Research Topics
Species | David R RubinowSummaryAffiliation: University of North Carolina Country: USA Publications
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Detail Information
Publications
Facial emotion discrimination across the menstrual cycle in women with premenstrual dysphoric disorder (PMDD) and controlsDavid R Rubinow
Behavioral Endocrinology Branch, National Institute of Mental Health, Bethesda MD 20892 1276, United States
J Affect Disord 104:37-44. 2007..e., state dependent)...
Monoamines and neurosteroids in sexual function during induced hypogonadism in healthy menMiki Bloch
Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
Arch Gen Psychiatry 63:450-6. 2006..CONCLUSION: These data suggest that the neurosteroid androsterone contributes to the regulation of sexual function in men...
Pharmacologically induced hypogonadism and sexual function in healthy young women and menPeter J Schmidt
Behavioral Endocrinology Branch, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20892 1276, USA
Neuropsychopharmacology 34:565-76. 2009....
Dehydroepiandrosterone monotherapy in midlife-onset major and minor depressionPeter J Schmidt
Behavioral Endocrinology Branch, National Institute of Mental Health, Rockville, MD 20892 1276, USA
Arch Gen Psychiatry 62:154-62. 2005..The adrenal androgen and neurosteroid dehydroepiandrosterone (DHEA) is available as over-the-counter hormonal therapy and previously has been reported to have antidepressant-like effects...
Rapid response to fluoxetine in women with premenstrual dysphoric disorderEmma M Steinberg
Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Depress Anxiety 29:531-40. 2012..Selective serotonin reuptake inhibitors (SRIs) relieve irritability within days in women with premenstrual dysphoric disorder (PMDD); however, the effects on other affective symptoms in PMDD remain to be demonstrated...
Depression in women with spontaneous 46, XX primary ovarian insufficiencyPeter J Schmidt
Behavioral Endocrinology Branch, National Institute of Mental Health, 10 Center Drive MSC 1277, Bethesda, Maryland 20892 1277, USA
J Clin Endocrinol Metab 96:E278-87. 2011..Indeed, studies suggest that depression and/or its pharmacological treatment contribute to the onset of POI...
A cross-sectional evaluation of perimenopausal depressionEmma M Steinberg
Behavioral Endocrinology Branch, National Institute of Mental Health, Bethesda, MD 20892 1276, USA
J Clin Psychiatry 69:973-80. 2008....
Testosterone suppression of CRH-stimulated cortisol in menDavid R Rubinow
Behavioral Endocrinology Branch, National Institute of Mental Health, Building 10 CRC, 10 Center Drive MSC 1276, Bethesda, MD 20892 1276, USA
Neuropsychopharmacology 30:1906-12. 2005..Our results further demonstrate that the enhanced stimulated HPA axis activity previously described in young men compared with young women cannot be ascribed to an activational upregulation of the axis by testosterone...
Concordant restoration of ovarian function and mood in perimenopausal depressionRobert C Daly
Behavioral Endocrinology Branch, National Institute of Mental Health, Bethesda, MD 20892-1276, USA
Am J Psychiatry 160:1842-6. 2003..2 IU/liter [SD=36.6] and 51.5 IU/liter [SD=34.2]). CONCLUSIONS: Mood variability in women with perimenopausal depression may reflect episodic alterations in ovarian function that are best detected by longitudinal study designs...
Sex hormones and mood in the perimenopausePeter J Schmidt
Behavioral Endocrinology Branch, National Institute of Mental Health, Department of Health and Human Services, Bethesda, Maryland, USA
Ann N Y Acad Sci 1179:70-85. 2009..Thus, although depression is not a uniform accompaniment of the menopause transition, in some women, age-related changes in ovarian estrogen production may alter central nervous system function and predispose them to develop depression...
Reproductive ageing, sex steroids and depressionPeter J Schmidt
Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1276, USA
J Br Menopause Soc 12:178-85. 2006..Future studies of perimenopausal depression should identify the number of women affected, individual risk factors and the role of hormonal therapies in this condition...
Magnesium (mg) retention and mood effects after intravenous mg infusion in premenstrual dysphoric disorderKhursheed Khine
Behavioral Endocrinology Branch, National Institute of Mental Health, National Institute of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1277, USA
Biol Psychiatry 59:327-33. 2006..Conflicting data exist regarding the presence of magnesium (Mg) deficiency and the therapeutic efficacy of Mg in premenstrual syndrome or premenstrual dysphoric disorder (PMDD)...
Operationalizing DSM-IV criteria for PMDD: selecting symptomatic and asymptomatic cycles for researchMark J Smith
Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bldg. 10, Room 3N238, 10 Center Dr MSC 1276, Bethesda MD 20892-1276, USA
J Psychiatr Res 37:75-83. 2003..At the very least, the method for operationalizing DSM-IV criteria should be described in studies of PMDD...
