Research Topics
Genomes and GenesSpecies | Matthew T RondinaSummaryAffiliation: University of Utah Country: USA Publications
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Publications
Weight-based dosing of enoxaparin for VTE prophylaxis in morbidly obese, medically-Ill patientsMatthew T Rondina
Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84132, USA
Thromb Res 125:220-3. 2010....
Methicillin-resistant Staphylococcus aureus-induced thrombo-inflammatory response is reduced with timely antibiotic administrationZ Franks
Matthew T Rondina, MD, University of Utah, Department of Internal Medicine, 50 North Medical Drive, Room 4B120, SLC, Utah 84132, USA, Tel 1 801 581 7818, Fax 1 801 585 1393, E mail
Thromb Haemost 109:684-95. 2013..These data provide novel mechanistic evidence of the importance of prompt antibiotic administration in infectious syndromes...
Whole blood flow cytometry measurements of in vivo platelet activation in critically-Ill patients are influenced by variability in blood sampling techniquesMatthew T Rondina
Divisions of General Internal Medicine, Department of Internal Medicine, Program in Molecular Medicine University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Thromb Res 129:729-35. 2012..Flow cytometry is often used to measure in vivo platelet activation in critically-ill patients. Variability in blood sampling techniques, which may confound these measurements, remains poorly characterized...
In vivo platelet activation in critically ill patients with primary 2009 influenza A(H1N1)Matthew T Rondina
Division of General Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA
Chest 141:1490-5. 2012..Changes in platelet reactivity during 2009 influenza A(H1N1) (A[H1N1]) have not been characterized...
A pilot study utilizing whole body 18 F-FDG-PET/CT as a comprehensive screening strategy for occult malignancy in patients with unprovoked venous thromboembolismMatthew T Rondina
Division of General Internal Medicine, University of Utah, Salt Lake City, Utah 84132, USA
Thromb Res 129:22-7. 2012..In a pilot study, we prospectively investigated the use of FDG-PET/CT to screen for occult malignancy in 40 patients with unprovoked VTE...
The septic milieu triggers expression of spliced tissue factor mRNA in human plateletsM T Rondina
Division of General Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
J Thromb Haemost 9:748-58. 2011..A novel pathway involves splicing of pre-mRNAs in resting platelets to mature, translatable mRNAs in response to cellular activation...
Drug-induced thrombocytopenia for the hospitalist physician with a focus on heparin-induced thrombocytopeniaMatthew T Rondina
Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
Hosp Pract (1995) 38:19-28. 2010..Because patients with HIT have a high risk of thrombosis and bleeding is uncommon, the prompt initiation of an alternative anticoagulant (e.g., a direct thrombin inhibitor) is warranted in these patients...
The treatment of venous thromboembolism in special populationsMatthew T Rondina
The University of Utah Health Sciences Center, Department of Internal Medicine, Salt Lake City, UT 84132, USA
Thromb Res 119:391-402. 2007..This review summarizes the current data for these special patient populations with venous thromboembolism and provides our recommendations for management...
Abdominal aortitis due to Streptococcus pneumoniae and Enterobacter aerogenes: a case report and reviewMatthew T Rondina
Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
J Gen Intern Med 21:C1-3. 2006..Clinicians should maintain a high index of suspicion for infectious aortitis as the mortality, if only treated medically, approaches 100%...
Soluble CD40 ligand as a predictor of coronary artery disease and long-term clinical outcomes in stable patients undergoing coronary angiographyMatthew T Rondina
Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Cardiology 109:196-201. 2008..We evaluated sCD40L levels and future cardiovascular events in patients not experiencing ACS...
The accuracy of activated partial thromboplastin times when drawn through a peripherally inserted central catheterMatthew T Rondina
Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
Am J Hematol 82:738-9. 2007..There were no clinically significant differences between aPTT values from the two samples. Using the PICC to obtain blood for the measurement of aPTT is accurate and may reduce the need for peripheral VPs...
(18)F-FDG PET in the evaluation of acuity of deep vein thrombosisMatthew T Rondina
Division of General Internal Medicine, Department of Internal Medicine, University of Utah, Salt Lake City, UT 84132, USA
Clin Nucl Med 37:1139-45. 2012..F-FDG PET has been used for vascular disease, but its role in deep vein thrombosis (DVT) remains prospectively unexplored...
