David T Rubin

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. pmc Surveillance of dysplasia in inflammatory bowel disease: The gastroenterologist-pathologist partnership
    David T Rubin
    Department of Medicine, University of Chicago, Chicago, Illinois, USA
    Clin Gastroenterol Hepatol 4:1309-13. 2006
  2. ncbi request reprint The peri-appendiceal red patch in ulcerative colitis: review of the University of Chicago experience
    David T Rubin
    University of Chicago Inflammatory Bowel Disease Center, 5841 S Maryland Ave MC4076, Chicago, IL 60637, USA
    Dig Dis Sci 55:3495-501. 2010
  3. doi request reprint An updated approach to dysplasia in IBD
    David T Rubin
    University of Chicago Medical Center, 5841 S Maryland Ave, MC 4076, Chicago, IL 60637, USA
    J Gastrointest Surg 12:2153-6. 2008
  4. doi request reprint Impact of ulcerative colitis from patients' and physicians' perspectives: Results from the UC: NORMAL survey
    David T Rubin
    Section of Gastroenterology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA
    Inflamm Bowel Dis 15:581-8. 2009
  5. ncbi request reprint Colorectal cancer in inflammatory bowel disease: molecular and clinical considerations
    David T Rubin
    Reva and David Logan Center for Research in Gastroenterology, The University of Chicago, 5841 South Maryland Avenue, MC 4076, Chicago, IL 60637, USA
    Curr Treat Options Gastroenterol 9:211-20. 2006
  6. doi request reprint Positron emission tomography (PET) used to image subclinical inflammation associated with ulcerative colitis (UC) in remission
    David T Rubin
    Inflammatory Bowel Disease Center, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60637, USA
    Inflamm Bowel Dis 15:750-5. 2009
  7. pmc Outcome after surveillance of low-grade and indefinite dysplasia in patients with ulcerative colitis
    Joel R Pekow
    University of Chicago, Section of Gastroenterology, Hepatology, and Nutrition, Chicago, Illinois, USA
    Inflamm Bowel Dis 16:1352-6. 2010
  8. ncbi request reprint Are dysplasia and colorectal cancer endoscopically visible in patients with ulcerative colitis?
    David T Rubin
    The Reva and David Logan Gastrointestinal Clinical Research Center at the University of Chicago, Chicago, Illinois 60637, USA
    Gastrointest Endosc 65:998-1004. 2007
  9. doi request reprint The impact of ulcerative colitis on patients' lives compared to other chronic diseases: a patient survey
    David T Rubin
    Section of Gastroenterology, Department of Medicine, University of Chicago Medical Center, 5841 South Maryland Avenue, MC 4076, Chicago, IL, 60637, USA
    Dig Dis Sci 55:1044-52. 2010
  10. doi request reprint Identification of patients at increased risk for colorectal cancer in an open access endoscopy center
    Jeffrey W Nathanson
    Section of Gastroenterology, University of Chicago Medical Center, Chicago, IL 60637, USA
    J Clin Gastroenterol 42:1025-31. 2008

Detail Information

Publications66

  1. pmc Surveillance of dysplasia in inflammatory bowel disease: The gastroenterologist-pathologist partnership
    David T Rubin
    Department of Medicine, University of Chicago, Chicago, Illinois, USA
    Clin Gastroenterol Hepatol 4:1309-13. 2006
    ..We address the challenge of management of polypoid lesions and incorporate new information about degree of inflammation as an additional risk of neoplasia in these patients...
  2. ncbi request reprint The peri-appendiceal red patch in ulcerative colitis: review of the University of Chicago experience
    David T Rubin
    University of Chicago Inflammatory Bowel Disease Center, 5841 S Maryland Ave MC4076, Chicago, IL 60637, USA
    Dig Dis Sci 55:3495-501. 2010
    ..The clinical significance and prognostic implications of this finding are unknown. We used a tertiary care center database to review the clinical characteristics of UC patients with PARP...
  3. doi request reprint An updated approach to dysplasia in IBD
    David T Rubin
    University of Chicago Medical Center, 5841 S Maryland Ave, MC 4076, Chicago, IL 60637, USA
    J Gastrointest Surg 12:2153-6. 2008
    ....
