M T Ruffin

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Human papillomavirus vaccine knowledge and hypothetical acceptance among women in Appalachia Ohio
    Mack T Ruffin
    Department of Family Medicine, University of Michigan, Ann Arbor, MI 48104 1213, United States
    Vaccine 30:5349-57. 2012
  2. pmc Dose escalation of a curcuminoid formulation
    Christopher D Lao
    Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, 2150 CCGC, Ann Arbor, MI 48109 0930, USA
    BMC Complement Altern Med 6:10. 2006
  3. ncbi request reprint Do antioxidants still have a role in the prevention of human cancer?
    M T Ruffin
    Department of Family Medicine, The University of Michigan Medical School, 1018 Fuller Street, Ann Arbor, MI 48109 0708, USA
    Curr Oncol Rep 3:306-13. 2001
  4. ncbi request reprint Low-dose topical delivery of all-trans retinoic acid for cervical intraepithelial neoplasia II and III
    Mack T Ruffin
    Department of Family Medicine, University of Michigan, 1018 Fuller Street, Ann Arbor, MI 48109 0708, USA
    Cancer Epidemiol Biomarkers Prev 13:2148-52. 2004
  5. doi request reprint Factors influencing choices for colorectal cancer screening among previously unscreened African and Caucasian Americans: findings from a triangulation mixed methods investigation
    Mack T Ruffin
    Department of Family Medicine, University of Michigan Health System, Ann Arbor, MI 48104 1213, USA
    J Community Health 34:79-89. 2009
  6. ncbi request reprint Interventions fail to increase cancer screening rates in community-based primary care practices
    Mack T Ruffin
    Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109 0708, USA
    Prev Med 39:435-40. 2004
  7. ncbi request reprint Preference-based electronic decision aid to promote colorectal cancer screening: results of a randomized controlled trial
    Mack T Ruffin
    University of Michigan Health System, Department of Family Medicine, 1018 Fuller Street SPC 5708, Ann Arbor, MI 48109 5708, USA
    Prev Med 45:267-73. 2007
  8. doi request reprint Using patient monetary incentives and electronically derived patient lists to recruit patients to a clinical trial
    Mack T Ruffin
    Department of Family Medicine, The University of Michigan, USA
    J Am Board Fam Med 24:569-75. 2011
  9. ncbi request reprint Family physicians' knowledge of risk factors for cervical cancer
    Mack T Ruffin
    Department of Family Medicine, The University of Michigan Health System, Ann Arbor, Michigan, USA
    J Womens Health (Larchmt) 12:561-7. 2003
  10. ncbi request reprint Recruiting subjects in cancer prevention and control studies
    M T Ruffin
    Department of Family Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0708, USA
    J Cell Biochem Suppl 34:80-3. 2000

