Research Topics
| M T RuffinSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Human papillomavirus vaccine knowledge and hypothetical acceptance among women in Appalachia OhioMack T Ruffin
Department of Family Medicine, University of Michigan, Ann Arbor, MI 48104 1213, United States
Vaccine 30:5349-57. 2012..To assess hypothetical acceptance of the human papillomavirus (HPV) vaccine for themselves and a daughter age 9-12 years among Appalachia Ohio women...
Dose escalation of a curcuminoid formulationChristopher D Lao
Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, 2150 CCGC, Ann Arbor, MI 48109 0930, USA
BMC Complement Altern Med 6:10. 2006..However, few systematic studies of curcumin's pharmacology and toxicology in humans have been performed...
Recruiting subjects in cancer prevention and control studiesM T Ruffin
Department of Family Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0708, USA
J Cell Biochem Suppl 34:80-3. 2000..The authors provide their experience in overcoming these difficulties...- Do antioxidants still have a role in the prevention of human cancer?M T Ruffin
Department of Family Medicine, The University of Michigan Medical School, 1018 Fuller Street, Ann Arbor, MI 48109 0708, USA
Curr Oncol Rep 3:306-13. 2001..The ability of the antioxidant micronutrients to influence the risk for tissue injury and for cancer, mediated by their antioxidant activities, remains hypothetical... - Low-dose topical delivery of all-trans retinoic acid for cervical intraepithelial neoplasia II and IIIMack T Ruffin
Department of Family Medicine, University of Michigan, 1018 Fuller Street, Ann Arbor, MI 48109 0708, USA
Cancer Epidemiol Biomarkers Prev 13:2148-52. 2004..The objective of this study was to determine an effective dose for all-trans retinoic acid (atRA) delivered with a cervical cap and sponge for 4 days to women with cervical intraepithelial neoplasia (CIN) II/III... - Factors influencing choices for colorectal cancer screening among previously unscreened African and Caucasian Americans: findings from a triangulation mixed methods investigationMack T Ruffin
Department of Family Medicine, University of Michigan Health System, Ann Arbor, MI 48104 1213, USA
J Community Health 34:79-89. 2009..New approaches to promoting colorectal cancer screening need to explore methods to facilitate patients establishing and expressing preferences among the screening options... - Interventions fail to increase cancer screening rates in community-based primary care practicesMack T Ruffin
Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109 0708, USA
Prev Med 39:435-40. 2004.... - Preference-based electronic decision aid to promote colorectal cancer screening: results of a randomized controlled trialMack T Ruffin
University of Michigan Health System, Department of Family Medicine, 1018 Fuller Street SPC 5708, Ann Arbor, MI 48109 5708, USA
Prev Med 45:267-73. 2007..We previously developed through a series of studies an interactive electronic tool, Colorectal Web, to promote colorectal cancer screening... - Using patient monetary incentives and electronically derived patient lists to recruit patients to a clinical trialMack T Ruffin
Department of Family Medicine, The University of Michigan, USA
J Am Board Fam Med 24:569-75. 2011..To report using electronic medical record (EMR) data to identify patients eligible for a clinical trial and the impact of providing an honorarium and deadline on accrual... - Family physicians' knowledge of risk factors for cervical cancerMack T Ruffin
Department of Family Medicine, The University of Michigan Health System, Ann Arbor, Michigan, USA
J Womens Health (Larchmt) 12:561-7. 2003..The aim of this study was to determine family physicians' knowledge of risk factors for cervical cancer and perceived importance of risk in screening women... - Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomitingSuzanna M Zick
Departments of Family Medicine, University of Michigan, Ann Arbor, MI, USA
Support Care Cancer 17:563-72. 2009..Ginger has also been studied for its efficacy for acute chemotherapy-induced nausea and vomiting (CINV). However, its efficacy for delayed CINV in a diverse oncology population is unknown... - Impact of a generalizable reminder system on colorectal cancer screening in diverse primary care practices: a report from the prompting and reminding at encounters for prevention projectDonald E Nease
Department of Family Medicine, University of Michigan, Ann Arbor, Michigan 48104 1213, USA
Med Care 46:S68-73. 2008..We evaluated whether a generalizable CRS, ClinfoTracker, could improve screening rates for CRC in diverse primary care practices... - Information technology and cancer preventionMasahito Jimbo
Department of Family Medicine, University of Michigan, Ann Arbor, USA
CA Cancer J Clin 56:26-36; quiz 48-9. 2006..There is critical need to study these new technologic approaches to understand the impact and acceptance by providers and patients... 
