A L Rosenbloom

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi Absence of hypoglycemia in response to varying doses of recombinant human insulin-like growth factor-I (rhIGF-I) in children and adolescents with low serum concentrations of IGF-I
    Jaime Guevara-Aguirre
    Institute for Endocrinology, Metabolism, and Reproduction, IEMYR, Institute for Endocrinology, Quito, Ecuador
    Acta Paediatr 95:199-202. 2006
  2. pmc Idiopathic short stature: conundrums of definition and treatment
    Arlan L Rosenbloom
    Department of Pediatrics, Children s Medical Services Center, University of Florida College of Medicine, 1701 SW 16th Ave, Gainesville, FL 32608, USA
    Int J Pediatr Endocrinol 2009:470378. 2009
  3. doi Sudden death of a young woman attributed to diabetic ketoacidosis
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, United States Electronic address
    J Forensic Leg Med 20:1063-5. 2013
  4. doi Limited joint mobility in childhood diabetes: discovery, description, and decline
    Arlan L Rosenbloom
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida 32608, USA
    J Clin Endocrinol Metab 98:466-73. 2013
  5. doi Inaccuracy of age assessment from images of postpubescent subjects in cases of alleged child pornography
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Children s Medical Services Center, 1701 SW 16th Ave, Gainesville, FL 32608, USA
    Int J Legal Med 127:467-71. 2013
  6. doi Tanner stage 4 breast development in adults: forensic implications
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, 1701 SW 16th Ave, PO Box 100296, Gainesville, FL 32608, USA
    Pediatrics 130:e978-81. 2012
  7. ncbi Hyperglycemic comas in children: new insights into pathophysiology and management
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, College of Medicine, Children s Medical Services Center, University of Florida, 1701 SW 16th Avenue, Gainesville, 32608, USA
    Rev Endocr Metab Disord 6:297-306. 2005
  8. ncbi Recombinant human insulin-like growth factor I (rhIGF-I) and rhIGF-I/rhIGF-binding-protein-3: new growth treatment options?
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
    J Pediatr 150:7-11. 2007
  9. ncbi Cerebral edema in diabetic ketoacidosis and other acute devastating complications: recent observations
    Arlan L Rosenbloom
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, Children s Medical Services Center, FL 32608, USA
    Pediatr Diabetes 6:41-9. 2005
  10. ncbi Hyperglycemic crises and their complications in children
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Children s Medical Services Center, 1701 SW 16th Avenue, Gainesville 32608, USA
    J Pediatr Endocrinol Metab 20:5-18. 2007

Collaborators

Detail Information

Publications50

  1. ncbi Absence of hypoglycemia in response to varying doses of recombinant human insulin-like growth factor-I (rhIGF-I) in children and adolescents with low serum concentrations of IGF-I
    Jaime Guevara-Aguirre
    Institute for Endocrinology, Metabolism, and Reproduction, IEMYR, Institute for Endocrinology, Quito, Ecuador
    Acta Paediatr 95:199-202. 2006
    ....
  2. pmc Idiopathic short stature: conundrums of definition and treatment
    Arlan L Rosenbloom
    Department of Pediatrics, Children s Medical Services Center, University of Florida College of Medicine, 1701 SW 16th Ave, Gainesville, FL 32608, USA
    Int J Pediatr Endocrinol 2009:470378. 2009
    ..This report further emphasizes the importance of discouraging the expectation that taller stature from GH treatment will improve quality of life...
  3. doi Sudden death of a young woman attributed to diabetic ketoacidosis
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, United States Electronic address
    J Forensic Leg Med 20:1063-5. 2013
    ..More thorough tissue study of the heart and analysis of the circumstances led to a credible explanation of the entire scenario. ..
  4. doi Limited joint mobility in childhood diabetes: discovery, description, and decline
    Arlan L Rosenbloom
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida 32608, USA
    J Clin Endocrinol Metab 98:466-73. 2013
    ..The discovery of limited joint mobility (LJM) as the earliest clinically apparent complication of diabetes in children and adolescents nearly 40 years ago provided insights into the mechanism of diabetes complications...
  5. doi Inaccuracy of age assessment from images of postpubescent subjects in cases of alleged child pornography
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Children s Medical Services Center, 1701 SW 16th Ave, Gainesville, FL 32608, USA
    Int J Legal Med 127:467-71. 2013
    ..Thus, important as prosecuting users of child pornographic material may be, justice requires the avoidance of testimony that is not scientifically based...