  4. doi request reprint Impact of ulcerative colitis from patients' and physicians' perspectives: Results from the UC: NORMAL survey
    David T Rubin
    Section of Gastroenterology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA
    Inflamm Bowel Dis 15:581-8. 2009
    ..Two national internet surveys were conducted to understand how patients perceive the impact of ulcerative colitis (UC) relative to gastroenterologists...
  5. ncbi request reprint Colorectal cancer in inflammatory bowel disease: molecular and clinical considerations
    David T Rubin
    Reva and David Logan Center for Research in Gastroenterology, The University of Chicago, 5841 South Maryland Avenue, MC 4076, Chicago, IL 60637, USA
    Curr Treat Options Gastroenterol 9:211-20. 2006
    ..These include ursodeoxycholic acid (in patients with PSC and UC), aminosalicylates, and possibly statins...
  6. doi request reprint Positron emission tomography (PET) used to image subclinical inflammation associated with ulcerative colitis (UC) in remission
    David T Rubin
    Inflammatory Bowel Disease Center, Department of Medicine, University of Chicago Medical Center, Chicago, IL 60637, USA
    Inflamm Bowel Dis 15:750-5. 2009
    ..The aim of this study was to perform PET/computed tomography (CT) on patients with quiescent ulcerative colitis (UC) to understand the limits of this technology for assessing inflammatory activity...
  7. pmc Outcome after surveillance of low-grade and indefinite dysplasia in patients with ulcerative colitis
    Joel R Pekow
    University of Chicago, Section of Gastroenterology, Hepatology, and Nutrition, Chicago, Illinois, USA
    Inflamm Bowel Dis 16:1352-6. 2010
    ..The management of low-grade (LGD) and indefinite dysplasia (IND) in patients with ulcerative colitis (UC) remains controversial, as outcomes after a diagnosis of LGD or IND in previous studies vary widely...
  8. ncbi request reprint Are dysplasia and colorectal cancer endoscopically visible in patients with ulcerative colitis?
    David T Rubin
    The Reva and David Logan Gastrointestinal Clinical Research Center at the University of Chicago, Chicago, Illinois 60637, USA
    Gastrointest Endosc 65:998-1004. 2007
    ..Given the imperfect nature of this random approach, recent work has focused on improved surveillance techniques and suggests that neoplasia is endoscopically visible in many patients...
  9. doi request reprint The impact of ulcerative colitis on patients' lives compared to other chronic diseases: a patient survey
    David T Rubin
    Section of Gastroenterology, Department of Medicine, University of Chicago Medical Center, 5841 South Maryland Avenue, MC 4076, Chicago, IL, 60637, USA
    Dig Dis Sci 55:1044-52. 2010
    ..Overall, 451 patients with UC, 309 with rheumatoid arthritis, 305 with asthma, and 305 with migraine headaches were recruited in an Internet survey designed to assess a variety of disease-impact indices...
  10. doi request reprint Identification of patients at increased risk for colorectal cancer in an open access endoscopy center
    Jeffrey W Nathanson
    Section of Gastroenterology, University of Chicago Medical Center, Chicago, IL 60637, USA
    J Clin Gastroenterol 42:1025-31. 2008
    ..To determine whether patients referred for open access endoscopy (OAE) are being appropriately identified as "increased risk" or "average risk" for colorectal cancer (CRC) by referring physicians...
  11. doi request reprint Genetic testing for inflammatory bowel disease: focus group analysis of patients and family members
    Jeffrey R Lewis
    Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA
    Genet Test Mol Biomarkers 13:495-503. 2009
    ..Further, preferences and concerns of patients and their family members regarding a genetic test for this condition are not well studied...
  12. doi request reprint Association of colorectal cancer and prostate cancer and impact of radiation therapy
    Dezheng Huo
    Department of Health Studies, University of Chicago, Chicago, IL 60637, USA
    Cancer Epidemiol Biomarkers Prev 18:1979-85. 2009
    ..The decreased prostate cancer risk in men who received radiation therapy for rectal cancer may be related to the use of PSA for prostate cancer screening or the cure of occult prostate cancer...
  13. pmc Inflammation is an independent risk factor for colonic neoplasia in patients with ulcerative colitis: a case-control study
    David T Rubin
    Department of Medicine, University of Chicago Medical Center, Chicago, Illinois Electronic address
    Clin Gastroenterol Hepatol 11:1601-8.e1-4. 2013
    ..However, previous studies did not address the duration of inflammation or the effects of therapy on risk for CRN. We investigated the effects of inflammation, therapies, and characteristics of patients with UC on their risk for CRN...
