J B Rubins

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi request reprint Pneumococcal disease in the elderly: what is preventing vaccine efficacy?
    J B Rubins
    Pulmonary Diseases, Veterans Affairs Medical Center and Department of Medicine, University of Minnesota School of Medicine, Minneapolis 55417, USA
    Drugs Aging 18:305-11. 2001
  2. ncbi request reprint Community-acquired pneumonia. Tailoring management of adult patients according to risk category
    J B Rubins
    Pulmonary Disease Section, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
    Postgrad Med 102:45-7, 52, 55-62. 1997
  3. ncbi request reprint Lovastatin induces apoptosis in malignant mesothelioma cells
    J B Rubins
    Department of Medicine, Veterans Affairs Medical Center, University of Minnesota, Minneapolis, USA
    Am J Respir Crit Care Med 157:1616-22. 1998
  4. ncbi request reprint Magnitude, duration, quality, and function of pneumococcal vaccine responses in elderly adults
    J B Rubins
    Pulmonary Section, Department of Medicine, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
    J Infect Dis 178:431-40. 1998
  5. ncbi request reprint Diagnosis of venous thromboembolism. Step-by-step approach to a still lethal disease
    J B Rubins
    Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
    Postgrad Med 108:175-80; quiz 16. 2000
  6. ncbi request reprint Identification of clinical risk factors for nosocomial pneumococcal bacteremia
    J B Rubins
    Department of Pulmonary Disease, and Center for Chronic Diseases Outcome Research, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    Clin Infect Dis 29:178-83. 1999
  7. ncbi request reprint Temporal trends in survival after surgical resection of localized non-small cell lung cancer
    J B Rubins
    Pulmonary Division 111N, Department of Medicine, Minneapolis Veterans Affairs Medical Center, University of Minnesota, 1 Veterans Drive, Minneapolis, MN 55417, USA
    Lung Cancer 28:21-7. 2000
  8. pmc Determination of antibody responses of elderly adults to all 23 capsular polysaccharides after pneumococcal vaccination
    J B Rubins
    Pulmonary Diseases, Veterans Affairs Medical Center, University of Minnesota School of Medicine, Minneapolis, Minnesota 55417, USA
    Infect Immun 67:5979-84. 1999
  9. pmc Killing of Streptococcus pneumoniae by capsular polysaccharide-specific polymeric IgA, complement, and phagocytes
    E N Janoff
    Infectious Disease Section, Department of Medicine, Veterans Affairs Medical Center and University of Minnesota Medical School, Minneapolis, Minnesota 55417, USA
    J Clin Invest 104:1139-47. 1999
  10. ncbi request reprint Inhibition of mesothelioma cell growth in vitro by doxycycline
    J B Rubins
    Pulmonary Diseases and Oncology, Department of Medicine, Veterans Affairs Medical Center, Minneapolis, Minnesota, USA
    J Lab Clin Med 138:101-6. 2001

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Pneumococcal disease in the elderly: what is preventing vaccine efficacy?
    J B Rubins
    Pulmonary Diseases, Veterans Affairs Medical Center and Department of Medicine, University of Minnesota School of Medicine, Minneapolis 55417, USA
    Drugs Aging 18:305-11. 2001
    ....
  2. ncbi request reprint Community-acquired pneumonia. Tailoring management of adult patients according to risk category
    J B Rubins
    Pulmonary Disease Section, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
    Postgrad Med 102:45-7, 52, 55-62. 1997
    ..Failure of the patient to respond to empirical antibiotic therapy within 72 hours should direct the clinician to consider unusual or resistant organisms or noninfectious causes of pneumonitis...
  3. ncbi request reprint Lovastatin induces apoptosis in malignant mesothelioma cells
    J B Rubins
    Department of Medicine, Veterans Affairs Medical Center, University of Minnesota, Minneapolis, USA
    Am J Respir Crit Care Med 157:1616-22. 1998
    ..Thus, lovastatin is a commercially available and clinically well-tolerated agent that reduces viability and induces apoptosis of mesothelioma cells, and may provide the basis for adjunctive treatments of patients with mesothelioma...
  4. ncbi request reprint Magnitude, duration, quality, and function of pneumococcal vaccine responses in elderly adults
    J B Rubins
    Pulmonary Section, Department of Medicine, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
    J Infect Dis 178:431-40. 1998
    ..Thus, despite the adequate mean immune responses of the elderly as a group, a substantial proportion of elderly persons may have poor responses to the currently available pneumococcal vaccine...
