Donald J Roohk

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone
    Donald J Roohk
    Department of Nutritional Sciences and Toxicology, 309 Morgan Hall, University of California, Berkeley, CA 94720 3104, USA
    J Pharmacol Exp Ther 333:281-9. 2010
  2. pmc Dexamethasone-mediated changes in adipose triacylglycerol metabolism are exaggerated, not diminished, in the absence of a functional GR dimerization domain
    Donald J Roohk
    Department of Nutritional Science and Toxicology, University of California Berkeley, Berkeley, California 94720, USA
    Endocrinology 154:1528-39. 2013
  3. doi request reprint Improvements in body fat distribution and circulating adiponectin by alternate-day fasting versus calorie restriction
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, CA 94720, USA
    J Nutr Biochem 21:188-95. 2010
  4. ncbi request reprint Alternate-day fasting reduces global cell proliferation rates independently of dietary fat content in mice
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, California, USA
    Nutrition 25:486-91. 2009

Detail Information

Publications4

  1. doi request reprint Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone
    Donald J Roohk
    Department of Nutritional Sciences and Toxicology, 309 Morgan Hall, University of California, Berkeley, CA 94720 3104, USA
    J Pharmacol Exp Ther 333:281-9. 2010
    ..Because multiple actions can be measured concurrently in a single animal, this method is a powerful systems approach for characterizing and differentiating the effects of ligands that bind nuclear receptors...
  2. pmc Dexamethasone-mediated changes in adipose triacylglycerol metabolism are exaggerated, not diminished, in the absence of a functional GR dimerization domain
    Donald J Roohk
    Department of Nutritional Science and Toxicology, University of California Berkeley, Berkeley, California 94720, USA
    Endocrinology 154:1528-39. 2013
    ..In conclusion, some metabolic effects of GC treatment are exaggerated in adipose tissue of GR(dim/dim) mice, suggesting that selective GR modulators based on dissociating GR transactivation from repression should be evaluated carefully...
  3. doi request reprint Improvements in body fat distribution and circulating adiponectin by alternate-day fasting versus calorie restriction
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, CA 94720, USA
    J Nutr Biochem 21:188-95. 2010
    ..These findings indicate that ADF (both modified and true) produces similar beneficial modulations in body fat distribution and adiponectin levels as daily CR...
  4. ncbi request reprint Alternate-day fasting reduces global cell proliferation rates independently of dietary fat content in mice
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, California, USA
    Nutrition 25:486-91. 2009
    ..Accordingly, we examined the effects of 85% restriction on the fast day (ADF-85%) with an LF or HF background diet on proliferation rates of various tissues...