Research Grants

Collaborators

Detail Information

Publications30

  1. pmc Human papillomavirus vaccine knowledge and hypothetical acceptance among women in Appalachia Ohio
    Mack T Ruffin
    Department of Family Medicine, University of Michigan, Ann Arbor, MI 48104 1213, United States
    Vaccine 30:5349-57. 2012
    ..To assess hypothetical acceptance of the human papillomavirus (HPV) vaccine for themselves and a daughter age 9-12 years among Appalachia Ohio women...
  2. pmc Dose escalation of a curcuminoid formulation
    Christopher D Lao
    Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, 2150 CCGC, Ann Arbor, MI 48109 0930, USA
    BMC Complement Altern Med 6:10. 2006
    ..However, few systematic studies of curcumin's pharmacology and toxicology in humans have been performed...
  3. ncbi request reprint Do antioxidants still have a role in the prevention of human cancer?
    M T Ruffin
    Department of Family Medicine, The University of Michigan Medical School, 1018 Fuller Street, Ann Arbor, MI 48109 0708, USA
    Curr Oncol Rep 3:306-13. 2001
    ..The ability of the antioxidant micronutrients to influence the risk for tissue injury and for cancer, mediated by their antioxidant activities, remains hypothetical...
  4. ncbi request reprint Low-dose topical delivery of all-trans retinoic acid for cervical intraepithelial neoplasia II and III
    Mack T Ruffin
    Department of Family Medicine, University of Michigan, 1018 Fuller Street, Ann Arbor, MI 48109 0708, USA
    Cancer Epidemiol Biomarkers Prev 13:2148-52. 2004
    ..The objective of this study was to determine an effective dose for all-trans retinoic acid (atRA) delivered with a cervical cap and sponge for 4 days to women with cervical intraepithelial neoplasia (CIN) II/III...
  5. doi request reprint Factors influencing choices for colorectal cancer screening among previously unscreened African and Caucasian Americans: findings from a triangulation mixed methods investigation
    Mack T Ruffin
    Department of Family Medicine, University of Michigan Health System, Ann Arbor, MI 48104 1213, USA
    J Community Health 34:79-89. 2009
    ..New approaches to promoting colorectal cancer screening need to explore methods to facilitate patients establishing and expressing preferences among the screening options...
  6. ncbi request reprint Interventions fail to increase cancer screening rates in community-based primary care practices
    Mack T Ruffin
    Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109 0708, USA
    Prev Med 39:435-40. 2004
    ....
  7. ncbi request reprint Preference-based electronic decision aid to promote colorectal cancer screening: results of a randomized controlled trial
    Mack T Ruffin
    University of Michigan Health System, Department of Family Medicine, 1018 Fuller Street SPC 5708, Ann Arbor, MI 48109 5708, USA
    Prev Med 45:267-73. 2007
    ..We previously developed through a series of studies an interactive electronic tool, Colorectal Web, to promote colorectal cancer screening...
  8. doi request reprint Using patient monetary incentives and electronically derived patient lists to recruit patients to a clinical trial
    Mack T Ruffin
    Department of Family Medicine, The University of Michigan, USA
    J Am Board Fam Med 24:569-75. 2011
    ..To report using electronic medical record (EMR) data to identify patients eligible for a clinical trial and the impact of providing an honorarium and deadline on accrual...
  9. ncbi request reprint Family physicians' knowledge of risk factors for cervical cancer
    Mack T Ruffin
    Department of Family Medicine, The University of Michigan Health System, Ann Arbor, Michigan, USA
    J Womens Health (Larchmt) 12:561-7. 2003
    ..The aim of this study was to determine family physicians' knowledge of risk factors for cervical cancer and perceived importance of risk in screening women...
  10. ncbi request reprint Recruiting subjects in cancer prevention and control studies
    M T Ruffin
    Department of Family Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0708, USA
    J Cell Biochem Suppl 34:80-3. 2000
    ..The authors provide their experience in overcoming these difficulties...
  11. doi request reprint Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting
    Suzanna M Zick
    Departments of Family Medicine, University of Michigan, Ann Arbor, MI, USA
    Support Care Cancer 17:563-72. 2009
    ..Ginger has also been studied for its efficacy for acute chemotherapy-induced nausea and vomiting (CINV). However, its efficacy for delayed CINV in a diverse oncology population is unknown...
  12. doi request reprint Impact of a generalizable reminder system on colorectal cancer screening in diverse primary care practices: a report from the prompting and reminding at encounters for prevention project
    Donald E Nease
    Department of Family Medicine, University of Michigan, Ann Arbor, Michigan 48104 1213, USA
    Med Care 46:S68-73. 2008
    ..We evaluated whether a generalizable CRS, ClinfoTracker, could improve screening rates for CRC in diverse primary care practices...
  13. ncbi request reprint Information technology and cancer prevention
    Masahito Jimbo
    Department of Family Medicine, University of Michigan, Ann Arbor, USA
    CA Cancer J Clin 56:26-36; quiz 48-9. 2006
    ..There is critical need to study these new technologic approaches to understand the impact and acceptance by providers and patients...
  14. pmc Development and evaluation of a PCR and mass spectroscopy (PCR-MS)-based method for quantitative, type-specific detection of human papillomavirus
    Divya A Patel
    Department of Obstetrics and Gynecology, University of Michigan Medical School, Women s Hospital, Ann Arbor, MI 48109 5276, USA
    J Virol Methods 160:78-84. 2009
    ..Further validation work is underway to define clinically meaningful HPV detection thresholds and to evaluate the potential clinical application of future generations of the PCR-MS assay...
  15. ncbi request reprint Developing a Web site in primary care
    Michael D Fetters
    Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109 0708, USA
    Fam Med 36:651-9. 2004
    ..This article describes how knowledge gained through focus groups, Web site searches, and individual interviews were used to develop and improve a health-related Web site...