Risk for premenstrual dysphoric disorder is associated with genetic variation in ESR1, the estrogen receptor alpha geneLiang Huo
Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
Biol Psychiatry 62:925-33. 2007..Premenstrual dysphoric disorder (PMDD) is a heritable mood disorder that is triggered by gonadal steroids during the luteal phase in susceptible women...
Gonadal steroid regulation of mood: the lessons of premenstrual syndromeDavid R Rubinow
Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 1276, USA
Front Neuroendocrinol 27:210-6. 2006....
Current and lifetime psychiatric illness in women with Turner syndromeGraca Cardoso
Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892-1276, USA
Gynecol Endocrinol 19:313-9. 2004..Women with TS reported a higher rate of lifetime depression compared with rates observed in community-based studies but similar to those obtained from gynecologic clinic samples...
Feasibility and diagnostic validity of the M-3 checklist: a brief, self-rated screen for depressive, bipolar, anxiety, and post-traumatic stress disorders in primary careBradley N Gaynes
Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 7160, USA
Ann Fam Med 8:160-9. 2010..We wanted to assess the feasibility and diagnostic validity of the My Mood Monitor (M-3) checklist, a new, 1-page, patient-rated, 27-item tool developed to screen for multiple psychiatric disorders in primary care...
Why study reproductive neuroscience? A clinical perspectivePeter J Schmidt
Behavioral Endocrinology Branch, National Institute of Mental Health, Bethesda, Maryland, USA
J Clin Psychiatry 69:972. 2008
The effects of pharmacologically induced hypogonadism on mood in healthy menPeter J Schmidt
Behavioral Endocrinology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1276, USA
Arch Gen Psychiatry 61:997-1004. 2004..The effects of declining androgen secretion on mood regulation and the potential psychotropic efficacy of androgen replacement in men are largely undetermined...
The menopause transition: the next neuroendocrine frontierVeronica Harsh
National Institutes of Health, Behavioral Endocrinology Branch, National Institute of Mental Health, Department of Health and Human Services, Bldg 10-CRC, Room 65340, 10 Center Drive MSC 1276, Bethesda, MD 20892-1276, USA
Expert Rev Neurother 7:S7-10. 2007
Differentiation of women with premenstrual dysphoric disorder, recurrent brief depression, and healthy controls by daily mood rating dynamicsSteven M Pincus
J Psychiatr Res 42:337-47. 2008..The statistical methodologies have broad and direct applicability to behavioral studies for many psychiatric disorders, and indeed to similar analyses of associated biological signals across multiple axes...
Differential menstrual cycle regulation of hypothalamic-pituitary-adrenal axis in women with premenstrual syndrome and controlsCatherine A Roca
Behavioral Endocrinology, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
J Clin Endocrinol Metab 88:3057-63. 2003..These data demonstrate that women with PMS, when symptomatic, appear to have an abnormal response to progesterone and, furthermore, do not display the HPA axis abnormalities characteristic of major depression...
Effects of metergoline on symptoms in women with premenstrual dysphoric disorderCatherine A Roca
National Institute of Mental Health, Bethesda, MD 20892 1277, USA
Am J Psychiatry 159:1876-81. 2002..The authors investigated the role of acute serotonergic modulation in the efficacy of selective serotonin reuptake inhibitors (SSRIs) in women with premenstrual dysphoric disorder...
Abnormal luteal phase excitability of the motor cortex in women with premenstrual syndromeMark J Smith
National Institute of Neurological Disorders and Stroke, NIH, Bethesda, Maryland 20892, USA
Biol Psychiatry 54:757-62. 2003..Control subjects showed more inhibition in the luteal phase. Women with PMS showed relative facilitation. CONCLUSIONS: This is the first physiological evidence for an abnormal brain response to progesterone in PMS...
A longitudinal evaluation of the relationship between reproductive status and mood in perimenopausal womenPeter J Schmidt
Behavioral Endocrinology Branch, NIMH, NIH, Department of Health and Human Services, Rm 3N238, Bldg 10, 10 Center Dr, MSC 1276, Bethesda, MD 20892 1276, USA
Am J Psychiatry 161:2238-44. 2004..Mood and reproductive function were prospectively evaluated in asymptomatic premenopausal women to determine whether the onset of depression was temporally linked to the perimenopause...
Premenstrual symptoms and perimenopausal depressionMisty Richards
Behavioral Endocrinology Branch, NIMH, NIH, U.S. Department of Health and Human Services, Bethesda, MD, USA
Am J Psychiatry 163:133-7. 2006..However, neither menses-related symptom cyclicity nor premenstrual dysphoria was an invariant accompaniment of perimenopausal depression. Additionally, the rate of premenstrual dysphoria was not predicted by initial self-reports...
Shyness, social anxiety, and impaired self-esteem in Turner syndrome and premature ovarian failurePeter J Schmidt
JAMA 295:1374-6. 2006
Effects of ovarian hormones on human cortical excitabilityMark J Smith
Brain Stimulation Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1430, USA
Ann Neurol 51:599-603. 2002..These findings demonstrate an excitatory neuronal effect associated with estradiol and confirm our earlier finding of inhibition associated with progesterone...