  5. ncbi request reprint Diagnosis of venous thromboembolism. Step-by-step approach to a still lethal disease
    J B Rubins
    Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
    Postgrad Med 108:175-80; quiz 16. 2000
    ..The algorithm presented in this article facilitates the practical and efficient use of available resources in diagnosing and treating VTE...
  6. ncbi request reprint Identification of clinical risk factors for nosocomial pneumococcal bacteremia
    J B Rubins
    Department of Pulmonary Disease, and Center for Chronic Diseases Outcome Research, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    Clin Infect Dis 29:178-83. 1999
    ..5%, compared with 1.2% among nonbacteremic controls (P < .00001). We conclude that NPB is a highly lethal infection that is associated with distinct but identifiable clinical risks, symptoms, and signs...
  7. ncbi request reprint Temporal trends in survival after surgical resection of localized non-small cell lung cancer
    J B Rubins
    Pulmonary Division 111N, Department of Medicine, Minneapolis Veterans Affairs Medical Center, University of Minnesota, 1 Veterans Drive, Minneapolis, MN 55417, USA
    Lung Cancer 28:21-7. 2000
    ..We conclude that perioperative mortality after resection of localized NSCLC improved, but subsequent postoperative survival for these patients did not significantly improve over the 45-year period studied...
  8. pmc Determination of antibody responses of elderly adults to all 23 capsular polysaccharides after pneumococcal vaccination
    J B Rubins
    Pulmonary Diseases, Veterans Affairs Medical Center, University of Minnesota School of Medicine, Minneapolis, Minnesota 55417, USA
    Infect Immun 67:5979-84. 1999
    ..However, no particular group of vaccine polysaccharides could be used as a marker for adequate immune responses if only postvaccination sera were analyzed...
  9. pmc Killing of Streptococcus pneumoniae by capsular polysaccharide-specific polymeric IgA, complement, and phagocytes
    E N Janoff
    Infectious Disease Section, Department of Medicine, Veterans Affairs Medical Center and University of Minnesota Medical School, Minneapolis, Minnesota 55417, USA
    J Clin Invest 104:1139-47. 1999
    ..pneumoniae in the presence or absence of inflammation. These data suggest mechanisms whereby pIgA may serve to control pneumococcal infections locally and upon the pathogen's entry into the bloodstream...
  10. ncbi request reprint Inhibition of mesothelioma cell growth in vitro by doxycycline
    J B Rubins
    Pulmonary Diseases and Oncology, Department of Medicine, Veterans Affairs Medical Center, Minneapolis, Minnesota, USA
    J Lab Clin Med 138:101-6. 2001
    ..Thus doxycycline may have a role as adjuvant therapy for malignant mesothelioma...
  11. ncbi request reprint Immune activation and virologic response to immunization in recent HIV type 1 seroconverters
    E N Janoff
    Department of Medicine, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    AIDS Res Hum Retroviruses 15:837-45. 1999
    ..Thus, respiratory bacterial vaccines appear immunogenic and safe early in HIV-1 infection...
  12. ncbi request reprint Effect of anesthetics on pathogenesis of experimentally induced murine pneumococcal pneumonia
    J B Rubins
    Veterans Affairs Medical Center, and Department of Medicine, University of Minnesota School of Medicine, Minneapolis, USA
    Comp Med 50:292-5. 2000
    ....
  13. ncbi request reprint Mechanisms of G1 checkpoint loss in resected early stage non-small cell lung cancer
    J X Zhou
    Department of Research Service, Minneapolis Veterans Affairs Medical Center, University of Minnesota Medical School, Minneapolis, MN 55417, USA
    Lung Cancer 32:27-38. 2001
    ..Although loss of p16INK4a function remains tightly correlated with pRB expression, loss of other regulatory elements in NSCLC such as p53 mutation and cyclin D1 over-expression appear independent of loss of the p16INK4a gene product...
  14. pmc Role of gamma interferon in the pathogenesis of bacteremic pneumococcal pneumonia
    J B Rubins
    Veterans Affairs Medical Center, and Department of Medicine, University of Minnesota, Minneapolis 55417, USA
    Infect Immun 65:2975-7. 1997
    ..Compared with that of immunocompetent mice, mortality was appreciably increased after pulmonary infection of IFN-gamma gene knockout mice, suggesting a protective role for IFN-gamma in host response to pneumococcal disease...
  15. pmc Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia
    J B Rubins
    Pulmonary Disease Division, Veterans Affairs Medical Center, Minneapolis, Minnesota
    J Clin Invest 95:142-50. 1995
    ..Moreover, both the cytotoxic and the complement-activating activities of pneumolysin may contribute independently to the acute pulmonary injury and the high rates of bacteremia which characterize pneumococcal pneumonia...