Peter P Roy-Byrne

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Effects of pain and prescription opioid use on outcomes in a collaborative care intervention for anxiety
    Peter Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98104, USA
    Clin J Pain 29:800-6. 2013
  2. pmc Self-reported alcohol and drug use six months after brief intervention: do changes in reported use vary by mental-health status?
    Antoinette Krupski
    Department of Psychiatry and Behavioral Sciences, Center for Healthcare Improvement for Addictions, Mental Illness and Medically Vulnerable Populations CHAMMP, University of Washington at Harborview Medical Center, Seattle, WA, USA
    Addict Sci Clin Pract 7:24. 2012
  3. pmc Testing the effects of brief intervention in primary care for problem drug use in a randomized controlled trial: rationale, design, and methods
    Antoinette Krupski
    Department of Psychiatry and Behavioral Sciences, University of Washington at Harborview Medical Center, Seattle, WA, USA
    Addict Sci Clin Pract 7:27. 2012
  4. doi request reprint Collaborative care at the crossroads
    Peter Roy-Byrne
    Peter Roy Byrne, MD, University of Washington School of Medicine, At Harborview Medical Center, Box 35 9911, 325 9th Avenue, Seattle, Washington, USA Email
    Br J Psychiatry 203:86-7. 2013
  5. pmc Implementation of the CALM intervention for anxiety disorders: a qualitative study
    Geoffrey M Curran
    Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Implement Sci 7:1-11. 2012
  6. ncbi request reprint Paroxetine response and tolerability among ethnic minority patients with mood or anxiety disorders: a pooled analysis
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington at Harborview Medical Center, Seattle 98104, USA
    J Clin Psychiatry 66:1228-33. 2005
  7. ncbi request reprint Medical illness and response to treatment in primary care panic disorder
    Peter Roy-Byrne
    Department of Psychiatry and Behavioral Science, University of Washington School of Medicine at Harborview Medical Center, WA 98104, USA
    Gen Hosp Psychiatry 27:237-43. 2005
  8. ncbi request reprint Understanding and treating panic disorder in the primary care setting
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Medical Center, Seattle, USA
    J Clin Psychiatry 66:16-22. 2005
  9. ncbi request reprint Use of herbal medicine in primary care patients with mood and anxiety disorders
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, Harborview Medical Center, University of Washington School of Medicine, Box 359911, 325 9th Ave, Seattle, WA 98104, USA
    Psychosomatics 46:117-22. 2005
  10. ncbi request reprint The GABA-benzodiazepine receptor complex: structure, function, and role in anxiety
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98104, USA
    J Clin Psychiatry 66:14-20. 2005

Research Grants

Detail Information

Publications94

  1. pmc Effects of pain and prescription opioid use on outcomes in a collaborative care intervention for anxiety
    Peter Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98104, USA
    Clin J Pain 29:800-6. 2013
    ....
  2. pmc Self-reported alcohol and drug use six months after brief intervention: do changes in reported use vary by mental-health status?
    Antoinette Krupski
    Department of Psychiatry and Behavioral Sciences, Center for Healthcare Improvement for Addictions, Mental Illness and Medically Vulnerable Populations CHAMMP, University of Washington at Harborview Medical Center, Seattle, WA, USA
    Addict Sci Clin Pract 7:24. 2012
    ..The goal of this study was to explore differences in self-reported alcohol and/or drug use in patients with and without mental illness diagnoses six months after receiving BI in a hospital emergency department (ED)...
  3. pmc Testing the effects of brief intervention in primary care for problem drug use in a randomized controlled trial: rationale, design, and methods
    Antoinette Krupski
    Department of Psychiatry and Behavioral Sciences, University of Washington at Harborview Medical Center, Seattle, WA, USA
    Addict Sci Clin Pract 7:27. 2012
    ..This article describes the design of a study testing the impact of SBIRT on individuals with drug problems, its contributions to the existing literature, and its potential to inform drug policy...
  4. doi request reprint Collaborative care at the crossroads
    Peter Roy-Byrne
    Peter Roy Byrne, MD, University of Washington School of Medicine, At Harborview Medical Center, Box 35 9911, 325 9th Avenue, Seattle, Washington, USA Email
    Br J Psychiatry 203:86-7. 2013
    ..The upcoming reorganisation of US healthcare will rely heavily on adaptations of this model to improve its uptake and cost-effectiveness. ..
  5. pmc Implementation of the CALM intervention for anxiety disorders: a qualitative study
    Geoffrey M Curran
    Department of Psychiatry, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Implement Sci 7:1-11. 2012
    ..Key research questions were as follows: (1) What were the facilitators/barriers to implementing CALM? (2) What were the facilitators/barriers to sustaining CALM after the study was completed?..
  6. ncbi request reprint Paroxetine response and tolerability among ethnic minority patients with mood or anxiety disorders: a pooled analysis
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington at Harborview Medical Center, Seattle 98104, USA
    J Clin Psychiatry 66:1228-33. 2005
    ....