  14. doi request reprint Safety and effectiveness of long-term allopurinol-thiopurine maintenance treatment in inflammatory bowel disease
    Frank Hoentjen
    Inflammatory Bowel Disease Center, University of Chicago, Chicago, Illinois, USA
    Inflamm Bowel Dis 19:363-9. 2013
    ..The aim of this study was to assess long-term maintenance effectiveness and tolerability of allopurinol-thiopurine therapy in a larger multicenter cohort of IBD patients...
  15. pmc miR-143 and miR-145 are downregulated in ulcerative colitis: putative regulators of inflammation and protooncogenes
    Joel R Pekow
    Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Illinois, USA
    Inflamm Bowel Dis 18:94-100. 2012
    ..We speculated that miR-143 and miR-145 might also be downregulated and contribute to malignant transformation of colonic epithelium in longstanding ulcerative colitis (UC)...
  16. doi request reprint Active Crohn's disease in the small bowel: evaluation by diffusion weighted imaging and quantitative dynamic contrast enhanced MR imaging
    Aytekin Oto
    Department of Radiology, The University of Chicago, Chicago, Illinois, USA
    J Magn Reson Imaging 33:615-24. 2011
    ..To determine relative diagnostic value of MR diffusion and perfusion parameters in detection of active small bowel inflammation in patients with Crohn's disease (CD)...
  17. ncbi request reprint Mucosal healing is associated with improved long-term outcome of maintenance therapy with natalizumab in Crohn's disease
    Atsushi Sakuraba
    Inflammatory Bowel Disease Center, The University of Chicago Medicine, Chicago, Illinois
    Inflamm Bowel Dis 19:2577-83. 2013
    ..We aimed to assess the impact of endoscopic severity and mucosal healing on the long-term outcome of natalizumab treatment in CD...
  18. pmc Long-term treatment of patients with a history of ulcerative colitis who develop gastritis and pan-enteritis after colectomy
    Frank Hoentjen
    Inflammatory Bowel Disease Center, University of Chicago Medical Center, Chicago, IL, USA
    J Clin Gastroenterol 47:52-7. 2013
    ..Corticosteroids are effective for induction of remission of this condition, but it is not clear how these patients should be managed long term...
  19. ncbi request reprint Effect of adalimumab on clinical laboratory parameters in patients with Crohn's disease: results from the CHARM trial
    David T Rubin
    University of Chicago Medical Center, Chicago, Illinois 60637, USA
    Inflamm Bowel Dis 18:818-25. 2012
    ..Nutritional deficiencies and anemia are common in Crohn's disease (CD)...
  20. pmc Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation
    Christopher R Weber
    Department of Pathology, University of Chicago, Chicago, IL 60637, USA
    Lab Invest 88:1110-20. 2008
    ..We speculate that increased claudin-1 and claudin-2 expression may be involved at early stages of transformation in IBD-associated neoplasia...
  21. pmc Rescue therapy with cyclosporine or infliximab is not associated with an increased risk for postoperative complications in patients hospitalized for severe steroid-refractory ulcerative colitis
    Ryan Nelson
    Section of Gastroenterology, Hepatology, and Nutrition, Department of Health Studies, The University of Chicago Medicine, Chicago, Illinois and Department of Surgery, University of Washington Medicine, Seattle, Washington
    Inflamm Bowel Dis 20:14-20. 2014
    ..Analyzing patients with acute severe UC, we compared the incidence of postoperative complications in patients who failed rescue therapy with cyclosporine or IFX with that in patients who received intravenous (IV) corticosteroids alone...
  22. ncbi request reprint Natalizumab in Crohn's disease: results from a US tertiary inflammatory bowel disease center
    Atsushi Sakuraba
    Inflammatory Bowel Disease Center, The University of Chicago Medicine, Chicago, Illinois 60637, USA
    Inflamm Bowel Dis 19:621-6. 2013
    ..We aimed to assess the efficacy and safety of natalizumab outside of clinical trial at a US tertiary center...
  23. doi request reprint Predictors of adalimumab dose escalation in patients with Crohn's disease at a tertiary referral center
    Russell D Cohen
    Inflammatory Bowel Disease Center, University of Chicago, Illinois, USA
    Inflamm Bowel Dis 18:10-6. 2012
    ..Our objective was to determine which patient-, disease-, and therapy-related factors were associated with DE in CD patients treated with ADA...
