Research Topics
Species | Howard A RowleySummaryAffiliation: University of Wisconsin Country: USA Publications
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Publications
Clinical perspectives in perfusion: neuroradiologic applicationsHoward A Rowley
Department of Radiology, University of Wisconsin, Madison, 53792, USA
Top Magn Reson Imaging 15:28-40. 2004..Several key clinical indications are introduced, such as acute cerebral ischemia, chronic vascular disease, and tumors...
fMRI activation during episodic encoding and metacognitive appraisal across the lifespan: risk factors for Alzheimer's diseaseMehul A Trivedi
Geriatric Research Education and Clinical Center, Wm S Middleton Memorial Veterans Hospital, Madison, WI 53705, USA
Neuropsychologia 46:1667-78. 2008..These results suggest that FH and aging are exerting independent effects in both tasks while APOE affected the relationship with age in the hippocampus in one of the two tasks given...- Medial prefrontal functional connectivity--relation to memory self-appraisal accuracy in older adults with and without memory disordersMichele L Ries
Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, WI 53705, USA
Neuropsychologia 50:603-11. 2012..Results reported here corroborate findings of variable memory self-appraisal accuracy during the earliest emergence of AD symptoms and reveal alterations in MPFC functional connectivity that correspond to impaired memory self-appraisal... - The influence of parental history of Alzheimer's disease and apolipoprotein E epsilon4 on the BOLD signal during recognition memoryGuofan Xu
Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, WI 53705, USA
Brain 132:383-91. 2009..The findings lend further support to the idea that functional brain changes may begin far in advance of symptomatic Alzheimer's disease... - White matter in aging and cognition: a cross-sectional study of microstructure in adults aged eighteen to eighty-threeBarbara B Bendlin
Geriatric Research Educational and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, USA
Dev Neuropsychol 35:257-77. 2010..The complex relationships between cognition, white matter microstructure, and white matter volume still require further investigation... - Magnetic resonance imaging characterization of brain structure and function in mild cognitive impairment: a reviewMichele L Ries
William S Middleton Memorial Veterans Hospital Geriatric Research Education and Clinical Center, Madison, Wisconsin 53705, USA
J Am Geriatr Soc 56:920-34. 2008..Third, we will make recommendations regarding the current clinical use of MRI in identification of MCI. As a conclusion, we will look to the future of neuroimaging as a tool in early AD detection... - Effect of Alzheimer disease risk on brain function during self-appraisal in healthy middle-aged adultsSterling C Johnson
Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, 2500 Overlook Terrace, Madison, WI 53705, USA
Arch Gen Psychiatry 64:1163-71. 2007.... - Anosognosia in mild cognitive impairment: Relationship to activation of cortical midline structures involved in self-appraisalMichele L Ries
Geriatric Research Education and Clinical Center, William S Middleton VA Hospital, Madison, Wisconsin 53705, USA
J Int Neuropsychol Soc 13:450-61. 2007..This finding highlights the level of anosognosia in MCI as an important predictor of response to self-appraisal in cortical midline structures, brain regions vulnerable to changes in early AD... - Effects of hypoperfusion in Alzheimer's diseaseBenjamin P Austin
UW Cardiovascular Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 3252, USA
J Alzheimers Dis 26:123-33. 2011..Finally, given that perfusion is a vascular phenomenon, we provide insights from a vascular lesion model (i.e., stroke) and illustrate the influence of disrupted perfusion on brain structure and function and, ultimately, cognition in AD... - Longitudinal changes in patients with traumatic brain injury assessed with diffusion-tensor and volumetric imagingBarbara B Bendlin
Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, WI, USA
Neuroimage 42:503-14. 2008.... - Reliability and precision of pseudo-continuous arterial spin labeling perfusion MRI on 3.0 T and comparison with 15O-water PET in elderly subjects at risk for Alzheimer's diseaseGuofan Xu
GRECC, Madison VA Hospital, Madison, WI, USA
NMR Biomed 23:286-93. 2010..pcASL perfusion MRI offers an alternative method for non-invasive in vivo examination of early pathophysiological changes in AD... - Hemiplegic migraine: hyperperfusion and abortive therapy with intravenous verapamilDavid A Hsu
Department of Neurology H6 526, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, USA
Brain Dev 30:86-90. 2008..The beneficial effect of verapamil on headache but not hemiplegia suggests a distinct mechanism for pain and neuronal dysfunction in hemiplegic migraine, with the beneficial effect on pain not due to vasodilation... - Longitudinal changes in global brain volume between 79 and 409 days after traumatic brain injury: relationship with duration of comaMehul A Trivedi
William S Middleton Memorial VA Hospital, Geriatric Research Education and Clinical Center GRECC, Madison, Wisconsin 53705, USA
J Neurotrauma 24:766-71. 2007..Greater %BVC was associated with longer duration of post-injury coma. These results confirm previous findings from cross-sectional studies and argue that the brain undergoes continued structural change for several months post-injury... - The cerebral response during subjective choice with and without self-referenceSterling C Johnson
