Mark A Rosen

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Dynamic contrast-enhanced magnetic resonance imaging for assessing tumor vascularity and vascular effects of targeted therapies in renal cell carcinoma
    Mark A Rosen
    Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Clin Cancer Res 13:770s-776s. 2007
  2. doi request reprint MRI assessment of early tumor response in metastatic renal cell carcinoma patients treated with sorafenib
    Hyunseon Christine Kang
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    AJR Am J Roentgenol 200:120-6. 2013
  3. pmc Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapy
    David R Busch
    Dept of Physics and Astronomy, University of Pennsylvania, 209 S 33rd St, Philadelphia, PA 19104 USA
    Biomed Opt Express 4:105-21. 2013
  4. pmc Computer aided automatic detection of malignant lesions in diffuse optical mammography
    David R Busch
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Med Phys 37:1840-9. 2010
  5. ncbi request reprint Automatic coil selection for streak artifact reduction in radial MRI
    Yiqun Xue
    Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Magn Reson Med 67:470-6. 2012
  6. pmc A multichannel Markov random field framework for tumor segmentation with an application to classification of gene expression-based breast cancer recurrence risk
    Ahmed B Ashraf
    Computational Breast Imaging Group, Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    IEEE Trans Med Imaging 32:637-48. 2013
  7. ncbi request reprint Blood Flow Reduction in Breast Tissue due to Mammographic Compression
    David R Busch
    Division of Neurology, Children s Hospital of Philadelphia, Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, 19104 Electronic address
    Acad Radiol 21:151-61. 2014
  8. ncbi request reprint Pilot study of DCE-MRI to predict progression-free survival with sorafenib therapy in renal cell carcinoma
    Keith T Flaherty
    Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Cancer Biol Ther 7:496-501. 2008
  9. ncbi request reprint Automatic correction of in-plane bulk motion artifacts in self-navigated radial MRI
    Sungheon Kim
    Department of Radiology, Molecular Imaging Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA
    Magn Reson Imaging 26:367-78. 2008
  10. pmc Frequency of malignancy seen in probably benign lesions at contrast-enhanced breast MR imaging: findings from ACRIN 6667
    Susan P Weinstein
    Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce St, 1 Silverstein Building, Philadelphia, PA 19104, USA
    Radiology 255:731-7. 2010

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Dynamic contrast-enhanced magnetic resonance imaging for assessing tumor vascularity and vascular effects of targeted therapies in renal cell carcinoma
    Mark A Rosen
    Department of Radiology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Clin Cancer Res 13:770s-776s. 2007
    ..DCE-MRI can be used to monitor the vascular changes induced by such therapies. Future efforts must be directed to standardizing image acquisition and analysis techniques to quantify tumor vascular responses...
  2. doi request reprint MRI assessment of early tumor response in metastatic renal cell carcinoma patients treated with sorafenib
    Hyunseon Christine Kang
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    AJR Am J Roentgenol 200:120-6. 2013
    ..The purpose of this study was to examine early MRI changes in renal cell carcinoma (RCC) treated with the antiangiogenic agent sorafenib and to identify MRI biomarkers of RCC response to sorafenib...
  3. pmc Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapy
    David R Busch
    Dept of Physics and Astronomy, University of Pennsylvania, 209 S 33rd St, Philadelphia, PA 19104 USA
    Biomed Opt Express 4:105-21. 2013
    ..Though preliminary, the study shows how to use the malignancy parameter for separating responders from partial-responders and demonstrates the potential utility of the methodology compared to traditional DOT quantification schemes...
  4. pmc Computer aided automatic detection of malignant lesions in diffuse optical mammography
    David R Busch
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Med Phys 37:1840-9. 2010
    ..The methodology is tested in a population of 35 biopsy-confirmed malignant lesions...
  5. ncbi request reprint Automatic coil selection for streak artifact reduction in radial MRI
    Yiqun Xue
    Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Magn Reson Med 67:470-6. 2012
    ..The results demonstrate that the proposed strategy substantially improves the image quality and show excellent agreement with images reconstructed with manually determined coil selection...
