NEIL EDWARD ROWLAND

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Food or fluid restriction in common laboratory animals: balancing welfare considerations with scientific inquiry
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL, USA
    Comp Med 57:149-60. 2007
  2. doi request reprint Restricted temporal access to food and anorexia in mice: Microstructure of eating within feeding opportunities
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL 32611, USA Electronic address
    Appetite 96:621-7. 2016
  3. doi request reprint Economics of food intake in mice: energy yield of the reinforcer
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville FL 32611 2250, USA Electronic address
    Physiol Behav 136:104-10. 2014
  4. doi request reprint Action of a serotonergic anorectic in meal-fed mice working for food
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, Florida 32611 2250, USA
    Behav Pharmacol 23:560-6. 2012
  5. pmc Order and disorder: temporal organization of eating
    Neil E Rowland
    Department of Psychology, University of Florida, PO Box 112250, Gainesville, FL 32611 2250, USA
    Behav Brain Res 231:272-8. 2012
  6. ncbi request reprint Matching salt intake to physiological need in rats using foraging protocols
    N E Rowland
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, USA
    Braz J Med Biol Res 40:713-20. 2007
  7. doi request reprint Animal models of overeating
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL, USA
    Methods Mol Biol 829:367-75. 2012
  8. pmc Effect of MTII on food intake and brain c-Fos in melanocortin-3, melanocortin-4, and double MC3 and MC4 receptor knockout mice
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, United States
    Peptides 31:2314-7. 2010
  9. pmc Effect of serotonergic anorectics on food intake and induction of Fos in brain of mice with disruption of melanocortin 3 and/or 4 receptors
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL, USA
    Pharmacol Biochem Behav 97:107-11. 2010
  10. pmc Effect of (-)-trans-PAT, a novel 5-HT2C receptor agonist, on intake of palatable food in mice
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, USA
    Pharmacol Biochem Behav 91:176-80. 2008

