M Rubenfire

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. doi request reprint Lipoprotein (a): perspectives from a lipid-referral program
    Melvyn Rubenfire
    Division of Cardiovascular Medicine, University of Michigan, 24 Frank Lloyd Wright Drive, PO Box 322, Ann Arbor, MI 48188, USA
    J Clin Lipidol 6:66-73. 2012
  2. ncbi request reprint How to manage primary pulmonary hypertension. Giving hope to patients with a life-threatening illness
    M J Ricciardi
    Division of Cardiology, Northwestern University Medical School, Chicago, USA
    Postgrad Med 105:45-8, 51-6. 1999
  3. ncbi request reprint Carotid artery reactivity to isometric hand grip exercise identifies persons at risk and with coronary disease
    Melvyn Rubenfire
    Division of Cardiology, Department of Internal Medicine, University of Michigan Health System, P O Box 363, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48106 0363, USA
    Atherosclerosis 160:241-8. 2002
  4. ncbi request reprint Anaerobic dental flora and the acute coronary syndrome
    Melvyn Rubenfire
    Division of Cardiovascular Medicine and Department of Internal Medicine, School of Dentistry, Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48106 0363, USA
    Coron Artery Dis 18:111-6. 2007
  5. ncbi request reprint Transition from IV epoprostenol to subcutaneous treprostinil in pulmonary arterial hypertension: a controlled trial
    Melvyn Rubenfire
    University of Michigan, 24 Frank Lloyd Wright Dr, Ann Arbor, MI 48106 0363, USA
    Chest 132:757-63. 2007
  6. ncbi request reprint Pulmonary hypertension in the critical care setting: classification, pathophysiology, diagnosis, and management
    Melvyn Rubenfire
    Division of Cardiovascular Medicine and Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48106 0363, USA
    Crit Care Clin 23:801-34, vi-vii. 2007
  7. doi request reprint Evaluating health-related quality of life, work ability, and disability in pulmonary arterial hypertension: an unmet need
    Melvyn Rubenfire
    Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA
    Chest 136:597-603. 2009
  8. doi request reprint Treating mixed hyperlipidemia and the atherogenic lipid phenotype for prevention of cardiovascular events
    Melvyn Rubenfire
    Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Mich 48106, USA
    Am J Med 123:892-8. 2010
  9. ncbi request reprint Carotid artery vasoreactivity in response to sympathetic stress correlates with coronary disease risk and is independent of wall thickness
    M Rubenfire
    Department of Internal Medicine, University of Michigan, Ann Arbor, USA
    J Am Coll Cardiol 36:2192-7. 2000
  10. doi request reprint The metabolic fitness program: lifestyle modification for the metabolic syndrome using the resources of cardiac rehabilitation
    Melvyn Rubenfire
    Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
    J Cardiopulm Rehabil Prev 31:282-9. 2011

Detail Information

Publications46

  1. doi request reprint Lipoprotein (a): perspectives from a lipid-referral program
    Melvyn Rubenfire
    Division of Cardiovascular Medicine, University of Michigan, 24 Frank Lloyd Wright Drive, PO Box 322, Ann Arbor, MI 48188, USA
    J Clin Lipidol 6:66-73. 2012
    ..Lipoprotein (a) [Lp(a)] has a strong association with coronary disease (CHD). We evaluated the implications of implementing a niacin strategy in persons above low risk by the Framingham risk score (FRS)...
  2. ncbi request reprint How to manage primary pulmonary hypertension. Giving hope to patients with a life-threatening illness
    M J Ricciardi
    Division of Cardiology, Northwestern University Medical School, Chicago, USA
    Postgrad Med 105:45-8, 51-6. 1999
    ..It has markedly improved quality of life and extended survival in patients with the condition, and it has changed the physician's role from providing emotional support to dying patients to providing management of a chronic disease...
  3. ncbi request reprint Carotid artery reactivity to isometric hand grip exercise identifies persons at risk and with coronary disease
    Melvyn Rubenfire
    Division of Cardiology, Department of Internal Medicine, University of Michigan Health System, P O Box 363, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48106 0363, USA
    Atherosclerosis 160:241-8. 2002
    ..We designed a study to determine the CA diameter (CA(d)) response to exercise (IHG), whether the response is influenced by coronary risk, and compare it with the BAO(cclR) method...
