Research Topics
Species | A L RosenbloomSummaryAffiliation: University of Florida Country: USA Publications
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Detail Information
Publications
Absence of hypoglycemia in response to varying doses of recombinant human insulin-like growth factor-I (rhIGF-I) in children and adolescents with low serum concentrations of IGF-IJaime Guevara-Aguirre
Institute for Endocrinology, Metabolism, and Reproduction, IEMYR, Institute for Endocrinology, Quito, Ecuador
Acta Paediatr 95:199-202. 2006....
Limited joint mobility in childhood diabetes: discovery, description, and declineArlan L Rosenbloom
MD, Children s Medical Services Center, 1701 SW 16th Avenue, Gainesville, Florida 32608
J Clin Endocrinol Metab 98:466-73. 2013..The prevalence of LJM in a population may serve as a measure of quality of diabetes control...
Inaccuracy of age assessment from images of postpubescent subjects in cases of alleged child pornographyArlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Children s Medical Services Center, 1701 SW 16th Ave, Gainesville, FL, 32608, USA
Int J Legal Med 127:467-71. 2013..Thus, important as prosecuting users of child pornographic material may be, justice requires the avoidance of testimony that is not scientifically based...
Tanner stage 4 breast development in adults: forensic implicationsArlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, 1701 SW 16th Ave, PO Box 100296, Gainesville, FL 32608, USA
Pediatrics 130:e978-81. 2012..Clinical experience does not support this notion, but there are no relevant studies. We sought to estimate how frequently TS 4 might be interpreted from nonclinical images by individual forensic experts...
Is there a role for recombinant insulin-like growth factor-I in the treatment of idiopathic short stature?Arlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32608, USA
Lancet 368:612-6. 2006
The role of recombinant insulin-like growth factor I in the treatment of the short childArlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
Curr Opin Pediatr 19:458-64. 2007..Off-label use has been promoted because of the paucity of patients having approved indications; I review the background and rationale for such use...
Hyperglycemic crises and their complications in childrenArlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Children s Medical Services Center, 1701 SW 16th Avenue, Gainesville 32608, USA
J Pediatr Endocrinol Metab 20:5-18. 2007..The prevention of DKA and HHS at the onset of diabetes mellitus requires a high degree of awareness and suspicion by primary care providers; prevention of recurrent DKA necessitates a diligent team effort...
Recombinant human insulin-like growth factor I (rhIGF-I) and rhIGF-I/rhIGF-binding-protein-3: new growth treatment options?Arlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
J Pediatr 150:7-11. 2007
Hyperglycemic comas in children: new insights into pathophysiology and managementArlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, College of Medicine, Children's Medical Services Center, University of Florida, 1701 SW 16th Avenue, Gainesville, 32608, USA
Rev Endocr Metab Disord 6:297-306. 2005
Controversy in clinical endocrinology: reclassification of insulin-like growth factor I production and action disordersArlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida 32608, USA
J Clin Endocrinol Metab 91:4232-4. 2006..No generally agreed-upon or consensus-derived classification exists...
Fatal cerebral infarctions in diabetic ketoacidosis in a child with previously unknown heterozygosity for factor V Leiden deficiencyArlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
J Pediatr 145:561-2. 2004..He was heterozygous for factor V Leiden deficiency. This case emphasizes the value of cranial imaging after initial resuscitative treatment of neurologic collapse in diabetic ketoacidosis...
Cerebral edema in diabetic ketoacidosis and other acute devastating complications: recent observationsArlan L Rosenbloom
Department of Pediatrics, University of Florida College of Medicine, Gainesville, Children's Medical Services Center, FL 32608, USA
Pediatr Diabetes 6:41-9. 2005
Autoimmune type 2 diabetes mellitus and rational classificationArlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
J Pediatr Endocrinol Metab 20:957-9. 2007
Insulin-like growth factor-I (rhIGF-I) therapy of short statureArlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
J Pediatr Endocrinol Metab 21:301-15. 2008....
Mecasermin (recombinant human insulin-like growth factor I)Arlan L Rosenbloom
Department of Pediatrics, University of Florida College of Medicine, Children s Medical Services Center, Gainesville, FL 32608, USA
Adv Ther 26:40-54. 2009..The anti-apoptotic properties of IGF-I are implicated in cancer pathogenesis-a concern for long-term therapy. It is unlikely that mecasermin will be useful beyond the orphan indications of severe insulin resistance and GH insensitivity...
