W A Rutala

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi request reprint How to assess risk of disease transmission to patients when there is a failure to follow recommended disinfection and sterilization guidelines
    William A Rutala
    Department of Hospital Epidemiology, University of North Carolina at Chapel Hill, NC 27599, USA
    Infect Control Hosp Epidemiol 28:146-55. 2007
  2. ncbi request reprint The benefits of surface disinfection
    William A Rutala
    Am J Infect Control 33:434-5. 2005
  3. doi request reprint Room decontamination with UV radiation
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care, and the Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    Infect Control Hosp Epidemiol 31:1025-9. 2010
  4. doi request reprint Effectiveness of improved hydrogen peroxide in decontaminating privacy curtains contaminated with multidrug-resistant pathogens
    William A Rutala
    Hospital Epidemiology, Occupational Health and Safety Program, University of North Carolina Health Care, Chapel Hill, NC Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC Electronic address
    Am J Infect Control 42:426-8. 2014
  5. doi request reprint New developments in reprocessing semicritical items
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27599 7030, USA
    Am J Infect Control 41:S60-6. 2013
  6. doi request reprint Disinfectants used for environmental disinfection and new room decontamination technology
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27599 7030, USA
    Am J Infect Control 41:S36-41. 2013
  7. doi request reprint Disinfection and sterilization: an overview
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27599 7030, USA
    Am J Infect Control 41:S2-5. 2013
  8. doi request reprint Efficacy of improved hydrogen peroxide against important healthcare-associated pathogens
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, North Carolina, USA
    Infect Control Hosp Epidemiol 33:1159-61. 2012
  9. ncbi request reprint Disinfection and sterilization in health care facilities: what clinicians need to know
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27599 7030, USA
    Clin Infect Dis 39:702-9. 2004
  10. pmc Efficacy of hospital germicides against adenovirus 8, a common cause of epidemic keratoconjunctivitis in health care facilities
    William A Rutala
    Department of Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27514, USA
    Antimicrob Agents Chemother 50:1419-24. 2006

Collaborators

Detail Information

Publications56

  1. ncbi request reprint How to assess risk of disease transmission to patients when there is a failure to follow recommended disinfection and sterilization guidelines
    William A Rutala
    Department of Hospital Epidemiology, University of North Carolina at Chapel Hill, NC 27599, USA
    Infect Control Hosp Epidemiol 28:146-55. 2007
    ..Disinfection and sterilization are critical components of infection control. Unfortunately, breaches of disinfection and sterilization guidelines are not uncommon...
  2. ncbi request reprint The benefits of surface disinfection
    William A Rutala
    Am J Infect Control 33:434-5. 2005
  3. doi request reprint Room decontamination with UV radiation
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care, and the Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    Infect Control Hosp Epidemiol 31:1025-9. 2010
    ..To determine the effectiveness of a UV-C-emitting device to eliminate clinically important nosocomial pathogens in a contaminated hospital room...
  4. doi request reprint Effectiveness of improved hydrogen peroxide in decontaminating privacy curtains contaminated with multidrug-resistant pathogens
    William A Rutala
    Hospital Epidemiology, Occupational Health and Safety Program, University of North Carolina Health Care, Chapel Hill, NC Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC Electronic address
    Am J Infect Control 42:426-8. 2014
    ..The microbial contamination of the curtains was assessed before and after the curtains were sprayed with improved hydrogen peroxide. The disinfectant reduced the microbial load on the privacy curtains by 96.8% in 37 patient rooms. ..
  5. doi request reprint New developments in reprocessing semicritical items
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27599 7030, USA
    Am J Infect Control 41:S60-6. 2013
    ..Strict adherence to current guidelines is required because more outbreaks have been linked to inadequately cleaned or disinfected endoscopes undergoing high-level disinfection than any other medical device...
  6. doi request reprint Disinfectants used for environmental disinfection and new room decontamination technology
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27599 7030, USA
    Am J Infect Control 41:S36-41. 2013
    ..Room decontamination units (such as ultraviolet-C and hydrogen peroxide systems) aid in reducing environmental contamination after terminal room cleaning and disinfection...