  4. ncbi request reprint Anaerobic dental flora and the acute coronary syndrome
    Melvyn Rubenfire
    Division of Cardiovascular Medicine and Department of Internal Medicine, School of Dentistry, Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan 48106 0363, USA
    Coron Artery Dis 18:111-6. 2007
    ..Evidence exists that coronary heart disease is influenced by anaerobic bacterial flora and gingival inflammation. We assessed the association of periodontal bacteria, coronary artery disease, and acute coronary events...
  5. ncbi request reprint Transition from IV epoprostenol to subcutaneous treprostinil in pulmonary arterial hypertension: a controlled trial
    Melvyn Rubenfire
    University of Michigan, 24 Frank Lloyd Wright Dr, Ann Arbor, MI 48106 0363, USA
    Chest 132:757-63. 2007
    ..We determined the relative efficacy of subcutaneous (SC) treprostinil in stable World Health Organization class II and III patients transitioned from IV epoprostenol...
  6. ncbi request reprint Pulmonary hypertension in the critical care setting: classification, pathophysiology, diagnosis, and management
    Melvyn Rubenfire
    Division of Cardiovascular Medicine and Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48106 0363, USA
    Crit Care Clin 23:801-34, vi-vii. 2007
    ..We review the physiology, definitions, classification, pathogenesis, diagnostic tools, and algorithms for diagnosis and specific treatments for the various causes of PH as seen in the critical care setting...
  7. doi request reprint Evaluating health-related quality of life, work ability, and disability in pulmonary arterial hypertension: an unmet need
    Melvyn Rubenfire
    Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA
    Chest 136:597-603. 2009
    ..We also discuss the impact of PAH on work ability and the need for provisions to address medical disability status and Social Security benefit status...
  8. doi request reprint Treating mixed hyperlipidemia and the atherogenic lipid phenotype for prevention of cardiovascular events
    Melvyn Rubenfire
    Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Mich 48106, USA
    Am J Med 123:892-8. 2010
    ....
  9. ncbi request reprint Carotid artery vasoreactivity in response to sympathetic stress correlates with coronary disease risk and is independent of wall thickness
    M Rubenfire
    Department of Internal Medicine, University of Michigan, Ann Arbor, USA
    J Am Coll Cardiol 36:2192-7. 2000
    ..We designed a study to determine the carotid artery (CA) response to sympathetic activity and to determine whether the response correlates with coronary risk and is independent of wall thickness (IMT)...
  10. doi request reprint The metabolic fitness program: lifestyle modification for the metabolic syndrome using the resources of cardiac rehabilitation
    Melvyn Rubenfire
    Division of Cardiovascular Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
    J Cardiopulm Rehabil Prev 31:282-9. 2011
    ..To describe and assess the effectiveness of a lifestyle intervention program (Met Fit) designed to treat the metabolic syndrome (MetSyn) in a cardiac rehabilitation setting...
  11. ncbi request reprint Usefulness of brachial artery reactivity to isometric handgrip exercise in identifying patients at risk and with coronary artery disease
    M Rubenfire
    Department of Internal Medicine, University of Michigan, Ann Arbor, USA
    Am J Cardiol 86:1161-5. 2000
    ..5% for IHG vs 71.6% for occlusion and release, p = 0.086). BA response to IHG may be useful for identifying risk factors, patients at risk and with preclinical CAD, and the assessment of treatment strategies...
  12. ncbi request reprint Safety and compliance with once-daily niacin extended-release/lovastatin as initial therapy in the Impact of Medical Subspecialty on Patient Compliance to Treatment (IMPACT) study
    Melvyn Rubenfire
    Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, 48109 0363, USA
    Am J Cardiol 94:306-11. 2004
    ..Niacin extended-release/lovastatin 1,000/40 mg, dosed as initial therapy, was associated with good compliance and safety and had very low incidences of increased liver and muscle enzymes...
  13. ncbi request reprint Oxygen desaturation on the six-minute walk test and mortality in untreated primary pulmonary hypertension
    G Paciocco
    Dept of Internal Medicine, University of Michigan, Ann Arbor, USA
    Eur Respir J 17:647-52. 2001
    ..The six-minute walk distance and exercise oxygen saturation may be helpful in selecting patients with primary pulmonary hypertension for whom transplant listing is appropriate...