Development and evaluation of a PCR and mass spectroscopy (PCR-MS)-based method for quantitative, type-specific detection of human papillomavirusDivya A Patel
Department of Obstetrics and Gynecology, University of Michigan Medical School, Women s Hospital, Ann Arbor, MI 48109 5276, USA
J Virol Methods 160:78-84. 2009..Further validation work is underway to define clinically meaningful HPV detection thresholds and to evaluate the potential clinical application of future generations of the PCR-MS assay...- Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjectsSuzanna M Zick
Deoartment of Family Medicine, University of Michigan Medical School, Ann Arbor, MI 48104, USA
Cancer Epidemiol Biomarkers Prev 17:1930-6. 2008..We conducted a clinical trial with 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol, examining the pharmacokinetics and tolerability of these analytes and their conjugate metabolites... - Developing a Web site in primary careMichael D Fetters
Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109 0708, USA
Fam Med 36:651-9. 2004..This article describes how knowledge gained through focus groups, Web site searches, and individual interviews were used to develop and improve a health-related Web site... - A randomized feasibility trial of brief telephone counseling to increase fruit and vegetable intakesZora Djuric
University of Michigan, Department of Family Medicine, Ann Arbor, MI 48109, USA
Prev Med 50:265-71. 2010..This study examined the feasibility of eliciting dietary changes in subjects recruited from a diverse primary care setting in Michigan using a written, one-page plan, either alone or with telephone counseling... - Recruitment and retention of economically underserved women to a cervical cancer prevention trialJoanne Motino Bailey
School of Nursing, University of Michigan, 1018 Fuller Street, Ann Arbor, MI 48109, USA
Appl Nurs Res 17:55-60. 2004..With these strategies, 90% of eligible patients consented to participate in the study... - Pharmacokinetics of curcumin conjugate metabolites in healthy human subjectsShaiju K Vareed
Department of Internal Medicine, University of Michigan Medical School and Veterans Affairs Medical Center, Ann Arbor, Michigan, USA
Cancer Epidemiol Biomarkers Prev 17:1411-7. 2008..Curcumin is a polyphenol, found in the spice turmeric, that has promising anticancer properties, but previous studies suggest that absorption of curcumin may be limited... - Adults' knowledge and behaviors related to human papillomavirus infectionBryan Holcomb
University of Michigan, Ann Arbor, MI, USA
J Am Board Fam Pract 17:26-31. 2004..The preferred time to receive information about HPV was before a patient became sexually active. However, it remains unclear whether educational intervention or knowledge changes risky behaviors... - Family history and perceptions about risk and prevention for chronic diseases in primary care: a report from the family healthware impact trialLouise S Acheson
Department of Family Medicine, Case Western Reserve University, Cleveland, Ohio, USA
Genet Med 12:212-8. 2010..To determine whether family medical history as a risk factor for six common diseases is related to patients' perceptions of risk, worry, and control over getting these diseases... - Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectin glycoarray and lectin blotYinghua Qiu
Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA
J Proteome Res 7:1693-703. 2008..These results demonstrate the utility of this strategy for the identification of N -linked glycan patterns as potential markers of CRC in human plasma, and may have the utility to distinguish different disease states... - Women's feedback on a chemopreventive trial for cervical dysplasiaMary E Bieniasz
Department of Family Medicine, University of Michigan, 1018 Fuller Street, Ann Arbor, MI 48109-0708, USA
Appl Nurs Res 16:22-8. 2003..However, in this study, women (63% black, 26% white, and 9% other ethnicity), were interested in participating and reported only moderate barriers. These barriers could easily be addressed with resources available to investigators... - Chaperone use by family physicians during the collection of a Pap smearPamela Rockwell
Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109-0708, USA
Ann Fam Med 1:218-20. 2003..The variation could reflect different regional or local norms, efficiency or resource issues in high-volume clinical settings, or other interpersonal factors. These issues need to be explored in more depth... - Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancerWendy Demark-Wahnefried
Division of Cancer Prevention and Control Department of Behavioral Science, MD Anderson Cancer Center, Houston, TX, USA
Clin Trials 5:262-72. 2008..Despite the many strengths of presurgical models, there are practical issues and challenges that arise when using this approach... - Gene expression profile of cervical tissue compared to exfoliated cells: impact on biomarker discoveryMartin Steinau
Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Genomics 6:64. 2005..However, because of keratinization and terminal differentiation it is not clear that these cells have an mRNA profile representative of cervical tissue, and that the profile can distinguish the lesions targeted for early detection... - Epidemiologic and viral factors associated with cervical neoplasia in HPV-16-positive womenMangalathu S Rajeevan
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Int J Cancer 115:114-20. 2005..Cellular proliferation and differentiation pathways affected by HPV should be investigated as biomarkers for cervical cancer screening... - Effects of low dose aspirin (81 mg) on proliferating cell nuclear antigen and Amaranthus caudatus labeling in normal-risk and high-risk human subjects for colorectal cancerKoyamangalath Krishnan
Medical Service, James H. Quillen Veterans Administration Medical Center and Division of Hematology-Oncology, Department of Internal Medicine, East Tennessee State University, Johnson City, TN 37614, USA
Cancer Detect Prev 28:107-13. 2004..PCNA and ACA LIs are not useful as proliferation biomarkers for aspirin's chemopreventive activity in morphologically normal human colorectal mucosa... - Evaluation of RNA markers for early detection of cervical neoplasia in exfoliated cervical cellsMartin Steinau
Division of Viral and Rickettsial Disease, Viral Exanthems and Herpesvirus Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 41, Atlanta, GA 30333, USA
Cancer Epidemiol Biomarkers Prev 16:295-301. 2007....
Research Grants
- Cancer Chemoprevention and Mentoring Clinical ResearchersMack Ruffin; Fiscal Year: 2007..However, the group is in a critical phase of development. The continued support of Dr. Ruffin with an additional five years of support will be vital to reaching the goal. ..