  7. ncbi request reprint Medical illness and response to treatment in primary care panic disorder
    Peter Roy-Byrne
    Department of Psychiatry and Behavioral Science, University of Washington School of Medicine at Harborview Medical Center, WA 98104, USA
    Gen Hosp Psychiatry 27:237-43. 2005
    ..Although studies have suggested that comorbid medical illness can affect the outcome of patients with depression, little is known about whether medical illness comorbidity affects treatment outcome in patients with anxiety...
  8. ncbi request reprint Understanding and treating panic disorder in the primary care setting
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Medical Center, Seattle, USA
    J Clin Psychiatry 66:16-22. 2005
    ....
  9. ncbi request reprint Use of herbal medicine in primary care patients with mood and anxiety disorders
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, Harborview Medical Center, University of Washington School of Medicine, Box 359911, 325 9th Ave, Seattle, WA 98104, USA
    Psychosomatics 46:117-22. 2005
    ..Use was not associated with receipt of pharmacotherapy or psychotherapy for anxiety or depression...
  10. ncbi request reprint The GABA-benzodiazepine receptor complex: structure, function, and role in anxiety
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98104, USA
    J Clin Psychiatry 66:14-20. 2005
    ..Finally, chronic treatment with benzodiazepines causes the development of tolerance, which may be associated with molecular changes and a pharmacologic response profile similar to that observed in pathologically anxious humans...
  11. pmc Brief intervention for anxiety in primary care patients
    Peter Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Center for Healthcare Improvement for Addictions, Mental Illness and Medically Vulnerable Populations, Seattle, USA
    J Am Board Fam Med 22:175-86. 2009
    ....
  12. ncbi request reprint Poverty and response to treatment among panic disorder patients in primary care
    Peter Roy-Byrne
    Department of Psychiatry and Behavioral Science, University of Washington School of Medicine at Harborview Medical Center, 326 9th Ave, Seattle, WA 98104, USA
    Am J Psychiatry 163:1419-25. 2006
    ....
  13. pmc Is the association between posttraumatic stress disorder symptoms and poor health due to a common familial or genetic factor?
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington at Harborview Medical Center, Seattle, WA 98104, USA
    Gen Hosp Psychiatry 28:408-13. 2006
    ..The objective of this study was to identify genetic, familial and environmental contributions to the association between posttraumatic stress disorder (PTSD) symptoms and poor health...
  14. ncbi request reprint Panic disorder
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine at Harborview Medical Center, Seattle, WA 98104 2499, USA
    Lancet 368:1023-32. 2006
    ..The adaptation and dissemination of these treatments to the frontlines of medical-care delivery should be urgent goals for the public-health community...
  15. doi request reprint Anxiety disorders and comorbid medical illness
    Peter P Roy-Byrne
    University of Washington School of Medicine, Seattle, WA 98195, USA
    Gen Hosp Psychiatry 30:208-25. 2008
    ..To provide an overview of the role of anxiety disorders in medical illness...
  16. doi request reprint Low socioeconomic status and mental health care use among respondents with anxiety and depression in the NCS-R
    Peter P Roy-Byrne
    Department of Psychiatry, Harborview Medical Center, University of Washington School of Medicine, 325 9th Ave, Box 359911, Seattle, WA 98104 2499, USA
    Psychiatr Serv 60:1190-7. 2009
    ....
  17. pmc Delivery of evidence-based treatment for multiple anxiety disorders in primary care: a randomized controlled trial
    Peter Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine and Harborview Center for Healthcare Improvement for Addictions, Mental Illness, and Medically Vulnerable Populations, Seattle, Washington 98104, USA
    JAMA 303:1921-8. 2010
    ..Although such advances have been made for depression, little work has been performed for anxiety disorders...
  18. ncbi request reprint Risk factors and outcome in ambulatory assault victims presenting to the acute emergency department setting: implications for secondary prevention studies in PTSD
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, Harborview Medical Center, University of Washington, Seattle, Washington 98104 2499, USA
    Depress Anxiety 19:77-84. 2004
    ....
  19. ncbi request reprint Unemployment and emergency room visits predict poor treatment outcome in primary care panic disorder
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Science, University of Washington, Seattle, USA
    J Clin Psychiatry 64:383-9. 2003
    ....
  20. ncbi request reprint Reduced benzodiazepine sensitivity in patients with panic disorder: comparison with patients with obsessive-compulsive disorder and normal subjects
    P Roy-Byrne
    Department of Psychiatry, Tufts University, Boston, USA
    Am J Psychiatry 153:1444-9. 1996
    ....
  21. ncbi request reprint Cardiovascular and catecholamine response to orthostasis in panic and obsessive-compulsive disorder and normal controls: effects of anxiety and novelty
    P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Medical Center, Seattle 98104, USA
    Depress Anxiety 6:159-64. 1997
    ..Failure to control for the effects of both anxiety and novelty, which contribute to subjects' response to orthostatic challenge in control patients, could possibly account for this...