  24. ncbi request reprint A practical, evidence-based guide to the use of adalimumab in Crohn's disease
    David T Rubin
    University of Chicago Medical Center, Chicago, IL 60637, USA
    Curr Med Res Opin 27:1803-13. 2011
    ..Here we provide a practical, evidence-based guide to help clinicians optimize the use of adalimumab in patients with CD...
  25. ncbi request reprint Surveillance for cancer and dysplasia in inflammatory bowel disease
    David T Rubin
    Section of Gastroenterology, and the MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago, IL 60637, USA
    Gastroenterol Clin North Am 35:581-604. 2006
    ..In meantime, existing guidelines should be emphasized and ongoing education of clinicians and patients must occur...
  26. doi request reprint Quantitative analysis of dynamic contrast enhanced MRI for assessment of bowel inflammation in Crohn's disease pilot study
    Aytekin Oto
    Department of Radiology, University of Chicago, 5841 S Maryland Avenue, MC 2026, Chicago, IL 60637, USA
    Acad Radiol 16:1223-30. 2009
    ..The aim of this study was to evaluate the feasibility of quantitative analysis of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data in the detection of bowel inflammation in patients with Crohn's disease...
  27. ncbi request reprint Colonic infiltration with chronic myelomonocytic leukemia
    Andelka D LoSavio
    Section of Gastroenterology, Hepatology, and Nutrition, University of Chicago, Chicago, IL 60637, USA
    Nat Clin Pract Gastroenterol Hepatol 4:229-33. 2007
    ..Over several months, the patient's symptoms progressed, which resulted in significant weight loss. The patient's course of disease was ultimately complicated by acute disseminated encephalomyelitis and death...
  28. ncbi request reprint Colorectal cancer prevention in inflammatory bowel disease and the role of 5-aminosalicylic acid: a clinical review and update
    David T Rubin
    University of Chicago Medical Center, Chicago, IL 60637, USA
    Inflamm Bowel Dis 14:265-74. 2008
    ..This article provides a comprehensive overview of the issues discussed and should act as a guide to shaping the design of future studies in this area...
  29. pmc Fecal bacteriotherapy for ulcerative colitis: patients are ready, are we?
    Stacy A Kahn
    University of Chicago, Inflammatory Bowel Disease Center, Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology, and Nutrition, MacLean Center for Clinical Medical Ethics, Chicago, Illinois 60637, USA
    Inflamm Bowel Dis 18:676-84. 2012
    ..We performed a qualitative study to explore the attitudes and concerns of adult patients and parents of children with UC regarding FB as a potential treatment...
  30. pmc Secondary gastrointestinal cancer in childhood cancer survivors: a cohort study
    Tara O Henderson
    University of Chicago Department of Pediatrics, Section of Hematology, Oncology and Stem Cell Transplantation, 5841 South Maryland Avenue, MC 4060, Chicago, IL 60637, USA
    Ann Intern Med 156:757-66, W-260. 2012
    ..Childhood cancer survivors develop gastrointestinal cancer more frequently and at a younger age than the general population, but the risk factors have not been well-characterized...
  31. doi request reprint Association between colorectal cancer and urologic cancers
    Audrey H Calderwood
    Department of Medicine, Section of Gastroenterology, The University of Chicago Medical Center, Chicago, Illinois 60637, USA
    Arch Intern Med 168:1003-9. 2008
    ..We sought to quantify the risk for CRC after urologic cancer and the risk for urologic cancer after CRC in patients without known genetic syndromes...
  32. ncbi request reprint Do colorectal cancer patients understand that their family is at risk?
    David T Rubin
    The University of Chicago Medical Center, Chicago, IL, USA
    Dig Dis Sci 54:2473-83. 2009
    ..The aim of this study was to assess whether patients with colorectal cancer (CRC) are aware of the risk to family members and to test an educational intervention...
  33. ncbi request reprint Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis
    David T Rubin
    The Reva and David Logan Center for Research in Gastrointestinal Diseases, University of Chicago, Chicago, Illinois, USA
    Clin Gastroenterol Hepatol 4:1346-50. 2006
    ..Aminosalicylates have been suggested as chemopreventive agents for colorectal cancer (CRC) in ulcerative colitis (UC). We studied the effect of aminosalicylate use on dysplasia and CRC risk in chronic UC...
