-5. 2005..To examine potential racial/ethnic disparities in osteoporosis care among community-dwelling older women with self-reported arthritis and previous fracture... - Heart failure among younger rheumatoid arthritis and Crohn's patients exposed to TNF-alpha antagonistsJ R Curtis
Center for Education and Research on Therapeutics of Musculoskeletal Disorders, The University of Alabama at Birmingham, Birmingham, AL, USA
Rheumatology (Oxford) 46:1688-93. 2007..HF clinical trials of these agents were stopped early due to futility or worsening of existing HF. A potential association between etanercept and infliximab and new onset HF has been studied minimally at a population level... - Gout epidemiology: results from the UK General Practice Research Database, 1990-1999T R Mikuls
Department of Medicine, University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, USA
Ann Rheum Dis 64:267-72. 2005..CONCLUSION: Although gout is common in the UK, particularly among older men, the incidence of the disease seems to have remained stable during the 1990s... - A randomized trial of a mailed intervention and self-scheduling to improve osteoporosis screening in postmenopausal womenAmy H Warriner
Division of Endocrinology, Diabetes and Metabolism, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Bone Miner Res 27:2603-10. 2012..This simple approach may be an effective component of a multifaceted quality improvement program to increase rates of osteoporosis screening... - Drug treatment of hyperuricemia to prevent cardiovascular outcomes: are we there yet?Angelo L Gaffo
Birmingham VA Medical Center, Birmingham, AL 35294, USA
Am J Cardiovasc Drugs 12:1-6. 2012.... - Serum urate and its relationship with alcoholic beverage intake in men and women: findings from the Coronary Artery Risk Development in Young Adults (CARDIA) cohortAngelo L Gaffo
Birmingham Veterans Affairs Medical Center, University of Alabama at Birmingham, USA
Ann Rheum Dis 69:1965-70. 2010..To investigate if beer, liquor (spirits), wine and total alcohol intakes have different associations with serum urate (SU) concentrations at different ages in a cohort of young men and women... - Developing a provisional definition of flare in patients with established goutAngelo L Gaffo
Birmingham VA Medical Center and University of Alabama at Birmingham, AL, USA
Arthritis Rheum 64:1508-17. 2012..Various nonvalidated criteria for disease flare have been used in studies of gout. Our objective was to develop empirical definitions for a gout flare from patient-reported features... - Medication errors with the use of allopurinol and colchicine: a retrospective study of a national, anonymous Internet-accessible error reporting systemTed R Mikuls
Department of Medicine, University of Nebraska Medical Center, Omaha, USA
J Rheumatol 33:562-6. 2006..Physician prescribing practices are a potential target for quality improvement interventions in gout care... - Bone mineral density changes within six months of renal transplantationTed R Mikuls
Section of Rheumatology and Immunology, Department of Medicine, University of Nebraska Medical Center, USA
Transplantation 75:49-54. 2003..Lumbar bone loss seemed to be mediated primarily by glucocorticoid dose and a history of alcohol use... - Treatment of rheumatoid arthritisAngelo Gaffo
Center for Education and Research and Therapeutics of Musculoskeletal Diseases, University of Alabama at Birmingham, Birmingham, AL, USA
Am J Health Syst Pharm 63:2451-65. 2006.... - Potential and pitfalls of using large administrative claims data to study the safety of osteoporosis therapiesJie Zhang
Department of Epidemiology and Health Services Comparative Effectiveness Research Training Program, University of Alabama at Birmingham, 1665 University Boulevard, RPHB 517B, Birmingham, AL 35294, USA
Curr Rheumatol Rep 13:273-82. 2011.... - Long-term safety concerns of antiresorptive therapyJie Zhang
Health Services Comparative Effectiveness Research Training Program, Department of Epidemiology, University of Alabama at Birmingham, 1665 University Boulevard, RPHB 517B, Birmingham, AL 35294, USA
Rheum Dis Clin North Am 37:387-400, vi. 2011..This review summarizes studies examining the association between bisphosphonate use and these adverse outcomes, with a focus on large case series and controlled epidemiologic studies... - Quality health care gaps in osteoporosis: how can patients, providers, and the health system do a better job?Gim Gee Teng
Center for Education and Research on Therapeutics of Musculoskeletal Disorders, and Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 510 20th Street South, Birmingham, AL 35294 3708, USA
Curr Osteoporos Rep 7:27-34. 2009..Methods to improve quality of care in osteoporosis need to be multipronged, with emphasis on clinical process improvement and reliance on interdisciplinary teams. We review the growing literature on quality of care for osteoporosis... - Pathophysiology, clinical presentation and treatment of goutGim Gee Teng
Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama 35294-3296, USA
Drugs 66:1547-63. 2006.... - Osteoporosis: evaluation and treatmentSonia Bajaj
Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 820 Faculty Office Tower, 510 20th Street South, Birmingham, AL 35294-3408, USA
Curr Womens Health Rep 3:418-24. 2003..This increasing range of treatment options allows better matching of therapy to patients... - American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritisKenneth G Saag
University of Alabama, Birmingham, AL, USA
Arthritis Rheum 59:762-84. 2008 - Using a modified nominal group technique to elicit director of nursing input for an osteoporosis interventionDeborah A Levine
Deep South Center on Effectiveness Research, An HSR and D REAP, Birmingham VA Medical Center, Birmingham, AL, USA
J Am Med Dir Assoc 7:420-5. 2006..Barriers prevent osteoporosis care in nursing homes. Successful interventions designed to circumvent these barriers benefit from target recipient input during development... - Improving quality of care in osteoporosis: opportunities and challengesGim Gee Teng
Center for Education and Research on Therapeutics CERTs of Musculoskeletal Disorders, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 820 Faculty Office Tower, 510 20th Street South, Birmingham, AL 35294 3708, USA
Curr Rheumatol Rep 10:123-30. 2008..Recent studies have indicated that restructuring care at the system level is more likely to be successful, dependable, and durable than traditional quality improvement interventions focusing predominantly on physicians... - Comorbidity in rheumatoid arthritisT R Mikuls
Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, Alabama, USA
Rheum Dis Clin North Am 27:283-303. 2001..The next decade should prove to be an exciting time in RA management. Better identification, understanding, and management of RA comorbidities have great potential to improve quality of life and survival among our patients with RA... - Cost-effectiveness of multifaceted evidence implementation programs for the prevention of glucocorticoid-induced osteoporosisT Beukelman
University of Alabama at Birmingham, Deep South Musculoskeletal Center for Education and Research on Therapeutics, Birmingham, AL 35294 3408, USA
Osteoporos Int 21:1573-84. 2010.... - Do physicians within the same practice setting manage osteoporosis patients similarly? Implications for implementation researchJ R Curtis
Center for Education and Research on Therapeutics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Osteoporos Int 20:1921-7. 2009..We found no significant clustering effect for common practice setting, suggesting that osteoporosis quality improvement (QI) efforts may be able to ignore this factor in designing QI interventions... - Mortality risk associated with rheumatoid arthritis in a prospective cohort of older women: results from the Iowa Women's Health StudyT R Mikuls
Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, 35294, USA
Ann Rheum Dis 61:994-9. 2002..To determine whether rheumatoid arthritis (RA) is associated with excess mortality among older women... - Channeling and adherence with alendronate and risedronate among chronic glucocorticoid usersJ R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, FOT 820, 510 20th Street South, 35294, USA
Osteoporos Int 17:1268-74. 2006..Newer strategies to promote long-term adherence are needed to improve osteoporosis therapeutic effectiveness... - Estimated prevalence and patterns of presumed osteoporosis among older Americans based on Medicare dataH Cheng
Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA
Osteoporos Int 20:1507-15. 2009..Estimates of osteoporosis (OP) prevalence based on bone mineral density testing and fracture occurrence may be imprecise for small demographic groups. Medicare data are a useful supplemental source of information on OP... - "Pathologic" fractures: should these be included in epidemiologic studies of osteoporotic fractures?J R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA
Osteoporos Int 20:1969-72. 2009..Among these, 48% (vertebral) and 3% (hip) of the fractures were coded as pathologic. Only 25% and 66% of persons with these pathologic fractures had evidence for malignancy... - The geographic availability and associated utilization of dual-energy X-ray absorptiometry (DXA) testing among older persons in the United StatesJ R Curtis
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA
Osteoporos Int 20:1553-61. 2009..After adjusting for potentially confounding factors, travel distance was strongly associated with DXA testing. Rural residents were most strongly dependent on the availability of DXAs performed in physician offices... - Risk of hip fracture after bisphosphonate discontinuation: implications for a drug holidayJ R Curtis
Center for Education and Research on Therapeutics of Musculoskeletal Disorders, University of Alabama at Birmingham, Birmingham, AL, USA
Osteoporos Int 19:1613-20. 2008.... - Confirmation of administrative claims-identified opportunistic infections and other serious potential adverse events associated with tumor necrosis factor alpha antagonists and disease-modifying antirheumatic drugsJ R Curtis
University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Arthritis Rheum 57:343-6. 2007 - RisedronatE and ALendronate Intervention over Three Years (REALITY): minimal differences in fracture risk reductionJ R Curtis