  14. ncbi request reprint Association between self-reported physical activity and vascular reactivity in postmenopausal women
    R McKechnie
    Department of Internal Medicine, Division of Cardiology, The University of Michigan Medical Center, Ann Arbor, MI, USA
    Atherosclerosis 159:483-90. 2001
    ....
  15. ncbi request reprint Life-threatening acute and chronic thromboembolic pulmonary hypertension and subclavian vein thrombosis
    Mark A Meier
    Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
    Clin Cardiol 29:103-6. 2006
    ..We then review the mechanism, clinical presentation, diagnosis, and available therapeutic modalities...
  16. ncbi request reprint Usefulness of visceral obesity (waist/hip ratio) in predicting vascular endothelial function in healthy overweight adults
    R D Brook
    Division of Hypertension, University of Michigan, Ann Arbor, Michigan, USA
    Am J Cardiol 88:1264-9. 2001
    ....
  17. ncbi request reprint Abnormal brachial artery flow-mediated vasodilation in young adults with major depression
    S Rajagopalan
    Department of Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, USA
    Am J Cardiol 88:196-8, A7. 2001
    ..Further studies are needed to define the mechanisms that underlie these observations...
  18. ncbi request reprint Potential clinical and economic effects of homocyst(e)ine lowering
    B K Nallamothu
    Division of General Medicine, University of Michigan Medical Center, 3116 Taubman Center, Ann Arbor, MI 48109 0376, USA
    Arch Intern Med 160:3406-12. 2000
    ..However, the benefits expected from lowering homocyst(e)ine levels with folic acid and vitamin B(12) supplementation have yet to be demonstrated in clinical trials...
  19. ncbi request reprint Effect of statin use in patients with acute coronary syndromes and a serum low-density lipoprotein<or=80 mg/dl
    Thomas T Tsai
    Department of Internal Medicine, Division of Cardiology, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Am J Cardiol 96:1491-3. 2005
    ..0% vs 9.5%, p=0.005). These results suggest that patients who have an acute coronary syndrome and a low-density lipoprotein cholesterol level<or=80 mg/dl in the absence of statin therapy may benefit from such therapy at discharge...
  20. doi request reprint Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial
    Vallerie V McLaughlin
    University of Michigan Health System, CVC Cardiovascular Medicine, Ann Arbor, Michigan 48109 5853, USA
    J Am Coll Cardiol 55:1915-22. 2010
    ..This study assessed the efficacy and safety of inhaled treprostinil in pulmonary arterial hypertension (PAH) patients receiving therapy with either bosentan or sildenafil...
  21. pmc Perceived quality of care and lifestyle counseling among patients with heart disease
    Elizabeth A Jackson
    Department of Internal Medicine, University of Michigan Health System, Ann Arbor, USA
    Clin Cardiol 33:765-9. 2010
    ..To examine patients' perceived quality of care and reported receipt of information on diet and exercise related to cardiovascular disease prevention...
  22. ncbi request reprint A negative carotid plaque area test is superior to other noninvasive atherosclerosis studies for reducing the likelihood of having underlying significant coronary artery disease
    Robert D Brook
    Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA
    Arterioscler Thromb Vasc Biol 26:656-62. 2006
    ..Although each test may enhance risk stratification, their comparative abilities to screen for underlying coronary stenoses in individual patients is less established...
  23. doi request reprint The lipid management nutrition outcomes project: perspectives from a national experience in protocol implementation and nutrition outcomes tracking
    Katherine S Rhodes
    Division of Cardiovascular Medicine, Preventive Cardiology, University of Michigan Health System, Ann Arbor, MI 48106 0363, USA
    J Am Diet Assoc 108:332-9. 2008
    ..7+/-16.5 weeks with 3.0+/-1.4 RD visits. The Lipid Management Nutrition Outcomes Project highlights frustrations and values of outcomes monitoring in actual practice and identifies areas for practice advancement...
  24. ncbi request reprint Behavioral medicine: the challenge of integrating psychological and behavioral approaches into primary care
    Peter C Trask
    Behavioral Medicine Program, University of Michigan, Ann Arbor 48108 0757, USA
    Eff Clin Pract 5:75-83. 2002
  25. ncbi request reprint Usefulness of low-density lipoprotein particle size measurement in cardiovascular disease prevention
    Robert D Brook
    Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA
    Clin Cardiol 28:534-7. 2005
    ....
