Warren E Rose

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. doi request reprint New pharmacological treatments for methicillin-resistant Staphylococcus aureus infections
    Stuart L Burke
    University of Wisconsin, Madison School of Pharmacy, Pharmacy Practice Division, 777 Highland Avenue, Madison, WI 53705, USA 1 608 890 1917 1 608 265 5421
    Expert Opin Pharmacother 15:483-91. 2014
  2. doi request reprint Elevated serum interleukin-10 at time of hospital admission is predictive of mortality in patients with Staphylococcus aureus bacteremia
    Warren E Rose
    School of Pharmacy, University of Wisconsin, Madison, WI 53705, USA
    J Infect Dis 206:1604-11. 2012
  3. pmc Relationship of in vitro synergy and treatment outcome with daptomycin plus rifampin in patients with invasive methicillin-resistant Staphylococcus aureus infections
    Warren E Rose
    Pharmacy Practice Division, University of Wisconsin Madison School of Pharmacy, Madison, Wisconsin, USA
    Antimicrob Agents Chemother 57:3450-2. 2013
  4. pmc Vancomycin tolerance in methicillin-resistant Staphylococcus aureus: influence of vancomycin, daptomycin, and telavancin on differential resistance gene expression
    Warren E Rose
    Pharmacy Practice Division, University of Wisconsin Madison School of Pharmacy, Madison, Wisconsin, USA
    Antimicrob Agents Chemother 56:4422-7. 2012
  5. pmc Addition of ceftaroline to daptomycin after emergence of daptomycin-nonsusceptible Staphylococcus aureus during therapy improves antibacterial activity
    Warren E Rose
    Pharmacy Practice Division, University of Wisconsin Madison School of Pharmacy, USA
    Antimicrob Agents Chemother 56:5296-302. 2012
  6. doi request reprint Pharmacodynamic effect of clinical vancomycin exposures on cell wall thickness in heterogeneous vancomycin-intermediate Staphylococcus aureus
    Warren E Rose
    Pharmacy Practice Division, School of Pharmacy, University of Wisconsin, Madison, WI 53705, USA
    J Antimicrob Chemother 65:2149-54. 2010
  7. doi request reprint Impact of biofilm on the in vitro activity of vancomycin alone and in combination with tigecycline and rifampicin against Staphylococcus aureus
    Warren E Rose
    Pharmacy Practice Division, School of Pharmacy, University of Wisconsin, Madison, WI 53705, USA
    J Antimicrob Chemother 63:485-8. 2009
  8. pmc Fosfomycin synergy in vitro with amoxicillin, daptomycin, and linezolid against vancomycin-resistant Enterococcus faecium from renal transplant patients with infected urinary stents
    Jillian L Descourouez
    Pharmacy Practice Division, University of Wisconsin School of Pharmacy, Madison, WI, USA
    Antimicrob Agents Chemother 57:1518-20. 2013
  9. pmc Simulated antibiotic exposures in an in vitro hollow-fiber infection model influence toxin gene expression and production in community-associated methicillin-resistant Staphylococcus aureus strain MW2
    Solen Pichereau
    Pharmacy Practice Division, School of Pharmacy, University of Wisconsin, Madison, Wisconsin, USA
    Antimicrob Agents Chemother 56:140-7. 2012
  10. doi request reprint Concentration-dependent effects of antimicrobials on Staphylococcus aureus toxin-mediated cytokine production from peripheral blood mononuclear cells
    Solen Pichereau
    Pharmacy Practice Division, University of Wisconsin Madison School of Pharmacy, Madison, WI 53705, USA
    J Antimicrob Chemother 67:123-9. 2012