  22. ncbi request reprint Nefazodone treatment of major depression in alcohol-dependent patients: a double-blind, placebo-controlled trial
    P P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences at Harborview Medical Center, Seattle, Washington 98104, USA
    J Clin Psychopharmacol 20:129-36. 2000
    ..Nefazodone treatment was superior to placebo in alleviating depression in these patients but did not add any advantage over the psychoeducational group in terms of drinking outcomes...
  23. ncbi request reprint A randomized effectiveness trial of collaborative care for patients with panic disorder in primary care
    P P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, Harborview Medical Center, 325 9th Ave, Box 359911, Seattle, WA 98104, USA
    Arch Gen Psychiatry 58:869-76. 2001
    ..This study sought to test the clinical effectiveness of PD pharmacotherapy embedded in a disease management framework of "collaborative care" (CC)...
  24. ncbi request reprint Primary care perspectives on generalized anxiety disorder
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine and Harborview Medical Center, Seattle, WA 98104, USA
    J Clin Psychiatry 65:20-6. 2004
    ..Providing efficacious treatment to primary care for GAD will require improving knowledge of providers and increasing patient engagement...
  25. ncbi request reprint Moving treatment research from clinical trials to the real world
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington at Harborview Medical Center, Seattle 98014, USA
    Psychiatr Serv 54:327-32. 2003
    ....
  26. ncbi request reprint Panic disorder in public sector primary care: clinical characteristics and illness severity compared with "mainstream" primary care panic disorder
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington 98104 2499, USA
    Depress Anxiety 17:51-7. 2003
    ....
  27. ncbi request reprint Quality of care for primary care patients with anxiety disorders
    Murray B Stein
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0985, USA
    Am J Psychiatry 161:2230-7. 2004
    ..This study evaluated quality of care for primary care patients with anxiety disorders in university-affiliated outpatient clinics in Los Angeles, San Diego, and Seattle...
  28. pmc Predictors of clinical improvement in a randomized effectiveness trial for primary care patients with panic disorder
    Denise A Chavira
    Department of Psychiatry, University of California, San Diego, CA 92037, USA
    J Nerv Ment Dis 197:715-21. 2009
    ..A greater understanding of these predictors may help clinicians identify who is at greatest risk for persistent panic-related symptoms and to plan the intensity of interventions accordingly...
  29. ncbi request reprint Functional impact and health utility of anxiety disorders in primary care outpatients
    Murray B Stein
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093 0985, USA
    Med Care 43:1164-70. 2005
    ..The objective of this study was to examine the relative impact of anxiety disorders and major depression on functional status and health-related quality of life of primary care outpatients...
  30. pmc Quality of and patient satisfaction with primary health care for anxiety disorders
    Murray B Stein
    Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0855, USA
    J Clin Psychiatry 72:970-6. 2011
    ..Most patients with anxiety disorders receive their care from primary care practitioners (PCPs). The purpose of this study was to evaluate quality of and patient satisfaction with primary health care for anxiety disorders...
  31. ncbi request reprint Beliefs about psychotropic medication and psychotherapy among primary care patients with anxiety disorders
    Amy W Wagner
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine at Harborview Medical Center, Seattle, Washington 98104 2499, USA
    Depress Anxiety 21:99-105. 2005
    ..Treatment adherence may therefore be increased by addressing these beliefs directly...
  32. pmc A randomized effectiveness trial of cognitive-behavioral therapy and medication for primary care panic disorder
    Peter P Roy-Byrne
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine at Harborview Medical Center, Seattle, USA
    Arch Gen Psychiatry 62:290-8. 2005
    ..Although numerous studies have assessed the effectiveness of treatments for depression in primary care, few such studies have been conducted for panic disorder...
  33. ncbi request reprint The impact of comorbid posttraumatic stress disorder on short-term clinical outcome in hospitalized patients with depression
    Paul E Holtzheimer
    Department of Psychiatry and Behavioral Sciences, University of Washington Medical Center, Harborview Medical Center, 325 Ninth Ave, Box 359911, Seattle, WA 98104 2499, USA
    Am J Psychiatry 162:970-6. 2005
    ..The effects of PTSD comorbidity are unclear, especially in patients with severe mental illness. The authors assessed short-term clinical outcome in severely depressed psychiatric inpatients with and without comorbid PTSD...
  34. ncbi request reprint Associations between psychological trauma and physical illness in primary care
    Sonya B Norman
    Department of Psychiatry, University of California, San Diego, CA, USA
    J Trauma Stress 19:461-70. 2006
    ..Awareness of the presence of the physical illnesses examined here may help with the identification and treatment of primary care patients with trauma histories...
  35. ncbi request reprint Methamphetamine users in the psychiatric emergency services: a case-control study
    Jagoda Pasic
    Department of Psychiatry and Behavioral Sciences, Harborview Medical Center, University of Washington School of Medicine, Seattle, Washington 98104, USA
    Am J Drug Alcohol Abuse 33:675-86. 2007
    ..This study shows that hypertension and tachycardia upon arrival to the PES, symptoms of dysphoria and psychosis, past substance use and not having the diagnosis of Schizophrenia are all related to methamphetamine use...