  26. doi request reprint The effect of St John's Wort on the pharmacodynamic response of clopidogrel in hyporesponsive volunteers and patients: increased platelet inhibition by enhancement of CYP3A4 metabolic activity
    Wei C Lau
    Cardiovascular Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109 5861, USA
    J Cardiovasc Pharmacol 57:86-93. 2011
    ..0002) and increased platelet inhibition (23% ± 11% vs. 41% ± 16%, P = 0.002). SJW may be a future therapeutic option to increase CYP metabolic activity and antiplatelet effect of clopidogrel in hyporesponders...
  27. ncbi request reprint Unexplained exertional limitation: characterization of patients with a mitochondrial myopathy
    K R Flaherty
    Dyspnea and Pulmonary Hypertension Clinics, University of Michigan Health System, Ann Arbor, Michigan, USA
    Am J Respir Crit Care Med 164:425-32. 2001
    ..We conclude that mitochondrial myopathies are more prevalent than previously reported. The characteristic physiological profile may be useful in the diagnostic evaluation of mitochondrial myopathy...
  28. ncbi request reprint Frequency of negative coronary arteriographic findings in patients with chest pain is related to community practice patterns
    Peter M Farrehi
    Department of Internal Medicine, University of Michigan, Ann Arbor, USA
    Am J Manag Care 8:643-8. 2002
    ..Cardiology self-referral and personal gain does not seem to be a major factor in selection of patients for invasive studies...
  29. doi request reprint Potential effect of an apoprotein B-based algorithm on management of new patients with hypertriglyceridemia referred to a specialty lipid clinic
    Robert D Brook
    Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA
    Clin Cardiol 32:251-5. 2009
    ..In patients with hypertriglyceridemia, non-high density lipoprotein cholesterol (nonHDL-C) is a targeted goal. However, apoprotein B100 (apoB) may be superior in predicting cardiovascular risk so we assessed the utility of an apoB-based...
  30. ncbi request reprint The prognostic role of the ECG in primary pulmonary hypertension
    Eduardo Bossone
    Division of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48106 0363, USA
    Chest 121:513-8. 2002
    ..The aims of the present study were to examine whether ECG features in patients with PPH are associated with a decrease in survival, and to determine the value of the ECG in risk stratification...
  31. ncbi request reprint Electron-beam computed tomography in the diagnosis of coronary artery disease: a meta-analysis
    B K Nallamothu
    B1F245, Division of General Medicine, University Hospital, Ann Arbor, MI 48109 0022, USA
    Arch Intern Med 161:833-8. 2001
    ..Before its clinical use is justified, however, the overall accuracy of EBCT must be better defined...
  32. ncbi request reprint Utility of C-reactive protein measurement in risk stratification during primary cardiovascular disease prevention
    Robert L Bard
    Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA
    Am J Cardiol 95:1378-9. 2005
    ..Because hs-CRP evaluation significantly altered the cardiovascular risk strata of most intermediate-risk patients, it may therefore be a useful test during primary cardiovascular disease prevention...
  33. ncbi request reprint Lung and heart-lung transplant practice patterns in pulmonary hypertension centers
    E J Pielsticker
    Department of Internal Medicine, Division of Cardiology, University of Michigan, Ann Arbor 48106-0363, USA
    J Heart Lung Transplant 20:1297-304. 2001
    ..CONCLUSIONS: Physicians and patients should be aware of the considerable variability in practice patterns for transplantation in pulmonary hypertension, despite published guidelines...
  34. ncbi request reprint Balloon atrial septostomy in end-stage pulmonary hypertension guided by a novel intracardiac echocardiographic transducer
    M Moscucci
    Division of Cardiology, Department of Medicine, University of Michigan Health System, Ann Arbor, Michigan 48108, USA
    Catheter Cardiovasc Interv 52:530-4. 2001
    ..5--10 MHz transducer with spectral and color-flow Doppler capabilities was used to assist a balloon atrial septostomy and to obtain hemodynamic data in a patient with end-stage pulmonary hypertension...
  35. ncbi request reprint Effect of carotid atherosclerosis screening on risk stratification during primary cardiovascular disease prevention
    Robert L Bard
    Division of Cardiovascular Medicine, Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA
    Am J Cardiol 93:1030-2. 2004
    ..These tests adjust the risk strata of >/=63% of patients deemed as having intermediate risk by Framingham scores...
