Robert E Rosenthal

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi request reprint Hyperbaric oxygen reduces neuronal death and improves neurological outcome after canine cardiac arrest
    Robert E Rosenthal
    Program in Trauma, Department of Surgery, University of Maryland, Baltimore, USA
    Stroke 34:1311-6. 2003
  2. ncbi request reprint Delayed therapy of experimental global cerebral ischemia with acetyl-L-carnitine in dogs
    Robert E Rosenthal
    Program in Trauma, Department of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Neurosci Lett 378:82-7. 2005
  3. pmc Normoxic resuscitation after cardiac arrest protects against hippocampal oxidative stress, metabolic dysfunction, and neuronal death
    Viktoria Vereczki
    Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Cereb Blood Flow Metab 26:821-35. 2006
  4. pmc Hyperoxic reperfusion after global ischemia decreases hippocampal energy metabolism
    Erica M Richards
    Program in Neuroscience, The Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD, USA
    Stroke 38:1578-84. 2007
  5. pmc Hyperoxic reperfusion after global cerebral ischemia promotes inflammation and long-term hippocampal neuronal death
    Julie L Hazelton
    Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Neurotrauma 27:753-62. 2010
  6. pmc Pyruvate dehydrogenase complex: metabolic link to ischemic brain injury and target of oxidative stress
    Erica Martin
    Department of Anesthesiology, University of Maryland School of Medicine, 684 W Baltimore Street, Baltimore, MD 21201, USA
    J Neurosci Res 79:240-7. 2005
  7. pmc Postischemic oxidative stress promotes mitochondrial metabolic failure in neurons and astrocytes
    Gary Fiskum
    Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Ann N Y Acad Sci 1147:129-38. 2008
  8. pmc Oximetry-guided reoxygenation improves neurological outcome after experimental cardiac arrest
    Irina S Balan
    Departments of Anesthesiology, Program in Trauma, University of Maryland School of Medicine, Baltimore, MD, USA
    Stroke 37:3008-13. 2006
  9. pmc Postischemic hyperoxia reduces hippocampal pyruvate dehydrogenase activity
    Erica M Richards
    Department of Anesthesiology, University of Maryland, Baltimore, MD 21201, USA
    Free Radic Biol Med 40:1960-70. 2006
  10. ncbi request reprint Oxygen: could there be too much of a good thing?
    Robert E Rosenthal
    Program in Trauma, The R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Hosp Med 66:76-7. 2005

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Hyperbaric oxygen reduces neuronal death and improves neurological outcome after canine cardiac arrest
    Robert E Rosenthal
    Program in Trauma, Department of Surgery, University of Maryland, Baltimore, USA
    Stroke 34:1311-6. 2003
    ....
  2. ncbi request reprint Delayed therapy of experimental global cerebral ischemia with acetyl-L-carnitine in dogs
    Robert E Rosenthal
    Program in Trauma, Department of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD 21201, USA
    Neurosci Lett 378:82-7. 2005
    ..A 30-min delay in ALCAR administration following ROSC from 10 min CA impairs the ability of this drug to promote neurologic recovery despite apparent normalization of brain lactate levels...
  3. pmc Normoxic resuscitation after cardiac arrest protects against hippocampal oxidative stress, metabolic dysfunction, and neuronal death
    Viktoria Vereczki
    Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Cereb Blood Flow Metab 26:821-35. 2006
    ..Moreover, these findings indicate the need for clinical trials comparing the effects of different ventilatory oxygen levels on neurologic outcome after cardiac arrest...
  4. pmc Hyperoxic reperfusion after global ischemia decreases hippocampal energy metabolism
    Erica M Richards
    Program in Neuroscience, The Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD, USA
    Stroke 38:1578-84. 2007
    ..Using a clinically relevant canine cardiac arrest model, in this study we tested the hypothesis that hyperoxic reperfusion decreases hippocampal glucose metabolism and glutamate synthesis...