  36. ncbi request reprint In search of mixed anxiety-depressive disorder: a primary care study
    Adrienne J Means-Christensen
    Department of Psychiatry, University of California, San Diego, California, USA
    Depress Anxiety 23:183-9. 2006
    ..These data dispute the need for a mixed anxiety-depression category (beyond mood and anxiety syndromes currently in DSM-IV) in future editions of the DSM...
  37. ncbi request reprint Substance-induced suicidal admissions to an acute psychiatric service: characteristics and outcomes
    Richard K Ries
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98104, USA
    J Subst Abuse Treat 34:72-9. 2008
    ....
  38. ncbi request reprint From bedside to bench: how the epidemiology of clinical practice can inform the secondary prevention of PTSD
    Douglas Zatzick
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, 325 9th Avenue, Seattle, WA 98104 2499, USA
    Psychiatr Serv 57:1726-30. 2006
    ....
  39. ncbi request reprint Using five questions to screen for five common mental disorders in primary care: diagnostic accuracy of the Anxiety and Depression Detector
    Adrienne J Means-Christensen
    Department of Psychiatry, University of California, San Diego, CA 92093 0985, USA
    Gen Hosp Psychiatry 28:108-18. 2006
    ..However, before patients in primary care can be treated, they must be identified. This study set out to validate a very brief screening instrument for identifying primary care patients with anxiety and depression...
  40. ncbi request reprint Geriatric patients improve as much as younger patients from hospitalization on general psychiatric units
    Mark B Snowden
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA
    J Am Geriatr Soc 52:1676-80. 2004
    ..To determine whether geriatric patients aged 65 and older on general adult psychiatric units improve as much as younger patients, over what duration their improvement occurs, and their risk of readmission...
  41. ncbi request reprint Novel treatment approaches for refractory anxiety disorders
    Mark H Pollack
    Harvard Medical School and Center for Anxiety and Traumatic Stress Related Disorders, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Depress Anxiety 25:467-76. 2008
    ..Progress in the development of new treatments has great promise, but will only succeed through a concerted research effort that systematically evaluates potential areas of importance and properly uses scarce resources...
  42. ncbi request reprint Treating minority patients with depression and anxiety: what does the evidence tell us?
    Trevor J Schraufnagel
    Department of Psychiatry and Behavioral Sciences, University of Washington, Harborview Medical Center, Seattle, 98104, USA
    Gen Hosp Psychiatry 28:27-36. 2006
    ..The purpose of this study is to examine the current state of knowledge regarding treating ethnic/racial minority patients with mood and anxiety disorders, emphasizing data-based studies whenever possible...
  43. pmc Validation of a brief measure of anxiety-related severity and impairment: the Overall Anxiety Severity and Impairment Scale (OASIS)
    Laura Campbell-Sills
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0603, USA
    J Affect Disord 112:92-101. 2009
    ..A prior investigation with a nonclinical sample supported the reliability and validity of the OASIS; however, to date it has not been validated for use in clinical samples...
  44. doi request reprint Trajectories of change in anxiety severity and impairment during and after treatment with evidence-based treatment for multiple anxiety disorders in primary care
    Jutta M Joesch
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine and Harborview Center for Healthcare Improvement for Addictions, Mental Illness, and Medically Vulnerable Populations CHAMMP, Seattle, Washington
    Depress Anxiety 30:1099-106. 2013
    ..This study aimed to identify (1) clusters of participants with similar patterns of change in anxiety severity and impairment (trajectory groups); and (2) characteristics that predict trajectory group membership...
  45. doi request reprint Addiction and suicidal behavior in acute psychiatric inpatients
    Richard K Ries
    University of Washington, Seattle, WA, USA
    Compr Psychiatry 50:93-9. 2009
    ..Both degree of substance dependency and degree of substance-induced syndrome were analyzed. In addition, length of stay, involuntary status, and against medical advice discharge status were determined as they related to these variables...
  46. ncbi request reprint The effect of changes in depression on health related quality of life (HRQoL) in HIV infection
    Andrew J Elliott
    University of Washington Department of Psychiatry and Behavior Sciences, Madison Clinic at Harborview Medical Center, Seattle, WA, USA
    Gen Hosp Psychiatry 24:43-7. 2002
    ..HRQoL improved in patients regardless of drug or response group and as a function of being in this trial suggesting that medications may not be required to affect HRQoL outcomes and that disease management aspects of care are important...
  47. ncbi request reprint The selective GABA reuptake inhibitor tiagabine for the treatment of generalized anxiety disorder: results of a placebo-controlled study
    Mark H Pollack
    Anxiety Disorders Program, Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital, Simches Research Building, 185 Cambridge Street, Boston, MA 02114, USA
    J Clin Psychiatry 66:1401-8. 2005
    ..To evaluate the efficacy and tolerability of tiagabine, a selective gamma-aminobutyric acid (GABA) reuptake inhibitor, in adults with generalized anxiety disorder (GAD)...