Collaborators

Detail Information

Publications13

  1. doi request reprint New pharmacological treatments for methicillin-resistant Staphylococcus aureus infections
    Stuart L Burke
    University of Wisconsin, Madison School of Pharmacy, Pharmacy Practice Division, 777 Highland Avenue, Madison, WI 53705, USA 1 608 890 1917 1 608 265 5421
    Expert Opin Pharmacother 15:483-91. 2014
    ..Ideally, these new agents would be rapidly bactericidal for bloodstream clearance in septic patients, have few toxicities, be active against MRSA in biofilms, be easy to administer, and have oral bioavailability...
  2. doi request reprint Elevated serum interleukin-10 at time of hospital admission is predictive of mortality in patients with Staphylococcus aureus bacteremia
    Warren E Rose
    School of Pharmacy, University of Wisconsin, Madison, WI 53705, USA
    J Infect Dis 206:1604-11. 2012
    ..We examined the predictive value of serum concentrations of interleukin (IL)-10, proinflammatory cytokines, and terminal complement on patient survival and SaB duration...
  3. pmc Relationship of in vitro synergy and treatment outcome with daptomycin plus rifampin in patients with invasive methicillin-resistant Staphylococcus aureus infections
    Warren E Rose
    Pharmacy Practice Division, University of Wisconsin Madison School of Pharmacy, Madison, Wisconsin, USA
    Antimicrob Agents Chemother 57:3450-2. 2013
    ..045). No relationship was observed between synergy and outcome by time-kill assessment. Checkerboard synergy may predict clinical response to daptomycin plus rifampin for complex invasive MRSA infections requiring prolonged treatment...
  4. pmc Vancomycin tolerance in methicillin-resistant Staphylococcus aureus: influence of vancomycin, daptomycin, and telavancin on differential resistance gene expression
    Warren E Rose
    Pharmacy Practice Division, University of Wisconsin Madison School of Pharmacy, Madison, Wisconsin, USA
    Antimicrob Agents Chemother 56:4422-7. 2012
    ....
  5. pmc Addition of ceftaroline to daptomycin after emergence of daptomycin-nonsusceptible Staphylococcus aureus during therapy improves antibacterial activity
    Warren E Rose
    Pharmacy Practice Division, University of Wisconsin Madison School of Pharmacy, USA
    Antimicrob Agents Chemother 56:5296-302. 2012
    ..Ceftaroline combined with daptomycin was effective in eliminating daptomycin-resistant MRSA, and these results further justify the potential use of daptomycin plus beta-lactam therapy for these refractory infections...
  6. doi request reprint Pharmacodynamic effect of clinical vancomycin exposures on cell wall thickness in heterogeneous vancomycin-intermediate Staphylococcus aureus
    Warren E Rose
    Pharmacy Practice Division, School of Pharmacy, University of Wisconsin, Madison, WI 53705, USA
    J Antimicrob Chemother 65:2149-54. 2010
    ..This study investigates the impact of clinical vancomycin dose simulations on cell wall thickness (CWT) and the emergence of resistance in hVISA in an in vitro pharmacodynamic model...
  7. doi request reprint Impact of biofilm on the in vitro activity of vancomycin alone and in combination with tigecycline and rifampicin against Staphylococcus aureus
    Warren E Rose
    Pharmacy Practice Division, School of Pharmacy, University of Wisconsin, Madison, WI 53705, USA
    J Antimicrob Chemother 63:485-8. 2009
    ..This study evaluated vancomycin susceptibility and activity alone and in combination with rifampicin and tigecycline against low-biofilm- and high-biofilm-producing methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates...
  8. pmc Fosfomycin synergy in vitro with amoxicillin, daptomycin, and linezolid against vancomycin-resistant Enterococcus faecium from renal transplant patients with infected urinary stents
    Jillian L Descourouez
    Pharmacy Practice Division, University of Wisconsin School of Pharmacy, Madison, WI, USA
    Antimicrob Agents Chemother 57:1518-20. 2013
    ..8 to 3.9 log(10) CFU/ml kill; P < 0.001) or amoxicillin (2.6 to 3.4; P < 0.05). These combinations may be potent options to treat VRE urinary infections pending investigation of clinical efficacy...
  9. pmc Simulated antibiotic exposures in an in vitro hollow-fiber infection model influence toxin gene expression and production in community-associated methicillin-resistant Staphylococcus aureus strain MW2
    Solen Pichereau
    Pharmacy Practice Division, School of Pharmacy, University of Wisconsin, Madison, Wisconsin, USA
    Antimicrob Agents Chemother 56:140-7. 2012
    ..SXT had minimal effects on toxin gene regulation, but it increased production and cytotoxicity of PVL toxin in the model and may enhance virulence when it is used to treat severe infections...
  10. doi request reprint Concentration-dependent effects of antimicrobials on Staphylococcus aureus toxin-mediated cytokine production from peripheral blood mononuclear cells
    Solen Pichereau
    Pharmacy Practice Division, University of Wisconsin Madison School of Pharmacy, Madison, WI 53705, USA
    J Antimicrob Chemother 67:123-9. 2012
    ..This study evaluated the impact of anti-staphylococcal antibiotic exposures over an increasing concentration range on cytokine production from peripheral blood mononuclear cells (PBMCs) after S. aureus toxin exposures...
  11. pmc β-Lactam antibiotics targeting PBP1 selectively enhance daptomycin activity against methicillin-resistant Staphylococcus aureus
    Andrew D Berti
    University of Wisconsin Madison School of Pharmacy, Pharmacy Practice Division, Madison, Wisconsin, USA
    Antimicrob Agents Chemother 57:5005-12. 2013
    ..We suspect that PBP1 disruption by β-lactam antibiotics affects pathways of cell division in S. aureus that may be a compensatory response to DAP membrane insertion, resulting in DAP hypersusceptibility. ..
  12. pmc Altering the proclivity towards daptomycin resistance in methicillin-resistant Staphylococcus aureus using combinations with other antibiotics
    Andrew D Berti
    Pharmacy Practice Division, University of Wisconsin Madison School of Pharmacy, Madison, Wisconsin, USA
    Antimicrob Agents Chemother 56:5046-53. 2012
    ..These data suggest that combining DAP with oxacillin or clarithromycin may delay the development of DAP resistance in cases requiring prolonged antibiotic therapy...
  13. doi request reprint Daptomycin dosing based on ideal body weight versus actual body weight: comparison of clinical outcomes
    Jennifer K Ng
    University of Wisconsin Hospital and Clinics, Madison, Wisconsin, USA
    Antimicrob Agents Chemother 58:88-93. 2014
    ..Further studies are warranted to confirm that ideal body weight dosing provides similar outcomes to actual body weight dosing for all patients and types of infections and organisms. ..