William S Middleton VA Medical Center, Madison, WI 53705, USA
J Cogn Neurosci 17:1897-906. 2005..The findings suggest that self-referential processing, rather than subjective judgments among ambiguous response alternatives, accounted for the AMPFC and RSC response... - Effects of atorvastatin on cerebral blood flow in middle-aged adults at risk for Alzheimer's disease: a pilot studyCynthia M Carlsson
Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA
Curr Alzheimer Res 9:990-7. 2012..Statins improve vascular reactivity, but it is unknown if they increase regional cerebral blood flow (CBF) in individuals at risk for AD... - Longitudinal volumetric changes following traumatic brain injury: a tensor-based morphometry studyKimberly D M Farbota
Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, Wisconsin 53792, USA
J Int Neuropsychol Soc 18:1006-18. 2012.... - Evaluation of a signal intensity mask in the interpretation of functional MR imaging activation mapsRoberta M Strigel
Department of Radiology, University of Wisconsin, Madison, 53792-3252, USA
AJNR Am J Neuroradiol 26:578-84. 2005..The availability of the SIM may affect interpretation of the fMRI... - The use of quick-brain magnetic resonance imaging in the evaluation of shunt-treated hydrocephalusBermans J Iskandar
Department of Neurological Surgery, University of Wisconsin, Madison, Wisconsin 53792, USA
J Neurosurg 101:147-51. 2004.... - Variability of clinical CT perfusion measurements in patients with carotid stenosisAquilla S Turk
Department of Radiology, University of Wisconsin Hospital and Clinics, Madison, WI, USA
Neuroradiology 49:955-61. 2007..The magnitude of variability in clinical measurements has been insufficiently evaluated. The purpose of this study was to measure the long-term variability of clinical pCT measurements in patients with cerebrovascular disease... - Multicenter, double-blind, randomized, intra-individual crossover comparison of gadobenate dimeglumine and gadopentetate dimeglumine in MRI of brain tumors at 3 teslaZoran Rumboldt
Medical University of South Carolina, Department of Radiology, Charleston, SC, USA
J Magn Reson Imaging 29:760-7. 2009..To prospectively compare 0.1 mmol/kg doses of gadobenate dimeglumine and gadopentetate dimeglumine for contrast-enhanced MRI of brain lesions at 3 Tesla (T)... - Cortical blindness: clinical and radiologic findings in reversible posterior leukoencephalopathy syndrome: case report and review of the literatureAlon Kahana
Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine, Madison, Wisconsin 53705, USA
Ophthalmology 112:e7-e11. 2005..Prompt diagnosis will also help to avoid potentially dangerous invasive procedures such as thrombolytic therapy... - Confounding effect of large vessels on MR perfusion images analyzed with independent component analysisTimothy J Carroll
Department of Medical Physics, University of Wisconsin, Madison, WI, USA
AJNR Am J Neuroradiol 23:1007-12. 2002..CONCLUSION: The removal of the signal resulting from large blood vessels before calculation of rCBF resulted in images with significantly less artifact and higher image quality... - Automatic calculation of the arterial input function for cerebral perfusion imaging with MR imagingTimothy J Carroll
Department of Medical Physics, University of Wisconsin, Madison, USA
Radiology 227:593-600. 2003..It is possible to reliably determine the AIF at dynamic susceptibility contrast MR imaging and eliminate the need for operator input and lengthy postprocessing... - Effects of refocusing flip angle modulation and view ordering in 3D fast spin echoReed F Busse
GE Healthcare, MR Applied Science Lab, Madison, Wisconsin 53717, USA
Magn Reson Med 60:640-9. 2008.... - Utility of computed tomography perfusion in detection of cerebral vasospasm in patients with subarachnoid hemorrhageRoham Moftakhar
Department of Neurosurgery, University of Wisconsin Hospital and Clinics, Madison, Wisconsin, USA
Neurosurg Focus 21:E6. 2006..It can be used as a tool to help guide the decision to pursue DS angiography with the intent to treat vasospasm... - Neural correlates of self-evaluative accuracy after traumatic brain injuryTaylor W Schmitz
William S. Middleton VA Medical Center, 2500 Overlook Terrace (11G, Madison, WI 53705, USA
Neuropsychologia 44:762-73. 2006..The results suggest that one's post-injury level of self-referential insight is related to a network inclusive of the medial and right dorsal PFC... - Extending the time window for thrombolysis: evidence from acute stroke trialsHoward A Rowley
Department of Radiology, University of Wisconsin, Madison, WI 53792, USA
Neuroimaging Clin N Am 15:575-87, x. 2005..Advanced imaging with CT or MR imaging protocols is providing a means for rational physiologic selection and outcomes assessment in stroke treatment... - Computed tomographic findings in patients undergoing intra-arterial thrombolysis for acute ischemic stroke due to middle cerebral artery occlusion: results from the PROACT II trialHeidi C Roberts
Department of Radiology, University of California, San Francisco, USA
Stroke 33:1557-65. 2002..The purpose of this study was to evaluate the role of noncontrast CT in the selection of patients to receive thrombolytic therapy for acute ischemic stroke and to predict radiological and clinical outcomes... 
