C M Rudin

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. ncbi Phase I Trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer
    C M Rudin
    Section of Hematology Oncology, University of Chicago Medical Center, Chicago, Illinois 60637 1470, USA
    Clin Cancer Res 7:1214-20. 2001
  2. ncbi A phase II study of oxaliplatin and paclitaxel in patients with advanced non-small-cell lung cancer
    J D Winegarden
    University of Chicago Section of Hematology/Oncology and University of Chicago Cancer Research Center, Chicago, IL 60637, USA
    Ann Oncol 15:915-20. 2004
  3. ncbi ONYX-015. Onyx Pharmaceuticals
    E E Cohen
    Section of Hematology Oncology, University of Chicago Medical Center, IL 60637, USA
    Curr Opin Investig Drugs 2:1770-5. 2001
  4. ncbi A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer
    C M Rudin
    Section of Hematology Oncology, University of Chicago Medical Center, IL 60637 1470, USA
    Ann Oncol 13:539-45. 2002
  5. ncbi A Bcl-xL transgene promotes malignant conversion of chemically initiated skin papillomas
    J C Pena
    Gwen Knapp Center for Lupus and Immunology Research, Committee on Immunology, University of Chicago, Illinois 60637, USA
    Cancer Res 58:2111-6. 1998
  6. ncbi A phase I trial of the oral platinum analogue JM216 with concomitant radiotherapy in advanced malignancies of the chest
    C M George
    Section of Hematology/Oncology, University of Chicago, IL, USA
    Invest New Drugs 19:303-10. 2001

Detail Information

Publications6

  1. ncbi Phase I Trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer
    C M Rudin
    Section of Hematology Oncology, University of Chicago Medical Center, Chicago, Illinois 60637 1470, USA
    Clin Cancer Res 7:1214-20. 2001
    ....
  2. ncbi A phase II study of oxaliplatin and paclitaxel in patients with advanced non-small-cell lung cancer
    J D Winegarden
    University of Chicago Section of Hematology/Oncology and University of Chicago Cancer Research Center, Chicago, IL 60637, USA
    Ann Oncol 15:915-20. 2004
    ..No grade 4 non-hematological toxicities were encountered. CONCLUSION: This regimen is well tolerated, and demonstrates activity in patients with advanced NSCLC...
  3. ncbi ONYX-015. Onyx Pharmaceuticals
    E E Cohen
    Section of Hematology Oncology, University of Chicago Medical Center, IL 60637, USA
    Curr Opin Investig Drugs 2:1770-5. 2001
    ..In April 1999, the company also received EP-094910177.8 covering the technology in Europe...
  4. ncbi A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer
    C M Rudin
    Section of Hematology Oncology, University of Chicago Medical Center, IL 60637 1470, USA
    Ann Oncol 13:539-45. 2002
    ..Suppression of Bcl-2 levels through the use of G3139, an antisense oligonucleotide complementary to the mRNA encoding Bcl-2, might increase the antitumor efficacy of cytotoxic therapy...
  5. ncbi A Bcl-xL transgene promotes malignant conversion of chemically initiated skin papillomas
    J C Pena
    Gwen Knapp Center for Lupus and Immunology Research, Committee on Immunology, University of Chicago, Illinois 60637, USA
    Cancer Res 58:2111-6. 1998
    ..In contrast, Bcl-xL overexpression can dramatically increase the malignant conversion rate of benign tumors, suggesting that inhibition of apoptosis can contribute to tumor progression...
  6. ncbi A phase I trial of the oral platinum analogue JM216 with concomitant radiotherapy in advanced malignancies of the chest
    C M George
    Section of Hematology/Oncology, University of Chicago, IL, USA
    Invest New Drugs 19:303-10. 2001
    ..The major DLT is myelosuppression with only limited increased toxicity within the field of radiation. This conceivably may limit the use of JM216 as a radiation sensitizer...