Joel H Rubenstein

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. doi request reprint Epidemiology of gastroesophageal reflux disease
    Joel H Rubenstein
    Veterans Affairs Center for Clinical Management Research, Ann Arbor, MI, USA Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, MI, USA Electronic address
    Gastroenterol Clin North Am 43:1-14. 2014
  2. pmc Association between Helicobacter pylori and Barrett's esophagus, erosive esophagitis, and gastroesophageal reflux symptoms
    Joel H Rubenstein
    Center for Clinical Management Research, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Electronic address
    Clin Gastroenterol Hepatol 12:239-45. 2014
  3. pmc Associations of diabetes mellitus, insulin, leptin, and ghrelin with gastroesophageal reflux and Barrett's esophagus
    Joel H Rubenstein
    Center for Clinical Management Research, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Electronic address
    Gastroenterology 145:1237-44.e1-5. 2013
  4. pmc Prediction of Barrett's esophagus among men
    Joel H Rubenstein
    Center for Clinical Management Research, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan 48109, USA
    Am J Gastroenterol 108:353-62. 2013
  5. pmc Association of adiponectin multimers with Barrett's oesophagus
    J H Rubenstein
    VA Medical Center 111 D, Ann Arbor, MI 48105, USA
    Gut 58:1583-9. 2009
  6. pmc Esophageal adenocarcinoma incidence in individuals with gastroesophageal reflux: synthesis and estimates from population studies
    Joel H Rubenstein
    Veterans Affairs Center of Excellence for Clinical Management Research, Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    Am J Gastroenterol 106:254-60. 2011
  7. pmc Meta-analysis: the association of oesophageal adenocarcinoma with symptoms of gastro-oesophageal reflux
    J H Rubenstein
    Veterans Affairs Center of Excellence for Clinical Management Research, Ann Arbor, MI, USA
    Aliment Pharmacol Ther 32:1222-7. 2010
  8. pmc Cost effectiveness of ulcerative colitis surveillance in the setting of 5-aminosalicylates
    Joel H Rubenstein
    The Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Am J Gastroenterol 104:2222-32. 2009
  9. pmc Age- and sex-specific yield of Barrett's esophagus by endoscopy indication
    Joel H Rubenstein
    Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan 48105, USA
    Gastrointest Endosc 71:21-7. 2010
  10. pmc Validation of a new physical activity questionnaire for a sedentary population
    Joel H Rubenstein
    VA Medical Center 111 D, 2215 Fuller Road, Ann Arbor, MI 48105, USA
    Dig Dis Sci 56:2678-87. 2011