  48. ncbi request reprint Disclosure of HIV status and sexual orientation independently predicts increased absolute CD4 cell counts over time for psychiatric patients
    Eric D Strachan
    University of Washington School of Medicine, Department of Psychiatry and Behavioral Sciences, Seattle, WA 98104, USA
    Psychosom Med 69:74-80. 2007
    ....
  49. pmc Effectiveness of therapeutic massage for generalized anxiety disorder: a randomized controlled trial
    Karen J Sherman
    Group Health Research Institute, Seattle, Washington 98101, USA
    Depress Anxiety 27:441-50. 2010
    ..This study evaluates the effectiveness of therapeutic massage for persons with generalized anxiety disorder (GAD)...
  50. ncbi request reprint Strengthening the patient-provider relationship in the aftermath of physical trauma through an understanding of the nature and severity of posttraumatic concerns
    Douglas F Zatzick
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Box 359896, HMC 325 Ninth Ave, Seattle, WA 98104, USA
    Psychiatry 70:260-73. 2007
    ....
  51. ncbi request reprint Transcranial magnetic stimulation reduces pain in patients with major depression: a sham-controlled study
    David H Avery
    Department of Psychiatry and Behavioral Sciences, Harborview Medical Center, Seattle, Washington 98104 2499, USA
    J Nerv Ment Dis 195:378-81. 2007
    ..Compared with sham, TMS was associated with a significant (p < 0.05) reduction in the SAFTEE pain item during the study. The reduction in pain could not be explained by the antidepressant effects...
  52. doi request reprint A randomized trial to increase physical activity among native elders
    Craig N Sawchuk
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98104, USA
    Prev Med 47:89-94. 2008
    ..Physical inactivity is common among older populations and American Indians. Our objective was to compare two methods for increasing physical activity and walking among American Indian elders...
  53. ncbi request reprint Education is associated with physical activity among American Indian elders
    Craig N Sawchuk
    University of Washington, Harborview Medical Center, Box 359911, 325 9th Avenue, Seattle, WA 98104, USA
    Am Indian Alsk Native Ment Health Res 15:1-17. 2008
    ..Additional research is needed to understand modifiable personal, social, and environmental physical activity barriers in these populations...
  54. ncbi request reprint The relationship between post-traumatic stress disorder, depression and cardiovascular disease in an American Indian tribe
    Craig N Sawchuk
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98104, USA
    Psychol Med 35:1785-94. 2005
    ..The purpose of this study was to compare the strength of the association of lifetime post-traumatic stress disorder (PTSD) and lifetime major depression on CVD among Northern Plains American Indians...
  55. doi request reprint Characteristics of HIV-positive patients treated in a psychiatric emergency department
    W R Murray Bennett
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Medical Center, Seattle WA 98104, USA
    Psychiatr Serv 60:398-401. 2009
    ..However, the prevalence of HIV infection among patients treated at psychiatric emergency departments is not known, and neither are the characteristics of HIV-positive patients seen in this setting...
  56. doi request reprint Impact of brief interventions and brief treatment on admissions to chemical dependency treatment
    Antoinette Krupski
    Center for Healthcare Improvement for Addictions, Mental Illness and Medically Vulnerable Populations CHAMMP, Department of Psychiatry and Behavioral Sciences, University of Washington at Harborview Medical Center, Seattle, WA 98104 2499, USA
    Drug Alcohol Depend 110:126-36. 2010
    ..The results suggest that SBIRT programs could serve an important role in increasing entry to specialized treatment for individuals with substance use disorders...
  57. pmc Racial and ethnic disparities in police-reported intimate partner violence and risk of hospitalization among women
    Sherry Lipsky
    Dept of Psychiatry and Behavioral Sciences, Center for Healthcare Improvement for Addictions, Mental Illness and Medically Vulnerable Populations, University of Washington at Harborview Medical Center, Seattle, WA 98104 2499, USA
    Womens Health Issues 19:109-18. 2009
    ..We sought to examine racial and ethnic disparities in police-reported intimate partner violence (IPV) and hospitalization rates and rate ratios among women with police-reported IPV relative to those without such reports...
  58. ncbi request reprint Predicting posttraumatic distress in hospitalized trauma survivors with acute injuries
    Douglas F Zatzick
    Department of Psychiatry, University of California Davis, USA
    Am J Psychiatry 159:941-6. 2002
    ..Few investigations have comprehensively screened for posttraumatic symptomatic distress or identified predictors of posttraumatic stress disorder (PTSD) in representative samples of surgical inpatients...
  59. ncbi request reprint The detection and treatment of posttraumatic distress and substance intoxication in the acute care inpatient setting
    Douglas Zatzick
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98104 2499, USA
    Gen Hosp Psychiatry 27:57-62. 2005
    ....