  7. doi request reprint Disinfection and sterilization: an overview
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27599 7030, USA
    Am J Infect Control 41:S2-5. 2013
    ..Cleaning must always precede high-level disinfection and sterilization...
  8. doi request reprint Efficacy of improved hydrogen peroxide against important healthcare-associated pathogens
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, North Carolina, USA
    Infect Control Hosp Epidemiol 33:1159-61. 2012
    ..Improved HP is significantly superior to standard HP at the same concentration and can be used for disinfection of environmental surfaces or noncritical patient care items...
  9. ncbi request reprint Disinfection and sterilization in health care facilities: what clinicians need to know
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27599 7030, USA
    Clin Infect Dis 39:702-9. 2004
    ..Adherence to these recommendations should improve disinfection and sterilization practices in health care facilities, thereby reducing infections associated with contaminated patient-care items...
  10. pmc Efficacy of hospital germicides against adenovirus 8, a common cause of epidemic keratoconjunctivitis in health care facilities
    William A Rutala
    Department of Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27514, USA
    Antimicrob Agents Chemother 50:1419-24. 2006
    ....
  11. ncbi request reprint Bacterial contamination of keyboards: efficacy and functional impact of disinfectants
    William A Rutala
    Department of Hospital Epidemiology, University of North Carolina Health Care System, 130 Mason Farm Road, Chapel Hill, NC 27599, USA
    Infect Control Hosp Epidemiol 27:372-7. 2006
    ..This study was performed to determine the degree of microbial contamination, the efficacy of different disinfectants, and the cosmetic and functional effects of the disinfectants on the computer keyboards...
  12. ncbi request reprint Disinfection of a probe used in ultrasound-guided prostate biopsy
    William A Rutala
    Department of Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC, USA
    Infect Control Hosp Epidemiol 28:916-9. 2007
    ..Transrectal ultrasound (TRUS)-guided prostate biopsies are among the most common outpatient diagnostic procedures in urology clinics and carry the risk of introducing pathogens that may lead to infection...
  13. ncbi request reprint Microbiologic evaluation of microfiber mops for surface disinfection
    William A Rutala
    Department of Hospital Epidemiology, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    Am J Infect Control 35:569-73. 2007
    ..Recently, health care facilities have started to use a microfiber mopping technique rather than a conventional, cotton string mop to clean floors...
  14. doi request reprint Impact of an oil-based lubricant on the effectiveness of the sterilization processes
    William A Rutala
    Department of Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, North Carolina 27599 7030, USA
    Infect Control Hosp Epidemiol 29:69-72. 2008
    ....
  15. doi request reprint Sterilization, high-level disinfection, and environmental cleaning
    William A Rutala
    Department of Hospital Epidemiology, University of North Carolina Health Care, Chapel Hill, 101 Manning Drive, NC 27514, USA
    Infect Dis Clin North Am 25:45-76. 2011
    ..In addition, current issues and practices associated with environmental cleaning are reviewed...
  16. ncbi request reprint Reprocessing endoscopes: United States perspective
    W A Rutala
    Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27514, USA
    J Hosp Infect 56:S27-39. 2004
    ....
  17. pmc New disinfection and sterilization methods
    W A Rutala
    University of North Carolina UNC Health Care System and UNC School of Medicine, Chapel Hill, North Carolina, USA
    Emerg Infect Dis 7:348-53. 2001
    ....
  18. ncbi request reprint Levels of microbial contamination on surgical instruments
    W A Rutala
    Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, USA
    Am J Infect Control 26:143-5. 1998
    ..This suggests that new low-temperature sterilization technologies are likely to be highly effective in preventing cross-transmission of infection via nonlumen medical instruments...
  19. ncbi request reprint Surface disinfection: should we do it?
    W A Rutala
    Division of Infectious Diseases, University of North Carolina Health Care System, UNC School of Medicine, Chapel Hill 27514, USA
    J Hosp Infect 48:S64-8. 2001
    ..It concludes that while non-critical surfaces are uncommonly associated with transmission of infections to patients, one should clean and disinfect surfaces on a regularly scheduled basis...
  20. pmc Uses of inorganic hypochlorite (bleach) in health-care facilities
    W A Rutala
    Division of Infectious Diseases, University of North Carolina School of Medicine, USA
    Clin Microbiol Rev 10:597-610. 1997
    ..Despite the increasing availability of other disinfectants, hypochlorites continue to find wide use in hospitals...
