Research Topics
| Joel H RubensteinSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Prediction of Barrett's esophagus among menJoel H Rubenstein
Center for Clinical Management Research, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan 48109, USA
Am J Gastroenterol 108:353-62. 2013..Risk factors for Barrett's esophagus include gastroesophageal reflux disease (GERD) symptoms, age, abdominal obesity, and tobacco use. We aimed to develop a tool using these factors to predict the presence of Barrett's esophagus...
Validation of a new physical activity questionnaire for a sedentary populationJoel H Rubenstein
VA Medical Center 111 D, 2215 Fuller Road, Ann Arbor, MI 48105, USA
Dig Dis Sci 56:2678-87. 2011..Many available physical activity questionnaires (PAQs) are limited due to either focus on recreational activities or burdensome length...
Esophageal adenocarcinoma incidence in individuals with gastroesophageal reflux: synthesis and estimates from population studiesJoel H Rubenstein
Veterans Affairs Center of Excellence for Clinical Management Research, Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
Am J Gastroenterol 106:254-60. 2011..We aimed to estimate the symptom-, age-, and sex-specific incidences of EAC, and place these incidences in the perspective of other cancers for which screening is endorsed...
Meta-analysis: the association of oesophageal adenocarcinoma with symptoms of gastro-oesophageal refluxJ H Rubenstein
Veterans Affairs Center of Excellence for Clinical Management Research, Ann Arbor, MI, USA
Aliment Pharmacol Ther 32:1222-7. 2010..Assessing the net benefits of such a strategy requires a precise understanding of the cancer risk in the screened population...
Age- and sex-specific yield of Barrett's esophagus by endoscopy indicationJoel H Rubenstein
Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan 48105, USA
Gastrointest Endosc 71:21-7. 2010..Screening GERD patients for Barrett's esophagus has been suggested, but it is not known which patients should be screened and at what age...
Association of adiponectin multimers with Barrett's oesophagusJ H Rubenstein
VA Medical Center 111 D, Ann Arbor, MI 48105, USA
Gut 58:1583-9. 2009..We postulated that circulating levels of adiponectin and its multimers would be associated with the risk of Barrett's oesophagus...
Cost effectiveness of ulcerative colitis surveillance in the setting of 5-aminosalicylatesJoel H Rubenstein
The Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Am J Gastroenterol 104:2222-32. 2009..Therefore, in patients prescribed 5-ASAs for maintenance of remission, annual surveillance might be overly burdensome and inefficient. We aimed to determine the ideal frequency of surveillance in patients with UC maintained on 5-ASAs...
A clinical and economic evaluation of endoscopic ultrasound for patients at risk for familial pancreatic adenocarcinomaJoel H Rubenstein
Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI 48105, USA
Pancreatology 7:514-25. 2007..Approximately 50% of 1st-degree relatives (FDRs) have endoscopic ultrasound (EUS) findings of chronic pancreatitis. We modeled the natural history of these patients to compare 4 management strategies...
Oesophageal hypersensitivity is associated with features of psychiatric disorders and the irritable bowel syndromeJ H Rubenstein
Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, MI 48109 0362, USA
Aliment Pharmacol Ther 26:443-52. 2007..We hypothesized that such PPI non-responders have heightened oesophageal sensation, and that oesophageal hypersensitivity is associated with psychiatric features including somatization and anxiety...
Cost utility of screening for Barrett's esophagus with esophageal capsule endoscopy versus conventional upper endoscopyJoel H Rubenstein
Division of Gastroenterology, University of Michigan Medical School, and the Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan 48105, USA
Clin Gastroenterol Hepatol 5:312-8. 2007..Esophageal capsule endoscopy (ECE) has recently been shown to be accurate in detecting Barrett's esophagus. We aimed to compare the cost-effectiveness of screening by ECE with screening by EGD...
Systematic review: the hepatotoxicity of non-steroidal anti-inflammatory drugsJ H Rubenstein
Division of Gastroenterology, University of Michigan Health System, Ann Arbor, MI 48109 0362, USA
Aliment Pharmacol Ther 20:373-80. 2004..Non-steroidal anti-inflammatory drugs have been implicated in reports of liver injury. However, the precise risk of non-steroidal anti-inflammatory drugs for this rare complication is unknown...
The cost-effectiveness of biomarkers for predicting the development of oesophageal adenocarcinomaJ H Rubenstein
University of Michigan Health System, Ann Arbor, MI, USA
Aliment Pharmacol Ther 22:135-46. 2005..The recommended surveillance strategy for oesophageal adenocarcinoma may prevent as few as 50% of cancer deaths. Tissue biomarkers have been proposed to identify high-risk patients...
Relationship between diabetes mellitus and adenocarcinoma of the oesophagus and gastric cardiaJ H Rubenstein
The Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, MI, USA
Aliment Pharmacol Ther 22:267-71. 2005..Obesity is a risk factor for adenocarcinomas of the oesophagus and gastric cardia. Diabetes mellitus might mediate that association...
Defining a clinically significant adverse impact of diagnosing Barrett's esophagusJoel H Rubenstein
Division of Gastroenterology, University of Michigan Health System and Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI 48105, USA
J Clin Gastroenterol 40:109-15. 2006..It is unknown whether the mere diagnosis of Barrett's esophagus (BE) adversely impacts patients' preferences (health-state utility) sufficiently to impair the cost-effectiveness of endoscopic screening for esophageal adenocarcinoma...