  60. ncbi request reprint Assessment and treatment of nursing home residents with depression or behavioral symptoms associated with dementia: a review of the literature
    Mark Snowden
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA
    J Am Geriatr Soc 51:1305-17. 2003
    ..There are sufficient data to formulate an evidenced-based approach to treatment of depression and behavioral symptoms, but more research is needed to prioritize treatments...
  61. doi request reprint Ethnoracial variations in acute PTSD symptoms among hospitalized survivors of traumatic injury
    Kari A Stephens
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA
    J Trauma Stress 23:384-92. 2010
    ..Disparities in trauma history, PTSD symptoms, and event related factors emphasize the need for acute care services to incorporate culturally competent approaches for treating these diverse populations...
  62. ncbi request reprint Reevaluating the association between emergency department heart rate and the development of posttraumatic stress disorder: A public health approach
    Douglas F Zatzick
    Department of Psychiatry, Harborview Medical Center, University of Washington School of Medicine, Box 359911, HMC, 325 Ninth Avenue, Seattle, WA 98104, USA
    Biol Psychiatry 57:91-5. 2005
    ..Other studies suggest no association, however...
  63. ncbi request reprint Incremental cost-effectiveness of a collaborative care intervention for panic disorder
    Wayne Katon
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, 98195 6560, USA
    Psychol Med 36:353-63. 2006
    ..This study describes the incremental cost-effectiveness of a combined cognitive behavioral therapy (CBT) and pharmacotherapy intervention for patients with panic disorder versus usual primary-care treatment...
  64. ncbi request reprint Shorter duration of depressive episode may predict response to repetitive transcranial magnetic stimulation
    Paul E Holtzheimer
    Department of Psychiatry and Behavioral Sciences, University of Washington Medical Center, Harborview Medical Center, Seattle, Washington 98104, USA
    Depress Anxiety 19:24-30. 2004
    ..Patients may need more than 10 treatments to obtain full benefit from rTMS. The design of future rTMS studies should consider these issues...
  65. ncbi request reprint A controlled study of repetitive transcranial magnetic stimulation in medication-resistant major depression
    David H Avery
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Medical Center, Seattle, 98104 2499, USA
    Biol Psychiatry 59:187-94. 2006
    ..Repetitive transcranial magnetic stimulation (TMS) as a treatment for depression has shown statistically significant effects, but the clinical significance of these effects has been questioned...
  66. ncbi request reprint Hazardous drinking by trauma patients during the year after injury
    Chris Dunn
    Department of Psychiatry, University of Washington School of Medicine, Seattle, USA
    J Trauma 54:707-12. 2003
    ..To improve reinjury prevention strategies targeting hazardous drinking, we determined its predictors and longitudinal course in the year after injury...
  67. ncbi request reprint Developing high-quality interventions for posttraumatic stress disorder in the acute care medical setting
    Douglas Zatzick
    Department of Psychiatry and Behavioral Science, University of Washington School of Medicine, Seattle, Washington, USA
    Semin Clin Neuropsychiatry 8:158-67. 2003
    ..Collaborative interventions hold promise for injured trauma survivors treated in acute care settings because they combine evidence-based PTSD interventions and patient-centered supportive care...
  68. ncbi request reprint A randomized effectiveness trial of stepped collaborative care for acutely injured trauma survivors
    Douglas Zatzick
    Department of Psychiatry and Behavioral Sciences, The Harborview Injury Prevention and Research Center, University of Washington School of Medicine, Seattle 98104, USA
    Arch Gen Psychiatry 61:498-506. 2004
    ..Although posttraumatic stress disorder (PTSD) and alcohol abuse frequently occur among acutely injured trauma survivors, few real-world interventions have targeted these disorders...
  69. ncbi request reprint Cost-effectiveness and cost offset of a collaborative care intervention for primary care patients with panic disorder
    Wayne J Katon
    Department of Psychiatry and Behavioral Sciences, Campus Box 356560, University of Washington Medical School, 1959 NE Pacific St, Seattle, WA 98195 6560, USA
    Arch Gen Psychiatry 59:1098-104. 2002
    ..This report evaluates the incremental cost-effectiveness and potential cost offset of a CC treatment program for primary care patients with panic disorder from the perspective of the payer...
  70. ncbi request reprint Does occasional cannabis use impact anxiety and depression treatment outcomes?: Results from a randomized effectiveness trial
    Jonathan B Bricker
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, Washington 98109, USA
    Depress Anxiety 24:392-8. 2007
    ..A combined CBT and medication treatment intervention may be a promising approach for the treatment of depression among occasional cannabis users...
  71. pmc Barriers and facilitators to walking and physical activity among American Indian elders
    Craig N Sawchuk
    Dean Health System, 1313 Fish Hatchery Rd, Madison, WI 53715, USA
    Prev Chronic Dis 8:A63. 2011
    ..We examined personal and built-environment barriers and facilitators to walking and physical activity and their relationship with health-related quality of life in American Indian elders...