Improved motion correction capabilities for fast spin echo T1 FLAIR propeller using non-cartesian external calibration data driven parallel imagingJames H Holmes
Global Applied Science Laboratory, GE Healthcare, Madison, Wisconsin 53705 2275, USA
Magn Reson Med 68:1856-65. 2012....- Consistency of interictal and ictal onset localization using magnetoencephalography in patients with partial epilepsyLilly Tang
Department of Radiology, University of California at San Francisco, California, USA
J Neurosurg 98:837-45. 2003..These findings support the interpretation of interictal spikes on MEG as a useful and effective noninvasive method for localizing primary seizure foci... - High-resolution 3D T2-weighted fast spin echo: new applications in the orbitErin M Simon
Department of Radiology, University of California San Francisco, San Francisco, CA, USA
Neuroradiology 45:489-92. 2003..Such an approach improves diagnostic confidence and may eliminate the need for a dedicated surface coil examination... - Selection of acute ischemic stroke patients for intra-arterial thrombolysis with pro-urokinase by using ASPECTSMichael D Hill
Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Foothills Hospital, Calgary, Alberta, Canada
Stroke 34:1925-31. 2003.... - Diffusion weighted magnetic resonance imaging in strokeTimothy P L Roberts
Department of Medical Imaging, University of Toronto, 150 College St Rm 88, Toronto, ON, Canada M5S 3E2
Eur J Radiol 45:185-94. 2003.... - Magnetic source imaging demonstrates altered cortical distribution of function in patients with arteriovenous malformationsG Edward Vates
Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143, USA
Neurosurgery 51:614-23; discussion 623-7. 2002..We used magnetic source imaging (MSI) to identify the central sulcus and to determine whether primary cortical function was shifted in a set of 30 patients. We correlated these findings with outcome after treatment... - Factors influencing outcome and treatment effect in PROACT IILawrence R Wechsler
University of Pittsburgh, Pittsburgh, PA, USA
Stroke 34:1224-9. 2003..The purpose of the current study was to examine baseline factors to determine predictors of good outcome and response to treatment... - Preoperative magnetic source imaging for brain tumor surgery: a quantitative comparison with intraoperative sensory and motor mappingHagen Schiffbauer
Department of Neurosurgery, University of Tubingen, Germany
Neurosurg Focus 15:E7. 2003..Thus, MS imaging can be considered a valuable and accurate planning adjunct in the treatment of patients with intraaxial brain tumors... - Preoperative magnetic source imaging for brain tumor surgery: a quantitative comparison with intraoperative sensory and motor mappingHagen Schiffbauer
Department of Neurosurgery, , Germany
J Neurosurg 97:1333-42. 2002..Thus, MS imaging can be considered a valuable and accurate planning adjunct in the treatment of patients with intraaxial brain tumors... - Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasmBrian P Witwer
Department ofNeurological Surgery, University of Wisconsin School of Medicine, Madison 53792, USA
J Neurosurg 97:568-75. 2002..Whether resection of these involved fibers results in subtle postoperative neurological deficits requires further systematic study... - White matter tractography using diffusion tensor deflectionMariana Lazar
Department of Physics, University of Utah, Salt Lake City, Utah, USA
Hum Brain Mapp 18:306-21. 2003..This approach is promising for mapping the organizational patterns of white matter in the human brain as well as mapping the relationship between major fiber trajectories and the location and extent of brain lesions... - Three-dimensional high-resolution magnetic resonance imaging of ocular and orbital malignanciesSharon McCaffery
Department of Ophthalmology, University of California-San Francisco, 94143-0730, USA
Arch Ophthalmol 120:747-54. 2002..It is particularly useful in the evaluation of intraocular tumors and the nerve-sheath complex. This new technique contributes significantly to improved diagnosis and management in patients with ocular and orbital malignancies... - Dose Escalation of Desmoteplase for Acute Ischemic Stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onsetAnthony J Furlan
Department of Neurology, The Cleveland Clinic, Cleveland, OH 44195, USA
Stroke 37:1227-31. 2006..This study evaluated safety and efficacy of intravenous (IV) desmoteplase in patients with perfusion/diffusion mismatch on MRI 3 to 9 hours after onset of acute ischemic stroke...