Research Grants

Collaborators

Detail Information

Publications42

  1. ncbi request reprint Food or fluid restriction in common laboratory animals: balancing welfare considerations with scientific inquiry
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL, USA
    Comp Med 57:149-60. 2007
    ..In the case of chronic food restriction, the use of species-, age-, and strain-specific target growth rates is more appropriate than using a fraction of age-matched free-fed animal weights as a target...
  2. doi request reprint Restricted temporal access to food and anorexia in mice: Microstructure of eating within feeding opportunities
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL 32611, USA Electronic address
    Appetite 96:621-7. 2016
    ..We discuss the role of effort or time in FUP-induced anorexia, and suggest this murine model may emulate some aspects of human anorexia nervosa better than current activity-based protocols. ..
  3. doi request reprint Economics of food intake in mice: energy yield of the reinforcer
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville FL 32611 2250, USA Electronic address
    Physiol Behav 136:104-10. 2014
    ..New analyses of distributions of responding are presented which suggest that mice work for "target" numbers of food rewards with only a small influence of price or energy gain. ..
  4. doi request reprint Action of a serotonergic anorectic in meal-fed mice working for food
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, Florida 32611 2250, USA
    Behav Pharmacol 23:560-6. 2012
    ..Within a meal, the effect of the drug was the greatest in the first half of the available time. Therefore, the anorectic effect of DNOR was modified by the concurrent cost of food...
  5. pmc Order and disorder: temporal organization of eating
    Neil E Rowland
    Department of Psychology, University of Florida, PO Box 112250, Gainesville, FL 32611 2250, USA
    Behav Brain Res 231:272-8. 2012
    ..It is further argued that the modern human food environment is so immoderate that physiological manipulations designed to restrain eating have little hope of achieving this goal...
  6. ncbi request reprint Matching salt intake to physiological need in rats using foraging protocols
    N E Rowland
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, USA
    Braz J Med Biol Res 40:713-20. 2007
    ..There are reasons to believe that such a bias toward overconsumption may have been beneficial over evolutionary time, but such biasing for salt and other commodities is maladaptive in a resource-rich environment...
  7. doi request reprint Animal models of overeating
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL, USA
    Methods Mol Biol 829:367-75. 2012
    ..I restrict the discussion to rats and mice, used in the overwhelming majority of preclinical studies, and more specifically to protocols of diet-induced obesity and those that emulate binge eating...
  8. pmc Effect of MTII on food intake and brain c-Fos in melanocortin-3, melanocortin-4, and double MC3 and MC4 receptor knockout mice
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, United States
    Peptides 31:2314-7. 2010
    ..These data suggest that both receptor subtypes are involved in the behavioral action of MTII, and that the critical receptors are in different brain regions...
  9. pmc Effect of serotonergic anorectics on food intake and induction of Fos in brain of mice with disruption of melanocortin 3 and/or 4 receptors
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL, USA
    Pharmacol Biochem Behav 97:107-11. 2010
    ..These data suggest that MC3Rs may be involved in the response to serotonergic anorectic agents, and more generally in control of food intake...
  10. pmc Effect of (-)-trans-PAT, a novel 5-HT2C receptor agonist, on intake of palatable food in mice
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, USA
    Pharmacol Biochem Behav 91:176-80. 2008
    ....
  11. doi request reprint Nicotine analog inhibition of nicotine self-administration in rats
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, USA
    Psychopharmacology (Berl) 199:605-13. 2008
    ..Partial agonists and antagonists of addictive drugs have been useful in the treatment of dependence...
  12. pmc Feeding behavior, obesity, and neuroeconomics
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, United States
    Physiol Behav 93:97-109. 2008
    ..The fact is that humans are eating more and gaining weight in favorable food environments in exactly the way predicted from some of these models, and this has implications for the appropriate way to treat obesity...
  13. ncbi request reprint Anorectic effect of dehydroepiandrosterone combined with dexfenfluramine or thionisoxetine
    N E Rowland
    Department of Psychology, University of Florida, P O Box 112250, Center Drive, Gainesville, FL 32611 2250, USA
    Eur J Pharmacol 419:61-4. 2001
    ..Isobolographic analysis showed that the effect of dehydroepiandrosterone combined with either dexfenfluramine or thionisoxetine was within the range predicted for additivity of action...
  14. ncbi request reprint Accurate caloric compensation in rats for electively consumed ethanol-beer or ethanol-polycose mixtures
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, USA
    Pharmacol Biochem Behav 80:109-14. 2005
    ..Thus, unlike some reports in humans, rats seem able to compensate accurately for alcohol calories and in particular when, as with most alcohol consumption by humans, these are presented in palatable vehicles...
  15. ncbi request reprint Brain muscarinic receptor subtypes mediating water intake and Fos following cerebroventricular administration of bethanecol in rats