  6. doi Tanner stage 4 breast development in adults: forensic implications
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, 1701 SW 16th Ave, PO Box 100296, Gainesville, FL 32608, USA
    Pediatrics 130:e978-81. 2012
    ..Clinical experience does not support this notion, but there are no relevant studies. We sought to estimate how frequently TS 4 might be interpreted from nonclinical images by individual forensic experts...
  7. ncbi Hyperglycemic comas in children: new insights into pathophysiology and management
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, College of Medicine, Children s Medical Services Center, University of Florida, 1701 SW 16th Avenue, Gainesville, 32608, USA
    Rev Endocr Metab Disord 6:297-306. 2005
  8. ncbi Recombinant human insulin-like growth factor I (rhIGF-I) and rhIGF-I/rhIGF-binding-protein-3: new growth treatment options?
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
    J Pediatr 150:7-11. 2007
  9. ncbi Cerebral edema in diabetic ketoacidosis and other acute devastating complications: recent observations
    Arlan L Rosenbloom
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, Children s Medical Services Center, FL 32608, USA
    Pediatr Diabetes 6:41-9. 2005
  10. ncbi Hyperglycemic crises and their complications in children
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Children s Medical Services Center, 1701 SW 16th Avenue, Gainesville 32608, USA
    J Pediatr Endocrinol Metab 20:5-18. 2007
    ..The prevention of DKA and HHS at the onset of diabetes mellitus requires a high degree of awareness and suspicion by primary care providers; prevention of recurrent DKA necessitates a diligent team effort...
  11. ncbi The role of recombinant insulin-like growth factor I in the treatment of the short child
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
    Curr Opin Pediatr 19:458-64. 2007
    ..Off-label use has been promoted because of the paucity of patients having approved indications; I review the background and rationale for such use...
  12. ncbi Controversy in clinical endocrinology: reclassification of insulin-like growth factor I production and action disorders
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida 32608, USA
    J Clin Endocrinol Metab 91:4232-4. 2006
    ..No generally agreed-upon or consensus-derived classification exists...
  13. ncbi Autoimmune type 2 diabetes mellitus and rational classification
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    J Pediatr Endocrinol Metab 20:957-9. 2007
  14. ncbi Fatal cerebral infarctions in diabetic ketoacidosis in a child with previously unknown heterozygosity for factor V Leiden deficiency
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
    J Pediatr 145:561-2. 2004
    ..He was heterozygous for factor V Leiden deficiency. This case emphasizes the value of cranial imaging after initial resuscitative treatment of neurologic collapse in diabetic ketoacidosis...
  15. doi Mecasermin (recombinant human insulin-like growth factor I)
    Arlan L Rosenbloom
    Department of Pediatrics, University of Florida College of Medicine, Children s Medical Services Center, Gainesville, FL 32608, USA
    Adv Ther 26:40-54. 2009
    ..The anti-apoptotic properties of IGF-I are implicated in cancer pathogenesis-a concern for long-term therapy. It is unlikely that mecasermin will be useful beyond the orphan indications of severe insulin resistance and GH insensitivity...
  16. ncbi Is there a role for recombinant insulin-like growth factor-I in the treatment of idiopathic short stature?
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32608, USA
    Lancet 368:612-6. 2006
  17. pmc The management of diabetic ketoacidosis in children
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
    Diabetes Ther 1:103-20. 2010
    ..The prevention of DKA at onset of diabetes requires an informed community and high index of suspicion; prevention of recurrent DKA, which is almost always due to insulin omission, necessitates a committed team effort...
  18. ncbi Increasing incidence of type 2 diabetes in children and adolescents: treatment considerations
    Arlan L Rosenbloom
    Children s Medical Services Center, Gainesville, Florida 32608 1153, USA
    Paediatr Drugs 4:209-21. 2002
    ..Prevention efforts will require community and government involvement to reduce obesity and increase physical activity in the child, as well as adult, population...
  19. ncbi Emerging epidemic of type 2 diabetes in youth
    A L Rosenbloom
    Children s Medical Services Center, University of Florida College of Medicine, Gainesville 32608, USA
    Diabetes Care 22:345-54. 1999
    ..S. population is increasing, presents a serious public health problem. The full effect of this epidemic will be felt as these children become adults and develop the long-term complications of diabetes...