  6. pmc A multichannel Markov random field framework for tumor segmentation with an application to classification of gene expression-based breast cancer recurrence risk
    Ahmed B Ashraf
    Computational Breast Imaging Group, Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    IEEE Trans Med Imaging 32:637-48. 2013
    ..88 as compared to 0.79, 0.76, 0.75, and 0.66 when using normalized cuts, single channel MRF, FCM, and FCM-VES, respectively, for segmentation...
  7. ncbi request reprint Blood Flow Reduction in Breast Tissue due to Mammographic Compression
    David R Busch
    Division of Neurology, Children s Hospital of Philadelphia, Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, 19104 Electronic address
    Acad Radiol 21:151-61. 2014
    ..Because many breast-imaging technologies derive contrast from the deformed breast, these load-dependent vascular responses affect contrast agent-enhanced and hemoglobin-based breast imaging...
  8. ncbi request reprint Pilot study of DCE-MRI to predict progression-free survival with sorafenib therapy in renal cell carcinoma
    Keith T Flaherty
    Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Cancer Biol Ther 7:496-501. 2008
    ..Sorafenib is a novel RAF and VEGF receptor tyrosine kinase inhibitor. We conducted this study to (a) determine if sorafenib is anti-angiogenic, and (b) to relate anti-angiogenic effect to outcome...
  9. ncbi request reprint Automatic correction of in-plane bulk motion artifacts in self-navigated radial MRI
    Sungheon Kim
    Department of Radiology, Molecular Imaging Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA
    Magn Reson Imaging 26:367-78. 2008
    ..Substantial motion correction with relative error of less than 5% was achieved by using either first- or second-order model with the image metrics. This study demonstrates the potential of the method for motion-sensitive applications...
  10. pmc Frequency of malignancy seen in probably benign lesions at contrast-enhanced breast MR imaging: findings from ACRIN 6667
    Susan P Weinstein
    Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce St, 1 Silverstein Building, Philadelphia, PA 19104, USA
    Radiology 255:731-7. 2010
    ....
  11. doi request reprint Respiratory motion-compensated radial dynamic contrast-enhanced (DCE)-MRI of chest and abdominal lesions
    Wei Lin
    Department of Radiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    Magn Reson Med 60:1135-46. 2008
    ..The performance of the proposed radial DCE-MRI technique is evaluated in subjects with lung and liver lesions, and results demonstrate that excellent pixelwise perfusion maps can be obtained with the proposed methodology...
  12. ncbi request reprint Computerized image analysis for identifying triple-negative breast cancers and differentiating them from other molecular subtypes of breast cancer on dynamic contrast-enhanced MR images: a feasibility study
    Shannon C Agner
    From the Department of Biomedical Engineering, Rutgers University, 599 Taylor Rd, Room 213, Piscataway, NJ 08854 S C A Departments of Radiology M A R, S E, M D S and Pathology M D F, P Z, C M, University of Pennsylvania, Philadelphia, Pa Department of Pathology and Anatomical Science, State University of New York at the University at Buffalo, Buffalo, NY J E T and Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio A M
    Radiology 272:91-9. 2014
    ....
  13. doi request reprint Non-invasive assessment of tumor neovasculature: techniques and clinical applications
    Rodolfo Perini
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Cancer Metastasis Rev 27:615-30. 2008
    ....
  14. ncbi request reprint Breast reconstruction with a transverse rectus abdominis myocutaneous flap: spectrum of normal and abnormal MR imaging findings
    Ronit Karpati Devon
    Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
    Radiographics 24:1287-99. 2004
    ..MR imaging allows differentiation between benign and malignant findings in patients with palpable abnormalities or pain after TRAM flap reconstruction...
  15. ncbi request reprint Diffuse optical tomography of breast cancer during neoadjuvant chemotherapy: a case study with comparison to MRI
    Regine Choe
    Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, Pennsylvania 19104 6396, USA
    Med Phys 32:1128-39. 2005
    ..A decrease in total hemoglobin concentration contrast between tumor and normal tissue was also observed over time. The results demonstrate the potential of DOT for measuring physiological parameters of breast lesions during chemotherapy...