Research Grants

Detail Information

Publications36

  1. doi request reprint Epidemiology of gastroesophageal reflux disease
    Joel H Rubenstein
    Veterans Affairs Center for Clinical Management Research, Ann Arbor, MI, USA Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, MI, USA Electronic address
    Gastroenterol Clin North Am 43:1-14. 2014
    ..Risk factors for GERD include obesity, poor diet, lack of physical activity, consumption of tobacco and alcohol, and respiratory diseases. ..
  2. pmc Association between Helicobacter pylori and Barrett's esophagus, erosive esophagitis, and gastroesophageal reflux symptoms
    Joel H Rubenstein
    Center for Clinical Management Research, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Electronic address
    Clin Gastroenterol Hepatol 12:239-45. 2014
    ..We aimed to determine whether H pylori infection is associated with GERD symptoms, erosive esophagitis, and Barrett's esophagus within the same cohort...
  3. pmc Associations of diabetes mellitus, insulin, leptin, and ghrelin with gastroesophageal reflux and Barrett's esophagus
    Joel H Rubenstein
    Center for Clinical Management Research, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan Electronic address
    Gastroenterology 145:1237-44.e1-5. 2013
    ..We assessed whether diabetes mellitus and serum levels of insulin, leptin, and ghrelin are associated with gastroesophageal reflux disease (GERD) and Barrett's esophagus...
  4. pmc Prediction of Barrett's esophagus among men
    Joel H Rubenstein
    Center for Clinical Management Research, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan 48109, USA
    Am J Gastroenterol 108:353-62. 2013
    ..Risk factors for Barrett's esophagus include gastroesophageal reflux disease (GERD) symptoms, age, abdominal obesity, and tobacco use. We aimed to develop a tool using these factors to predict the presence of Barrett's esophagus...
  5. pmc Association of adiponectin multimers with Barrett's oesophagus
    J H Rubenstein
    VA Medical Center 111 D, Ann Arbor, MI 48105, USA
    Gut 58:1583-9. 2009
    ..We postulated that circulating levels of adiponectin and its multimers would be associated with the risk of Barrett's oesophagus...
  6. pmc Esophageal adenocarcinoma incidence in individuals with gastroesophageal reflux: synthesis and estimates from population studies
    Joel H Rubenstein
    Veterans Affairs Center of Excellence for Clinical Management Research, Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    Am J Gastroenterol 106:254-60. 2011
    ..We aimed to estimate the symptom-, age-, and sex-specific incidences of EAC, and place these incidences in the perspective of other cancers for which screening is endorsed...
  7. pmc Meta-analysis: the association of oesophageal adenocarcinoma with symptoms of gastro-oesophageal reflux
    J H Rubenstein
    Veterans Affairs Center of Excellence for Clinical Management Research, Ann Arbor, MI, USA
    Aliment Pharmacol Ther 32:1222-7. 2010
    ..Assessing the net benefits of such a strategy requires a precise understanding of the cancer risk in the screened population...
  8. pmc Cost effectiveness of ulcerative colitis surveillance in the setting of 5-aminosalicylates
    Joel H Rubenstein
    The Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Am J Gastroenterol 104:2222-32. 2009
    ..Therefore, in patients prescribed 5-ASAs for maintenance of remission, annual surveillance might be overly burdensome and inefficient. We aimed to determine the ideal frequency of surveillance in patients with UC maintained on 5-ASAs...
  9. pmc Age- and sex-specific yield of Barrett's esophagus by endoscopy indication
    Joel H Rubenstein
    Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan 48105, USA
    Gastrointest Endosc 71:21-7. 2010
    ..Screening GERD patients for Barrett's esophagus has been suggested, but it is not known which patients should be screened and at what age...
  10. pmc Validation of a new physical activity questionnaire for a sedentary population
    Joel H Rubenstein
    VA Medical Center 111 D, 2215 Fuller Road, Ann Arbor, MI 48105, USA
    Dig Dis Sci 56:2678-87. 2011
    ..Many available physical activity questionnaires (PAQs) are limited due to either focus on recreational activities or burdensome length...
  11. ncbi request reprint A clinical and economic evaluation of endoscopic ultrasound for patients at risk for familial pancreatic adenocarcinoma
    Joel H Rubenstein
    Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI 48105, USA
    Pancreatology 7:514-25. 2007
    ..Approximately 50% of 1st-degree relatives (FDRs) have endoscopic ultrasound (EUS) findings of chronic pancreatitis. We modeled the natural history of these patients to compare 4 management strategies...
  12. ncbi request reprint Oesophageal hypersensitivity is associated with features of psychiatric disorders and the irritable bowel syndrome
    J H Rubenstein
    Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, MI 48109 0362, USA
    Aliment Pharmacol Ther 26:443-52. 2007
    ..We hypothesized that such PPI non-responders have heightened oesophageal sensation, and that oesophageal hypersensitivity is associated with psychiatric features including somatization and anxiety...