  34. pmc Colorectal cancer and dysplasia in inflammatory bowel disease
    Timothy L Zisman
    The University of Chicago Medical Center, Chicago, IL 60637, United States
    World J Gastroenterol 14:2662-9. 2008
    ....
  35. ncbi request reprint Performance of CT colonography in clinical trials
    Jonathan A Rosenberg
    Section of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Chicago Medical Center, 5841 South Maryland Avenue, MC 4076, Chicago, IL 60637 1463, USA
    Gastrointest Endosc Clin N Am 20:193-207. 2010
    ..The data suggest that CTC is effective especially for the detection of larger lesions and when more advanced imaging technology is used...
  36. ncbi request reprint Computerized detection of colonic polyps at CT colonography on the basis of volumetric features: pilot study
    Hiroyuki Yoshida
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Radiology 222:327-36. 2002
    ..To develop a computer-aided diagnosis (CAD) scheme for automated detection of colonic polyps on the basis of volumetric features and to assess its accuracy on the basis of colonoscopy, the standard...
  37. ncbi request reprint Computer-aided diagnosis scheme for detection of polyps at CT colonography
    Hiroyuki Yoshida
    Department of Radiology, University of Chicago, 5841 S Maryland Ave, MC20206, IL 60637, USA
    Radiographics 22:963-79. 2002
    ..This CAD scheme permits accurate detection of suspicious lesions and thus has the potential to reduce radiologists' interpretation time and improve their diagnostic accuracy in the detection of polyps at CT colonography...
  38. ncbi request reprint Assessment of the relationship between quality of sleep and disease activity in inflammatory bowel disease patients
    Tauseef Ali
    OU Physicians Inflammatory Bowel Disease Center, Oklahoma City, Oklahoma Section of Digestive Diseases and Nutrition, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma Lynn Health Science Institute, Oklahoma City, Oklahoma University of Chicago Inflammatory Bowel Disease Center, Chicago, Illinois and College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
    Inflamm Bowel Dis 19:2440-3. 2013
    ..Sleep disturbances can impact the immune function and process of inflammation. The relationship between sleep quality and the inflammatory bowel disease (IBD) has not been well studied...
  39. pmc Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease
    Uma Mahadevan
    Division of Gastroenterology, Department of Medicine, University of California, San Francisco, California 94115, USA
    Clin Gastroenterol Hepatol 11:286-92; quiz e24. 2013
    ..It is not clear whether these drugs are transferred to the fetus via the placenta and then cleared, or whether structurally different TNF antagonists have different rates of transfer...
  40. ncbi request reprint Infectious proctitis: when to suspect it is not inflammatory bowel disease
    Frank Hoentjen
    Inflammatory Bowel Disease Center, University of Chicago Medical Center, 5841 S Maryland Avenue, MC4076, Chicago, IL 60637, USA
    Dig Dis Sci 57:269-73. 2012
    ..The most frequently reported pathogens include Neisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum, and herpes simplex...
  41. doi request reprint Curbing our enthusiasm for fecal transplantation in ulcerative colitis
    David T Rubin
    Inflammatory Bowel Disease Center, Associate Faculty, MacLean Center for Clinical Medical Ethics, University of Chicago Medicine, Chicago, Illinois, USA
    Am J Gastroenterol 108:1631-3. 2013
    ..I discuss the important observations from this study and point out that the lack of clinical efficacy and observed side effects warrant caution in the ongoing pursuit of this treatment option. ..
  42. pmc Patient perceptions of fecal microbiota transplantation for ulcerative colitis
    Stacy A Kahn
    Section of Pediatric Gastroenterology, Hepatology, and Nutrition, University of Chicago, 5841 South Maryland Avenue, MC 4065, Chicago, IL 60637, USA
    Inflamm Bowel Dis 19:1506-13. 2013
    ..Our objective was to describe patient interest in and social concerns around FMT...
  43. doi request reprint Low-dose smoking resumption in ex-smokers with refractory ulcerative colitis
    Emma Calabrese
    Section of Gastroenterology, Hepatology and Nutrition, University of Chicago, Chicago, IL 60637, USA
    J Crohns Colitis 6:756-62. 2012
    ..We report outcomes of ex-smokers with refractory UC who resumed low-dose cigarette smoking...