The management of diabetic ketoacidosis in childrenArlan L Rosenbloom
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
Diabetes Ther 1:103-20. 2010..The prevention of DKA at onset of diabetes requires an informed community and high index of suspicion; prevention of recurrent DKA, which is almost always due to insulin omission, necessitates a committed team effort...
Increasing incidence of type 2 diabetes in children and adolescents: treatment considerationsArlan L Rosenbloom
Children s Medical Services Center, Gainesville, Florida 32608 1153, USA
Paediatr Drugs 4:209-21. 2002..Prevention efforts will require community and government involvement to reduce obesity and increase physical activity in the child, as well as adult, population...
Stature in Ecuadorians heterozygous for growth hormone receptor gene E180 splice mutation does not differ from that of homozygous normal relativesA L Rosenbloom
Department of Pediatrics, University of Florida College of Medicine, Gainesville 32608, USA
J Clin Endocrinol Metab 83:2373-5. 1998....
Emerging epidemic of type 2 diabetes in youthA L Rosenbloom
Children s Medical Services Center, University of Florida College of Medicine, Gainesville 32608, USA
Diabetes Care 22:345-54. 1999..S. population is increasing, presents a serious public health problem. The full effect of this epidemic will be felt as these children become adults and develop the long-term complications of diabetes...
IGF-I deficiency due to GH receptor deficiencyA L Rosenbloom
Department of Pediatrics, University of Florida, College of Medicine, Children s Medical Services Center, Gainesville, USA
Horm Metab Res 31:161-71. 1999....
Treatment of type 2 diabetes mellitus in children and adolescentsJ H Silverstein
Department of Pediatrics, University of Florida College of Medicine, Children s Medical Services Center, Gainesville 32608 1153, USA
J Pediatr Endocrinol Metab 13:1403-9. 2000..There are no studies of the efficacy or compliance with treatment for type 2 DM in adolescents. Treatment is currently based on the clinical experience with adults. Controlled clinical trials in children are essential...
Normal intelligence with severe insulin-like growth factor I deficiency due to growth hormone receptor deficiency: a controlled study in a genetically homogeneous populationJ H Kranzler
Department of Foundations of Education, University of Florida College of Education, Gainesville 32611 7047, USA
J Clin Endocrinol Metab 83:1953-8. 1998..They also indicate that GH-induced IGF-I production is not required for normal brain growth in utero or for postnatal intellectual development...
Arterial thrombosis resulting in amputation in a child with poorly controlled type 1 diabetes and heterozygous Factor V Leiden mutationMichael J Haller
Division of Pediatric Endocrinology, Department of Pediatrics, University of Florida, Gainesville, FL, USA
Pediatr Diabetes 7:229-31. 2006..This report emphasizes the need to test for thrombophilic defects in children with thrombosis or with a family history of thrombosis. Good metabolic control is especially important in children with T1DM and known thrombophilic defects...
Death caused by hyperglycemic hyperosmolar state at the onset of type 2 diabetesAlba E Morales
Division of Pediatric Endocrinology, University of Florida College of Medicine, Gainesville, Florida 32608-1153, USA
J Pediatr 144:270-3. 2004..All had previously unrecognized type 2 diabetes, and death may have been prevented with earlier diagnosis or treatment...
Changes in frequency and severity of limited joint mobility in children with type 1 diabetes mellitus between 1976-78 and 1998J R Infante
Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
J Pediatr 138:33-7. 2001..025). CONCLUSIONS: These findings confirm the hypothesis that the prevalence of LJM has decreased, most likely the result of improved blood glucose control during the past 2 decades...
Type 2 diabetes in childrenJ H Silverstein
Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, PO Box 100216, Gainesville, FL 32610 0216, USA
Curr Diab Rep 1:19-27. 2001..Community and governmental efforts to educate all children and their parents about the need for physical activity and dietary modification are essential to control this epidemic...
Clinical and biochemical phenotype of familial anterior hypopituitarism from mutation of the PROP1 geneA L Rosenbloom
Department of Pediatrics, University of Florida, Children s Medical Services Center, Gainesville 32608, USA
J Clin Endocrinol Metab 84:50-7. 1999..The severity of the hormone deficiency phenotype is compatible with the complete loss of PROP1 activity...