  72. ncbi request reprint "Excessive tears": a diagnostic sign for cocaine-induced mood disorder?
    Paul Zarkowski
    Harborview Medical Center, University of Washington, Seattle, WA 98104 2499, USA
    Compr Psychiatry 48:252-6. 2007
    ..This study aims to investigate excessive tearfulness as a sign to help determine the etiology of depressive symptoms...
  73. ncbi request reprint Factors associated with high use of public mental health services by persons with borderline personality disorder
    Katherine Anne Comtois
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, 98195, USA
    Psychiatr Serv 54:1149-54. 2003
    ..The research presented here was a pilot study to identify clinical factors associated with high use (as opposed to lower use) of inpatient psychiatric services by persons with borderline personality disorder...
  74. ncbi request reprint Posttraumatic distress, alcohol disorders, and recurrent trauma across level 1 trauma centers
    Douglas Zatzick
    Department of Psychiatry and Behavioral Science, University of Washington School of Medicine, Seattle, Washington 98104 2499, USA
    J Trauma 57:360-6. 2004
    ..Injured survivors of individual and mass trauma receive their initial evaluation in acute care. Few investigations have comprehensively screened for posttraumatic stress disorder (PTSD) symptoms and related comorbidities across sites...
  75. ncbi request reprint Psychopharmacologic approaches to the management of posttraumatic stress disorders in the acute care medical sector
    Douglas Zatzick
    Department of Psychiatry and Behavioral Science, University of Washington School of Medicine, Seattle, WA, USA
    Semin Clin Neuropsychiatry 8:168-74. 2003
    ..The current pharmacotherapy recommendations also integrate considerations regarding the delivery of psychotherapeutic interventions targeting PTSD among injured trauma survivors...
  76. doi request reprint Effect of co-occurring disorders and intimate partner violence on substance abuse treatment outcomes
    Sherry Lipsky
    Center for Healthcare Improvement for Addictions, Mental Illness and Medically Vulnerable Populations CHAMMP, University of Washington at Harborview Medical Center, Seattle, WA 98104 2499, USA
    J Subst Abuse Treat 38:231-44. 2010
    ..Men with COD were less likely than those without COD to be arrested for substance-related crimes but more likely to be arrested for violence-related crimes in the follow-up period. Implications of these findings are discussed...
  77. doi request reprint Unmet need for mental health and addictions care in urban community health clinics: frontline provider accounts
    Meg Cristofalo
    Center for Healthcare Improvement for Addictions, Mental Illness and Medically Vulnerable Populations CHAMMP, Department of Psychiatry, University of Washington School of Medicine at Harborview Medical Center, Seattle, WA 98104 2499, USA
    Psychiatr Serv 60:505-11. 2009
    ....
  78. ncbi request reprint Psychological effects of hazardous materials exposures
    Dana F Kovalchick
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
    Psychosom Med 64:841-6. 2002
    ..To study psychological outcomes after hazardous materials incidents...
  79. pmc Predictors of posttraumatic stress disorder and return to usual major activity in traumatically injured intensive care unit survivors
    Dimitry S Davydow
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA 98104, USA
    Gen Hosp Psychiatry 31:428-35. 2009
    ..To assess intensive care unit (ICU)/acute care service-delivery characteristics and pre-ICU factors as predictors of posttraumatic stress disorder (PTSD) and return to usual major activity after ICU admission for trauma...
  80. ncbi request reprint Rethinking the duration requirement for generalized anxiety disorder: evidence from the National Comorbidity Survey Replication
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    Psychol Med 35:1073-82. 2005
    ....
  81. doi request reprint Impact of Access to Recovery services on alcohol/drug treatment outcomes
    Antoinette Krupski
    Center for Healthcare Improvement for Addictions, Mental Illness and Medically Vulnerable Populations CHAMMP, Department of Psychiatry and Behavioral Sciences, University of Washington at Harborview Medical Center, Seattle, WA 98104 2499, USA
    J Subst Abuse Treat 37:435-42. 2009
    ..The beneficial effects of ATR services on treatment retention were most pronounced when they were provided between 31 and 180 days after treatment began. The results reported here offer evidence for the value of ATR services...
  82. pmc Pharmacological treatment of anxiety disorders: current treatments and future directions
    Frank J Farach
    Department of Psychology, University of Washington, Seattle, WA 98195 1525, USA
    J Anxiety Disord 26:833-43. 2012
    ..We highlight directions for future research, as neither of these approaches is ready for routine clinical use...
  83. doi request reprint The use of administrative data as a substitute for individual screening scores in observational studies related to problematic alcohol or drug use
    Jeanne M Sears
    Center for Healthcare Improvement for Addictions, Mental Illness and Medically Vulnerable Populations CHAMMP, Department of Psychiatry and Behavioral Sciences, University of Washington at Harborview Medical Center, Seattle, WA 98195, USA
    Drug Alcohol Depend 111:89-96. 2010
    ..The findings further suggest that proxies for substance use disorders, such as those evaluated here, can enhance future observational studies intended to improve health care for this population...