  16. pmc A randomized feasibility trial of brief telephone counseling to increase fruit and vegetable intakes
    Zora Djuric
    University of Michigan, Department of Family Medicine, Ann Arbor, MI 48109, USA
    Prev Med 50:265-71. 2010
    ..This study examined the feasibility of eliciting dietary changes in subjects recruited from a diverse primary care setting in Michigan using a written, one-page plan, either alone or with telephone counseling...
  17. pmc Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjects
    Suzanna M Zick
    Deoartment of Family Medicine, University of Michigan Medical School, Ann Arbor, MI 48104, USA
    Cancer Epidemiol Biomarkers Prev 17:1930-6. 2008
    ..We conducted a clinical trial with 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol, examining the pharmacokinetics and tolerability of these analytes and their conjugate metabolites...
  18. ncbi request reprint Recruitment and retention of economically underserved women to a cervical cancer prevention trial
    Joanne Motino Bailey
    School of Nursing, University of Michigan, 1018 Fuller Street, Ann Arbor, MI 48109, USA
    Appl Nurs Res 17:55-60. 2004
    ..With these strategies, 90% of eligible patients consented to participate in the study...
  19. doi request reprint Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects
    Shaiju K Vareed
    Department of Internal Medicine, University of Michigan Medical School and Veterans Affairs Medical Center, Ann Arbor, Michigan, USA
    Cancer Epidemiol Biomarkers Prev 17:1411-7. 2008
    ..Curcumin is a polyphenol, found in the spice turmeric, that has promising anticancer properties, but previous studies suggest that absorption of curcumin may be limited...
  20. doi request reprint Family history and perceptions about risk and prevention for chronic diseases in primary care: a report from the family healthware impact trial
    Louise S Acheson
    Department of Family Medicine, Case Western Reserve University, Cleveland, Ohio, USA
    Genet Med 12:212-8. 2010
    ..To determine whether family medical history as a risk factor for six common diseases is related to patients' perceptions of risk, worry, and control over getting these diseases...
  21. ncbi request reprint Adults' knowledge and behaviors related to human papillomavirus infection
    Bryan Holcomb
    University of Michigan, Ann Arbor, MI, USA
    J Am Board Fam Pract 17:26-31. 2004
    ..Our objective was to assess adults' knowledge, risk behaviors, and preference for information about human papillomavirus (HPV)...
  22. pmc Plasma glycoprotein profiling for colorectal cancer biomarker identification by lectin glycoarray and lectin blot
    Yinghua Qiu
    Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Proteome Res 7:1693-703. 2008
    ..These results demonstrate the utility of this strategy for the identification of N -linked glycan patterns as potential markers of CRC in human plasma, and may have the utility to distinguish different disease states...
  23. ncbi request reprint Women's feedback on a chemopreventive trial for cervical dysplasia
    Mary E Bieniasz
    Department of Family Medicine, University of Michigan, 1018 Fuller Street, Ann Arbor, MI 48109 0708, USA
    Appl Nurs Res 16:22-8. 2003
    ..However, in this study, women (63% black, 26% white, and 9% other ethnicity), were interested in participating and reported only moderate barriers. These barriers could easily be addressed with resources available to investigators...
  24. pmc Chaperone use by family physicians during the collection of a Pap smear
    Pamela Rockwell
    Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109 0708, USA
    Ann Fam Med 1:218-20. 2003
    ..We wanted to determine whether variations exist in use of a chaperone during the performance of a pelvic examination by family physicians...
  25. pmc Overcoming challenges in designing and implementing a phase II randomized controlled trial using a presurgical model to test a dietary intervention in prostate cancer
    Wendy Demark-Wahnefried
    Division of Cancer Prevention and Control Department of Behavioral Science, MD Anderson Cancer Center, Houston, TX, USA
    Clin Trials 5:262-72. 2008
    ..Despite the many strengths of presurgical models, there are practical issues and challenges that arise when using this approach...
  26. pmc Gene expression profile of cervical tissue compared to exfoliated cells: impact on biomarker discovery
    Martin Steinau
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Genomics 6:64. 2005
    ..However, because of keratinization and terminal differentiation it is not clear that these cells have an mRNA profile representative of cervical tissue, and that the profile can distinguish the lesions targeted for early detection...
  27. ncbi request reprint Epidemiologic and viral factors associated with cervical neoplasia in HPV-16-positive women
    Mangalathu S Rajeevan
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Int J Cancer 115:114-20. 2005
    ..Cellular proliferation and differentiation pathways affected by HPV should be investigated as biomarkers for cervical cancer screening...
  28. ncbi request reprint Effects of low dose aspirin (81 mg) on proliferating cell nuclear antigen and Amaranthus caudatus labeling in normal-risk and high-risk human subjects for colorectal cancer
    Koyamangalath Krishnan
    Medical Service, James H Quillen Veterans Administration Medical Center and Division of Hematology Oncology, Department of Internal Medicine, East Tennessee State University, Johnson City, TN 37614, USA
    Cancer Detect Prev 28:107-13. 2004
    ..PCNA and ACA LIs are not useful as proliferation biomarkers for aspirin's chemopreventive activity in morphologically normal human colorectal mucosa...
  29. ncbi request reprint Evaluation of RNA markers for early detection of cervical neoplasia in exfoliated cervical cells
    Martin Steinau
    Division of Viral and Rickettsial Disease, Viral Exanthems and Herpesvirus Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 41, Atlanta, GA 30333, USA
    Cancer Epidemiol Biomarkers Prev 16:295-301. 2007
    ....

Research Grants2

  1. Cancer Chemoprevention and Mentoring Clinical Researchers
    Mack Ruffin; Fiscal Year: 2007
    ..However, the group is in a critical phase of development. The continued support of Dr. Ruffin with an additional five years of support will be vital to reaching the goal. ..