  13. ncbi request reprint Cost utility of screening for Barrett's esophagus with esophageal capsule endoscopy versus conventional upper endoscopy
    Joel H Rubenstein
    Division of Gastroenterology, University of Michigan Medical School, and the Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan 48105, USA
    Clin Gastroenterol Hepatol 5:312-8. 2007
    ..Esophageal capsule endoscopy (ECE) has recently been shown to be accurate in detecting Barrett's esophagus. We aimed to compare the cost-effectiveness of screening by ECE with screening by EGD...
  14. ncbi request reprint Defining a clinically significant adverse impact of diagnosing Barrett's esophagus
    Joel H Rubenstein
    Division of Gastroenterology, University of Michigan Health System and Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI 48105, USA
    J Clin Gastroenterol 40:109-15. 2006
    ..It is unknown whether the mere diagnosis of Barrett's esophagus (BE) adversely impacts patients' preferences (health-state utility) sufficiently to impair the cost-effectiveness of endoscopic screening for esophageal adenocarcinoma...
  15. ncbi request reprint Relationship between diabetes mellitus and adenocarcinoma of the oesophagus and gastric cardia
    J H Rubenstein
    The Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, MI, USA
    Aliment Pharmacol Ther 22:267-71. 2005
    ..Obesity is a risk factor for adenocarcinomas of the oesophagus and gastric cardia. Diabetes mellitus might mediate that association...
  16. ncbi request reprint The cost-effectiveness of biomarkers for predicting the development of oesophageal adenocarcinoma
    J H Rubenstein
    University of Michigan Health System, Ann Arbor, MI, USA
    Aliment Pharmacol Ther 22:135-46. 2005
    ..The recommended surveillance strategy for oesophageal adenocarcinoma may prevent as few as 50% of cancer deaths. Tissue biomarkers have been proposed to identify high-risk patients...
  17. ncbi request reprint Systematic review: the hepatotoxicity of non-steroidal anti-inflammatory drugs
    J H Rubenstein
    Division of Gastroenterology, University of Michigan Health System, Ann Arbor, MI 48109 0362, USA
    Aliment Pharmacol Ther 20:373-80. 2004
    ..Non-steroidal anti-inflammatory drugs have been implicated in reports of liver injury. However, the precise risk of non-steroidal anti-inflammatory drugs for this rare complication is unknown...
  18. pmc The yield of colonoscopy in patients with non-constipated irritable bowel syndrome: results from a prospective, controlled US trial
    William D Chey
    Divison of Gastroenterology, University of Michigan Health System, Ann Arbor, Michigan, USA
    Am J Gastroenterol 105:859-65. 2010
    ..This study compared the prevalence of structural colonic lesions in patients with suspected non-constipation-predominant IBS and healthy volunteers. We also determined the yield of rectosigmoid biopsies in patients with suspected IBS...
  19. doi request reprint Protective role of gluteofemoral obesity in erosive oesophagitis and Barrett's oesophagus
    Joel H Rubenstein
    Center for Clinical Management Research, Veterans Affairs Medical Center, Ann Arbor, Michigan, USA
    Gut 63:230-5. 2014
    ..As gluteofemoral obesity protects against diabetes mellitus and cardiovascular disease, we hypothesised that gluteofemoral obesity would be inversely associated with EO and BO...
  20. ncbi request reprint A pilot study of the association of low plasma adiponectin and Barrett's esophagus
    Joel H Rubenstein
    Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI 48105, USA
    Am J Gastroenterol 103:1358-64. 2008
    ..We aimed to estimate the effect of circulating adiponectin on the risk of Barrett's esophagus (BE), an accepted precursor of EAC, controlling for GERD symptoms and other potential confounders...
  21. pmc A survey of expert follow-up practices after successful endoscopic eradication therapy for Barrett's esophagus with high-grade dysplasia and intramucosal adenocarcinoma
    Aarti O Bedi
    Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Gastrointest Endosc 78:696-701. 2013
    ....
  22. pmc Effect of a prior endoscopy on outcomes of esophageal adenocarcinoma among United States veterans
    Joel H Rubenstein
    Gastroenterology Section, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan 48105, USA
    Gastrointest Endosc 68:849-55. 2008
    ..The efficacy of screening and surveillance EGD for esophageal adenocarcinoma (EAC) is controversial...
  23. ncbi request reprint Influence of malpractice history on the practice of screening and surveillance for Barrett's esophagus
    Joel H Rubenstein
    Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan 48105, USA
    Am J Gastroenterol 103:842-9. 2008
    ..We hypothesized that financial incentives and concerns over malpractice litigation influence gastroenterologists' usual practices regarding screening and surveillance...
  24. pmc Knowledge of hepatocellular carcinoma screening guidelines and clinical practices among gastroenterologists
    Pratima Sharma
    Division of Gastroenterology, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109, USA
    Dig Dis Sci 56:569-77. 2011