The yield of colonoscopy in patients with non-constipated irritable bowel syndrome: results from a prospective, controlled US trialWilliam D Chey
Divison of Gastroenterology, University of Michigan Health System, Ann Arbor, Michigan, USA
Am J Gastroenterol 105:859-65. 2010..This study compared the prevalence of structural colonic lesions in patients with suspected non-constipation-predominant IBS and healthy volunteers. We also determined the yield of rectosigmoid biopsies in patients with suspected IBS...
A pilot study of the association of low plasma adiponectin and Barrett's esophagusJoel H Rubenstein
Ann Arbor Veterans Affairs Medical Center, Ann Arbor, MI 48105, USA
Am J Gastroenterol 103:1358-64. 2008..We aimed to estimate the effect of circulating adiponectin on the risk of Barrett's esophagus (BE), an accepted precursor of EAC, controlling for GERD symptoms and other potential confounders...
Effect of a prior endoscopy on outcomes of esophageal adenocarcinoma among United States veteransJoel H Rubenstein
Gastroenterology Section, Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan 48105, USA
Gastrointest Endosc 68:849-55. 2008..The efficacy of screening and surveillance EGD for esophageal adenocarcinoma (EAC) is controversial...
Knowledge of hepatocellular carcinoma screening guidelines and clinical practices among gastroenterologistsPratima Sharma
Division of Gastroenterology, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109, USA
Dig Dis Sci 56:569-77. 2011..Our aim was to assess gastroenterologists' knowledge of HCC management guidelines established by the American Association for the Study of Liver Diseases (AASLD) and usual clinical practice...
Evidence based medicine (EBM) in practice: applying results of cost-effectiveness analysesJoel H Rubenstein
Division of Gastroenterology, University of Michigan School of Medicine, and Ann Arbor Veterans Administration Medical Center, Michigan 48105, USA
Am J Gastroenterol 101:1169-71. 2006
Influence of malpractice history on the practice of screening and surveillance for Barrett's esophagusJoel H Rubenstein
Ann Arbor Veterans Affairs Medical Center, Ann Arbor, Michigan 48105, USA
Am J Gastroenterol 103:842-9. 2008..We hypothesized that financial incentives and concerns over malpractice litigation influence gastroenterologists' usual practices regarding screening and surveillance...
Meta-analyses of the effect of symptoms of gastroesophageal reflux on the risk of Barrett's esophagusJustin B Taylor
Michigan Institute for Clinical and Health Research, Ann Arbor, Michigan, USA
Am J Gastroenterol 105:1729, 1730-7; quiz 1738. 2010..We hypothesized that studies of higher-quality design show weaker associations of GERD with BE, and that GERD is only weakly associated with short-segment Barrett's esophagus (SSBE)...
The impact of rotating shift work on the prevalence of irritable bowel syndrome in nursesBorko Nojkov
Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan 48105, USA
Am J Gastroenterol 105:842-7. 2010....
Factors associated with esophageal stricture formation after endoscopic mucosal resection for neoplastic Barrett's esophagusJason J Lewis
University of Michigan Health System, Ann Arbor Michigan, USA
Gastrointest Endosc 74:753-60. 2011..EMR for early neoplastic Barrett's esophagus is gaining favor over esophagectomy. Esophageal stricture development has been reported as a common complication of EMR, photodynamic therapy, and combination endoscopic therapy...
Barrett's esophagus: prevalence-incidence and etiology-originsGary W Falk
Department of Medicine, Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Ann N Y Acad Sci 1232:1-17. 2011..Gastroesophageal reflux disease may be considered an immune-mediated disease starting at the submucosal layer; the cytokine profile of the mucosal immune response may explain the different outcome of gastroesophageal reflux...
A cost-utility analysis of secondary prophylaxis for variceal hemorrhageJoel H Rubenstein
Division of Gastroenterology, University of Michigan Health System, Ann Arbor, Michigan 48109-0362, USA
Am J Gastroenterol 99:1274-88. 2004..The redundancy of combination band ligation plus medical therapy can improve outcomes, particularly in the setting of poor patient adherence...
The influence of co-morbid IBS and psychological distress on outcomes and quality of life following PPI therapy in patients with gastro-oesophageal reflux diseaseB Nojkov
Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, MI, USA
Aliment Pharmacol Ther 27:473-82. 2008..A subset of patients with gastro-oesophageal reflux disease (GERD) does not achieve complete symptom resolution with proton pump inhibitor (PPI) therapy. The factors which affect response to PPI therapy in GERD patients remain unclear...
Radiation doses to ERCP patients are significantly lower with experienced endoscopistsJennifer E Jorgensen
Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan 48109 5362, USA
Gastrointest Endosc 72:58-65. 2010..Patients undergoing ERCP receive nontrivial doses of radiation, which may increase their risk of developing cancer, especially young patients. Radiation doses to patients during ERCP correlate closely with fluoroscopy time...
Helicobacter pylori DNA decreases pro-inflammatory cytokine production by dendritic cells and attenuates dextran sodium sulphate-induced colitisJay Luther
Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109 5682, USA
Gut 60:1479-86. 2011..However, the mechanism for the observed inverse association between H pylori and IBD has not been described...
Dysphagia drives doctors to diagnose a disease: pitfalls in interpreting observational studiesJoel H Rubenstein
Gastrointest Endosc 61:809-11. 2005
Infliximab decreases resource use among patients with Crohn's diseaseJoel H Rubenstein
University of Chicago Hospitals, Chicago, Illinois 60637, U.S.A
J Clin Gastroenterol 35:151-6. 2002..This decrease in use of healthcare resources raises the potential of overall cost savings in CD patients receiving this drug...
Research Grants
- The Epidemiology of Adipokines in Barrett's EsophagusJoel Rubenstein; Fiscal Year: 2007..If so, measurement of these substances may be useful in a screening program. ..