  20. ncbi IGF-I deficiency due to GH receptor deficiency
    A L Rosenbloom
    Department of Pediatrics, University of Florida, College of Medicine, Children s Medical Services Center, Gainesville, USA
    Horm Metab Res 31:161-71. 1999
    ....
  21. ncbi Insulin-like growth factor-I (rhIGF-I) therapy of short stature
    Arlan L Rosenbloom
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA
    J Pediatr Endocrinol Metab 21:301-15. 2008
    ....
  22. ncbi Stature in Ecuadorians heterozygous for growth hormone receptor gene E180 splice mutation does not differ from that of homozygous normal relatives
    A L Rosenbloom
    Department of Pediatrics, University of Florida College of Medicine, Gainesville 32608, USA
    J Clin Endocrinol Metab 83:2373-5. 1998
    ....
  23. ncbi Treatment of type 2 diabetes mellitus in children and adolescents
    J H Silverstein
    Department of Pediatrics, University of Florida College of Medicine, Children s Medical Services Center, Gainesville 32608 1153, USA
    J Pediatr Endocrinol Metab 13:1403-9. 2000
    ..There are no studies of the efficacy or compliance with treatment for type 2 DM in adolescents. Treatment is currently based on the clinical experience with adults. Controlled clinical trials in children are essential...
  24. ncbi Normal intelligence with severe insulin-like growth factor I deficiency due to growth hormone receptor deficiency: a controlled study in a genetically homogeneous population
    J H Kranzler
    Department of Foundations of Education, University of Florida College of Education, Gainesville 32611 7047, USA
    J Clin Endocrinol Metab 83:1953-8. 1998
    ..They also indicate that GH-induced IGF-I production is not required for normal brain growth in utero or for postnatal intellectual development...
  25. ncbi Arterial thrombosis resulting in amputation in a child with poorly controlled type 1 diabetes and heterozygous Factor V Leiden mutation
    Michael J Haller
    Division of Pediatric Endocrinology, Department of Pediatrics, University of Florida, Gainesville, FL, USA
    Pediatr Diabetes 7:229-31. 2006
    ..This report emphasizes the need to test for thrombophilic defects in children with thrombosis or with a family history of thrombosis. Good metabolic control is especially important in children with T1DM and known thrombophilic defects...
  26. ncbi Changes in frequency and severity of limited joint mobility in children with type 1 diabetes mellitus between 1976-78 and 1998
    J R Infante
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
    J Pediatr 138:33-7. 2001
    ..025). CONCLUSIONS: These findings confirm the hypothesis that the prevalence of LJM has decreased, most likely the result of improved blood glucose control during the past 2 decades...
  27. ncbi Death caused by hyperglycemic hyperosmolar state at the onset of type 2 diabetes
    Alba E Morales
    Division of Pediatric Endocrinology, University of Florida College of Medicine, Gainesville, Florida 32608 1153, USA
    J Pediatr 144:270-3. 2004
    ..All had previously unrecognized type 2 diabetes, and death may have been prevented with earlier diagnosis or treatment...
  28. ncbi Type 2 diabetes in children
    J H Silverstein
    Division of Endocrinology, Department of Pediatrics, University of Florida College of Medicine, PO Box 100216, Gainesville, FL 32610 0216, USA
    Curr Diab Rep 1:19-27. 2001
    ..Community and governmental efforts to educate all children and their parents about the need for physical activity and dietary modification are essential to control this epidemic...
  29. ncbi Clinical and biochemical phenotype of familial anterior hypopituitarism from mutation of the PROP1 gene
    A L Rosenbloom
    Department of Pediatrics, University of Florida, Children s Medical Services Center, Gainesville 32608, USA
    J Clin Endocrinol Metab 84:50-7. 1999
    ..The severity of the hormone deficiency phenotype is compatible with the complete loss of PROP1 activity...
  30. pmc Type 2 diabetes mellitus among Florida children and adolescents, 1994 through 1998
    Christine J Macaluso
    University of South Florida, Tampa, FL, USA
    Public Health Rep 117:373-9. 2002
    ..This study was undertaken to examine the trends in the diagnosis of Type 2 diabetes mellitus among children and adolescents with new-onset diabetes seen from 1994 through 1998 at the three university-based diabetes centers in Florida...