  44. ncbi request reprint p53 mutations are associated with dysplasia and progression of dysplasia in patients with Crohn's disease
    Jeffrey W Nathanson
    Reva and David Logan Gastrointestinal Clinical Research Center at the University of Chicago, Chicago, IL, USA
    Dig Dis Sci 53:474-80. 2008
    ..Mutations in the tumor suppressor gene p53 are associated with neoplasia in ulcerative colitis, but little is understood of their significance in Crohn's disease (CD)...
  45. ncbi request reprint The complexity and challenges of genetic counseling and testing for inflammatory bowel disease
    Shelly A Cummings
    Cancer Risk Clinic, The University of Chicago, Section of Hematology Oncology, 5841 South Maryland Avenue, MC 2115, Chicago, IL 60637, USA
    J Genet Couns 15:465-76. 2006
    ..Effective incorporation of clinical genetic testing for IBD into practice will require appropriate education and counseling...
  46. pmc Rifaximin Is Effective for the Treatment of Clostridium difficile-Associated Diarrhea: Results of an Open-Label Pilot Study
    David T Rubin
    University of Chicago Medical Center, Chicago, IL 60637, USA
    Gastroenterol Res Pract 2011:106978. 2011
    ..One patient had recurrent CDAD during a repeat hospitalization. Conclusions. Rifaximin was effective and safe as first-line treatment for CDAD and did not result in recurrence in most patients...
  47. ncbi request reprint What is the most effective way to communicate results after endoscopy?
    David T Rubin
    Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Gastrointest Endosc 66:108-12. 2007
    ....
  48. ncbi request reprint Fever and right upper quadrant pain in a pregnant woman at 30 weeks' gestation
    Laura E Harrell
    Section of Gastroenterology and Nutrition, University of Chicago, IL, USA
    Nat Clin Pract Gastroenterol Hepatol 1:113-6; quiz 1 p following 116. 2004
    ..Ultimately, a CT scan revealed marked thickening of the distal ileum and confirmed diagnosis of an abscess in continuity with the inflamed bowel...
  49. ncbi request reprint Quality indicators for inflammatory bowel disease: development of process and outcome measures
    Gil Y Melmed
    Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Inflamm Bowel Dis 19:662-8. 2013
    ..The RAND/UCLA appropriateness method was used to develop a set of process and outcome QIs to define quality of care for IBD...
  50. doi request reprint Response to biologic therapy in Crohn's disease is improved with early treatment: an analysis of health claims data
    David T Rubin
    University of Chicago Inflammatory Bowel Disease Center, Chicago, Illinois 60637, USA
    Inflamm Bowel Dis 18:2225-31. 2012
    ..The aim of this study was to determine if a top-down approach with anti-TNF therapy is associated with improved outcomes for patients with active CD...
  51. doi request reprint Total abdominal colectomy for refractory ulcerative colitis. Surgical treatment in evolution
    Alessandro Fichera
    Department of Surgery, University of Chicago Medical Center, Chicago, IL 60637, USA
    J Gastrointest Surg 15:1909-16. 2011
    ..This study illustrates the laparoscopic evolution towards a truly minimally invasive approach comparing three phases of a single colorectal surgeon experience...
  52. doi request reprint Medical professionalism and the doctor-patient relationship
    Lydia S Dugdale
    Department of Medicine, Yale New Haven Hospital, New Haven, CT, USA
    Perspect Biol Med 51:547-53. 2008
    ....
  53. ncbi request reprint Comparison of routine and unprepped CT colonography augmented by low fiber diet and stool tagging: a pilot study
    Abraham H Dachman
    Department of Radiology, The University of Chicago, MC 2026, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Abdom Imaging 32:96-104. 2007
    ..Prior reports of tagging were limited in that the residual stool was neither measured and stratified by size nor did prior reports subjectively evaluate the ease of interpretation by a reader experienced in interpreting CTC examinations...
  54. pmc Two brothers with skewed thiopurine metabolism in ulcerative colitis treated successfully with allopurinol and mercaptopurine dose reduction
    Frank Hoentjen
    Inflammatory Bowel Disease Center, University of Chicago, Chicago, IL, USA
    Dig Dis Sci 57:250-3. 2012
    ....