    Neil E Rowland
    Department of Psychology, University of Florida, P O Box 112250, Gainesville, FL 32611 2250, USA
    Psychopharmacology (Berl) 167:174-9. 2003
    ..The brain regions and receptor subtypes involved in water intake following central cholinergic stimulation have been incompletely characterized...
  16. ncbi request reprint The vagus nerve and thirst
    Neil E Rowland
    Department of Psychology, University of Florida, P O Box 112250, UF, Gainesville, FL 32611 2250, USA
    Physiol Behav 82:75-80. 2004
    ..Many of the questions that were raised by Smith during these pioneering studies remain unaddressed and unanswered...
  17. ncbi request reprint Acute anorectic effect of single and combined drugs in mice using a non-deprivation protocol
    N E Rowland
    Department of Psychology, University of Florida, Gainesville 32611 2250, USA
    Psychopharmacology (Berl) 157:193-6. 2001
    ..Studies of the effect of anorectic drugs such as fenfluramine in mice have indicated the desirability of using experimental protocols that do not involve deprivation...
  18. ncbi request reprint Sodium appetite induced in rats by chronic administration of a thiazide diuretic
    Neil E Rowland
    Department of Psychology, University of Florida, P O Box 112250, Gainesville, FL 32611 2250, USA
    Physiol Behav 79:613-9. 2003
    ..Administration of HCZ in food is a simple and reliable method for inducing a sustained, substantial, and need-based salt appetite in rats...
  19. ncbi request reprint Effects of the cannabinoid receptor antagonist SR 141716, alone and in combination with dexfenfluramine or naloxone, on food intake in rats
    N E Rowland
    Department of Psychology, PO Box 112250, University of Florida, Gainesville FL 32611 2250, USA
    Psychopharmacology (Berl) 159:111-6. 2001
    ....
  20. ncbi request reprint Flavor avoidance induced by LiCl and dexfenfluramine in rats and mice using nondeprivation protocols
    Neil E Rowland
    Department of Psychology, University of Florida, Gainesville 32611 2250, USA
    Behav Neurosci 116:777-84. 2002
    ..Compared with rats, mice required higher doses of these agents, avoidance was not complete after many pairings, and there was no generalization to the CS-...
  21. ncbi request reprint Relationship between anorexia and loss of serotonin uptake sites in brain of mice and rats receiving d-norfenfluramine or d-fenfluramine
    Neil E Rowland
    Department of Psychology, University of Florida, POB 112250, Gainesville, FL 32611 2250, USA
    Pharmacol Biochem Behav 77:541-6. 2004
    ..The data are discussed in terms of the species difference in behavioral tolerance and differences in neurochemical profile of D-F and D-NF...
  22. ncbi request reprint Sodium deficiency and salt appetite in ICR: CD1 mice
    Neil E Rowland
    Department of Psychology, University of Florida, PO Box 112250, Gainesville, FL 32611 2250, USA
    Physiol Behav 80:629-35. 2004
    ..5-1.5 M, and that appetite was selective for sodium but not the anion with which it was paired...
  23. ncbi request reprint LiCl-induced flavor avoidance compared between rats and mice using a nondeprivation protocol
    Neil E Rowland
    Psychology Dept, PO Box 112250, Center Dr, Univ of Florida, Gainesville FL 32611 2250, USA
    Am J Physiol Regul Integr Comp Physiol 286:R260-8. 2004
    ....
  24. ncbi request reprint Effect of repeated administration of dexfenfluramine on feeding and brain Fos in mice
    Neil E Rowland
    Department of Psychology, University of Florida, PO Box 112250, Gainesville, FL 32611 2250, USA
    Physiol Behav 78:295-301. 2003
    ..Thus, while DFEN pretreatments reduce the effects of DFEN in many brain regions in both rats and mice, mice are unlike rats insofar as there is no tolerance to the anorectic action, at least in the nondeprivation protocol used here...
  25. ncbi request reprint Role of angiotensin in body fluid homeostasis of mice: fluid intake, plasma hormones, and brain Fos
    Neil E Rowland
    University of Florida, Department of Psychology, Gainesville, Florida 32611 2250, USA
    Am J Physiol Regul Integr Comp Physiol 284:R1586-94. 2003
    ..ANG II appears to have a modified role in the behavioral response to fluid loss in mice compared with rats...
  26. doi request reprint Selection of a palatable dietary option is not preferentially reduced by cannabinoid CB1 receptor antagonist AM251 in female C57Bl/6J mice
    Clare M Mathes
    Department of Psychology, University of Florida, PO Box 112250, Gainesville, FL 32611 2250, USA
    Pharmacol Biochem Behav 94:119-23. 2009
    ..This difference from results in rats suggests that the effect of AM251 on palatable food intake may only be evident in models that induce overconsumption and/or that rats and mice may react differently to CB1 receptor antagonists...
  27. ncbi request reprint Role of angiotensin in body fluid homeostasis of mice: effect of losartan on water and NaCl intakes
    Emily C Crews
    Department of Psychology, University of Florida, P O Box 112250, Gainesville, FL 32611 2250, USA
    Am J Physiol Regul Integr Comp Physiol 288:R638-44. 2005
    ....
  28. ncbi request reprint Characteristics of salt appetite in chronically sodium-depleted rats using a progressive ratio schedule of procurement
    Laura J Starr
    Department of Psychology, University of Florida, Gainesville FL 32611 2250, USA
    Physiol Behav 88:433-42. 2006
    ....
  29. pmc Comparison of C57BL/6 and DBA/2 mice in food motivation and satiety
    Deniz Atalayer
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, USA
    Physiol Behav 99:679-83. 2010
    ....
  30. pmc Intermittent high-dose ethanol exposures increase motivation for operant ethanol self-administration: possible neurochemical mechanism