  31. ncbi Cerebral edema in childhood diabetic ketoacidosis: natural history, radiographic findings, and early identification
    Andrew B Muir
    Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida, USA
    Diabetes Care 27:1541-6. 2004
    ..Our objective was to develop a model for early detection of CE in children with DKA...
  32. ncbi Growth hormone therapy improves growth in children with cystic fibrosis related liver disease
    Michael S Stalvey
    University of Florida, Department of Pediatrics, Division of Pediatric Endocrinology, Gainesville, FL, USA
    J Pediatr Endocrinol Metab 21:793-7. 2008
    ..The second patient was a 5 month-old male with advanced liver disease who had transient improved growth and liver function following rhGH. These patients suggest that rhGH is safe and may be effective in children with CFLD...
  33. ncbi Clinical predictors of mucormycosis in children with type 1 diabetes mellitus
    Julie Moye
    J Pediatr Endocrinol Metab 15:1001-4. 2002
    ..Despite the importance of this condition, the clinical predictors of mucor infection are not well defined...
  34. ncbi Effects of heterozygosity for the E180 splice mutation causing growth hormone receptor deficiency in Ecuador on IGF-I, IGFBP-3, and stature
    Jaime Guevara-Aguirre
    Institute for Endocrinology Metabolism and Reproduction IEMYR, Quito, Ecuador
    Growth Horm IGF Res 17:261-4. 2007
    ....
  35. ncbi Diabetes mellitus-related autoantibodies in childhood autoimmune hepatitis
    Maria E R da Silva
    Laboratory of Medical Investigation, Sao Paulo Medical School, Brazil
    J Pediatr Endocrinol Metab 15:831-40. 2002
    ..To determine the frequency and significance of diabetes mellitus (DM)-related autoantibodies in children with autoimmune hepatitis (AIH)...
  36. ncbi Obesity, Insulin Resistance, beta-Cell Autoimmunity, and the Changing Clinical Epidemiology of Childhood Diabetes
    Arlan L Rosenbloom
    Diabetes Care 26:2954-6. 2003
  37. ncbi Treatment approaches for growth failure
    Arlan L Rosenbloom
    Pediatr Endocrinol Rev 6:48-50. 2008
  38. ncbi Hyperglycemic crises at the onset of type 2 diabetes in obese children
    Arlan L Rosenbloom
    Endocr Pract 12:107. 2006
  39. ncbi Type 1 and type 2 diabetes mellitus in childhood in the United States: practice patterns by pediatric endocrinologists
    Robert Rapaport
    Pediatric Endocrinology and Diabetes, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Pediatr Endocrinol Metab 17:871-7. 2004
    ..To determine the relative frequency of type 2 diabetes mellitus (DM) in the US, and to assess diabetes practice patterns in the US...
  40. ncbi Implications for primary care of diabetes and impaired fasting glucose prevalence in adolescents
    Arlan L Rosenbloom
    Arch Pediatr Adolesc Med 160:550-2. 2006
  41. ncbi Fetal nutrition and insulin sensitivity: The genetic and environmental aspects of "thrift"
    Arlan L Rosenbloom
    J Pediatr 141:459-62. 2002
  42. ncbi Distinguishing type 1 and type 2 diabetes at diagnosis. What is the problem?
    Arlan L Rosenbloom
    Pediatr Diabetes 8:51-2. 2007
  43. ncbi Comparison of oral insulin spray and subcutaneous regular insulin at mealtime in type 1 diabetes
    Jaime Guevara-Aguirre
    Institute for Endocrinology Metabolism and Reproduction, Quito, Ecuador
    Diabetes Technol Ther 9:372-6. 2007
    ....
  44. ncbi The journey to metabolic control in diabetes: many more miles to go
    Janet H Silverstein
    J Pediatr 143:704-6. 2003
  45. ncbi Treatment of diabetic ketoacidosis and the risk of cerebral edema
    Arlan L Rosenbloom
    J Pediatr 152:146-7; author reply 147-9. 2008
  46. ncbi The variable but inevitable loss of beta cells in overt type 1 diabetes
    Arlan L Rosenbloom
    Pediatr Diabetes 4:1-3. 2003