Michael D Rosenblum

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Treating human autoimmunity: current practice and future prospects
    Michael D Rosenblum
    Department of Dermatology, University of California, San Francisco, San Francisco, CA 94115, USA
    Sci Transl Med 4:125sr1. 2012
  2. pmc Response to self antigen imprints regulatory memory in tissues
    Michael D Rosenblum
    Department of Dermatology, University of California San Francisco, San Francisco, California 94115, USA
    Nature 480:538-42. 2011
  3. pmc Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues
    Iris K Gratz
    Department of Dermatology, University of California San Francisco, San Francisco, CA 94143, USA
    J Immunol 190:4483-7. 2013
  4. pmc Opposing functions of IL-2 and IL-7 in the regulation of immune responses
    Shoshana D Katzman
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143 0511, USA
    Cytokine 56:116-21. 2011

Collaborators

Detail Information

Publications4

  1. doi request reprint Treating human autoimmunity: current practice and future prospects
    Michael D Rosenblum
    Department of Dermatology, University of California, San Francisco, San Francisco, CA 94115, USA
    Sci Transl Med 4:125sr1. 2012
    ..This review discusses these advances as well as the challenges that must be overcome to target these therapies to patients suffering from autoimmune disease while avoiding the pitfalls of general immunosuppression...
  2. pmc Response to self antigen imprints regulatory memory in tissues
    Michael D Rosenblum
    Department of Dermatology, University of California San Francisco, San Francisco, California 94115, USA
    Nature 480:538-42. 2011
    ..These findings provide a framework for understanding how T(reg) cells respond when exposed to self antigen in peripheral tissues and offer mechanistic insight into how tissues regulate autoimmunity...
  3. pmc Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues
    Iris K Gratz
    Department of Dermatology, University of California San Francisco, San Francisco, CA 94143, USA
    J Immunol 190:4483-7. 2013
    ..Conversely, IL-7 is essential for maintaining mTregs in skin in the steady state. These results elucidate the fundamental biology of mTregs and show that IL-7 plays an important role in their survival in skin...
  4. pmc Opposing functions of IL-2 and IL-7 in the regulation of immune responses
    Shoshana D Katzman
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143 0511, USA
    Cytokine 56:116-21. 2011
    ..Here we discuss the opposing functions of two members of the common receptor gamma chain (γc) cytokines, IL-2 and IL-7 in the generation and regulation of immune responses in vivo...