    ..Our aim was to assess gastroenterologists' knowledge of HCC management guidelines established by the American Association for the Study of Liver Diseases (AASLD) and usual clinical practice...
  25. ncbi request reprint Evidence based medicine (EBM) in practice: applying results of cost-effectiveness analyses
    Joel H Rubenstein
    Division of Gastroenterology, University of Michigan School of Medicine, and Ann Arbor Veterans Administration Medical Center, Michigan 48105, USA
    Am J Gastroenterol 101:1169-71. 2006
  26. pmc The impact of rotating shift work on the prevalence of irritable bowel syndrome in nurses
    Borko Nojkov
    Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan 48105, USA
    Am J Gastroenterol 105:842-7. 2010
    ....
  27. pmc Meta-analyses of the effect of symptoms of gastroesophageal reflux on the risk of Barrett's esophagus
    Justin B Taylor
    Michigan Institute for Clinical and Health Research, Ann Arbor, Michigan, USA
    Am J Gastroenterol 105:1729, 1730-7; quiz 1738. 2010
    ..We hypothesized that studies of higher-quality design show weaker associations of GERD with BE, and that GERD is only weakly associated with short-segment Barrett's esophagus (SSBE)...
  28. pmc Factors associated with esophageal stricture formation after endoscopic mucosal resection for neoplastic Barrett's esophagus
    Jason J Lewis
    University of Michigan Health System, Ann Arbor Michigan, USA
    Gastrointest Endosc 74:753-60. 2011
    ..EMR for early neoplastic Barrett's esophagus is gaining favor over esophagectomy. Esophageal stricture development has been reported as a common complication of EMR, photodynamic therapy, and combination endoscopic therapy...
  29. doi request reprint Barrett's esophagus: prevalence-incidence and etiology-origins
    Gary W Falk
    Department of Medicine, Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Ann N Y Acad Sci 1232:1-17. 2011
    ..Gastroesophageal reflux disease may be considered an immune-mediated disease starting at the submucosal layer; the cytokine profile of the mucosal immune response may explain the different outcome of gastroesophageal reflux...
  30. ncbi request reprint A cost-utility analysis of secondary prophylaxis for variceal hemorrhage
    Joel H Rubenstein
    Division of Gastroenterology, University of Michigan Health System, Ann Arbor, Michigan 48109 0362, USA
    Am J Gastroenterol 99:1274-88. 2004
    ..Secondary prophylaxis for esophageal variceal hemorrhage (VH) is recommended, but there has never been a cost-utility analysis of its implementation...
  31. pmc Helicobacter pylori DNA decreases pro-inflammatory cytokine production by dendritic cells and attenuates dextran sodium sulphate-induced colitis
    Jay Luther
    Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109 5682, USA
    Gut 60:1479-86. 2011
    ..However, the mechanism for the observed inverse association between H pylori and IBD has not been described...
  32. ncbi request reprint The influence of co-morbid IBS and psychological distress on outcomes and quality of life following PPI therapy in patients with gastro-oesophageal reflux disease
    B Nojkov
    Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, MI, USA
    Aliment Pharmacol Ther 27:473-82. 2008
    ..A subset of patients with gastro-oesophageal reflux disease (GERD) does not achieve complete symptom resolution with proton pump inhibitor (PPI) therapy. The factors which affect response to PPI therapy in GERD patients remain unclear...
  33. ncbi request reprint The synergistic effects of alcohol and tobacco consumption on the risk of esophageal squamous cell carcinoma: a meta-analysis
    Anoop Prabhu
    VA Medical Center, Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Am J Gastroenterol 109:822-7. 2014
    ..Tobacco and alcohol use are established risk factors for esophageal squamous cell carcinoma (ESCC). We sought to determine whether these factors act synergistically to increase the risk of ESCC...
  34. pmc Radiation doses to ERCP patients are significantly lower with experienced endoscopists
    Jennifer E Jorgensen
    Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan 48109 5362, USA
    Gastrointest Endosc 72:58-65. 2010
    ..Patients undergoing ERCP receive nontrivial doses of radiation, which may increase their risk of developing cancer, especially young patients. Radiation doses to patients during ERCP correlate closely with fluoroscopy time...
  35. ncbi request reprint Dysphagia drives doctors to diagnose a disease: pitfalls in interpreting observational studies
    Joel H Rubenstein
    Gastrointest Endosc 61:809-11. 2005
  36. ncbi request reprint Infliximab decreases resource use among patients with Crohn's disease
    Joel H Rubenstein
    University of Chicago Hospitals, Chicago, Illinois 60637, U S A
    J Clin Gastroenterol 35:151-6. 2002
    ..Infliximab induces remission and heals fistulas in CD but is more costly than traditional therapies. Its impact upon resource use in CD is unknown...

Research Grants2

  1. The Epidemiology of Adipokines in Barrett's Esophagus
    Joel Rubenstein; Fiscal Year: 2007
    ..If so, measurement of these substances may be useful in a screening program. ..