  21. ncbi request reprint The effects of test variables on the efficacy of hand hygiene agents
    Emily E Sickbert-Bennett
    Department of Hospital Epidemiology, University of North Carolina Healthcare System, Chapel Hill, NC 27514, USA
    Am J Infect Control 32:69-83. 2004
    ..The purpose of this study was to evaluate the effect of test variables on the efficacy of hand hygiene agents...
  22. ncbi request reprint Faucet aerators: A source of patient colonization with Stenotrophomonas maltophilia
    D J Weber
    Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill 27599 7030, USA
    Am J Infect Control 27:59-63. 1999
    ..If additional clusters of infected or colonized patients are linked to contaminated aerators, consideration should be given to routine disinfection or removal of the aerators...
  23. ncbi request reprint The benefits of surface disinfection
    William A Rutala
    University of North Carolina Health Care System, Chapel Hill, USA
    Am J Infect Control 32:226-31. 2004
  24. ncbi request reprint Microbiology of ventilator-associated pneumonia compared with that of hospital-acquired pneumonia
    David J Weber
    Department of Hospital Epidemiology, University of North Carolina Health Care System, University of North Carolina School of Medicine, Chapel Hill, NC, 27599, USA
    Infect Control Hosp Epidemiol 28:825-31. 2007
    ..This evaluation assessed whether the currently recommended empirical therapy is appropriate for both ventilator-associated pneumonia (VAP) and HAP by evaluating the infecting flora...
  25. pmc Outbreaks associated with contaminated antiseptics and disinfectants
    David J Weber
    Department of Hospital Epidemiology, University of North Carolina Health Care System, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7030, USA
    Antimicrob Agents Chemother 51:4217-24. 2007
  26. ncbi request reprint Immunization of immunocompromised persons
    David J Weber
    Adult Infectious Disease Division, University of North Carolina School of Medicine, CB 7030, Bioinformatics Building, 130 Mason Farm Road, Chapel Hill, NC 27599 7030, USA
    Immunol Allergy Clin North Am 23:605-34, v-vi. 2003
    ..This article reviews the benefits of and risks for immunization in immunocompromised persons and provides recommendations for the use of specific vaccines...
  27. ncbi request reprint Comparison of hospitalwide surveillance and targeted intensive care unit surveillance of healthcare-associated infections
    David J Weber
    Department of Hospital Epidemiology, University of North Carolina Health Care System, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    Infect Control Hosp Epidemiol 28:1361-6. 2007
    ..In addition, we assessed whether the infection rates in step-down units more resemble those in wards or ICUs...
  28. doi request reprint Role of hospital surfaces in the transmission of emerging health care-associated pathogens: norovirus, Clostridium difficile, and Acinetobacter species
    David J Weber
    Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Am J Infect Control 38:S25-33. 2010
    ..Current hand hygiene guidelines and recommendations for surface cleaning/disinfection should be followed in managing outbreaks because of these emerging pathogens...
  29. doi request reprint Preventing healthcare-associated Aspergillus infections: review of recent CDC/HICPAC recommendations
    David J Weber
    Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, NC 27599 7030, USA
    Med Mycol 47:S199-209. 2009
    ....
  30. doi request reprint Control of healthcare-associated Staphylococcus aureus: Survey of practices in North Carolina hospitals
    David J Weber
    University of North Carolina, Department of Hospital Epidemiology, Chapel Hill, USA
    Infect Control Hosp Epidemiol 30:909-11. 2009
    ..We report here the results of a survey of 70 hospitals in North Carolina with regard to current management issues surrounding methicillin-resistant S. aureus...
  31. pmc Effects of air temperature and relative humidity on coronavirus survival on surfaces
    Lisa M Casanova
    Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Appl Environ Microbiol 76:2712-7. 2010
    ..TGEV and MHV could serve as conservative surrogates for modeling exposure, the risk of transmission, and control measures for pathogenic enveloped viruses, such as SARS-CoV and influenza virus, on health care surfaces...
