Research Topics
| P T RowleySummaryAffiliation: University of Rochester Country: USA Publications
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Detail Information
Publications
Impact of genetic counseling and DNA testing on individuals with colorectal cancer with a positive family history: a population-based studyStarlene Loader
Department of Medicine, Division of Genetics, University of Rochester School of Medicine, NY 14642, USA
Genet Test 9:313-9. 2005..05). This study suggests that individuals undergoing a genetic evaluation for an inherited susceptibility to colorectal cancer pursue recommended surveillance and inform relatives of their result...
Prenatal screening for cystic fibrosis carriers: an economic evaluationP T Rowley
Department of Medicine, Division of Genetics, Unviersity of Rochester School of Medicine, NY, USA
Am J Hum Genet 63:1160-74. 1998..This value compares favorably with that of many accepted medical services. The cost of prenatal CF carrier screening could fall to equal the averted costs of CF patient care if the cost of carrier testing were to fall to $100...
Circular antisense oligonucleotides inhibit growth of chronic myeloid leukemia cellsP T Rowley
Department of Medicine and Division of Genetics, University of Rochester, NY 14642, USA
Mol Med 5:693-700. 1999..First, circular agents, having no ends, are exonuclease-resistant. Second, they bind to complementary strands of RNA and DNA with a higher affinity than corresponding linear agents...
Telomerase inhibitorsP T Rowley
Department of Medicine and Division of Genetics, University of Rochester School of Medicine, Rochester, New York 14642, USA
Anticancer Res 20:4419-29. 2000..A specific inhibitor is expected to immediately inhibit activity but not cell division, produce telomerase shortening over multiple generations, and ultimately produce end-to-end chromosomal fusion and growth arrest...
Points to consider in designing a clinical trial to ascertain the utility of a genetic screening testP T Rowley
Division of Genetics, University of Rochester School of Medicine, 601 Elmwood Avenue, Box 641, Rochester, NY 14642 0001, USA
Genet Test 5:219-21. 2001....
Screening for an inherited susceptibility to colorectal cancerPeter T Rowley
Department of Medicine and Division of Genetics, University of Rochester, Rochester, NY 14642, USA
Genet Test 8:421-30. 2004..Individuals who decline are often concerned about their own or their family's emotional reaction or fear discrimination...
Inherited susceptibility to colorectal cancerPeter T Rowley
Department of Medicine and Division of Genetics, University of Rochester, Rochester, New York 14642, USA
Annu Rev Med 56:539-54. 2005....
Commentary: considering family covenantsPeter T Rowley
Division of Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA
Genet Test 7:323. 2003
Patient vs. physician as the target of educational outreach about screening for an inherited susceptibility to colorectal cancerStarlene Loader
Department of Medicine, University of Rochester School of Medicine, Rochester, NY 14642, USA
Genet Test 6:281-90. 2002..education via their physician, did not significantly differ in terms of percentages of patients receiving counseling (42% vs. 51%, respectively) or the percentage choosing DNA testing (32% vs. 37%, respectively)...
Family issues in a psychoeducation group for women with a BRCA mutationJ Speice
Departments of Psychiatry and Medicine, Wynne Center for Family Research, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Clin Genet 62:121-7. 2002..In addition, referrals for a psychoeducation group, community support group, or psychotherapy may be useful for individuals, couples and families who are considering genetic testing for BRCA mutations...
Induction of megakaryocytic characteristics in human leukemic cell line K562: polyploidy, inducers, and secretion of mitogenic activityJ F Leary
Department of Medicine, University of Rochester School of Medicine, New York
J Biol Regul Homeost Agents 1:73-80. 1987..Second, phorbol dibutyrate induces polyploidy, a feature of normal megakaryocyte development. Third, mezerein and teleocidin, nonphorbol ester tumor promotors, also induce development of multinuclearity and polyploidy...
Impact of genetic testing for breast-ovarian cancer susceptibilityStarlene Loader
Department of Medicine, Division of Genetics, University of Rochester School of Medicine, Rochester, NY 14642, USA
Genet Test 8:1-12. 2004..The index patients, i.e., the ones who want the risk information most, appear to undergo the most stress in obtaining it...
Cystic fibrosis newborn screening: a pilot study to maximize carrier screeningErin Lagoe
Department of Pediatrics, Division of Genetics, University of Rochester School of Medicine, Rochester, New York 14642, USA
Genet Test 9:255-60. 2005..Such identification detects trait-trait parents and facilitates carrier testing among relatives...