    Zhimin Li
    Department of Pharmacodynamics, Box 100487, University of Florida, Gainesville, FL 32610, USA
    Brain Res 1310:142-53. 2010
    ....
  31. ncbi request reprint Sodium preference and appetite in rats in an operant protocol
    Connie L Colbert
    Psychology Department, University of Florida, P O Box 112250, UF, Gainesville, FL 32611 2250, USA
    Physiol Behav 83:715-21. 2005
    ..This report is the first laboratory simulation of environmental factors that affect the episodic or temporal organization of sodium appetite...
  32. pmc Effect of high-fat diet during gestation, lactation, or postweaning on physiological and behavioral indexes in borderline hypertensive rats
    Anaya Mitra
    Psychology, Univ of Florida, Gainesville, FL 32611 2250, USA
    Am J Physiol Regul Integr Comp Physiol 296:R20-8. 2009
    ..The postweaning effects of junk food diet were evident on the majority of the parameters measured, including body weight, fat pad mass, serum leptin and insulin levels, and operant performance...
  33. pmc Food demand functions in mice
    Melissa A Chaney
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, USA
    Appetite 51:669-75. 2008
    ..These data show in mice that large changes in unit price or consummatory cost have relatively small effects on demand and meal patterns, but small amounts of foraging (procurement) cost have very large effects...
  34. pmc Cannabinoid-1 receptor antagonists reduce caloric intake by decreasing palatable diet selection in a novel dessert protocol in female rats
    Clare M Mathes
    Department of Psychology, University of Florida, Gainesville, Florida 32611 2250, USA
    Am J Physiol Regul Integr Comp Physiol 295:R67-75. 2008
    ..This supports the hypothesis that these CB1 receptor antagonists impact feeding by modulating the perception of palatability...
  35. pmc PKU is a reversible neurodegenerative process within the nigrostriatum that begins as early as 4 weeks of age in Pah(enu2) mice
    Jennifer E Embury
    Department of Biochemistry and Molecular Biology, PO Box 100245, College of Medicine, University of Florida, Gainesville, FL 32610, USA
    Brain Res 1127:136-50. 2007
    ....
  36. pmc Meal patterns of mice under systematically varying approach and unit costs for food in a closed economy
    Deniz Atalayer
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, USA
    Physiol Behav 98:85-93. 2009
    ..Thus, meal patterns in mice are sensitive to approach cost while total amount consumed is more sensitive to unit price. These data are discussed in terms of the concept of foraging cost as either a unitary or a multidimensional variable...
  37. ncbi request reprint Meal patterns of lean and leptin-deficient obese mice in a simulated foraging environment
    Cheryl H Vaughan
    Department of Psychology, University of Florida, Psychology Building, PO Box 112250, Gainesville, FL 32611 2250, USA
    Physiol Behav 79:275-9. 2003
    ....
  38. pmc High temporal resolution of amino acid levels in rat nucleus accumbens during operant ethanol self-administration: involvement of elevated glycine in anticipation
    Zhimin Li
    Department of Pharmacodynamics, University of Florida, Gainesville, Florida 32610, USA
    J Neurochem 106:170-81. 2008
    ..Thus, increases in glycine in nucleus accumbens appear to be related to anticipation of reinforcement...
  39. ncbi request reprint Effect of opioid and cannabinoid receptor antagonism on orphanin FQ-induced hyperphagia in rats
    Thomas A Pietras
    Department of Psychology, University of Florida, P O Box 112250, Gainesville, FL 32611 2250, USA
    Eur J Pharmacol 442:237-9. 2002
    ..The combination of these two agents inhibited food intake in a manner suggestive of additivity or supra-additivity...
  40. ncbi request reprint Effects of central and peripheral injections of apelin on fluid intake and cardiovascular parameters in rats
    Anaya Mitra
    Department of Psychology, University of Florida, Gainesville, FL 32611 2250, USA
    Physiol Behav 89:221-5. 2006
    ....
  41. ncbi request reprint Effect of two types of environmental enrichment for singly housed mice on food intake and weight gain
    Kimberly L Robertson
    Department of Psychology, University of Florida, 114 Psychology Bldg, PO Box 112250, Gainesville, FL 32611, USA
    Lab Anim (NY) 34:29-32. 2005
    ..The authors tested the effects of two environmental enrichment options on food intake and weight gain in singly housed mice. Their results may be helpful in developing rodent enrichment programs...
  42. pmc Food demand and meal size in mice with single or combined disruption of melanocortin type 3 and 4 receptors
    Deniz Atalayer
    Department of Psychology, University of Florida, Gainesville, Florida 32611 2250, USA
    Am J Physiol Regul Integr Comp Physiol 298:R1667-74. 2010
    ..These data are discussed in terms of demand functions for food intake, MC receptors involved in feeding, and their relation to actions of gut hormones, such as CCK, and to obesity...

Research Grants2

  1. Cue dependency with intravenous nutrients and nicotine
    Neil Rowland; Fiscal Year: 2007
    ..These studies may help to develop ways in conditioned preferences can be manipulated to prevent or treat certain addictive disorders, including overeating. [unreadable] [unreadable] [unreadable]..
  2. Physiology and genetics of food procurement in rodents
    Neil Rowland; Fiscal Year: 2008
    ..The proposed studies will be the first to address the issue of behavioral change induced by anorectics under such conditions of simulated economic costs. [unreadable] [unreadable] [unreadable]..