  32. doi request reprint A quantitative approach to defining "high-touch" surfaces in hospitals
    Kirk Huslage
    Department of Hospital Epidemiology, UNC Health Care, University of North Carolina, Chapel Hill, North Carolina 27514, USA
    Infect Control Hosp Epidemiol 31:850-3. 2010
    ..Five surfaces were defined as high-touch surfaces: the bed rails, the bed surface, the supply cart, the over-bed table, and the intravenous pump...
  33. ncbi request reprint Compliance with isolation precautions at a university hospital
    David J Weber
    Department of Hospital Epidemiology, University of North Carolina Health Care System, Chapel Hill, NC 27599, USA
    Infect Control Hosp Epidemiol 28:358-61. 2007
    ..5% (13 observations); contact isolation, 73.3% (165 observations); and protective isolation, 73.6% (72 observations). As with hand hygiene, there is suboptimal compliance with recommended isolation precautions...
  34. ncbi request reprint Efficacy of selected hand hygiene agents used to remove Bacillus atrophaeus (a surrogate of Bacillus anthracis) from contaminated hands
    David J Weber
    Division of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill CB 7030, 130 Mason Farm Rd, Chapel Hill, NC 27599 7030, USA
    JAMA 289:1274-7. 2003
    ..However, only limited data are available on the susceptibility of B anthracis to antiseptics...
  35. doi request reprint Survival of surrogate coronaviruses in water
    Lisa Casanova
    Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, NC 27599, USA
    Water Res 43:1893-8. 2009
    ..Coronaviruses can remain infectious for long periods in water and pasteurized settled sewage, suggesting contaminated water is a potential vehicle for human exposure if aerosols are generated...
  36. ncbi request reprint Comparative efficacy of hand hygiene agents in the reduction of bacteria and viruses
    Emily E Sickbert-Bennett
    Department of Hospital Epidemiology, University of North Carolina Health Care System, North Carolina, USA
    Am J Infect Control 33:67-77. 2005
    ..Health care-associated infections most commonly result from person-to-person transmission via the hands of health care workers...
  37. ncbi request reprint Lessons learned from a norovirus outbreak in a locked pediatric inpatient psychiatric unit
    David J Weber
    Department of Hospital Epidemiology, University of North Carolina Health Care System, USA
    Infect Control Hosp Epidemiol 26:841-3. 2005
    ..Factors contributing to the outbreak included environmental contamination, close staff-patient contact including sharing meals, and inability to confine the index patient with the use of contact precautions...
  38. doi request reprint Central line-associated bloodstream infections: prevention and management
    David J Weber
    Division of Infectious Diseases, University of North Carolina School of Medicine, 2163 Bioinformatics, 130 Mason Farm Road, Chapel Hill, NC 27599 7030, USA
    Infect Dis Clin North Am 25:77-102. 2011
    ....
  39. ncbi request reprint Creutzfeldt-Jakob disease: recommendations for disinfection and sterilization
    W A Rutala
    Division of Infectious Diseases, University of North Carolina (UNC) School of Medicine and the Department of Hospital Epidemiology, UNC Health Care System, Chapel Hill, NC 27599-7030, USA
    Clin Infect Dis 32:1348-56. 2001
    ..g., surgical instruments) and semicritical devices contaminated with high-risk tissue (i.e., brain, spinal cord, and eye tissue) from high-risk patients--those with known or suspected infection with CJD--require special treatment...
  40. ncbi request reprint Clinical effectiveness of low-temperature sterilization technologies
    W A Rutala
    University of North Carolina School of Medicine, the Department of Hospital Epidemiology, UNC Hospitals, Chapel Hill 27599 7030, USA
    Infect Control Hosp Epidemiol 19:798-804. 1998
    ....
  41. ncbi request reprint Risks and prevention of nosocomial transmission of rare zoonotic diseases
    D J Weber
    Division of Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7030, USA
    Clin Infect Dis 32:446-56. 2001
    ..Adherence to recommended isolation precautions will allow for proper patient care while protecting the health care workers who provide care to patients with known or suspected zoonotic infections capable of nosocomial transmission...