  5. pmc Hyperoxic reperfusion after global cerebral ischemia promotes inflammation and long-term hippocampal neuronal death
    Julie L Hazelton
    Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Neurotrauma 27:753-62. 2010
    ....
  6. pmc Pyruvate dehydrogenase complex: metabolic link to ischemic brain injury and target of oxidative stress
    Erica Martin
    Department of Anesthesiology, University of Maryland School of Medicine, 684 W Baltimore Street, Baltimore, MD 21201, USA
    J Neurosci Res 79:240-7. 2005
    ....
  7. pmc Postischemic oxidative stress promotes mitochondrial metabolic failure in neurons and astrocytes
    Gary Fiskum
    Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Ann N Y Acad Sci 1147:129-38. 2008
    ..These results support the hypothesis that release and or consumption of mitochondrial NAD(H) is at least partially responsible for respiratory inhibition, particularly in neurons...
  8. pmc Oximetry-guided reoxygenation improves neurological outcome after experimental cardiac arrest
    Irina S Balan
    Departments of Anesthesiology, Program in Trauma, University of Maryland School of Medicine, Baltimore, MD, USA
    Stroke 37:3008-13. 2006
    ..This study tested the hypothesis that graded reoxygenation, with oximetry guidance, can safely reduce FiO(2) after resuscitation, avoiding hypoxia while promoting neurological recovery...
  9. pmc Postischemic hyperoxia reduces hippocampal pyruvate dehydrogenase activity
    Erica M Richards
    Department of Anesthesiology, University of Maryland, Baltimore, MD 21201, USA
    Free Radic Biol Med 40:1960-70. 2006
    ..These results support the hypothesis that oxidative stress contributes to loss of hippocampal PDHC activity during cerebral ischemia and reperfusion and suggest that PDHC is a target of peroxynitrite...
  10. ncbi request reprint Oxygen: could there be too much of a good thing?
    Robert E Rosenthal
    Program in Trauma, The R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Hosp Med 66:76-7. 2005
  11. ncbi request reprint Protection against ischemic brain injury by inhibition of mitochondrial oxidative stress
    Gary Fiskum
    Department of Anesthesiology, University of Maryland School of Medicine, 685 W Baltimore St, MSTF 5 34, Baltimore, Maryland 21201, USA
    J Bioenerg Biomembr 36:347-52. 2004
    ....
  12. ncbi request reprint The effect of hyperbaric oxygen therapy on composite graft survival
    Edward N Li
    Division of Plastic and Reconstructive Surgery, University of Maryland Medical Systems, Baltimore, MD, USA
    Ann Plast Surg 53:141-5. 2004
    ..8 +/- 15.7% compared with a survival rate of 51.31 +/- 38.5% for the control group (n = 8; P = 0.0478). There was no such benefit in smaller grafts. HBO could prove clinically useful for larger composite grafts...
  13. ncbi request reprint Ultrasound-diagnosed cardiac tamponade after blunt abdominal trauma-treated with emergent thoracotomy
    Jay Menaker
    R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Emerg Med 32:99-103. 2007
    ....
  14. ncbi request reprint Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation
    Maryla Krajewska
    The Burnham Institute, La Jolla, CA 92037, USA
    Exp Neurol 189:261-79. 2004
    ....
  15. ncbi request reprint Mechanisms of ischemic neuroprotection by acetyl-L-carnitine
    Santina A Zanelli
    Department of Pediatrics, University of Virginia School of Medicine, Charlottesville 22908, USA
    Ann N Y Acad Sci 1053:153-61. 2005
    ....
  16. ncbi request reprint Neuroprotective effects of hyperbaric oxygen treatment in experimental focal cerebral ischemia are associated with reduced brain leukocyte myeloperoxidase activity
    Milena Miljkovic-Lolic
    Department of Medicine, St Joseph Medical Center, Towson, MD, USA
    Brain Res 971:90-4. 2003
    ..We hypothesized that HBO given prior to or after MCAO reduces PMN infiltration into the brain, and that decreased PMN infiltration is associated with improved functional and anatomic outcome...