Center for Education and Research on Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA
Osteoporos Int 20:973-8. 2009..We conclude that the agents have comparable efficacy... - Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?Angelo L Gaffo
Birmingham VA Medical Center, 700 19th St S, Birmingham, AL 35233, USA
Arthritis Res Ther 11:240. 2009..In this review we present recently published data that study the association between hyperuricemia and selected cardiovascular diseases, with a final conclusion about the possibility of this association being causal... - The effect of thiazolidinediones on BMD and osteoporosisAllyson K McDonough
University of Alabama at Birmingham, Division of Clinical Immunology Rheumatology, FOT 820D, 1530 3rd Avenue South, Birmingham, AL 35294 3408, USA
Nat Clin Pract Endocrinol Metab 4:507-13. 2008.... - Postmenopausal osteoporosis. What have we learned since the introduction of bisphosphonates?Sumapa Chaiamnuay
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA
Rev Endocr Metab Disord 7:101-12. 2006..Newer safety concerns about the use of bisphosphonates include osteonecrosis of the jaw and oversuppression of bone turnover. The optimal duration of bisphosphonate treatment has not been clearly established... - Unbalanced regulation of over-the-counter analgesics: the lesser of two evils?Jeroan J Allison
Center for Education and Research on Therapeutics CERTs of Musculoskeletal Disorders, University of Alabama at Birmingham, Birmingham, Alberta, Canada
Pharmacoepidemiol Drug Saf 15:410-1. 2006 - Management of hyperuricemia and gout in CKDAngelo L Gaffo
Birmingham VA Medical Center, University of Alabama at Birmingham, AL, USA
Am J Kidney Dis 52:994-1009. 2008 - Glucocorticoid use in rheumatoid arthritis: benefits, mechanisms, and risksH B Townsend
Center for Education and Research on Therapeutics of Musculoskeletal Disorders, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham 35294-3408, USA
Clin Exp Rheumatol 22:S77-82. 2004..In this review we will examine the latest data supporting the benefits and risks of glucocorticoid use in RA... - The cost of glucocorticoid-associated adverse events in rheumatoid arthritisM Pisu
Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 1530 3rd Avenue North, Birmingham, AL 35294-3408, USA
Rheumatology (Oxford) 44:781-8. 2005..Patients, providers and policy makers should consider these potential costs of GAEs when making treatment decisions... - Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritisL B Hughes
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 415 Lyons Harrison Research Building, Birmingham, AL 35294 0007, USA
Ann Rheum Dis 65:1213-8. 2006..The anti-folate drug methotrexate (MTX) is commonly used to treat rheumatoid arthritis... - Smoking interacts with genetic risk factors in the development of rheumatoid arthritis among older Caucasian womenL A Criswell
Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California, San Francisco, CA, USA
Ann Rheum Dis 65:1163-7. 2006..To determine whether the impact of tobacco exposure on rheumatoid arthritis (RA) risk is influenced by polymorphisms at the HLA-DRB1 and glutathione S-transferase M1 (GSTM1) loci... - Impact of osteoporosis treatment adherence on fracture rates in North America and EuropeEthel S Siris
Toni Stabile Osteoporosis Center, Department of Medicine, Columbia University Medical Center, New York, New York 10032, USA
Am J Med 122:S3-13. 2009.... - Coffee, tea, and caffeine consumption and risk of rheumatoid arthritis: results from the Iowa Women's Health StudyTed R Mikuls
University of Alabama at Birmingham, 35294-3296, USA
Arthritis Rheum 46:83-91. 2002..Further investigations of decaffeinated coffee and tea intake as arthritis risk factors are needed to verify these findings and explore their biologic basis... - Samarium-153-EDTMP in the treatment of refractory rheumatoid arthritisT R Mikuls
Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, USA
Scand J Rheumatol 30:356-9. 2001..Sm-153, at doses of 0.5 and 1.0 mCi/kg, is well tolerated but minimally effective in the treatment of refractory RA as measured using ACR response criteria... - Challenges in defining and improving osteoporosis quality of careA Warriner
Center for Education and Research on Therapeutics CERTs of Musculoskeletal Disorders, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL 35294 3708, USA
Clin Exp Rheumatol 25:142-6. 2007..In order to overcome these barriers, interventions that can be widely disseminated, cost-effective and influential at multiple levels are needed... - Vertebroplasty and kyphoplasty are associated with an increased risk of secondary vertebral compression fractures: a population-based cohort studyA S Mudano
Center for Education and Research on Therapeutics CERTs of Musculoskeletal Disorders, University of Alabama at Birmingham, Birmingham, AL 35294 3408, USA
Osteoporos Int 20:819-26. 2009..The risk of subsequent fracture was significantly greater among treatment patients, especially within 90 days of the procedure...