  36. ncbi request reprint Altered cutaneous microvascular responses to reactive hyperaemia in coronary artery disease: a comparative study with conduit vessel responses
    Qurratul Aine Shamim-Uzzaman
    Department of Internal Medicine, and Section of Vascular Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48109 0273, USA
    Clin Sci (Lond) 103:267-73. 2002
    ..However, a time to peak response of >10 s as measured by laser Doppler imaging offers superior specificity for the diagnosis of CAD compared with brachial FMD...
  37. ncbi request reprint Antioxidant nutrient supplementation and brachial reactivity in patients with coronary artery disease
    Ronald McKechnie
    Department of Internal Medicine, Division of Cardiology, University of Michigan Medical Center, Ann Arbor, MI, USA
    J Lab Clin Med 139:133-9. 2002
    ..These data should be confirmed in larger-scale trials and examined in studies evaluating individual dietary antioxidant supplementation...
  38. ncbi request reprint Cardiovascular risk factors in ethnic minority women aged < or =30 years
    Latha Palaniappan
    Division of Cardiology, Department of Internal Medicine, Ann Arbor, Michigan, USA
    Am J Cardiol 89:524-9. 2002
    ..The tendency toward peripheral insulin insensitivity and increased body fat in this age group of African-American women suggests diet and exercise may reduce the risk of subsequent CHD...
  39. ncbi request reprint The impact of time and day on the presentation of acute coronary syndromes
    Troy LaBounty
    Michigan Cardiovascular Outcomes Research and Reporting Program, Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical Center, University of Michigan, Ann Arbor, Michigan 48106 0363, USA
    Clin Cardiol 29:542-6. 2006
    ..The frequency of acute myocardial infarction (AMI) peaks on Mondays and in the mornings. However, the distribution of the types of acute coronary syndromes (ACS), including unstable angina (UA), has not been systematically evaluated...
  40. ncbi request reprint Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial
    Gerald Simonneau
    Service de Pneumologie, Hopital Antoine Beclere, Universite Paris Sud, Clamart, France
    Ann Intern Med 149:521-30. 2008
    ..Oral sildenafil and intravenous epoprostenol have independently been shown to be effective in patients with pulmonary arterial hypertension...
  41. doi request reprint Latent pulmonary hypertension: looking beyond the scene
    Eduardo Bossone
    Chest 134:469-70. 2008
  42. ncbi request reprint The interpretation of the electrocardiogram in patients with pulmonary hypertension: the need for clinical correlation
    Eduardo Bossone
    National Research Council, Lecce, and Institute of Respiratory Disease, University of Milan, IRCCS Ospedale Maggiore, Milan, Italy
    Ital Heart J 4:850-4. 2003
    ..The aim of the study was to determine the importance of clinical information in providing an accurately edited electrocardiographic system...
  43. ncbi request reprint Psychosocial aspects of pulmonary hypertension: a review
    John M Wryobeck
    University of Toledo Health Science Campus, Department of Psychiatry, Toledo, OH 43614, USA
    Psychosomatics 48:467-75. 2007
    ....
  44. ncbi request reprint Outcome after cardiopulmonary resuscitation in patients with pulmonary arterial hypertension
    Marius M Hoeper
    Dept of Respiratory Medicine, Hannover Medical School, 30623 Hannover, Germany
    Am J Respir Crit Care Med 165:341-4. 2002
    ..Our data indicate that CPR for circulatory arrest in patients with PAH is rarely successful unless the cause of the cardiopulmonary decompensation can be corrected...
  45. ncbi request reprint Cardiovascular response to exercise in elite ice hockey players
    Eduardo Bossone
    Institute of Respiratory Diseases, University of Milan, IRCCS Ospedale Maggiore, Milan, Italy
    Can J Cardiol 20:893-7. 2004
    ..High-performance ice hockey requires unique strength and endurance, which are facilitated by training...
  46. doi request reprint Defining appropriate outcome measures in pulmonary arterial hypertension related to systemic sclerosis: a Delphi consensus study with cluster analysis
    Oliver Distler
    University Hospital Zurich, Zurich, Switzerland
    Arthritis Rheum 59:867-75. 2008
    ..The aim of the present study was to establish an expert consensus regarding which outcome measures are most appropriate for clinical trials in PAH-SSc...