  55. ncbi request reprint Role of antibiotics in the management of inflammatory bowel disease: a review
    David T Rubin
    Reva and David Logan Inflammatory Bowel Disease Center, University of Chicago, Chicago, Illinois, USA
    Rev Gastroenterol Disord 5:S10-5. 2005
    ..A proposal for future therapies is provided that might include a combination therapy aimed at both a reduction in pathogenetic bacteria and immune modulation to achieve the most durable remission of disease...
  56. ncbi request reprint Do patients with inflammatory bowel disease want genetic testing?
    Vani Konda
    Reva and David Logan Gastrointestinal Clinical Research Center, University of Chicago, Chicago, Illinois 60637, USA
    Inflamm Bowel Dis 12:497-502. 2006
    ..Thus, the goal of this study was to assess the interest of patients with IBD in genetic testing and their willingness to accept the uncertainty inherent in complex genetics...
  57. ncbi request reprint Superior mesenteric vein thrombosis after colectomy in a patient with Crohn's disease
    Andrew S Ross
    Department of Surgery, University of Chicago, IL, USA
    Nat Clin Pract Gastroenterol Hepatol 2:281-5; quiz 1 p following 285. 2005
    ..Azathioprine was added to the treatment regimen and the patient tapered off prednisone. At this stage the patient continued to do well clinically up until presentation...
  58. ncbi request reprint To test or "NOD-2" test: what are the questions? The balanced viewpoint
    David T Rubin
    Section of Gastroenterology, Reva and David Logan Center for Inflammatory Bowel Disease, The MacLean Center for Clinical Medical Ethics, University of Chicago, Illinois, USA
    Inflamm Bowel Dis 11:510-2. 2005
  59. ncbi request reprint Prospective comparison of patient experience with colon imaging tests
    Hayden B Bosworth
    Center for Health Services Research in Primary Care, Durham VA Medical Center, Durham, NC, USA
    Am J Med 119:791-9. 2006
    ..We examined differences in patient experience with colon imaging tests and whether they varied with gender, age, and race...
  60. ncbi request reprint Maximizing patient adherence and clinical outcomes with mesalamine in mildly-to-moderately active ulcerative colitis
    Gary R Lichtenstein
    Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Rev Gastroenterol Disord 8:21-30; quiz 31-2. 2008
    ..Novel formulations of mesalamine and newly devised, high-dose regimens offer additional therapeutic options and may lead to improved treatment adherence, longer-lasting periods of remission, and enhanced patient well-being...
  61. ncbi request reprint 5-Aminosalicylic acid therapy and the risk of colorectal cancer among patients with inflammatory bowel disease
    Jonathan P Terdiman
    University of California, San Francisco, San Francisco, California 94143 1623, USA
    Inflamm Bowel Dis 13:367-71. 2007
    ..The objective of this observational study was to determine if an association between 5-ASA therapy and CRC risk exists in IBD patients...
  62. ncbi request reprint The changing face of colorectal cancer in inflammatory bowel disease: progress at last!
    David T Rubin
    Gastroenterology 130:1350-2. 2006
  63. ncbi request reprint The challenge of compliance and persistence: focus on ulcerative colitis
    Sunanda V Kane
    Mayo Clinic College of Medicine, Division of Gastroenterology and Hepatology, 200 First Street, SW, 19th Floor, Rochester, MN 55905, USA
    J Manag Care Pharm 14:s2-12; quiz s13-5. 2008
    ..An estimated 20% to 50% of patients with ulcerative colitis (UC) do not take their medications as prescribed, resulting in higher disease-recurrence rates and potentially higher health care costs...
  64. ncbi request reprint Will a 5-ASA a day keep the cancer (and dysplasia) away?
    David T Rubin
    Am J Gastroenterol 100:1354-6. 2005
    ..The authors conclude that the safety and current maintenance use of 5-ASA warrant its acceptance as a probable chemopreventive agent at this time...
  65. ncbi request reprint The case: can doctors say "enough"?
    Jeffrey S Groeger
    Intensive Care Unit, Memorial Sloan Kettering Cancer Center, New York City, USA
    Camb Q Healthc Ethics 12:215-23. 2003
  66. ncbi request reprint Inflammation's role in rectal cancer following prostate radiotherapy, and emerging evidence for a protective role for balsalazide
    Christopher D Jahraus
    Gastroenterology 129:770-2. 2005