  42. ncbi request reprint Pseudomonas aeruginosa-related postoperative endophthalmitis linked to a contaminated phacoemulsifier
    Karen K Hoffmann
    University of North Carolina at Chapel Hill, Campus Box 7030, Burnett Womack, Room 547, Chapel Hill, NC 27599 7030, USA
    Arch Ophthalmol 120:90-3. 2002
  43. ncbi request reprint Use of germicides in the home and the healthcare setting: is there a relationship between germicide use and antibiotic resistance?
    David J Weber
    Division of Infectious Disease, University of North Carolina School of Medicine, hapel Hill, NC 27599 7030, USA
    Infect Control Hosp Epidemiol 27:1107-19. 2006
    ..The spread of antibiotic-resistant pathogens represents an increasing threat in healthcare facilities. Concern has been expressed that the use of surface disinfectants and antiseptics may select for antibiotic-resistant pathogens...
  44. ncbi request reprint The emerging nosocomial pathogens Cryptosporidium, Escherichia coli O157:H7, Helicobacter pylori, and hepatitis C: epidemiology, environmental survival, efficacy of disinfection, and control measures
    D J Weber
    Department of Medicine, University of North Carolina at Chapel Hill, 27599-7030, USA
    Infect Control Hosp Epidemiol 22:306-15. 2001
    ....
  45. doi request reprint Lessons learned: protection of healthcare workers from infectious disease risks
    David J Weber
    Department of Medicine, University of North Carolina at Chapel Hill, NC, USA
    Crit Care Med 38:S306-14. 2010
    ..To summarize current concepts on preventing occupationally acquired infections in healthcare workers...
  46. ncbi request reprint Managing the risk of nosocomial transmission of prion diseases
    David J Weber
    Division of Infectious Diseases, University of North Carolina UNC School of Medicine, Chapel Hill, USA
    Curr Opin Infect Dis 15:421-5. 2002
    ..This paper reviews the recent literature and provides recommendations for the prevention of nosocomial transmission of prion agents...
  47. ncbi request reprint Multi-use Venturi nasal atomizer contamination in a clinical rhinologic practice
    Marc G Dubin
    Department of Otolaryngology Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Am J Rhinol 18:151-6. 2004
    ..Cross-contamination of Venturi atomizers has been reported...
  48. ncbi request reprint Registration of disinfectants based on relative microbicidal activity
    William A Rutala
    Division of Infectious Disease, University of North Carolina UNC School of Medicine, Department of Hospital Epidemiology, MPH, CB 7030 Bioinformatics Building, 130 Mason Farm Road, Chapel Hill, NC 27599 7030, USA
    Infect Control Hosp Epidemiol 25:333-41. 2004
  49. pmc Virus transfer from personal protective equipment to healthcare employees' skin and clothing
    Lisa Casanova
    University of North Carolina Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Emerg Infect Dis 14:1291-3. 2008
    ..Following this protocol often resulted in virus transfer to hands and clothing. An altered protocol or other measures are needed to prevent healthcare worker contamination...
  50. ncbi request reprint Effects of long-term storage on sterility of medical supplies
    William A Rutala
    Am J Infect Control 34:248. 2006
  51. ncbi request reprint Recognition and management of anthrax
    David J Weber
    N Engl J Med 346:943-5; author reply 943-5. 2002
  52. ncbi request reprint Cryptosporidiosis
    David J Weber
    N Engl J Med 347:1287. 2002
  53. ncbi request reprint Multi-society guideline for reprocessing flexible gastrointestinal endoscopes
    Douglas B Nelson
    Dis Colon Rectum 47:413-20; discussion 420-1. 2004
  54. ncbi request reprint Multi-society guideline for reprocessing flexible gastrointestinal endoscopes. Society for Healthcare Epidemiology of America
    Douglas B Nelson
    Infect Control Hosp Epidemiol 24:532-7. 2003
    ..The organizations that endorsed this guideline are committed to assisting the FDA and manufacturers in addressing critical infection control issues in gastrointestinal device reprocessing...
  55. ncbi request reprint Multidrug-resistant Enterococcus faecium in a patient with burns
    Sherene S Min
    Clin Infect Dis 36:1210-1. 2003
  56. ncbi request reprint Semipermeable dressing used to cover smallpox vaccination sites as a cause of skin damage
    Elaine Crittenton
    Infect Control Hosp Epidemiol 25:96. 2004