  84. ncbi request reprint Gamma-hydroxybutyric acid (GHB) withdrawal: a case report
    W R Murray Bennett
    Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine at Harborview Medical Center, Seattle, WA 98104, USA
    J Psychoactive Drugs 39:293-6. 2007
    ....
  85. pmc Utility of the Beck Depression Inventory to screen for and track depression in injection drug users seeking hepatitis C treatment
    Paul E Holtzheimer
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322, USA
    Gen Hosp Psychiatry 32:426-32. 2010
    ..Effective screening strategies are needed to help non-psychiatric clinicians identify depressive disorders...
  86. ncbi request reprint Discussion: using benzodiazepines in clinical practice
    Samantha A Stewart
    J Clin Psychiatry 66:39-43; quiz 44-5. 2005
  87. pmc Design of the Coordinated Anxiety Learning and Management (CALM) study: innovations in collaborative care for anxiety disorders
    Greer Sullivan
    South Central VA Mental Illness Research Education and Clinical Center, Central Arkansas Veterans Healthcare System, North Little Rock, AR 72214 1706, USA
    Gen Hosp Psychiatry 29:379-87. 2007
    ..Since anxiety disorders are most often treated in primary care, quality improvement interventions, such as the Coordinated Anxiety Learning and Management (CALM) intervention, are needed in primary care...
  88. ncbi request reprint Depression: therapy or medication? Therapy and antidepressants may affect the brain differently, but both are effective
    Peter P Roy-Byrne
    Health News 10:14-5. 2004
  89. ncbi request reprint Predictors of willingness to consider medication and psychosocial treatment for panic disorder in primary care patients
    Holly Hazlett-Stevens
    University of California, Los Angeles, CA, USA
    Gen Hosp Psychiatry 24:316-21. 2002
    ....
  90. ncbi request reprint Adherence to treatment among economically disadvantaged patients with panic disorder
    Snigdha Mukherjee
    South Central Mental Illness Research, Education and Clinical Center, North Little Rock, Arkansas, USA
    Psychiatr Serv 57:1745-50. 2006
    ..The purpose of this study was to examine the feelings of disadvantaged patients about and experiences of treatment for anxiety disorders in primary care settings...
  91. ncbi request reprint Assessment of beliefs about psychotropic medication and psychotherapy: development of a measure for patients with anxiety disorders
    Alexander Bystritsky
    Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA
    Gen Hosp Psychiatry 27:313-8. 2005
    ..This study presents the psychometric properties of a brief measure to assess beliefs about psychotropic medications and psychotherapy among patients with anxiety disorders...
  92. ncbi request reprint Correlates of alcohol use among anxious and depressed primary care patients
    Joanna J Arch
    Department of Psychology, University of California, Los Angeles, 90095 1563, USA
    Gen Hosp Psychiatry 28:37-42. 2006
    ..The purpose of this study is to determine the patterns of alcohol use for primary care patients with anxiety disorders and/or major depression in three urban university-affiliated outpatient clinics...
  93. ncbi request reprint Relationships among pain, anxiety, and depression in primary care
    Adrienne J Means-Christensen
    Department of Psychology, Radford University, Radford, Virginia, USA
    Depress Anxiety 25:593-600. 2008
    ..An awareness of these relationships may be particularly important in primary care settings where a patient who presents with reports of pain may have an undiagnosed anxiety or depressive disorder...
  94. ncbi request reprint Social anxiety in primary care: hidden in plain view?
    Peter P Roy-Byrne
    Gen Hosp Psychiatry 27:155-7. 2005

Research Grants10

  1. Brief Intervention in Primary Care for Problem Drug Use and Abuse
    Peter Roy Byrne; Fiscal Year: 2009
    ..The results of the study will have implications for whether it is advisable to expand its application beyond hazardous alcohol abuse to include abuse of drugs. ..
  2. CALM: Improving Primary Care Outcomes
    Peter Roy Byrne; Fiscal Year: 2007
    ..g. instrumental variables) to examine the effects of appropriate treatment, independent of intervention assignment, on functioning and other clinical outcomes; and (2) to estimate health care costs and cost effectiveness of CALM. ..
  3. Treating Anxiety in Public Sector Medical Settings
    Peter Roy Byrne; Fiscal Year: 2007
    ..As my skills in this latter area evolve over the course of this award, I hope to be able to mentor them even more effectively in this specific area as well. ..
  4. IMPROVING CARE FOR PANIC DISORDER IN PRIMARY CARE
    Peter Roy Byrne; Fiscal Year: 2002
    ..abstract_text> ..
  5. Brief Intervention in Primary Care for Problem Drug Use and Abuse
    Peter P Roy Byrne; Fiscal Year: 2010
    ..The results of the study will have implications for whether it is advisable to expand its application beyond hazardous alcohol abuse to include abuse of drugs. ..