Prospective comparison of three enoxaparin dosing regimens to achieve target anti-factor Xa levels in hospitalized, medically ill patients with extreme obesityAndrew Freeman
Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA
Am J Hematol 87:740-3. 2012..5 mg/kg QDay is superior to FD and LD enoxaparin for the achievement of target anti-Factor Xa levels...
Argatroban dose reductions for suspected heparin-induced thrombocytopenia complicated by child-pugh class C liver diseasePeter M Yarbrough
Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA
Ann Pharmacother 46:e30. 2012....
Peri-procedural anticoagulation in patients undergoing ablation for atrial fibrillationSara R Vazquez
University of Utah Thrombosis Service, University of Utah, Department of Pharmacy Services, 675 Arapeen Drive, Suite 100, Salt Lake City, UT 84108, USA
Thromb Res 126:e69-77. 2010..In accordance with national guidelines, warfarin should be continued post-ablation for a minimum of 2 months and then indefinitely in patients with a CHADS(2) score >or= 2...
Bacteria differentially induce degradation of Bcl-xL, a survival protein, by human plateletsBjoern F Kraemer
The Molecular Medicine Program, University of Utah, Salt Lake City, UT 84112, USA
Blood 120:5014-20. 2012....
Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human plateletsHansjorg Schwertz
Department of Internal Medicine, University of Utah, Salt Lake City, UT 84112, USA
J Exp Med 203:2433-40. 2006..We propose that platelet-derived TF contributes to the propagation and stabilization of a thrombus...
Carvedilol increases blood pressure response to phenylephrine infusion in heart failure subjects with systolic dysfunction: evidence of improved vascular alpha1-adrenoreceptor signal transductionBenjamin W Van Tassell
Department of Pharmacotherapy, University of Utah, Salt Lake City, UT 84112, USA
Am Heart J 156:315-21. 2008..We examined alpha(1)-AR signal transduction by repeat phenylephrine (PE) infusions in patients with HF receiving chronic carvedilol therapy...
Platelet-leukocyte interactions link inflammatory and thromboembolic events in ischemic strokeZechariah G Franks
Program in Molecular Medicine, University of Utah, Salt Lake City, Utah, USA
Ann N Y Acad Sci 1207:11-7. 2010..In addition to mitigating thrombosis, antiplatelet drugs have direct and indirect effects on inflammation, which may translate to enhanced clinical efficacy...
Azathioprine-induced warfarin resistanceSara R Vazquez
UDepartment of Pharmacy Services, University Thrombosis Service, University of Utah, Salt Lake City, UT 84108, USA
Ann Pharmacother 42:1118-23. 2008..To describe a case of azathioprine-induced warfarin resistance, present a literature review on warfarin-azathioprine interactions, and provide recommendations on appropriate management of this clinically significant interaction...
Prevention of venous thromboembolism in obesityAndrew L Freeman
University of Utah Department of Internal Medicine, 50 North Medical Drive, Room 4B120, School of Medicine, Salt Lake City, UT 84132, USA
Expert Rev Cardiovasc Ther 8:1711-21. 2010..With the prevalence of morbid obesity continuing to rise, more high-quality clinical data are needed to better understand the pathobiology of VTE in obesity and provide effective, yet safe, prevention strategies...
Contemporary issues in the prevention and management of postthrombotic syndromeSara R Vazquez
University of Utah Thrombosis Service, Department of Pharmacy Services, University of Utah, Salt Lake City, UT, USA
Ann Pharmacother 43:1824-35. 2009..To provide an evidence-based review and clinical summary of postthrombotic syndrome (PTS)...
Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 αAlison M McInturff
Department of Pediatrics Neonatology, University of Utah, Salt Lake City, UT 84108, USA
Blood 120:3118-25. 2012..Our studies define a pathway to NET formation involving 2 master regulators of immune cell function and identify potential points of molecular intervention in strategies to modify NETs in disease...
Achieving National Cholesterol Education Program goals in coronary artery diseaseMatthew T Rondina
The Heart Center, 1160 East 3900 South, Suite 2000, Salt Lake City, UT 84124, USA
Prev Cardiol 8:18-22. 2005..We concluded that the majority of CAD patients have had recent lipid measurements and are treated according to NCEP guidelines, but many patients remain on suboptimal therapy...