  16. pmc Locally advanced breast cancer: MR imaging for prediction of response to neoadjuvant chemotherapy--results from ACRIN 6657/I-SPY TRIAL
    Nola M Hylton
    Department of Radiology, University of California, San Francisco, 1600 Divisadero St, C250, Box 1667, San Francisco, CA 94115, USA
    Radiology 263:663-72. 2012
    ..To compare magnetic resonance (MR) imaging findings and clinical assessment for prediction of pathologic response to neoadjuvant chemotherapy (NACT) in patients with stage II or III breast cancer...
  17. pmc Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography
    Regine Choe
    University of Pennsylvania, Department of Physics, 209 S 33rd Street, Philadelphia, Pennsylvania 19104, USA
    J Biomed Opt 14:024020. 2009
    ..90 to 0.99, suggesting good discriminatory power. The data demonstrate that benign and malignant lesions can be distinguished by quantitative three-dimensional DOT...
  18. ncbi request reprint Transcytolemmal water exchange in pharmacokinetic analysis of dynamic contrast-enhanced MRI data in squamous cell carcinoma of the head and neck
    Sungheon Kim
    Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Magn Reson Imaging 26:1607-17. 2007
    ..To investigate the effect of transcytolemmal water exchange on the dynamic contrast-enhanced (DCE) T(1)-weighted MRI of human squamous cell carcinomas of the head and neck (HNSCC)...
  19. ncbi request reprint High frame-rate simultaneous bilateral breast DCE-MRI
    Lawrence Dougherty
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Magn Reson Med 57:220-5. 2007
    ..In 11 of these cases there was a significant finding in the contralateral breast. DCE images of both breasts can be acquired simultaneously, resulting in high-resolution images as well as rapid sampling of the contrast kinetics...
  20. ncbi request reprint Gadolinium susceptibility artifact causing false positive stenosis isolated to the proximal common carotid artery in 3D dynamic contrast medium enhanced MR angiography of the thorax--a brief review of causes and prevention
    A Temel Tirkes
    Department of Radiology, Hospital of University of Pennsylvania, 3400 Spruce Street, 1st Floor Founders MRI Learning Center, Philadelphia, PA 19104 4283, USA
    Int J Cardiovasc Imaging 19:151-5. 2003
    ..The cause of the artifact, its identification and prevention is reviewed...
  21. doi request reprint Endorectal T2-weighted MRI does not differentiate between favorable and adverse pathologic features in men with prostate cancer who would qualify for active surveillance
    Thomas J Guzzo
    Department of Surgery, Division of Urology, The Hospital of University of Pennsylvania, Philadelphia, PA, USA
    Urol Oncol 30:301-5. 2012
    ..The goal of our study was to evaluate the ability of endorectal MRI (eMRI) to predict adverse pathologic features in patients who would otherwise qualify for an AS program...
  22. ncbi request reprint Prostate MR imaging at 3T with a longitudinal array endorectal surface coil and phased array body coil
    David Y Kim
    Department of Radiology, Weill Cornell Medical College, New York, New York, USA
    J Magn Reson Imaging 27:1327-30. 2008
    ..To demonstrate the feasibility of using a double loop phased array endorectal coil combined with a phased array body coil to image the prostate at 3T...
  23. ncbi request reprint US MR imaging correlation in pathologic conditions of the scrotum
    Woojin Kim
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Radiographics 27:1239-53. 2007
    ..Finally, MR imaging can demonstrate an intraabdominal undescended testis, which can be difficult to detect with US, and is superior to US in differentiation between an undescended testis and testicular agenesis...
  24. ncbi request reprint Innovations and challenges in renal cell carcinoma: summary statement from the Second Cambridge Conference
    Michael B Atkins
    Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Clin Cancer Res 13:667s-670s. 2007
    ....
  25. ncbi request reprint Ejaculatory function in stage T1 nonseminomatous germ cell tumors: retroperitoneal lymph node dissection versus surveillance--a decision analysis
    Peter Langenstroer
    University of Kansas Medical Center, Kansas City, USA
    J Urol 168:1396-401. 2002
    ....