Type 2 diabetes mellitus among Florida children and adolescents, 1994 through 1998Christine J Macaluso
University of South Florida, Tampa, FL, USA
Public Health Rep 117:373-9. 2002..This study was undertaken to examine the trends in the diagnosis of Type 2 diabetes mellitus among children and adolescents with new-onset diabetes seen from 1994 through 1998 at the three university-based diabetes centers in Florida...
Cerebral edema in childhood diabetic ketoacidosis: natural history, radiographic findings, and early identificationAndrew B Muir
Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
Diabetes Care 27:1541-6. 2004..Our objective was to develop a model for early detection of CE in children with DKA...
Growth hormone therapy improves growth in children with cystic fibrosis related liver diseaseMichael S Stalvey
University of Florida, Department of Pediatrics, Division of Pediatric Endocrinology, Gainesville, FL, USA
J Pediatr Endocrinol Metab 21:793-7. 2008..The second patient was a 5 month-old male with advanced liver disease who had transient improved growth and liver function following rhGH. These patients suggest that rhGH is safe and may be effective in children with CFLD...
Treatment approaches for growth failureArlan L Rosenbloom
Pediatr Endocrinol Rev 6:48-50. 2008
Obesity, Insulin Resistance, beta-Cell Autoimmunity, and the Changing Clinical Epidemiology of Childhood DiabetesArlan L Rosenbloom
Diabetes Care 26:2954-6. 2003
Effects of heterozygosity for the E180 splice mutation causing growth hormone receptor deficiency in Ecuador on IGF-I, IGFBP-3, and statureJaime Guevara-Aguirre
Institute for Endocrinology Metabolism and Reproduction IEMYR, Quito, Ecuador
Growth Horm IGF Res 17:261-4. 2007....
Clinical predictors of mucormycosis in children with type 1 diabetes mellitusJulie Moye
J Pediatr Endocrinol Metab 15:1001-4. 2002..African-American race and poor compliance, as evidenced by poor clinic attendance, risk-taking behaviors and high admission rate to the DPU, were predictors of increased susceptibility to infection with mucormycosis...
Diabetes mellitus-related autoantibodies in childhood autoimmune hepatitisMaria E R da Silva
Laboratory of Medical Investigation, , Brazil
J Pediatr Endocrinol Metab 15:831-40. 2002..CONCLUSIONS: AIH in childhood is associated with high frequency of ICA and IAA, with less than expected rates of progression to DM. Immunosuppression reduced ICA and IAA frequency and titers...
Type 1 and type 2 diabetes mellitus in childhood in the United States: practice patterns by pediatric endocrinologistsRobert Rapaport
Pediatric Endocrinology and Diabetes, Mount Sinai School of Medicine, New York, NY 10029, USA
J Pediatr Endocrinol Metab 17:871-7. 2004..To determine the relative frequency of type 2 diabetes mellitus (DM) in the US, and to assess diabetes practice patterns in the US...
Hyperglycemic crises at the onset of type 2 diabetes in obese childrenArlan L Rosenbloom
Endocr Pract 12:107. 2006
Fetal nutrition and insulin sensitivity: The genetic and environmental aspects of "thrift"Arlan L Rosenbloom
J Pediatr 141:459-62. 2002
Treatment of diabetic ketoacidosis and the risk of cerebral edemaArlan L Rosenbloom
J Pediatr 152:146-7; author reply 147-9. 2008
The Endocrine Society 2003 annual awardsMaria Iandole New
Endocr Rev 24:558-69. 2003
Distinguishing type 1 and type 2 diabetes at diagnosis. What is the problem?Arlan L Rosenbloom
Pediatr Diabetes 8:51-2. 2007
The variable but inevitable loss of beta cells in overt type 1 diabetesArlan L Rosenbloom
Pediatr Diabetes 4:1-3. 2003
The journey to metabolic control in diabetes: many more miles to goJanet H Silverstein
J Pediatr 143:704-6. 2003
Implications for primary care of diabetes and impaired fasting glucose prevalence in adolescentsArlan L Rosenbloom
Arch Pediatr Adolesc Med 160:550-2. 2006
Comparison of oral insulin spray and subcutaneous regular insulin at mealtime in type 1 diabetesJaime Guevara-Aguirre
Institute for Endocrinology Metabolism and Reproduction, Quito, Ecuador
Diabetes Technol Ther 9:372-6. 2007....
